Works matching DE "LIFE sciences"

Results: 5000

Structure-based design of potent and selective inhibitors of the HECT ligase NEDD4.

Published in:

Communications Chemistry, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42004-025-01557-4

By:

Maspero, Elena;
Cappa, Anna;
Weber, Janine;
Trifirò, Paolo;
Amici, Raffaella;
Bruno, Agostino;
Fagà, Giovanni;
Cecatiello, Valentina;
Fattori, Raimondo;
Leuzzi, Brian;
Taibi, Vincenzo;
Meroni, Giuseppe;
Pasi, Maurizio;
Romussi, Alessia;
Sartori, Luca;
Villa, Manuela;
Vultaggio, Stefania;
Cirò, Marco;
Soffientini, Paolo;
Lombardo, Lierin

Publication type:

Article

Discovery and chemical optimisation of a potent, Bi-cyclic antimicrobial inhibitor of Escherichia coli PBP3.

Published in:

Communications Biology, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42003-025-08246-x

By:

Rowland, Catherine E.;
Newman, Hector;
Martin, Tazmin T.;
Dods, Rachel;
Bournakas, Nikolaos;
Wagstaff, James M.;
Lewis, Nick;
Stanway, Steven J.;
Balmforth, Matthew;
Kessler, Celia;
van Rietschoten, Katerine;
Bellini, Dom;
Roper, David I.;
Lloyd, Adrian J.;
Dowson, Christopher G.;
Skynner, Michael J.;
Beswick, Paul;
Dawson, Michael J.

Publication type:

Article

Plasticity in the Life Sciences.

Published in:

2025

By:

Ione, Amy

Publication type:

Book Review

Chromosome-level genome assembly of Sambus kanssuensis (Coleoptera: Buprestidae).

Published in:

Scientific Data, 2025, v. 12, n. 1, p. 1, doi. 10.1038/s41597-025-05271-7

By:

Wei, Zhonghua;
Li, Yunchun;
Li, Yingying;
Liu, Jiuzhou;
Ding, Shuangmei;
Chen, Xulong;
Shi, Aimin;
Yang, Ding

Publication type:

Article

Mass Spectral Data of Primary and Secondary Metabolites Changes in Medicinal Plants by Solvent Polarity.

Published in:

Scientific Data, 2025, v. 12, n. 1, p. 1, doi. 10.1038/s41597-025-05262-8

By:

Park, Jinyoung;
Lee, Jiho;
Cho, Chaeyeon;
Lee, Dong Kyo;
Song, Woohyun;
Choi, Kyeongwon;
Choi, Seong Yeon;
Yang, Heejung

Publication type:

Article

Chromosome-level genome assembly of scalloped spiny lobster Panulirus homarus homarus.

Published in:

Scientific Data, 2025, v. 12, n. 1, p. 1, doi. 10.1038/s41597-025-05253-9

By:

Sun, Dongfang;
Lv, Jianjian;
Gao, Baoquan;
Jia, Shaoting;
Liu, Ping;
Li, Jian;
Li, Jitao;
Ren, Xianyun

Publication type:

Article

InsectGUILD: feeding guilds of lepidopteran and hymenopteran larvae consuming Northern Hemisphere woody plants.

Published in:

Scientific Data, 2025, v. 12, n. 1, p. 1, doi. 10.1038/s41597-025-05229-9

By:

Cerdeira-Pérez, Andrea;
Laanisto, Lauri;
Puglielli, Giacomo

Publication type:

Article

A chromosomal-level genome assembly of Araneus marmoreus Schenkel, 1953 (Araneae: Araneidae).

Published in:

Scientific Data, 2025, v. 12, n. 1, p. 1, doi. 10.1038/s41597-025-05215-1

By:

Wang, Lu-Yu;
Xiao, Lin;
Ren, Tian-Yu;
Cheng, Ling-Xin;
Xiong, Jun-Han;
Fan, Zheng;
Zhang, Zhi-Sheng

Publication type:

Article

Transcriptome analysis of testes gene expression to explore genetic diversity of Mangalica and Camborough boars.

