Works matching AU Hanahan, Douglas

Results: 38

Assessing Tumor Progression Factors by Somatic Gene Transfer into a Mouse Model: Bcl-xL Promotes Islet Tumor Cell Invasion.

Published in:

PLoS Biology, 2007, v. 5, n. 10, p. e276, doi. 10.1371/journal.pbio.0050276

By:

Yi-Chieh Nancy Du;
Lewis, Brian C.;
Hanahan, Douglas;
Varmus, Harold

Publication type:

Article

Multiple Roles for Cysteine Cathepsins in Cancer.

Published in:

Cell Cycle, 2004, v. 3, n. 12, p. 1516, doi. 10.4161/cc.3.12.1289

By:

Joyce, Johanna A.;
Hanahan, Douglas

Publication type:

Article

Towards a Cancer Mission in Horizon Europe.

Published in:

Molecular Oncology, 2019, v. 13, n. 11, p. 2301, doi. 10.1002/1878-0261.12585

By:

Berns, Anton;
Ringborg, Ulrik;
Eggermont, Alexander;
Baumann, Michael;
Calvo, Fabien;
Eggert, Angelika;
Espina, Carolina;
Hanahan, Douglas;
Lacombe, Denis;
Lorenzo, Francesco;
Oberst, Simon;
Philip, Thierry;
Schüz, Joachim;
Tabernero, Josep;
Celis, Julio E.

Publication type:

Article

The biology of personalized cancer medicine: Facing individual complexities underlying hallmark capabilities

Published in:

Molecular Oncology, 2012, v. 6, n. 2, p. 111, doi. 10.1016/j.molonc.2012.01.011

By:

De Palma, Michele;
Hanahan, Douglas

Publication type:

Article

Procathepsin E is highly abundant but minimally active in pancreatic ductal adenocarcinoma tumors.

Published in:

Biological Chemistry, 2016, v. 397, n. 9, p. 871, doi. 10.1515/hsz-2016-0138

By:

O'Donoghue, Anthony J.;
Ivry, Sam L.;
Chaudhury, Chaity;
Hostetter, Daniel R.;
Hanahan, Douglas;
Craik, Charles S.

Publication type:

Article

Functions of Paracrine PDGF Signaling in the Proangiogenic Tumor Stroma Revealed by Pharmacological Targeting.

Published in:

PLoS Medicine, 2008, v. 5, n. 1, p. e19, doi. 10.1371/journal.pmed.0050019

By:

Pietras, Kristian;
Pahler, Jessica;
Bergers, Gabriele;
Hanahan, Douglas

Publication type:

Article

Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis.

Published in:

Nature Cell Biology, 2000, v. 2, n. 10, p. 737, doi. 10.1038/35036374

By:

Bergers, Gabriele;
Brekken, Rolf;
McMahon, Gerald;
Vu, Thiennu H.;
Itoh, Takeshi;
Tamaki, Kazuhiko;
Tanzawa, Kazuhiko;
Thorpe, Philip;
Itohara, Shigeyoshi;
Werb, Zena;
Hanahan, Douglas

Publication type:

Article

Proglucagon processing similar to normal islets in pancreatic alpha-like cell line derived from transgenic mouse tumor.

Published in:

1990

By:

Powers, Alvin C.;
Efrat, Shimon;
Mojsov, Svetlana;
Spector, David;
Habener, Joel F.;
Hanahan, Douglas;
Powers, A C;
Efrat, S;
Mojsov, S;
Spector, D;
Habener, J F;
Hanahan, D

Publication type:

journal article

Translational medicine: Cancer lessons from mice to humans.

Published in:

Nature, 2011, v. 471, n. 7338, p. 316, doi. 10.1038/471316a

By:

Tuveson, David;
Hanahan, Douglas

Publication type:

Article

Genome scanning with array CGH delineates regional alterations in mouse islet carcinomas.

Published in:

Nature Genetics, 2001, v. 29, n. 4, p. 459, doi. 10.1038/ng771

By:

Hodgson, Graeme;
Hager, Jeffrey H.;
Volik, Stas;
Hariono, Sujatmi;
Wernick, Meredith;
Moore, Dan;
Albertson, Donna G.;
Pinkel, Daniel;
Collins, Colin;
Hanahan, Douglas;
Gray, Joe W.

