Works matching DE "JANUS kinases"

Results: 1846

Pediatric immune-mediated skin diseases: a review of advancements in biologics and JAK inhibitor treatments.

Published in:

Drugs & Therapy Perspectives, 2025, v. 41, n. 5, p. 192, doi. 10.1007/s40267-025-01160-6

By:

Darchini-Maragheh, Emadodin;
Moussa, Anthony

Publication type:

Article

Janus kinase inhibitors for alopecia areata: a review of clinical data.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1577115

By:

Sun, Yutong;
Li, Qian;
Zhang, Yanli;
Liu, Yaling

Publication type:

Article

Benefits of the Topical JAK Inhibitor Delgocitinib in a Patient With Pediatric Localized Scleroderma.

Published in:

Pediatric Dermatology, 2025, v. 42, n. 3, p. 666, doi. 10.1111/pde.15844

By:

Yamamoto, Mayuko;
Nakajima, Kimiko;
Matsuda, Mayuko;
Takahashi, Aya;
Nakai, Kozo

Publication type:

Article

MPLW515L is a novel somatic activating mutation in myelofibrosis with myeloid metaplasia.

Published in:

2006

By:

Pikman, Yana;
Lee, Benjamin H.;
Mercher, Thomas;
McDowell, Elizabeth;
Ebert, Benjamin L.;
Gozo, Maricel;
Cuker, Adam;
Wernig, Gerlinde;
Moore, Sandra;
Galinsky, Ilene;
DeAngelo, Daniel J.;
Clark, Jennifer J.;
Lee, Stephanie J.;
Golub, Todd R.;
Wadleigh, Martha;
Gilliland, D. Gary;
Levine, Ross L.

Publication type:

journal article

Pharmacological inhibition of the Janus Kinases enhances ASCL1 protein stability and transcriptional activity.

Published in:

Molecular Biology Reports, 2025, v. 52, n. 1, p. 1, doi. 10.1007/s11033-025-10367-9

By:

Hanspal, Maya A.;
Presland, Jeremy;
Shkura, Kirill;
Veiga, Martina Koeva;
Gillotin, Sébastien

Publication type:

Article

Effects of one-year tofacitinib therapy on bone metabolism in rheumatoid arthritis.

Published in:

Osteoporosis International, 2021, v. 32, n. 8, p. 1621, doi. 10.1007/s00198-021-05871-0

By:

Hamar, A.;
Szekanecz, Z.;
Pusztai, A.;
Czókolyová, M.;
Végh, E.;
Pethő, Z.;
Bodnár, N.;
Gulyás, K.;
Horváth, Á.;
Soós, B.;
Bodoki, L.;
Bhattoa, H. P.;
Nagy, G.;
Tajti, G.;
Panyi, G.;
Szekanecz, É.;
Domján, A.;
Hodosi, K.;
Szántó, S.;
Szűcs, G.

Publication type:

Article

Tofacitinib for the treatment of severe rare skin diseases: a narrative review.

Published in:

European Journal of Clinical Pharmacology, 2024, v. 80, n. 4, p. 481, doi. 10.1007/s00228-024-03621-9

By:

Luo, Fenglin;
Zhang, Yuanyuan;
Wang, Ping

Publication type:

Article

JAK inhibitors and risk of major cardiovascular events or venous thromboembolism: a self-controlled case series study.

Published in:

European Journal of Clinical Pharmacology, 2022, v. 78, n. 12, p. 1981, doi. 10.1007/s00228-022-03402-2

By:

Gouverneur, Amandine;
Avouac, Jérôme;
Prati, Clément;
Cracowski, Jean-Luc;
Schaeverbeke, Thierry;
Pariente, Antoine;
Truchetet, Marie-Elise

Publication type:

Article

The safety of systemic Janus kinase inhibitors in atopic dermatitis: a systematic review and network meta-analysis.

Published in:

European Journal of Clinical Pharmacology, 2022, v. 78, n. 12, p. 1923, doi. 10.1007/s00228-022-03400-4

By:

Alves, Carlos;
Penedones, Ana;
Mendes, Diogo;
Batel Marques, Francisco

Publication type:

Article

A drug–drug interaction study to evaluate the impact of peficitinib on OCT1- and MATE1-mediated transport of metformin in healthy volunteers.

Published in:

European Journal of Clinical Pharmacology, 2020, v. 76, n. 8, p. 1135, doi. 10.1007/s00228-020-02876-2

By:

Shibata, Mai;
Toyoshima, Junko;
Kaneko, Yuichiro;
Oda, Kazuo;
Nishimura, Tetsuya

Publication type:

Article

Emerging Treatment Options in Atopic Dermatitis: Systemic Therapies.

