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A Structural Proteomics Exploration of Synphilin-1 and Alpha-Synuclein Interaction in Pathogenesis of Parkinson's Disease.
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- Biomolecules (2218-273X), 2024, v. 14, n. 12, p. 1588, doi. 10.3390/biom14121588
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- Article
Human and Tree Shrew Alpha-synuclein: Comparative cDNA Sequence and Protein Structure Analysis.
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- Applied Biochemistry & Biotechnology, 2015, v. 177, n. 4, p. 957, doi. 10.1007/s12010-015-1789-6
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- Article
A pyrene-inhibitor fluorescent probe with large Stokes shift for the staining of Aβ<sub>1-42</sub>, α-synuclein, and amylin amyloid fibrils as well as amyloid-containing Staphylococcus aureus biofilms.
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- Analytical & Bioanalytical Chemistry, 2019, v. 411, n. 1, p. 251, doi. 10.1007/s00216-018-1433-8
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- Article
Modulation of the Conformational Space of SARS‐CoV‐2 RNA Quadruplex RG‐1 by Cellular Components and the Amyloidogenic Peptides α‐Synuclein and hIAPP.
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- Chemistry - A European Journal, 2022, v. 28, n. 9, p. 1, doi. 10.1002/chem.202104182
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- Article
Alpha‐Synuclein Modulates the Physical Properties of DNA.
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- Chemistry - A European Journal, 2018, v. 24, n. 58, p. 15685, doi. 10.1002/chem.201803933
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- Article
A Hydroxylamine‐Mediated Amidination of Lysine Residues That Retains the Protein's Positive Charge.
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- Angewandte Chemie, 2024, v. 136, n. 31, p. 1, doi. 10.1002/ange.202402880
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- Article
Taylor Dispersion‐Induced Phase Separation for the Efficient Characterisation of Protein Condensate Formation.
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- Angewandte Chemie, 2024, v. 136, n. 25, p. 1, doi. 10.1002/ange.202404018
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- Article
Single‐Molecule Two‐Color Coincidence Detection of Unlabeled alpha‐Synuclein Aggregates.
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- Angewandte Chemie, 2023, v. 135, n. 15, p. 1, doi. 10.1002/ange.202216771
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- Article
Decreased Water Mobility Contributes To Increased α‐Synuclein Aggregation**.
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- Angewandte Chemie, 2023, v. 135, n. 7, p. 1, doi. 10.1002/ange.202212063
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- Article
α‐Synuclein as a Target for Metallo‐Anti‐Neurodegenerative Agents.
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- Angewandte Chemie, 2023, v. 135, n. 1, p. 1, doi. 10.1002/ange.202215360
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- Article
Direct Observation of "Elongated" Conformational States in α‐Synuclein upon Liquid‐Liquid Phase Separation.
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- Angewandte Chemie, 2022, v. 134, n. 46, p. 1, doi. 10.1002/ange.202205726
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- Article
Tailoring a Nanochaperone to Regulate α‐Synuclein Assembly.
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- Angewandte Chemie, 2022, v. 134, n. 19, p. 1, doi. 10.1002/ange.202200192
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- Article
The link between the gut microbiome, inflammation, and Parkinson's disease.
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- Applied Microbiology & Biotechnology, 2023, v. 107, n. 22, p. 6737, doi. 10.1007/s00253-023-12789-6
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- Article
The alteration of intestinal mucosal α-synuclein expression and mucosal microbiota in Parkinson's disease.
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- Applied Microbiology & Biotechnology, 2023, v. 107, n. 5/6, p. 1917, doi. 10.1007/s00253-023-12410-w
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- Article
Complex modulation of cytokine-induced α-synuclein aggregation by glypican-1-derived heparan sulfate in neural cells.
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- Glycobiology, 2022, v. 32, n. 4, p. 333, doi. 10.1093/glycob/cwab126
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- Article
Dose-Dependent Alterations of Lysosomal Activity and Alpha-Synuclein in Peripheral Blood Monocyte-Derived Macrophages and SH-SY5Y Neuroblastoma Cell Line by upon Inhibition of MTOR Protein Kinase – Assessment of the Prospects of Parkinson's Disease Therapy
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- Biochemistry (00062979), 2024, v. 89, n. 7, p. 1300, doi. 10.1134/S0006297924070113
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- Article
Role of the Gut Microbiome and Bacterial Amyloids in the Development of Synucleinopathies.