Published in:

Scientific Data, 2025, v. 12, n. 1, p. 1, doi. 10.1038/s41597-025-05196-1

By:

Yamane, Keigo;
Kim, Sangwoo;
Koide, Akari;
Yoneda, Erina;
Kayano, Mitsunori;
Muranishi, Yuki

Publication type:

Article

Root-associated microbiota of decline-affected and asymptomatic Pinus sylvestris trees.

Published in:

Scientific Data, 2025, v. 12, n. 1, p. 1, doi. 10.1038/s41597-025-05013-9

By:

Lasa, Ana V.;
Pérez-Luque, Antonio J.;
Fernández-López, Manuel

Publication type:

Article

ECONOMIC REINVENTION THROUGH BIOMANUFACTURING.

Published in:

2025

By:

Consani, Angela

Publication type:

Letter to the Editor

Detection and Recognition of Visual Geons Based on Specific Object-of-Interest Imaging Technology.

Published in:

Sensors (14248220), 2025, v. 25, n. 10, p. 3022, doi. 10.3390/s25103022

By:

Wu, Yonghao;
Liu, Minyi;
Li, Jun

Publication type:

Article

Correction to: "Inflammation and Prediction of Death in Type 2 Diabetes. Evidence of an Intertwined Link With Tryptophan Metabolism" Open Access.

Published in:: Journal of Clinical Endocrinology & Metabolism, 2025, v. 110, n. 5, p. e1728, doi. 10.1210/clinem/dgaf119
Publication type:: Article

Genetic engineering of E. coli K-12 for heterologous carbohydrate antigen production.

Published in:

Microbial Cell Factories, 2025, v. 24, n. 1, p. 1, doi. 10.1186/s12934-025-02749-2

By:

Li, Caixia;
Zha, Hongxu;
Jiao, Ziyan;
Wei, Keyan;
Gao, Huaiyu;
Lai, Feiyi;
Zhou, Zuoyong;
Luo, Hongyan;
Li, Pei

Publication type:

Article

Marine Bioactive Peptides—Structure, Function, and Application 2.0.

Published in:

Marine Drugs, 2025, v. 23, n. 5, p. 192, doi. 10.3390/md23050192

By:

Wang, Bin;
Chi, Chang-Feng

Publication type:

Article

Characteristics of the gut virome in patients with premalignant colorectal adenoma.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06404-7

By:

Zhang, Pan;
Tuo, Xiaofeng;
Jiang, Jiong;
Zhang, Yue;
Zhao, Juhui;
Deng, Chengzhao;
Zhao, Gang;
Cheng, Yan;
Song, Lingqin;
Yang, Yan;
Guo, Ruochun;
Zhang, Huan;
Zhao, Hongli;
Ma, Shiyang;
Li, Lu;
Shi, Haitao

Publication type:

Article

Impaired membrane lipids in ischemic stroke: a key player in inflammation and thrombosis.

Published in:

Journal of Neuroinflammation, 2025, v. 22, n. 1, p. 1, doi. 10.1186/s12974-025-03464-w

By:

Wang, Qian;
Wang, Dandan;
Gao, Yan;
Jiang, Jie;
Li, Minghui;
Li, Shuhui;
Hu, Xiaowen;
Wang, Jinfeng;
Wang, Tianqi;
Zhang, Juan;
Feng, Lei;
Quan, Chao;
Zhang, Ping;
Zheng, Lan;
Wan, Chunling

Publication type:

Article

BIT: Bayesian Identification of Transcriptional regulators from epigenomics-based query region sets.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-60269-4

By:

Lu, Zeyu;
Xu, Lin;
Wang, Xinlei

Publication type:

Article

RNF20 links the DNA damage response and metabolic rewiring in lung cancer through HIF1α.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-60223-4

