Works matching DE "INFLAMMASOMES"

Results: 2648

Shi Wei Ru Xiang pill alleviates acute gouty arthritis through suppressing NLRP3 inflammasome activation.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1595578

By:

Wang, Na;
Zhao, Puchen;
Yin, Qin;
Li, Lizi;
Xu, Haiqi;
Yang, Can;
Tu, Yanbei;
Li, Yanfang

Publication type:

Article

Pyroptosis as a therapeutic target in preeclampsia: current research and future directions.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1622550

By:

Zhu, Yongchun;
Xiang, Yuting;
Swamiappan, Sathiskumar;
Li, Zhongjun;
Peng, Xinsheng

Publication type:

Article

Comparative Analysis of Canonical Inflammasome Activation by Flow Cytometry, Imaging Flow Cytometry and High-Content Imaging.

Published in:

Inflammation, 2025, v. 48, n. 3, p. 1513, doi. 10.1007/s10753-024-02141-z

By:

Wittmann, Nico;
Bekeschus, Sander;
Biedenweg, Doreen;
Kuthning, Daniela;
Pohl, Christopher;
Gramenz, Jana;
Otto, Oliver;
Bossaller, Lukas;
Meyer-Bahlburg, Almut

Publication type:

Article

Hypothermia protects against ventilatorinduced lung injury by limiting IL-1β release and NETs formation.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.101990

By:

Nosaka, Nobuyuki;
Borges, Vanessa;
Martinon, Daisy;
Crother, Timothy R;
Arditi, Moshe;
Shimada, Kenichi

Publication type:

Article

CARD8 inflammasome activation during HIV-1 cell-to-cell transmission.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.102676

By:

Kulsuptrakul, Jessie;
Emerman, Michael;
Mitchell, Patrick S.

Publication type:

Article

The non-structural protein of SFTSV activates NLRP1 and CARD8 inflammasome through disrupting the DPP9-mediated ternary complex.

Published in:

PLoS Pathogens, 2025, v. 21, n. 7, p. 1, doi. 10.1371/journal.ppat.1013258

By:

Liu, Pan-Pan;
Jiang, Shu-Peng;
Li, Bang;
Gui, Wen-Tao;
Qin, Xiang-Rong;
Yu, Xue-Jie

Publication type:

Article

A Case of Persistent Facial Rash in a 15‐Year‐Old: Uncovering Rosacea in the Context of Duchenne Muscular Dystrophy.

Published in:

Dermatological Reviews, 2025, v. 6, n. 3, p. 1, doi. 10.1002/der2.70040

By:

Ward, Kathleen;
Foy, Valerie;
Han, Haowei;
Choudhury, Sourab

Publication type:

Article

Dipeptidyl Peptidase 9 in Human Leukocytes: Novel Inhibitors Induce Caspase‐1‐ and Gasdermin‐Dependent Cell Death.

Published in:

European Journal of Immunology, 2025, v. 55, n. 6, p. 1, doi. 10.1002/eji.202451526

By:

De Loose, Joni;
Mertens, Kathleen;
Filippi, Nicolò;
Corthaut, Sam;
Benramdane, Siham;
Sim, Yani;
Van Rymenant, Yentl;
Claesen, Karen;
Vliegen, Gwendolyn;
Berg, Maya;
Gomard, Tiphanie;
Caljon, Guy;
Pintelon, Isabel;
Van Der Veken, Pieter;
De Meester, Ingrid

Publication type:

Article

mTOR Modulates NLRP3 Inflammasome Activation via Nuclear Translocation and STAT1 Inhibition.

Published in:

European Journal of Immunology, 2025, v. 55, n. 6, p. 1, doi. 10.1002/eji.202451176

By:

González‐Dominguez, Alvaro;
Zhang, Shuling;
Boy‐Ruiz, Daniel;
Connors, Daniel;
de la Varga‐Martínez, Raquel;
Mock, Beverly A.;
Cordero, Mario D.