Published in:

2018

By:

Nygaard, Uffe;
Vestergaard, Christian;
Deleuran, Mette

Publication type:

journal article

Ruxolitinib use in myelofibrosis patients: the single center experience and the relationship between JAK-2 allele burden and Ruxolitinib response.

Published in:

Pamukkale Medical Journal, 2021, v. 14, n. 2, p. 322, doi. 10.31362/patd.770631

By:

Göçer, Mesut;
Kurtoğlu, Erdal

Publication type:

Article

Xiaoyaosan ameliorates depressive-like behavior and susceptibility to glucose intolerance in rat: involvement of LepR-STAT3/PI3K pathway in hypothalamic arcuate nucleus.

Published in:

BMC Complementary Medicine & Therapies, 2023, v. 23, n. 1, p. 1, doi. 10.1186/s12906-023-03942-9

By:

Qiu, Wenqi;
Wu, Qian;
Zhang, Kaiwen;
Da, Xiaoli;
Tang, Kairui;
Yuan, Naijun;
Deng, Lijuan;
Wu, Mansi;
Zhang, Ying;
Quan, Jiangyan;
Ma, Qingyu;
Li, Xiaojuan;
Chen, Jiaxu

Publication type:

Article

Ayurvedic formulations Guduchi and Madhuyashti triggers JNK signaling mediated immune response and adversely affects Huntington phenotype.

Published in:

BMC Complementary Medicine & Therapies, 2022, v. 22, n. 1, p. 1, doi. 10.1186/s12906-022-03724-9

By:

Singh, Surabhi;
Tapadia, Madhu G.

Publication type:

Article

Naringenin and cryptotanshinone shift the immune response towards Th1 and modulate T regulatory cells via JAK2/STAT3 pathway in breast cancer.

Published in:

BMC Complementary Medicine & Therapies, 2022, v. 22, n. 1, p. 1, doi. 10.1186/s12906-022-03625-x

By:

Noori, Shokoofe;
Nourbakhsh, Mitra;
Imani, Hossein;
Deravi, Niloofar;
Salehi, Niloufar;
Abdolvahabi, Zohreh

Publication type:

Article

Jianpi Qinghua Fomula alleviates insulin resistance via restraining of MAPK pathway to suppress inflammation of the small intestine in DIO mice.

Published in:

BMC Complementary Medicine & Therapies, 2022, v. 22, n. 1, p. 1, doi. 10.1186/s12906-022-03595-0

By:

Liu, Yahua;
Han, Xu;
Cai, Mengjie;
Jin, Shenyi;
Yan, Zihui;
Lu, Hao;
Chen, Qingguang

Publication type:

Article

Chrysoeriol suppresses hyperproliferation of rheumatoid arthritis fibroblast-like synoviocytes and inhibits JAK2/STAT3 signaling.

Published in:

BMC Complementary Medicine & Therapies, 2022, v. 22, n. 1, p. 1, doi. 10.1186/s12906-022-03553-w

By:

Wu, Jia-Ying;
Chen, Ying-Jie;
Fu, Xiu-Qiong;
Li, Jun-Kui;
Chou, Ji-Yao;
Yin, Cheng-Le;
Bai, Jing-Xuan;
Wu, Ying;
Wang, Xiao-Qi;
Li, Amy Sze-man;
Wong, Lut Yi;
Yu, Zhi-Ling

Publication type:

Article

Erosion Regression in Patients with RA After Upadacitinib-A Pilot Study Using High Resolution Peripheral Quantitative Computed Tomography.

Published in:

2024

By:

Cheng, Isaac T;
So, Ho;
Chow, Evelyn H;
Wu, Qihan;
Li, Martin;
Hung, Vivian W;
Qin, Ling;
Wong, Chun Kwok;
Tam, Lai Shan

Publication type:

Abstract

Upadacitinib as Novel Treatment for Rheumatoid Arthritis with T-Cell Granular Lymphocytic Leukemia: A Case Report and Narrative Review.

Published in:

Journal of Clinical Rheumatology & Immunology (JCRI), 2022, v. 22, n. 1, p. 22, doi. 10.1142/S2661341722720026

By:

Young Min Cho;
Anderson, Erik W.;
Guevara, Sara;
Miyara, Santiago J.;
Iqbal, Aqsa;
Aronsohn, Judith;
Molmenti, Ernesto P.;
Mumford, James M.;
Keber, Barbara;
Zonouzi-Zadeh, Farideh;
Yousoun Ha;
Nikolinakos, Petros G.;
Flickinger, Brent

Publication type:

Article

JAK inhibitors dampen activation of interferon-stimulated transcription of ACE2 isoforms in human airway epithelial cells.