By:

Liu, Hao;
Tang, Yongqin;
Singh, Anshu;
Vong, Joaquim;
Cordero, Julio;
Mathes, Arthur;
Gao, Rui;
Jia, Yanhan;
Garvalov, Boyan K.;
Acker, Till;
Poschet, Gernot;
Hell, Rüdiger;
Schneider, Marc A.;
Heineke, Joerg;
Wieland, Thomas;
Barreto, Guillermo;
Cerwenka, Adelheid;
Potente, Michael;
Bibli, Sofia-Iris;
Savai, Rajkumar

Publication type:

Article

Repeated loss of function at HD mating-type genes and of recombination in anther-smut fungi.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-60222-5

By:

Lucotte, Elise A.;
Jay, Paul;
Rougemont, Quentin;
Boyer, Loreleï;
Cornille, Amandine;
Snirc, Alodie;
Labat, Amandine;
Chahine, Elizabeth;
Duhamel, Marine;
Namias, Alice;
Gendelman, Jacob;
Ma, Wen-Juan;
Hayes, Roxanne K.;
Baruri, Shikhi;
Ham, Joseph P.;
Perlin, Michael H.;
Hood, Michael E.;
Rodríguez de la Vega, Ricardo C.;
Giraud, Tatiana

Publication type:

Article

Dietary carbohydrates alter immune-modulatory functionalities and DNA inversions in Bacteroides thetaiotaomicron.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-60202-9

By:

Gal-Mandelbaum, Noa;
Carasso, Shaqed;
Kedem, Alon;
Ziv, Tamar;
Keshet-David, Roni;
Abboud, Roberto;
Zaatry, Rawan;
Gefen, Tal;
Geva-Zatorsky, Naama

Publication type:

Article

Pleiotropic and sex-specific genetic mechanisms of circulating metabolic markers.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-60058-z

By:

van der Meer, Dennis;
Rahman, Zillur;
Ottas, Aigar;
Parekh, Pravesh;
Kutrolli, Gleda;
Stinson, Sara E.;
Koromina, Maria;
Rokicki, Jaroslav;
Sønderby, Ida E.;
Parker, Nadine;
Tesfaye, Markos;
Hindley, Guy;
Rødevand, Linn N.;
Koch, Elise;
Metspalu, Andres;
Esko, Tõnu;
Mägi, Reedik;
Metspalu, Mait;
Nelis, Mari;
Hudjashov, Georgi

Publication type:

Article

An optimized disease resistance gene cloning workflow for wheat.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-60033-8

By:

Wang, Yajun;
Wang, Xiaodong;
Zhang, Lu;
Zhakupova, Kymbat;
Ayala, Francisco;
Ouyang, Yi;
Lu, Jing;
Athiyannan, Naveenkumar;
Wulff, Brande B. H.;
Krattinger, Simon G.

Publication type:

Article

Divergent molecular pathways govern temperature-dependent wheat stem rust resistance genes.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-60030-x

By:

Hewitt, Tim C.;
Sharma, Keshav;
Zhang, Jianping;
Chen, Chunhong;
Bajgain, Prabin;
Bhatt, Dhara;
Singh, Smriti;
Olivera Firpo, Pablo D.;
Yang, Jun;
Wang, Qiaoli;
Upadhyaya, Narayana;
Pozniak, Curtis;
McIntosh, Robert;
Lagudah, Evans;
Zhang, Peng;
Rouse, Matthew N.