Publication type:

Article

Inflammasomes in Cardiovascular Diseases: Current Knowledge and Future Perspectives.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 12, p. 5439, doi. 10.3390/ijms26125439

By:

Caldarelli, Mario;
Franza, Laura;
Cutrupi, Sebastiano;
Menegolo, Martina;
Franceschi, Francesco;
Gasbarrini, Antonio;
Gambassi, Giovanni;
Cianci, Rossella

Publication type:

Article

Estimation of NLRP3 Inflammasome Role and some Biochemical Parameters in Patients with Chronic Kidney Diseases (CKD).

Published in:

University of Thi-Qar Journal of Science, 2023, v. 10, n. 2, p. 16, doi. 10.32792/utq/utjsci/v10i2.1063

By:

Alwan, Nada Hussain;
Faraj, Hadeel Rashid

Publication type:

Article

Combination of tauroursodeoxycholic acid and N-acetylcysteine exceeds standard treatment for acetaminophen intoxication.

Published in:

Liver International, 2017, v. 37, n. 5, p. 748, doi. 10.1111/liv.13261

By:

Paridaens, Annelies;
Raevens, Sarah;
Colle, Isabelle;
Bogaerts, Eliene;
Vandewynckel, Yves ‐ Paul;
Verhelst, Xavier;
Hoorens, Anne;
Grunsven, Leo A.;
Van Vlierberghe, Hans;
Geerts, Anja;
Devisscher, Lindsey

Publication type:

Article

Inflammasome and Inflammatory Programmed Cell Death in Chromoblastomycosis.

Published in:

Mycopathologia, 2023, v. 188, n. 1/2, p. 63, doi. 10.1007/s11046-022-00679-w

By:

Pagliari, Carla;
Kanashiro-Galo, Luciane;
Sotto, Mirian Nacagami

Publication type:

Article

Absent in melanoma 2 regulates tumor cell proliferation in glioblastoma multiforme.

Published in:

Journal of Neuro-Oncology, 2019, v. 144, n. 2, p. 265, doi. 10.1007/s11060-019-03230-y

By:

Chen, P. A.;
Shrivastava, G.;
Balcom, E. F.;
McKenzie, B. A.;
Fernandes, J.;
Branton, W. G.;
Wheatley, B. M.;
Petruk, K.;
van Landeghem, F. K. H.;
Power, Christopher

Publication type:

Article

The emerging role of pyroptosis-related inflammasome pathway in atherosclerosis.

Published in:

Molecular Medicine, 2022, v. 28, n. 1, p. 1, doi. 10.1186/s10020-022-00594-2

By:

Xu, Xiao-Dan;
Chen, Jia-Xian;
Zhu, Lin;
Xu, Shu-Ting;
Jiang, Jian;
Ren, Kun

Publication type:

Article

Relevance of the pyroptosis-related inflammasome drug targets in the Chuanxiong to improve diabetic nephropathy.

Published in:

Molecular Medicine, 2022, v. 28, n. 1, p. 1, doi. 10.1186/s10020-022-00567-5

By:

Li, ChangYan;
Ma, JingYuan;
Mali, Niroj;
Zhang, Le;
Wei, Tao;
Shi, LuYao;
Liu, Fang;
WenXing, Fan;
Yang, Jing

Publication type:

Article

Spermidine protects against acute kidney injury by modulating macrophage NLRP3 inflammasome activation and mitochondrial respiration in an eIF5A hypusination-related pathway.

Published in:

Molecular Medicine, 2022, v. 28, n. 1, p. 1, doi. 10.1186/s10020-022-00533-1

By:

Li, Xianzhi;
Zhou, Xiaojun;
Liu, Xigao;
Li, Xiaoyun;
Jiang, Xianzhou;
Shi, Benkang;
Wang, Shuo

Publication type:

Article

Fn14 exacerbates acute lung injury by activating the NLRP3 inflammasome in mice.