Published in:

Communications Biology, 2021, v. 4, n. 1, p. 1, doi. 10.1038/s42003-021-02167-1

By:

Lee, Hye Kyung;
Jung, Olive;
Hennighausen, Lothar

Publication type:

Article

Genetic Association of Juvenile Idiopathic Arthritis With Adult Rheumatic Disease.

Published in:

JAMA Network Open, 2024, v. 7, n. 12, p. e2451341, doi. 10.1001/jamanetworkopen.2024.51341

By:

Fan, Jingxian;
Hao, Jian;
Fu, Yuqiao;
Liu, Xiaoyang;
Qu, Hui-Qi;
Glessner, Joseph T.;
Ji, Dandan;
Liu, Wei;
Zheng, Gang;
Ding, Zhiyong;
Cui, Shuzhong;
Xia, Qianghua;
Hakonarson, Hakon;
Wei, Wei;
Li, Jin

Publication type:

Article

New Studies of Juvenile Idiopathic Arthritis—Complex Genetics of Complex Diseases.

Published in:

2024

By:

Blank, Robert D.

Publication type:

Opinion

Use of Biologic or Targeted Synthetic Disease-Modifying Antirheumatic Drugs and Cancer Risk.

Published in:

JAMA Network Open, 2024, v. 7, n. 11, p. e2446336, doi. 10.1001/jamanetworkopen.2024.46336

By:

Sendaydiego, Xavier;
Gold, Laura S.;
Dubreuil, Maureen;
Andrews, James S.;
Reid, Pankti;
Liew, David F. L.;
Goulabchand, Radjiv;
Singh, Abha Goyal;
Hughes, Grant C.;
Pioro, Mathilde;
Sparks, Jeffrey A.;
Jarvik, Jeffrey G.;
Singh, Siddharth;
Liew, Jean W.;
Singh, Namrata

Publication type:

Article

Cost-Effectiveness of Biosimilars vs Leflunomide in Patients With Rheumatoid Arthritis.

Published in:

JAMA Network Open, 2024, v. 7, n. 6, p. e2418800, doi. 10.1001/jamanetworkopen.2024.18800

By:

Peng, Kuan;
Chan, Shirley C. W.;
Wang, Yang;
Cheng, Franco W. T.;
Yeung, Winnie W. Y.;
Jiao, Yuanshi;
Chan, Esther W. Y.;
Wong, Ian C. K.;
Lau, Chak-Sing;
Li, Xue

Publication type:

Article

Sarilumab reduces disease activity in rheumatoid arthritis patients with inadequate response to janus kinase inhibitors or tocilizumab in regular care in Germany.

Published in:

Rheumatology Advances in Practice, 2022, v. 6, n. 1, p. 1, doi. 10.1093/rap/rkac002

By:

Tony, Hans-Peter;
Feist, Eugen;
Aries, Peer Malte;
Zinke, Silke;
Krüger, Klaus;
Ahlers, Jonas;
Albrecht, Inka;
Barrionuevo, Christian;
Kalus, Stefanie;
Burkhardt, Harald

Publication type:

Article

Inequality of access to advanced therapies for patients with inflammatory arthritis: a postcode lottery?

Published in:

Rheumatology Advances in Practice, 2021, v. 5, n. 3, p. 1, doi. 10.1093/rap/rkab081

By:

Kaul, Arvind;
Mistry, Jatin;
Iagnocco, Annamaria;
Baraliakos, Xenofon;
Bosworth, Ailsa;
McNicol, Iain

Publication type:

Article

Refractory Takayasu arteritis responding to the oral Janus kinase inhibitor, tofacitinib.

Published in:

Rheumatology Advances in Practice, 2020, v. 4, n. 1, p. 1, doi. 10.1093/rap/rkz050

By:

Yamamura, Yuriko;
Matsumoto, Yoshinori;
Asano, Yosuke;
Katayama, Yu;
Hayashi, Keigo;
Ohashi, Keiji;
Morishita, Michiko;
Watanabe, Haruki;
Takano-Narazaki, Mariko;
Sada, Ken-Ei;
Wada, Jun

Publication type:

Article

Current and Emerging Targeted Therapies for Ulcerative Colitis.