Publication type:

Article

Genome-wide association studies in a large Korean cohort identify quantitative trait loci for 36 traits and illuminate their genetic architectures.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-59950-5

By:

Jee, Yon Ho;
Wang, Ying;
Jung, Keum Ji;
Lee, Ji-Young;
Kimm, Heejin;
Duan, Rui;
Price, Alkes L.;
Martin, Alicia R.;
Kraft, Peter

Publication type:

Article

Multiple structures of RNA polymerase II isolated from human nuclei by ChIP-CryoEM analysis.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-59580-x

By:

Kujirai, Tomoya;
Kato, Junko;
Yamamoto, Kyoka;
Hirai, Seiya;
Fujii, Takeru;
Maehara, Kazumitsu;
Harada, Akihito;
Negishi, Lumi;
Ogasawara, Mitsuo;
Yamaguchi, Yuki;
Ohkawa, Yasuyuki;
Takizawa, Yoshimasa;
Kurumizaka, Hitoshi

Publication type:

Article

Shedding light on the cell biology and diverse physiological functions of the migrasome.

Published in:

Cell & Bioscience, 2025, v. 15, n. 1, p. 1, doi. 10.1186/s13578-025-01417-7

By:

Huang, Yuxing;
Huang, Yi;
Gao, Jian

Publication type:

Article

Rab11a-dependent recycling of Glut3 inhibits seizure-induced neuronal disulfidptosis by alleviating glucose deficiency.

Published in:

Cell & Bioscience, 2025, v. 15, n. 1, p. 1, doi. 10.1186/s13578-025-01396-9

By:

Li, Sijun;
He, Junrui;
Kuang, Huimin;
Wang, Xiaojuan;
Zhou, Muhua;
Li, Dongmei;
Kang, Baoren;
He, Honghu;
He, Lina;
Lin, Wei;
Lv, Yuan

Publication type:

Article

The MEK5/ERK5 pathway promotes the activation of the Hedgehog/GLI signaling in melanoma cells.

Published in:

Cellular Oncology (2211-3428), 2025, v. 48, n. 3, p. 789, doi. 10.1007/s13402-025-01050-z

By:

Tusa, Ignazia;
Gagliardi, Sinforosa;
Menconi, Alessio;
Maresca, Luisa;
Tubita, Alessandro;
Lulli, Matteo;
Stecca, Barbara;
Rovida, Elisabetta

Publication type:

Article

Exosomes delivering miR-129-5p combined with sorafenib ameliorate hepatocellular carcinoma progression via the KCTD1/HIF-1α/VEGF pathway.

Published in:

Cellular Oncology (2211-3428), 2025, v. 48, n. 3, p. 743, doi. 10.1007/s13402-025-01044-x

By:

Zhu, Xinyu;
Li, Zhiwei;
Chen, Li;
Li, Limin;
Ouyang, Mi;
Zhou, Hao;
Xiao, Kai;
Lin, Ling;
Chu, Paul K.;
Zhou, Chang;
Xun, Chengfeng;
Yang, Liu;
Huang, Wenhuan;
Ding, Xiaofeng

Publication type:

Article

LPA released from dying cancer cells after chemotherapy inactivates Hippo signaling and promotes pancreatic cancer cell repopulation.

Published in:

Cellular Oncology (2211-3428), 2025, v. 48, n. 3, p. 655, doi. 10.1007/s13402-025-01038-9

By:

Liu, Yuzhi;
Ding, Jie;
Li, Shumin;
Jiang, Anyi;
Chen, Zhiqin;
Quan, Ming

Publication type:

Article

UBE2Q2 promotes tumor progression and glycolysis of hepatocellular carcinoma through NF-κB/HIF1α signal pathway.

Published in:

Cellular Oncology (2211-3428), 2025, v. 48, n. 3, p. 637, doi. 10.1007/s13402-025-01037-w

By:

Wu, Xiaoling;
Chen, Yiran;
He, Wenzhi;
Yao, Ye;
Liu, Yingyi;
Xia, Peng;
Zhang, Hao;
Li, Xiaomian;
Guo, Yonghua;
Chen, Xi;
Ma, Weijie;
Yuan, Yufeng

Publication type:

Article

Three-dimensional genome architecture in intrahepatic cholangiocarcinoma.