Published in:

Molecular Medicine, 2022, v. 28, n. 1, p. 1, doi. 10.1186/s10020-022-00514-4

By:

Guan, Xin-Xin;
Yang, Hui-Hui;
Zhong, Wen-Jing;
Duan, Jia-Xi;
Zhang, Chen-Yu;
Jiang, Hui-Ling;
Xiang, Yang;
Zhou, Yong;
Guan, Cha-Xiang

Publication type:

Article

Up-regulation of microRNA-135 or silencing of PCSK6 attenuates inflammatory response in preeclampsia by restricting NLRP3 inflammasome.

Published in:

Molecular Medicine, 2021, v. 27, n. 1, p. 1, doi. 10.1186/s10020-021-00335-x

By:

Zhao, Xiaolan;
Zhang, Xun;
Wu, Zhao;
Mei, Jie;
Li, Lingling;
Wang, Yujue

Publication type:

Article

Resveratrol Alleviates Liver Fibrosis by Targeting Cross‐Talk Between TLR2/MyD88/ERK and NF‐κB/NLRP3 Inflammasome Pathways in Macrophages.

Published in:

Journal of Biochemical & Molecular Toxicology, 2025, v. 39, n. 3, p. 1, doi. 10.1002/jbt.70208

By:

Lei, Jin‐qing;
Xie, Qing‐li;
Li, Qing‐ping;
Qin, Shan‐yu;
Wu, Jiao‐hua;
Jiang, Hai‐xing;
Yu, Bing;
Luo, Wei

Publication type:

Article

Inhibition of NLRP3 inflammasome—A potential mechanistic therapeutic for treatment of polycystic ovary syndrome?

Published in:

Journal of Biochemical & Molecular Toxicology, 2024, v. 38, n. 1, p. 1, doi. 10.1002/jbt.23592

By:

Chamanara, Solmaz;
Hozouri, Vahid;
Irandoost, Elnaz

Publication type:

Article

Muscone attenuates susceptibility to ventricular arrhythmia by inhibiting NLRP3 inflammasome activation in rats after myocardial infarction.

Published in:

Journal of Biochemical & Molecular Toxicology, 2023, v. 37, n. 11, p. 1, doi. 10.1002/jbt.23458

By:

Yang, Shuang;
Bi, Yingying;
Wei, Yanzhao;
Li, Wei;
Liu, Jiangwen;
Mao, Tuohua;
Tang, Yanhong

Publication type:

Article

Gentiopicroside enhances the protective effect of trimetazidine against myocardial ischemia‐reperfusion injury via the AMPK/NLRP3 inflammasome signaling.

Published in:

Journal of Biochemical & Molecular Toxicology, 2023, v. 37, n. 7, p. 1, doi. 10.1002/jbt.23366

By:

Wang, Yu;
Sheng, Yao;
Ji, Ningning;
Zhang, Hui

Publication type:

Article

Sulforaphene targets NLRP3 inflammasome to suppress M1 polarization of macrophages and inflammatory response in rheumatoid arthritis.

Published in:

Journal of Biochemical & Molecular Toxicology, 2023, v. 37, n. 7, p. 1, doi. 10.1002/jbt.23362

By:

Ye, Qiao;
Yan, Tingting;
Shen, Jie;
Shi, Xianghui;
Luo, Fang;
Ren, Yanxia

Publication type:

Article

Dimethyl fumarate‐mediated Nrf2/ARE pathway activation and glibenclamide‐mediated NLRP3 inflammasome cascade inhibition alleviate type II diabetes‐associated fatty liver in rats by mitigating oxidative stress and inflammation.

Published in:

Journal of Biochemical & Molecular Toxicology, 2023, v. 37, n. 7, p. 1, doi. 10.1002/jbt.23357

By:

Dwivedi, Durgesh K.;
Jena, G. B.

Publication type:

Article

Proanthocyanidins suppress NLRP3 inflammasome and M1 macrophage polarization to alleviate severe acute pancreatitis in mice.