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- Biochemistry (00062979), 2024, v. 89, n. 3, p. 523, doi. 10.1134/S0006297924030118
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- Article
Skeletal Muscle is a Source of α-Synuclein with a Sarcolemmal Non-Lipid Raft Distribution.
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- Cellular Physiology & Biochemistry (Cell Physiol Biochem Press GmbH & Co. KG), 2022, v. 56, n. 4, p. 382, doi. 10.33594/000000558
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- Article
Alpha-synuclein is strategically positioned for afferent modulation of midbrain dopamine neurons and is essential for cocaine preference.
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- Communications Biology, 2019, v. 2, n. 1, p. N.PAG, doi. 10.1038/s42003-019-0651-8
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- Article
Alpha-synuclein stepwise aggregation reveals features of an early onset mutation in Parkinson's disease.
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- Communications Biology, 2019, v. 2, n. 1, p. N.PAG, doi. 10.1038/s42003-019-0598-9
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- Article
2D polarization imaging as a low-cost fluorescence method to detect α-synuclein aggregation ex vivo in models of Parkinson's disease.
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- Communications Biology, 2018, v. 1, n. 1, p. N.PAG, doi. 10.1038/s42003-018-0156-x
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Author Correction: Efficacy and immunogenicity of MultiTEP-based DNA vaccines targeting human α-synuclein: prelude for IND enabling studies.
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- 2023
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- Correction Notice
AAV-mediated expression of a new conformational anti-aggregated α-synuclein antibody prolongs survival in a genetic model of α-synucleinopathies.
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- NPJ Parkinson's Disease, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41531-023-00542-9
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- Article
Combining skin and olfactory α-synuclein seed amplification assays (SAA)—towards biomarker-driven phenotyping in synucleinopathies.
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- NPJ Parkinson's Disease, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41531-023-00519-8
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- Article
Glucocerebrosidase activity and lipid levels are related to protein pathologies in Parkinson's disease.
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- NPJ Parkinson's Disease, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41531-023-00517-w
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- Article
Periaqueductal grey and spinal cord pathology contribute to pain in Parkinson's disease.
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- NPJ Parkinson's Disease, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41531-023-00510-3
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- Article
Neuroprotective actions of a fatty acid nitroalkene in Parkinson's disease.
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- NPJ Parkinson's Disease, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41531-023-00502-3
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- Article
The small GTPase Rit2 modulates LRRK2 kinase activity, is required for lysosomal function and protects against alpha-synuclein neuropathology.
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- NPJ Parkinson's Disease, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41531-023-00484-2
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- Article
Distribution of phosphorylated alpha-synuclein in non-diseased brain implicates olfactory bulb mitral cells in synucleinopathy pathogenesis.
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- NPJ Parkinson's Disease, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41531-023-00491-3
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- Article
MAPKAPK2, a potential dynamic network biomarker of α-synuclein prior to its aggregation in PD patients.
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- NPJ Parkinson's Disease, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41531-023-00479-z
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- Article
Inflammatory CSF profiles and longitudinal development of cognitive decline in sporadic and GBA-associated PD.
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- NPJ Parkinson's Disease, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41531-023-00476-2
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- Article
A comparative blind study between skin biopsy and seed amplification assay to disclose pathological α-synuclein in RBD.
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- NPJ Parkinson's Disease, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41531-023-00473-5
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- Article
Patients with isolated REM-sleep behavior disorder have elevated levels of alpha-synuclein aggregates in stool.
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- NPJ Parkinson's Disease, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41531-023-00458-4
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- Article
Dynamic physiological α-synuclein S129 phosphorylation is driven by neuronal activity.
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- NPJ Parkinson's Disease, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41531-023-00444-w
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- Article
C/EBPβ/AEP is age-dependently activated in Parkinson's disease and mediates α-synuclein in the gut and brain.