Published in:

Cellular Oncology (2211-3428), 2025, v. 48, n. 3, p. 617, doi. 10.1007/s13402-024-01033-6

By:

Liang, Youfeng;
Li, Cong;
Zou, Renchao;
Ying, Lu;
Chen, Xiaoyang;
Wang, Zhaohai;
Zhang, Wenjing;
Hao, Mingxuan;
Yang, Hao;
Guo, Rui;
Lei, Guanglin;
Sun, Fang;
Zhao, Kexu;
Zhang, Yu;
Dai, Jia;
Feng, Shangya;
Zhang, Keyue;
Guo, Luyuan;
Liu, Shuyue;
Wan, Chuanxing

Publication type:

Article

Possibility.

Published in:

2025

By:

Harper, Graeme

Publication type:

Editorial

Antimicrobial activity, synthesis, and docking study of some novel arylazo-1,3-thiazolopyrimidine and arylazo-1,3-thiazolopyridopyrimidine derivatives.

Published in:

BMC Chemistry, 2025, v. 19, n. 1, p. 1, doi. 10.1186/s13065-025-01506-1

By:

Qurban, Jihan;
Alqarni, Sara A.;
Alalawy, Adel I.;
Alshammari, Nawaa Ali H.;
Ashour, Gadeer R. S.;
Alnoman, Maryam M.;
Katuah, Hanadi A.;
El-Metwaly, Nashwa M.

Publication type:

Article

NOXA exacerbates endoplasmic-reticulum-stress-induced intervertebral disc degeneration by activating apoptosis and ECM degradation.

Published in:

Cell Death Discovery, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41420-025-02539-0

By:

Liu, Zhiming;
Lu, Hui;
Zhang, Xianjuan;
Tang, Shuai;
Lin, Antao;
Han, Shuo;
Ma, Xuexiao

Publication type:

Article

Cracking rare disorders: a new minimally invasive RNA-seq protocol.

Published in:

NPJ Genomic Medicine, 2025, v. 10, n. 1, p. 1, doi. 10.1038/s41525-025-00502-7

By:

De Cock, Laurenz;
D'haenens, Erika;
Vantomme, Lies;
Backers, Lynn;
Beyens, Aude;
Claes, Kathleen BM;
De Clercq, Griet;
de Putter, Robin;
Kumps, Candy;
Schuermans, Nika;
Sourbron, Jo;
Syryn, Hannes;
Tavernier, Simon;
Vanbelleghem, Eva;
Vanakker, Olivier;
Vandekerckhove, Bart;
Van Damme, Tim;
Callewaert, Bert;
Dheedene, Annelies;
Vergult, Sarah

Publication type:

Article

Präzisere Bauplanung für Life-Science-Projekte.

Published in:: Pharma + Food, 2025, p. 12
Publication type:: Article

Nomenclature for Factors of the HLA System, Update January, February, and March 2025.

Published in:

HLA: Immune Response Genetics, 2025, v. 105, n. 5, p. 1, doi. 10.1111/tan.70203

By:

Marsh, Steven G. E.

Publication type:

Article

Technical approaches of 3D reconstruction from protein complex using the mixture of differently stained images: providing suggestive evidence for improving its resolution.

Published in:

Applied Microscopy, 2025, v. 55, n. 1, p. 1, doi. 10.1186/s42649-025-00111-9

By:

Park, Yoon Ho;
Jeong, Myeong Seon;
Song, Gang San;
gwonbaek, Tak;
Kim, Young Kwan;
Jung, Hyun Suk

Publication type:

Article

Exploring urban garden ponds: considering chemical pollution as a limiting factor for insect diversity in cities.

Published in:

Environmental Sciences Europe, 2025, v. 37, n. 1, p. 1, doi. 10.1186/s12302-025-01120-x

By:

Bock, Johanna;
Neske, Marie;
Krauss, Martin;
Dombrowski, Andrea;
Oehlmann, Jörg

Publication type:

Article

Marx' Antwort auf den Mythos des Gegebenen.