Published in:

Journal of Biochemical & Molecular Toxicology, 2023, v. 37, n. 2, p. 1, doi. 10.1002/jbt.23242

By:

Sheng, Li‐Ping;
Han, Chao‐Qun;
Ling, Xin;
Guo, Xian‐Wen;
Lin, Rong;
Ding, Zhen

Publication type:

Article

Galangin attenuates cadmium‐evoked nephrotoxicity: Targeting nucleotide‐binding domain‐like receptor pyrin domain containing 3 inflammasome, nuclear factor erythroid 2‐related factor 2, and nuclear factor kappa B signaling.

Published in:

Journal of Biochemical & Molecular Toxicology, 2022, v. 36, n. 7, p. 1, doi. 10.1002/jbt.23059

By:

Salama, Samir A.;
Abd‐Allah, Gamil M.;
Gad, Hesham S.;
Kabel, Ahmed M.

Publication type:

Article

Sodium houttuyfonate attenuates neurological defects after traumatic brain injury in mice via inhibiting NLRP3 inflammasomes.

Published in:

Journal of Biochemical & Molecular Toxicology, 2021, v. 35, n. 9, p. 1, doi. 10.1002/jbt.22850

By:

Yao, Xiaolong;
Wang, Shengbo;
Chen, Yingchun;
Sheng, Liuqing;
Li, Huanhuan;
You, Huichao;
Ye, Jianfeng;
Zhang, Qing;
Li, Jun

Publication type:

Article

Proanthocyanidins attenuate the high glucose‐induced damage of retinal pigment epithelial cells by attenuating oxidative stress and inhibiting activation of the NLRP3 inflammasome.

Published in:

Journal of Biochemical & Molecular Toxicology, 2021, v. 35, n. 9, p. 1, doi. 10.1002/jbt.22845

By:

Li, Hongsong;
Li, Rong;
Wang, Lijun;
Liao, Dingying;
Zhang, Wenyi;
Wang, Jianming

Publication type:

Article

AIM2 and NLRC4-driven inflammasome activation in adult-onset Still's disease and the preliminary therapeutic effect exploration of carboxyamidotriazole.

Published in:

Clinical Rheumatology, 2023, v. 42, n. 6, p. 1635, doi. 10.1007/s10067-022-06443-1

By:

Duan, Mengyuan;
Shen, Min;
Zhou, Yongting;
He, Yi;
Guo, Zehao;
Ye, Caiying;
Li, Juan;
Zhu, Lei

Publication type:

Article

Association of NLRP3 polymorphisms with susceptibility to primary gouty arthritis in a Chinese Han population.

Published in:

Clinical Rheumatology, 2018, v. 37, n. 1, p. 235, doi. 10.1007/s10067-017-3900-6

By:

Zhang, Quan-Bo;
Qing, Yu-Feng;
He, Yong-Long;
Xie, Wen-Guang;
Zhou, Jing-Guo

Publication type:

Article

Lights and shadows in autoinflammatory syndromes from the childhood and adulthood perspective.

Published in:

Clinical Rheumatology, 2016, v. 35, n. 3, p. 565, doi. 10.1007/s10067-015-3132-6

By:

Rigante, Donato;
Vitale, Antonio;
Natale, Marco;
Cantarini, Luca

Publication type:

Article

Bovine milk-derived exosomes attenuate NLRP3 inflammasome and NF-κB signaling in the lung during neonatal necrotizing enterocolitis.

Published in:

Pediatric Surgery International, 2023, v. 39, n. 1, p. 1, doi. 10.1007/s00383-023-05490-2

By:

Filler, Rachel;
Yeganeh, Mina;
Li, Bo;
Lee, Carol;
Alganabi, Mashriq;
Hock, Alison;
Biouss, George;
Balsamo, Felicia;
Lee, Dorothy;
Miyake, Hiromu;
Pierro, Agostino

Publication type:

Article

Activation of the NLRP3 and AIM2 inflammasomes in a mouse model of Schistosoma mansoni infection.

