Pulmonary Sclerosing Hemangioma Exhibiting a High KI-67 Proliferation Index.

Akyıldız, Elif Ülker; Bayram, Sami; Arıcı, Akgül; Kasap, Mehtap

Pulmonary sclerosing hemangioma (PSH) is a rare pulmonary neoplasm. This tumour was originally thought to be a variant lesion of hemangioma. Today, however, it has been elucidated to be a tumour of epithelial origin derived from the primitive respiratory epithelium. Previous studies have reported a low Ki-67 proliferation index in cases of pulmonary sclerosing hemangioma (1.4-2.2%). Moreover, the biological nature of this neoplasm, which rarely tends to metastasise to the lymph nodes, has yet to be thoroughly elucidated. A female patient in whom PSH exhibiting a high Ki-67 proliferation index was detected in the lung during follow-up for lymphoma is reported in the present study. While the Ki 67 proliferation index was 3-4% in some areas, it increased up to 15-20% in other areas. No recurrence or metastases were evident at postoperative follow-up.

HEMANGIOMAS; LUNG tumors; CANCER cell proliferation; EPITHELIAL cells; CANCER relapse; METASTASIS; IMMUNOHISTOCHEMISTRY; FOLLOW-up studies (Medicine)

Erciyes Medical Journal / Erciyes Tip Dergisi, 2012, Vol 34, Issue 3, p144

2149-2247

Academic Journal

10.5152/etd.2012.28