Published in:

Deutsche Zeitschrift für Philosophie, 2024, v. 72, n. 6, p. 815, doi. 10.1515/dzph-2024-0061

By:

Vaccarino Bremner, Sabina

Publication type:

Article

Correction: Urbánek et al. Controlled Drug Delivery Device for Cornea Treatment and Novel Method for Its Testing. Pharmaceuticals 2023, 16 , 505.

Published in:

2025

By:

Urbánek, Pavel;
Šuly, Pavol;
Ševčík, Jakub;
Hanulíková, Barbora;
Kuřitka, Ivo;
Šopík, Tomáš;
Rafat, Mehrdad;
Stodůlka, Pavel

Publication type:

Correction Notice

Tumor-associated macrophages contribute to cisplatin resistance via regulating Pol η-mediated translesion DNA synthesis in ovarian cancer.

Published in:

Cellular & Molecular Life Sciences, 2025, v. 82, n. 1, p. 1, doi. 10.1007/s00018-025-05731-8

By:

Chatterjee, Bilash;
Sarkar, Mrinmoy;
Ghosh, Debanjana;
Mishra, Sangita;
Bose, Subhankar;
Khan, Md. Maqsood Ahamad;
Ganesan, Senthil Kumar;
Chatterjee, Nabanita;
Srivastava, Amit Kumar

Publication type:

Article

Reprogramming FGF1 from the natural growth factor to the engineered heparan sulphate biosensor.

Published in:

Cell Communication & Signaling, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12964-025-02269-x

By:

Ciura, Krzysztof;
Sobota, Olimpia;
Chorążewska, Aleksandra;
Krowarsch, Daniel;
Porębska, Natalia;
Opaliński, Łukasz

Publication type:

Article

ArcB initiates quorum sensing to regulate T3SS in Vibrio alginolyticus by recognizing bacterial and host-derived autoinducer-2 as a kinase.

Published in:

Cell Communication & Signaling, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12964-025-02258-0

By:

Zhang, Ce;
Jin, Xingkun;
Shi, Yan;
Yu, Fei;
Wu, Ying;
Call, Douglas R.;
Zhao, Zhe

Publication type:

Article

Effect of nanocellulose-assisted green-synthesized iron nanoparticles and conventional sources of Fe on pot marigold plants symbiotically with arbuscular mycorrhizal fungus (Funneliformis mosseae).

Published in:

BMC Plant Biology, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12870-025-06758-6

By:

Nohesara, Maryam;
Malekzadeh, Elham;
Motlagh, Mojtaba Barani;
Tatari, Aliasghar

Publication type:

Article

Effects of spatial setting of LED light source on yield, quality, and water-use efficiency in greenhouse tomato.

Published in:

BMC Plant Biology, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12870-025-06756-8

By:

Zhao, Wang;
Liu, Wenkai;
Meng, Xin;
Jin, Ning;
Jin, Li;
Xu, Zhiqi;
Zhang, Qian;
Sun, Qin;
Zhang, Wei;
Yu, Jihua;
Wang, Shuya;
Lyu, Jian

Publication type:

Article

TcMYB73, a salicylic acid-responsive R2R3-MYB transcription factor, positively regulates paclitaxel biosynthesis in Taxus chinensis in direct and indirect ways.

Published in:

BMC Plant Biology, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12870-025-06755-9

By:

Ren, Yifei;
Liu, Donglin;
Zhao, Weicheng;
Wang, Xinran;
Cao, Xiaoying;
Wan, Wen

Publication type:

Article

Silicon-induced mitigation of salt stress in GF677 and GN15 rootstocks: insights into physiological, biochemical, and molecular mechanisms.

Published in:

BMC Plant Biology, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12870-025-06753-x

By:

Gharbi, Pouya;
Amiri, Jafar;
Mahna, Nasser;
Naseri, Lotfali;
Sadaghiani, MirHassan Rasouli

Publication type:

Article