Publication type:

Article

Modes of resistance to anti-angiogenic therapy.

Published in:

2008

By:

Bergers, Gabriele;
Hanahan, Douglas

Publication type:

journal article

Reply to Colorectal cancer classification based on gene expression is not associated with FOLFIRI response.

Published in:

Nature Medicine, 2014, v. 20, n. 11, p. 1231, doi. 10.1038/nm.3742

By:

Sadanandam, Anguraj;
Gray, Joe;
Hanahan, Douglas

Publication type:

Article

A colorectal cancer classification system that associates cellular phenotype and responses to therapy.

Published in:

Nature Medicine, 2013, v. 19, n. 5, p. 619, doi. 10.1038/nm.3175

By:

Sadanandam, Anguraj;
Lyssiotis, Costas A;
Homicsko, Krisztian;
Collisson, Eric A;
Gibb, William J;
Wullschleger, Stephan;
Ostos, Liliane C Gonzalez;
Lannon, William A;
Grotzinger, Carsten;
Del Rio, Maguy;
Lhermitte, Benoit;
Olshen, Adam B;
Wiedenmann, Bertram;
Cantley, Lewis C;
Gray, Joe W;
Hanahan, Douglas

Publication type:

Article

Subtypes of pancreatic ductal adenocarcinoma and their differing responses to therapy.

Published in:

Nature Medicine, 2011, v. 17, n. 4, p. 500, doi. 10.1038/nm.2344

By:

Collisson, Eric A.;
Sadanandam, Anguraj;
Olson, Peter;
Gibb, William J.;
Truitt, Morgan;
Gu, Shenda;
Cooc, Janine;
Weinkle, Jennifer;
Kim, Grace E.;
Jakkula, Lakshmi;
Feiler, Heidi S.;
Ko, Andrew H.;
Olshen, Adam B.;
Danenberg, Kathleen L.;
Tempero, Margaret A.;
Spellman, Paul T.;
Hanahan, Douglas;
Gray, Joe W.

Publication type:

Article

Sub-lethal radiation enhances anti-tumor immunotherapy in a transgenic mouse model of pancreatic cancer.

Published in:

BMC Cancer, 2002, v. 2, p. 11, doi. 10.1186/1471-2407-2-11

By:

Cao, Zhu Alexander;
Daniel, Dylan;
Hanahan, Douglas

Publication type:

Article

Tumor Cells Utilize Multiple Pathways to Down-modulate Apoptosis: Lessons from a Mouse Model of Islet Cell Carcinogenesis.

Published in:

Annals of the New York Academy of Sciences, 1999, v. 887, n. 1, p. 150, doi. 10.1111/j.1749-6632.1999.tb07929.x

By:

HAGER, JEFFREY H.;
HANAHAN, DOUGLAS

Publication type:

Article

Heritable formation of pancreatic β-cell tumours in transgenic mice expressing recombinant insulin/simian virus 40 oncogenes.

Published in:

Nature, 1985, v. 315, n. 6015, p. 115, doi. 10.1038/315115a0

By:

Hanahan, Douglas

Publication type:

Article

Tumour development: Oncogenes in transgenic mice.

Published in:

Nature, 1984, v. 312, n. 5994, p. 503, doi. 10.1038/312503a0

By:

Hanahan, Douglas

Publication type:

Article

Structure of the pro α2(I) collagen gene.

Published in:

Nature, 1981, v. 294, n. 5837, p. 129, doi. 10.1038/294129a0

By:

Wozney, John;
Hanahan, Douglas;
Tate, Valerie;
Boedtker, Helga;
Doty, Paul

Publication type:

Article

Tumor lymphangiogenesis promotes T cell infiltration and potentiates immunotherapy in melanoma.