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- NPJ Parkinson's Disease, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41531-022-00430-8
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- Article
Diffusion along perivascular spaces as marker for impairment of glymphatic system in Parkinson's disease.
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- NPJ Parkinson's Disease, 2022, v. 8, n. 1, p. 1, doi. 10.1038/s41531-022-00437-1
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- Article
Optical pulse labeling studies reveal exogenous seeding slows α-synuclein clearance.
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- NPJ Parkinson's Disease, 2022, v. 8, n. 1, p. 1, doi. 10.1038/s41531-022-00434-4
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- Article
Revisiting the specificity and ability of phospho-S129 antibodies to capture alpha-synuclein biochemical and pathological diversity.
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- NPJ Parkinson's Disease, 2022, v. 8, n. 1, p. 1, doi. 10.1038/s41531-022-00388-7
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- Article
Parkinson-causing mutations in LRRK2 impair the physiological tetramerization of endogenous α-synuclein in human neurons.
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- NPJ Parkinson's Disease, 2022, v. 8, n. 1, p. 1, doi. 10.1038/s41531-022-00380-1
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- Article
Linking the phenotype of SNCA Triplication with PET-MRI imaging pattern and alpha-synuclein CSF seeding.
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- NPJ Parkinson's Disease, 2022, v. 8, n. 1, p. 1, doi. 10.1038/s41531-022-00379-8
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- Article
Lysosomal lipid alterations caused by glucocerebrosidase deficiency promote lysosomal dysfunction, chaperone-mediated-autophagy deficiency, and alpha-synuclein pathology.
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- NPJ Parkinson's Disease, 2022, v. 8, n. 1, p. 1, doi. 10.1038/s41531-022-00397-6
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- Article
Long-term inhibition of mutant LRRK2 hyper-kinase activity reduced mouse brain α-synuclein oligomers without adverse effects.
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- NPJ Parkinson's Disease, 2022, v. 8, n. 1, p. 1, doi. 10.1038/s41531-022-00386-9
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- Article
Harmol promotes α-synuclein degradation and improves motor impairment in Parkinson's models via regulating autophagy-lysosome pathway.
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- NPJ Parkinson's Disease, 2022, v. 8, n. 1, p. 1, doi. 10.1038/s41531-022-00361-4
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- Article
Opportunities and challenges of alpha-synuclein as a potential biomarker for Parkinson's disease and other synucleinopathies.
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- NPJ Parkinson's Disease, 2022, v. 8, n. 1, p. 1, doi. 10.1038/s41531-022-00357-0
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- Article
Beta2-adrenoreceptor agonist clenbuterol produces transient decreases in alpha-synuclein mRNA but no long-term reduction in protein.
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- NPJ Parkinson's Disease, 2022, v. 8, n. 1, p. 1, doi. 10.1038/s41531-022-00322-x
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- Article
Effects of Alzheimer's genetic risk scores and CSF biomarkers in de novo Parkinson's Disease.
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- NPJ Parkinson's Disease, 2022, v. 8, n. 1, p. 1, doi. 10.1038/s41531-022-00317-8
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- Article
Similarities and differences between nigral and enteric dopaminergic neurons unravel distinctive involvement in Parkinson's disease.
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- NPJ Parkinson's Disease, 2022, v. 8, n. 1, p. 1, doi. 10.1038/s41531-022-00308-9
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- Article
Similar neuronal imprint and no cross-seeded fibrils in α-synuclein aggregates from MSA and Parkinson's disease.
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- NPJ Parkinson's Disease, 2022, v. 8, n. 1, p. 1, doi. 10.1038/s41531-021-00264-w
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- Article
The Mediating Role of Inflammation in the Relationship Between α-Synuclein and Cognitive Functioning.
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- Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2023, v. 78, n. 2, p. 206, doi. 10.1093/gerona/glac217
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- Article
A Novel C-Type Lectin Receptor-Targeted α-Synuclein-Based Parkinson Vaccine Induces Potent Immune Responses and Therapeutic Efficacy in Mice.
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- Vaccines, 2022, v. 10, n. 9, p. 1432, doi. 10.3390/vaccines10091432
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- Article