Background: Nutritional aspects among adolescents can arise due to incorrect eating habits, leading to an imbalance between nutritional consumption and recommendation, which may result in underweight, overweight, and anemia. Boarding schools are especially susceptible to these issues as they often offer limited food options with behaviors and patterns of skipping eating. This research aims to assess the effect of Multiple Micronutrient Supplements (MMS) and balanced nutritional education on the hemoglobin levels of adolescent girls in boarding schools. Method: Quantitative research using a case study approach with a one-group pretest-posttest design in 53 teenage girls at boarding school. The intervention consists of nutritional education and MMS, once a week for three months, combined with a persuasive intervention approach to implement food at the boarding school to assess the effect on hemoglobin levels. Data analysis was carried out using SPSS 25, which includes the Shapiro-Wilk and Wilcoxon tests. Results: The research found a significant improvement in the nutritional and hemoglobin levels of the respondents after the intervention. The average z-score of nutritional status increased from -0.208 ± 1.08 (normal) to -0.047 ± 0.89 (normal), with a p-value of 0.031 (<0.05). Similarly, the average hemoglobin level increased from 11.9 g/dL (anemia) to 12.6 g/dL (not anemic), with a p-value of 0.0001 (<0.05). These results indicate a notable difference between the average before and after the intervention. Conclusion: The intervention provides multiple micronutrient supplements and nutritional education based on the "Aksi Bergizi" program at the boarding school, significantly improving the hemoglobin levels of adolescent girls in boarding schools.