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- Title
Mitochondrial Neurogastrointestinal Encephalomyopathy: A Nonrenal Indication for Peritoneal Dialysis.
- Authors
Chandra, V. S.; Lakshmi, B. Sanggetha; Devi, S. V. V. Padmavathi; Praveen, N.; Sameera, N. S.; Reddy, A. S.; Ram, R.; Kumar, V. S.
- Abstract
Mitochondrial neurogastrointestinal encephalomyopathy is a rare autosomal recessive disorder characterized by severe muscle wasting, gastrointestinal dysmotility, leukoencephalopathy, peripheral neuropathy, and ophthalmoplegia. The pathogenesis involves the accumulation of very high concentrations of nucleosides dThd and dUrd along with depletion of nucleotide dCTP. One of the treatment measures is the removal of nucleosides dThd and dUrd by hemodialysis and peritoneal dialysis. Only a few patient reports of dialysis as a measure to remove nucleosides had been reported.
- Subjects
PERITONEAL dialysis; DEOXYRIBONUCLEOSIDES; MITOCHONDRIAL encephalomyopathies
- Publication
Indian Journal of Nephrology, 2018, Vol 28, Issue 4, p310
- ISSN
0971-4065
- Publication type
Academic Journal
- DOI
10.4103/ijn.IJN_404_17