Published in:

Science Translational Medicine, 2017, v. 9, n. 407, p. 1, doi. 10.1126/scitranslmed.aal4712

By:

Fankhauser, Manuel;
Broggi, Maria A. S.;
Potin, Lambert;
Bordry, Natacha;
Jeanbart, Laura;
Lund, Amanda W.;
Da Costa, Elodie;
Hauert, Sylvie;
Rincon-Restrepo, Marcela;
Tremblay, Christopher;
Cabello, Elena;
Homicsko, Krisztian;
Michielin, Olivier;
Hanahan, Douglas;
Speiser, Daniel E.;
Swartz, Melody A.

Publication type:

Article

Combined antiangiogenic and anti-PD-L1 therapy stimulates tumor immunity through HEV formation.

Published in:

Science Translational Medicine, 2017, v. 9, n. 385, p. 1, doi. 10.1126/scitranslmed.aak9679

By:

Allen, Elizabeth;
Jabouille, Arnaud;
Rivera, Lee B.;
Lodewijckx, Inge;
Missiaen, Rindert;
Steri, Veronica;
Feyen, Kevin;
Tawney, Jaime;
Hanahan, Douglas;
Michael, Iacovos P.;
Bergers, Gabriele

Publication type:

Article

DNA copy number changes associated with characteristic LOH in islet cell carcinomas of transgenic mice.

Published in:

Genes, Chromosomes & Cancer, 1997, v. 19, n. 2, p. 104, doi. 10.1002/(SICI)1098-2264(199706)19:2<104::AID-GCC6>3.0.CO;2-2

By:

Shi, Yu Ping;
Naik, Paul;
Dietrich, William F.;
Gray, Joe W.;
Hanahan, Douglas;
Pinkel, Daniel

Publication type:

Article

Benefits of bad telomeres.

Published in:

Nature, 2000, v. 406, n. 6796, p. 573, doi. 10.1038/35020662

By:

Hanahan, Douglas

Publication type:

Article

Pancreatic gene expression in rare cells of thymic medulla: evidence for functional contribution to T cell tolerance.

Published in:

International Immunology, 1997, v. 9, n. 9, p. 1355, doi. 10.1093/intimm/9.9.1355

By:

Smith, Kathleen M.;
Olson, David C.;
Ryutaro Hirose;
Hanahan, Douglas

Publication type:

Article

Deficiency for the Cysteine Protease Cathepsin L Impairs Myc-Induced Tumorigenesis in a Mouse Model of Pancreatic Neuroendocrine Cancer.

Published in:

PLoS ONE, 2015, v. 10, n. 4, p. 1, doi. 10.1371/journal.pone.0120348

By:

Brindle, Nicola R.;
Joyce, Johanna A.;
Rostker, Fanya;
Lawlor, Elizabeth R.;
Swigart-Brown, Lamorna;
Evan, Gerard;
Hanahan, Douglas;
Shchors, Ksenya

Publication type:

Article

Identification and Characterization of Poorly Differentiated Invasive Carcinomas in a Mouse Model of Pancreatic Neuroendocrine Tumorigenesis

Published in:

PLoS ONE, 2013, v. 8, n. 5, p. 1, doi. 10.1371/journal.pone.0064472

By:

Hunter, Karen E.;
Quick, Marsha L.;
Sadanandam, Anguraj;
Hanahan, Douglas;
Joyce, Johanna A.

Publication type:

Article

Loss of p19<sup>Arf</sup> Facilitates the Angiogenic Switch and Tumor Initiation in a Multi-Stage Cancer Model via p53-Dependent and Independent Mechanisms.

Published in:

PLoS ONE, 2010, v. 5, n. 8, p. 1, doi. 10.1371/journal.pone.0012454

By:

Ulanet, Danielle B.;
Hanahan, Douglas

Publication type:

Article

Genetic Ablation of Bcl-x Attenuates Invasiveness without Affecting Apoptosis or Tumor Growth in a Mouse Model of Pancreatic Neuroendocrine Cancer.

Published in:

PLoS ONE, 2009, v. 4, n. 2, p. 1, doi. 10.1371/journal.pone.0004455

By:

Hager, Jeffrey H.;
Ulanet, Danielle B.;
Hennighausen, Lothar;
Hanahan, Douglas

Publication type:

Article

Isolation of the chicken thymidine kinase gene by plasmid rescue.

