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Title

Erectile dysfunction: prevalence, risk factors and involvement of antihypertensive drugs intervention.

Authors

Salman, Muhammad; Shehzadi, Naureen; Khan, Muhammad T.; Islam, Muhammad; Amjad, Sohail; Afzal, Omer; Mansoor, Sibghat; Qamar, Shaista; Peerzada, Sohaib; Khan, Amer H.; Hussain, Khalid

Abstract

Purpose: To explore the literature regarding prevalance, risk factors and the involvement of antihypertensive drugs in erectile dysfunction (ED). Methods: Original research articles, reviews, editorials and case reports published in English language on the prevalence of sexual/erectile dysfunction in hypertensive men taking antihypertensive drugs and risk factors were identified through a search of four bibliographic databases, namely, PubMed, EMBASE, CINAHL and EBSCO Health. Results: Recent analyses suggest that hypertensive men of almost all age groups suffer from ED but it is more prevalent in elderly male patients. The involvement of β-blockers was found to be controversial. Nevertheless, some evidence had been found regarding the use of propranolol in high doses. Conclusion: The present review indicates the need for research to unravel the role of β-blockers in the manifestation of ED in hypertensive males, whom there are no contributory factors such as sedentary lifestyle, aging, stress and anxiety, etc.

Subjects

IMPOTENCE risk factors; ANTIHYPERTENSIVE agents; DRUG interactions; HYPERTENSION; PROPRANOLOL; PHYSIOLOGICAL stress; ANXIETY

Publication

Tropical Journal of Pharmaceutical Research, 2016, Vol 15, Issue 4, p869

ISSN

1596-5996

Publication type

Academic Journal

DOI

10.4314/tjpr.v15i4.29

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