Prolonged sertraline use related carcinoembryonic antigen increase.

Ceylan, Mehmet; �nsalver, Baris; Evrensel, Alper; Kaya Yertutanol, Fatma; Dönmez, Aslihan

Even though the exact mechanism of the increase in tumor markers is not precise in our patients, it might be suggested that SSRI use is asked in all patients with increased CEA before proceeding with further detailed malignancy investigations. We have previously reported an increase in carcinoembryonic antigen (CEA) in two patients on paroxetine and escitalopram.[[1]],[[2]] Here, we report the third case with mildly elevated CA 15-3 and CEA tumor markers related to prolonged sertraline use. Sir, Selective serotonin reuptake inhibitors (SSRI) are used worldwide for various neuropsychiatric disorders and other medical diagnoses such as chronic pain and irritable bowel syndrome with few drug-related complications for more than 30 years.

CARCINOEMBRYONIC antigen; SERTRALINE; SEROTONIN uptake inhibitors

Indian Journal of Pharmacology, 2021, Vol 53, Issue 4, p334

0253-7613

Academic Journal

10.4103/ijp.ijp_370_21