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- Title
Comparison of efficacy of 0.75% ropivacaine and 2% lidocaine with 1:200,000 adrenaline in pain control in extraction of mandibular posterior teeth: A double-blind study.
- Authors
Ranjan, Rishab; Kumar, S. N. Santhosh; Singh, Manju; Santhosh Kumar, S N
- Abstract
<bold>Background: </bold>Two percent lidocaine hydrochloride is the gold standard for dental anesthesia against which newer local anesthetic agents may be compared. 0.75% ropivacaine is a newer, long-acting amide local anesthetic agent with inherent vasoconstriction property.<bold>Aim: </bold>This study aims to compare the efficacy of 0.75% ropivacaine and 2% lidocaine hydrochloride with 1:200,000 adrenaline in pain control in extraction of mandibular posterior teeth.<bold>Settings and Design: </bold>This is a prospective, double-blind, and split-mouth study.<bold>Subjects and Methods: </bold>Twenty patients were divided into two groups according to the right and left sides of patient - side A and side B. The side, where 0.75% ropivacaine was to be administered, was randomly selected by flip coin method. Then, the pterygomandibular and long buccal nerve blocks were administered with 0.75% ropivacaine and necessary dental extraction was performed. After 1 week, the same procedure was repeated using 2% lidocaine hydrochloride with 1:200,000 adrenaline. The parameters assessed were pain on injection, onset of anesthesia, pain during the extraction, and duration of anesthesia.<bold>Statistical Analysis Used: </bold>The nonparametric data were assessed by Mann Whitney "U" test.<bold>Results: </bold>The mean onset of action for solution A was 7.15 ± 4.934 min and for solution B was 9.75±5.128 min. This was statistically significant. The mean duration of action, pain on injection, and pain during extraction were not significant.<bold>Conclusion: </bold>This study clearly states that there is no clear advantage of using 0.75% ropivacaine in pterygomandibular nerve block over the gold standard. However, more clinical studies with larger sample size are necessary.
- Subjects
DENTAL extraction; LOCAL anesthesia; MANDIBULAR nerve; LOCAL anesthetics; LIDOCAINE; ROPIVACAINE; POSTOPERATIVE pain prevention; ADRENALINE; COMBINATION drug therapy; COMPARATIVE studies; LONGITUDINAL method; MANDIBLE; RESEARCH methodology; MEDICAL cooperation; NERVE block; POSTOPERATIVE pain; RESEARCH; EVALUATION research; RANDOMIZED controlled trials; TREATMENT effectiveness; BLIND experiment
- Publication
Indian Journal of Dental Research, 2018, Vol 29, Issue 5, p611
- ISSN
0970-9290
- Publication type
Academic Journal
- DOI
10.4103/ijdr.IJDR_150_17