Published in:

Journal of Helminthology, 2020, v. 94, p. 1, doi. 10.1017/S0022149X19000622

By:

Chen, T.T.W.;
Cheng, P.C.;
Chang, K.C.;
Cao, J.P.;
Feng, J.L.;
Chen, C.C.;
Lam, H.Y.P.;
Peng, S.Y.

Publication type:

Article

The relationship between caspase-1 related inflammasome expression and serum inflammatory cytokine levels during acute brucellosis.

Published in:

Northern Clinics of Istanbul, 2019, v. 6, n. 2, p. 117, doi. 10.14744/nci.2018.96992

By:

Karaca, Gamze;
Karaca, Zeynal Mete;
Kayhan, Basak;
Bayindir, Yasar;
Kayabas, Uner;
Toplu, Sibel;
Elmasdag, Sirvan;
Onalan, Ebru;
Yesilada, Elif

Publication type:

Article

Peli1, regulated by m<sup>6</sup>A modification, suppresses NLRP3 inflammasome activation in atherosclerosis by inhibiting YB-1.

Published in:

Communications Biology, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42003-025-07839-w

By:

Liu, Qiang;
Yan, Lu;
Wu, Tao;
Wu, Qinghua;
Ke, Ben;
Shen, Wen

Publication type:

Article

Interferon signalling and non-canonical inflammasome activation promote host protection against multidrug-resistant Acinetobacter baumannii.

Published in:

Communications Biology, 2024, v. 7, n. 1, p. 1, doi. 10.1038/s42003-024-07204-3

By:

Li, Fei-Ju;
Starrs, Lora;
Mathur, Anukriti;
Enosi Tuipulotu, Daniel;
Man, Si Ming;
Burgio, Gaetan

Publication type:

Article

Uric acid-mediated inflammasome activation in IL-6 primed innate immune cells is regulated by baricitinib.

Published in:

Modern Rheumatology, 2021, v. 31, n. 1, p. 270, doi. 10.1080/14397595.2020.1740410

By:

Jumpei Temmoku;
Yuya Fujita;
Naoki Matsuoka;
Takeshi Urano;
Makiko Yashiro Furuya;
Tomoyuki Asano;
Shuzo Sato;
Haruki Matsumoto;
Hiroshi Watanabe;
Hideko Kozuru;
Hiroshi Yatsuhashi;
Atsushi Kawakami;
Kiyoshi Migita

Publication type:

Article

Biologic therapy in familial Mediterranean fever: Comment on the study by Koga et al.

Published in:

Modern Rheumatology, 2016, v. 26, n. 5, p. 805, doi. 10.1080/14397595.2016.1193107

By:

Toz, Bahtiyar;
Erer, Burak

Publication type:

Article

Broad-spectrum inflammasome inhibition by thiomuscimol.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-02238-2

By:

Anderson, Marisa J.;
den Hartigh, Andreas B.;
Loomis, Wendy P.;
Fink, Susan L.

Publication type:

Article

Pyroptosis leads to loss of centrosomal integrity in macrophages.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-02093-1

By:

Bai, Siyi;
Martin-Sanchez, Fatima;
Brough, David;
Lopez-Castejon, Gloria

Publication type:

Article

IRGM/Irgm1 increases autophagy to inhibit activation of NLRP3 inflammasome in inflammatory injury induced acute liver failure.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-02052-w

By:

Zhang, Xing;
Hu, Yangyang;
Wang, Wei;
Ji, Ru;
Li, Ziyue;
Yu, Weiyan;
Wu, Zhinian;
Xiao, Ying;
Guo, Tingyu;
Qi, Zeqiang;
Wang, Yadong;
Zhao, Caiyan

Publication type:

Article

Detection of inflammasome activation in liver tissue during the donation process as potential biomarker for liver transplantation.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-02042-y

By:

Mateo, Sandra V.;
Vidal-Correoso, Daniel;
Muñoz-Morales, Ana M.;
Jover-Aguilar, Marta;
Alconchel, Felipe;
de la Peña, Jesús;
Martínez-Alarcón, Laura;
López-López, Víctor;
Ríos-Zambudio, Antonio;
Cascales, Pedro;
Pons, José A.;
Ramírez, Pablo;
Pelegrín, Pablo;
Baroja-Mazo, Alberto

Publication type:

Article

Renal macrophages and NLRP3 inflammasomes in kidney diseases and therapeutics.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-01996-3

By:

Islamuddin, Mohammad;
Qin, Xuebin

Publication type:

Article

SARS-CoV-2 and its ORF3a, E and M viroporins activate inflammasome in human macrophages and induce of IL-1α in pulmonary epithelial and endothelial cells.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-01966-9

By:

Ambrożek-Latecka, Magdalena;
Kozlowski, Piotr;
Hoser, Grażyna;
Bandyszewska, Magdalena;
Hanusek, Karolina;
Nowis, Dominika;
Gołąb, Jakub;
Grzanka, Małgorzata;
Piekiełko-Witkowska, Agnieszka;
Schulz, Luise;
Hornung, Franziska;
Deinhardt-Emmer, Stefanie;
Kozlowska, Ewa;
Skirecki, Tomasz

Publication type:

Article

The mechanism underlying correlation of particulate matter-induced ferroptosis with inflammasome activation and iron accumulation in macrophages.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-01874-y

By:

Park, Minkyung;
Park, Sujeong;
Choi, Yumin;
Cho, Young-Lai;
Kim, Min Jeong;
Park, Young-Jun;
Chung, Su Wol;
Lee, Heedoo;
Lee, Seon-Jin

Publication type:

Article

Uric acid–driven NLRP3 inflammasome activation triggers lens epithelial cell senescence and cataract formation.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-01900-z

By:

Lin, Hong Liang;
Wang, Sheng;
Sato, Kota;
Zhang, Yu Qiao;
He, Bei Ting;
Xu, Jing;
Nakazawa, Toru;
Qin, Yong Jie;
Zhang, Hong Yang

Publication type:

Article

From Innate Immunity to Metabolic Disorder: A Review of the NLRP3 Inflammasome in Diabetes Mellitus.

Published in:

Journal of Clinical Medicine, 2023, v. 12, n. 18, p. 6022, doi. 10.3390/jcm12186022

By:

Nițulescu, Iris Maria;
Ciulei, George;
Cozma, Angela;
Procopciuc, Lucia Maria;
Orășan, Olga Hilda

Publication type:

Article

From Bench to Bedside in Rheumatoid Arthritis from the "2022 GISEA International Symposium".

Published in:

Journal of Clinical Medicine, 2023, v. 12, n. 2, p. 527, doi. 10.3390/jcm12020527

By:

Vitale, Antonio;
Alivernini, Stefano;
Caporali, Roberto;
Cassone, Giulia;
Bruno, Dario;
Cantarini, Luca;
Lopalco, Giuseppe;
Rossini, Maurizio;
Atzeni, Fabiola;
Favalli, Ennio Giulio;
Conti, Fabrizio;
Gremese, Elisa;
Iannone, Florenzo;
Ferraccioli, Gian Franco;
Lapadula, Giovanni;
Sebastiani, Marco

Publication type:

Article

DJ-1 Alleviates Neuroinflammation and the Related Blood-Spinal Cord Barrier Destruction by Suppressing NLRP3 Inflammasome Activation via SOCS1/Rac1/ROS Pathway in a Rat Model of Traumatic Spinal Cord Injury.

Published in:

Journal of Clinical Medicine, 2022, v. 11, n. 13, p. 3716, doi. 10.3390/jcm11133716

By:

Cai, Lingxin;
Gao, Liansheng;
Zhang, Guoqiang;
Zeng, Hanhai;
Wu, Xinyan;
Tan, Xiaoxiao;
Qian, Cong;
Chen, Gao

Publication type:

Article