Published in:

Nature, 1980, v. 285, n. 5762, p. 207, doi. 10.1038/285207a0

By:

Perucho, Manuel;
Hanahan, Douglas;
Lipsich, Leah;
Wigler, Michael

Publication type:

Article

Incomplete inhibition of the Rb tumor suppressor pathway in the context of inactivated p53 is sufficient for pancreatic islet tumorigenesis.

Published in:

Oncogene, 2005, v. 24, n. 44, p. 6597, doi. 10.1038/sj.onc.1208823

By:

Casanovas, Oriol;
Hager, Jeffrey H.;
Matthew Gee Hong Chun;
Hanahan, Douglas

Publication type:

Article

A functional heparan sulfate mimetic implicates both heparanase and heparan sulfate in tumor angiogenesis and invasion in a mouse model of multistage cancer.

Published in:

Oncogene, 2005, v. 24, n. 25, p. 4037, doi. 10.1038/sj.onc.1208602

By:

Joyce, Johanna A.;
Freeman, Craig;
Meyer-Morse, Nicole;
Parish, Christopher R.;
Hanahan, Douglas

Publication type:

Article

A functional heparan sulfate mimetic implicates both heparanase and heparan sulfate in tumor angiogenesis and invasion in a mouse model of multistage cancer.

Published in:

2005

By:

Joyce, Johanna A;
Freeman, Craig;
Meyer-Morse, Nicole;
Parish, Christopher R;
Hanahan, Douglas

Publication type:

Correction Notice

Cell factories for fighting cancer.

Published in:

Nature Biotechnology, 2001, v. 19, n. 1, p. 20, doi. 10.1038/83457

By:

Bergers, Gabriele;
Hanahan, Douglas

Publication type:

Article

Of Mice and MEN1: Insulinomas in Conditional Mouse Knockout.

Published in:

Molecular & Cellular Biology, 2003, v. 23, n. 17, p. 6075, doi. 10.1128/MCB.23.17.6075-6085.2003

By:

Crabtree, Judy S.;
Scacheri, Peter C.;
Ward, Jerrold M.;
McNally, Sara R.;
Swain, Gary P.;
Montagna, Cristina;
Hager, Jeffrey H.;
Hanahan, Douglas;
Edlund, Helena;
Magnuson, Mark A.;
Garrett-Beal, Lisa;
Burns, A. Lee;
Ried, Thomas;
Chandrasekharappa, Settara C.;
Marx, Stephen J.;
Spiegel, Allen M.;
Collins, Francis S.

Publication type:

Article

Non-tolerance and autoantibodies to a transgenic self antigen expressed in pancreatic β cells.

Published in:

Nature, 1987, v. 325, n. 6101, p. 223, doi. 10.1038/325223a0

By:

Adams, Timothy E.;
Alpert, Susan;
Hanahan, Douglas

Publication type:

Article

Bovine papillomavirus genome elicits skin tumours in transgenic mice.

Published in:

Nature, 1986, v. 322, n. 6080, p. 609, doi. 10.1038/322609a0

By:

Lacey, Mark;
Alpert, Susan;
Hanahan, Douglas

Publication type:

Article

Reconciliation of classification systems defining molecular subtypes of colorectal cancer.

Published in:

Cell Cycle, 2014, v. 13, n. 3, p. 353, doi. 10.4161/cc.27769

By:

Sadanandam, Anguraj;
Xin Wang;
de Sousa E. Melo, Felipe;
Gray, Joe W.;
Vermeulen, Louis;
Hanahan, Douglas;
Medema, Jan Paul

Publication type:

Article

An amino-bisphosphonate targets MMP-9--expressing macrophages and angiogenesis to impair cervical carcinogenesis.

Published in:

Journal of Clinical Investigation, 2004, v. 114, n. 5, p. 623, doi. 10.1172/JCI200422087

By:

Giraudo, Enrico;
Inoue, Masahiro;
Hanahan, Douglas

Publication type:

Article