The Mato Grosso state has soy as the main activity in agricultural sector. While in the 1997/98 harvest the average profit reached by producers per sack of soybeans in Mato Grosso was R$2,39, in the 2015/16, harvest this profit increased to R$31,30 per sack. This process of increasing the rate of profit has become an important factor that has been transforming the economic dynamics of both endogenous and exogenous investments. The objective this article is to unravel the capacity of capital accumulation of agribusiness in Mato Grosso and the territorial configurations resulting from this accumulation. To achieve the objective, used four methodological steps: 1) data collection and bibliographic survey, 2) fieldwork and technical visits, 3) organization and treatment of data and information collected and 4) data analysis. One of the principally results found was that the capital accumulated in agribusiness of Mato Grosso promote territorial changes both in agribusiness itself in the cities.