Acute neonatal suppurative parotitis (ANSP) is a rare disease and a novel illness affecting newborns and premature neonates are more likely to contract it. A unilateral parotid swelling and pus discharge from the Stensen's duct is pathognomonic and sonography is the first line tool to supplement the diagnosis of parotitis. An appropriate parenteral antibiotic therapy and adequate hydration are the mainstays of treatment. Herein, we report a case of ANSP in a 12-day-old baby girl with a 48-hour history of left pre-auricular swelling where a complete resolution of disease was achieved post-treatment.