Title: Mitochondrial Neurogastrointestinal Encephalomyopathy: A Nonrenal Indication for Peritoneal Dialysis.
Authors: Chandra, V. S.; Lakshmi, B. Sanggetha; Devi, S. V. V. Padmavathi; Praveen, N.; Sameera, N. S.; Reddy, A. S.; Ram, R.; Kumar, V. S.
Abstract: Mitochondrial neurogastrointestinal encephalomyopathy is a rare autosomal recessive disorder characterized by severe muscle wasting, gastrointestinal dysmotility, leukoencephalopathy, peripheral neuropathy, and ophthalmoplegia. The pathogenesis involves the accumulation of very high concentrations of nucleosides dThd and dUrd along with depletion of nucleotide dCTP. One of the treatment measures is the removal of nucleosides dThd and dUrd by hemodialysis and peritoneal dialysis. Only a few patient reports of dialysis as a measure to remove nucleosides had been reported.
Subjects: PERITONEAL dialysis; DEOXYRIBONUCLEOSIDES; MITOCHONDRIAL encephalomyopathies
Publication: Indian Journal of Nephrology, 2018, Vol 28, Issue 4, p310
ISSN: 0971-4065
Publication type: Academic Journal
DOI: 10.4103/ijn.IJN_404_17

Mitochondrial Neurogastrointestinal Encephalomyopathy: A Nonrenal Indication for Peritoneal Dialysis.

Chandra, V. S.; Lakshmi, B. Sanggetha; Devi, S. V. V. Padmavathi; Praveen, N.; Sameera, N. S.; Reddy, A. S.; Ram, R.; Kumar, V. S.