Results
Title

THE IMPACT OF MICROSURGICAL VARICOCELECTOMY ON SERUM TESTOSTERONE LEVEL AND SEMEN PARAMETERS IN SUBFERTILE MEN WITH CLINICALLY EVIDENT TESTICULAR VARICOCELE.

Authors

Hussein, Ahmed Mahmood; Ismael Sefer, Ayad Abdukhaleq; Saber, Alan Adnan

Abstract

Background: Testicular varicocele is a prevalent condition contributing to male infertility by disrupting spermatogenesis and reducing testosterone production. This study aimed to evaluate the impact of sub-inguinal microscopic varicocelectomy on serum testosterone levels and seminal fluid parameters in subfertile men. Materials & Methods: This prospective study was conducted in the Azadi Teaching Hospital in Kirkuk between January 2023 and February 2024. Fifty men, aged 19-45, diagnosed with unilateral or bilateral varicocele and abnormal semen parameters (oligo-, astheno-, or oligoasthenoteratospermia) were recruited. Infertility duration exceeded three years in all cases. Exclusion criteria included azoospermia or normal semen profiles. Varicocele was confirmed via physical examination and scrotal ultrasound. Preoperative and six-month postoperative serum testosterone levels and seminal parameters were compared. Data collection involved standardized hormonal assays and semen analyses, with statistical analysis conducted to determine significance. Results: Of the participants, 76% had left-sided varicocele, and 24% had bilateral involvement. Postoperative serum testosterone levels significantly increased from 3.18 ±0.88 to 4.07 ±0.70 ng/ml (p <0.001). Sperm motility also improved significantly from 17.2% ±7.43% to 27.4% ±8.22% (p <0.001). However, sperm count and morphology showed no statistically significant changes after surgery (p >0.05). Conclusion: Sub-inguinal microscopic varicocelectomy is effective in improving testosterone levels and sperm motility in men with varicocele. Despite these benefits, no significant enhancements were observed in sperm count or morphology, suggesting a partial therapeutic impact on seminal parameters.

Subjects

SEMEN analysis; MALE infertility; SPERM motility; VARICOCELECTOMY; SPERM count

Publication

Gomal Journal of Medical Sciences, 2024, Vol 22, Issue 4, p359

ISSN

1819-7973

Publication type

Academic Journal

DOI

10.46903/gjms/22.04.1794