Oktenidin Hidrokloridin Doku Çözücü Etkisinin Geleneksel İrrigasyon Solüsyonlarıyla Karşılaştırılması.

GÜNEŞER, Mehmet Burak; AKBULUT, Makbule Bilge; ÜNVERDİ ELDENİZ, Ayçe

Objective: The aim of this study was to compare the tissue-dissolution efficacy of octenidine hydrochloride (OCT) as a new antiseptic solution with sodium hypochlorite solutions (2.5% and 5.25% NaOCl); 17% ethylenediamine tetraacetic acid (EDTA); 2% chlorhexidine and saline solution on bovine palatal tissue in vitro. Material and Methods: Frozen tissue samples obtained from bovine palates were cut into pieces of 4x4x2 mm and thawed at room temperature before use. The samples were randomly divided into five test groups and a control group (n=20 per group): Group 1 (2.5% NaOCl); Group 2 (5.25% NaOCl); Group 3 (17% EDTA); Group 4 (2% chlorhexidine); Group 5 (OCT) and control group (saline solution) and then weighed with a precision balance before placing in separate glass vials containing 5 mL of each test solution with two different temperatures; room temperature (n=10) or 45°C degrees (n=10). After incubation for 1h, samples were washed in saline, blotted dry and weighed again. The percentage of weight loss was calculated and statistically analysed with one-way ANOVA and Tukey post-hoc tests. Results: 5.25% NaOCl solution dissolved the tissue samples more effectively than other solutions (p<0.05). No statistically significant difference was found between the tissue weight loss of OCT and saline groups (p>0.05). Tissue-dissolving efficacy of 2.5% NaOCl, EDTA and chlorhexidine with 45°C was statistically higher than control group (p<0.05). Conclusion: Within the limitations of this in vitro study, it can be concluded that OCT did not have any organic tissue dissolution capacity when compared with other irrigants currently in use in endodontics.

Turkiye Klinikleri Journal of Dental Sciences, 2015, Vol 21, Issue 2, p117

1300-7734

Academic Journal

10.5336/dentalsci.2014-42705