Title: FORMULATION AND DEVELOPMENT OF GEL WITH ESSENTIAL OILS AND EFFECT OF POLYMER ON THEIR ANTIMICROBIAL ACTIVITY.
Authors: Uvaraja, V. C.; Keservani, Raj K.; Maurya, Neelesh Kumar; Pendakur, Balaji; Adhoni, Shakeel Ahmed
Abstract: This study made a gel from plant extracts and essential oils to assess its germ-killing power. Plants were collected and extracted with the correct solvent. Distinct polymer and extract amounts produced distinct gels. Both the cup plate and twofold dilution methods were used to measure the zone of inhibition and minimal inhibitory concentration. A minimum bacteria-killing amount was discovered. The study examined how bacteria react to store-bought products. To determine how plant items and essential oils affected antibacterial activity when mixed with polymer gel, the minimum inhibitory concentration was tested before producing the gel. Best results were obtained with propylene glycol as the fluid and carbopol 940 as the gelling agent. Physical qualities examined included gel colour, clarity, pH, stability, spreadability, and viscosity. Adding plant components to the gel didn't boost its effectiveness.
Subjects: ESSENTIAL oils; ANTIMICROBIAL polymers; ANTI-infective agents; PLANT extracts; POLYMER colloids; PROPYLENE glycols; POLYMERS
Publication: Biochemical & Cellular Archives, 2024, Vol 24, Issue 2, p2269
ISSN: 0972-5075
Publication type: Academic Journal
DOI: 10.51470/bca.2024.24.2.2269

FORMULATION AND DEVELOPMENT OF GEL WITH ESSENTIAL OILS AND EFFECT OF POLYMER ON THEIR ANTIMICROBIAL ACTIVITY.

Uvaraja, V. C.; Keservani, Raj K.; Maurya, Neelesh Kumar; Pendakur, Balaji; Adhoni, Shakeel Ahmed