During the management practices in fish farming, the use of anesthetic drugs can configure a security to the producer, as these products have the ability to reduce the metabolism of animals. The present study aimed to find the best dose of benzocaine, eugenol for anesthesia induction, recovery in 'mandi-pintado' juvenile. One hundred, four fish with an average weight of 55.6 ± 15.3 g, mean total length 18.4 ± 1.4 cm were used. The study was conducted in a completely randomized design with 13 treatments, i.e. seven different concentrations of eugenol (40, 70, 100, 130, 160, 190, 220 mg L-1), six concentrations of benzocaine (125, 150, 175, 200, 225, 250 mg L-1), where for each treatment eight randomly chosen fish (n = 8) were used, exposed individually for each concentration. Eugenol for anesthesia was effective in 'mandi-pintado' in different doses. However, benzocaine concentration of 125 mg L-1 was not efficient. Under the experimental conditions, the best concentration of eugenol for anesthesia induction, recovery in 'mandi-pintado' was 70 mg L-1, of benzocaine was 200 mg L-1.