Published in:

Visceral Medicine, 2023, v. 39, n. 2, p. 46, doi. 10.1159/000530983

By:

Pietschner, Robert;
Rath, Timo;
Neurath, Markus F.;
Atreya, Raja

Publication type:

Article

异硫氰酸异丁酯抑制肝癌细胞 HepG2 生长的效应与机理.

Published in:

Journal of Central China Normal University, 2022, v. 56, n. 5, p. 834, doi. 10.19603/j.cnki.1000-1190.2022.05.013

By:

周巧巧;
匡政坤;
张洪权;
熊丽;
周诗毅

Publication type:

Article

Analysis of Adverse Events With Janus Kinase Inhibitors Reported to Spontaneous Reporting System.

Published in:

Pharmaceutical & Biomedical Research, 2024, v. 10, n. 3, p. 203, doi. 10.32598/PBR.10.3.1207.3

By:

Tanaka, Hideyuki;
Maezawa, Mika;
Nakao, Natoshi;
Miyasaka, Koumi;
Hirofuji, Sakiko;
Yamashita, Moe;
Matsui, Kensuke;
Ichihara, Nanaka;
Nokura, Yuka;
Iwata, Mari;
Kitamura, Mayumi;
Horibe, Megumi;
Tamaki, Hirofumi;
Iguchi, Kazuhiro;
Nakamura, Mitsuhiro

Publication type:

Article

Filgotinib Improves Experimental Pulmonary Fibrosis by Modulating JAK1/STAT3/SOCS3/IL‐17A Signalling.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2025, v. 136, n. 4, p. 1, doi. 10.1111/bcpt.70012

By:

Lv, Yunying;
Zhang, Guanghua;
Kong, Dexin;
Jiang, Wanglin

Publication type:

Article

Janus kinase 2 V617F mutation and thrombotic events in Behcet's disease: The Alexandria experience.

Published in:

2016

By:

Adeeb, Fahd;
Tayel, Manal;
El Kaffash, Dalal M.;
Idris, Khairunnisa Mohd;
Abu Hassan, Muhammad Fikri;
Fraser, Alexander Duncan

Publication type:

Abstract

A JAK of all trades: how global phosphoproteomics reveal the Achilles heel of MPNs.

Published in:

Molecular & Cellular Oncology, 2021, v. 8, n. 2, p. 1, doi. 10.1080/23723556.2020.1871172

By:

Schnoeder, Tina M.;
Perner, Florian;
Heidel, Florian H.

Publication type:

Article

JAK3 mutations and HOXA9 expression are important cooperating events in T-cell acute lymphoblastic leukemia.

Published in:

Molecular & Cellular Oncology, 2018, v. 5, n. 3, p. 1, doi. 10.1080/23723556.2018.1458014

By:

de Bock, Charles E.;
Cools, Jan

Publication type:

Article

Tumor growth inhibition and tumor specific immunity enhancement in endometrial carcinoma by high intensity focused ultrasound.

Published in:

European Journal of Gynaecological Oncology, 2023, v. 44, n. 5, p. 110, doi. 10.22514/ejgo.2023.085

By:

Shaohua Yuan;
Peng Gu;
Wukui Huang;
Fen Li;
Xiwen Fan

Publication type:

Article

The downregulation of microRNA-375 in human cervical squamous cell carcinoma promotes invasion and migration by targeting JAK2.

Published in:

European Journal of Gynaecological Oncology, 2020, v. 41, n. 6, p. 982, doi. 10.31083/j.ejgo.2020.06.5209

By:

Huichao Xiao;
Lei Zheng

Publication type:

Article

Association Between Janus Kinase Inhibitors Therapy and Mental Health Outcome in Rheumatoid Arthritis: A Systematic Review and Meta-analysis.

Published in:

Rheumatology & Therapy, 2022, v. 9, n. 2, p. 313, doi. 10.1007/s40744-021-00409-6

By:

Shamail, Ghazala M. H.;
Haridoss, Madhumitha;
Natarajan, Meenakumari;
Joshua, Vasna;
Bagepally, Bhavani Shankara

Publication type:

Article

Psoriatic Arthritis: The Influence of Co-morbidities on Drug Choice.

Published in:

Rheumatology & Therapy, 2022, v. 9, n. 1, p. 49, doi. 10.1007/s40744-021-00397-7

By:

Patel, Sneha;
Kumthekar, Anand

Publication type:

Article

Efficacy of Tofacitinib for the Treatment of Psoriatic Arthritis: Pooled Analysis of Two Phase 3 Studies.

Published in:

Rheumatology & Therapy, 2018, v. 5, n. 2, p. 567, doi. 10.1007/s40744-018-0131-5

By:

Nash, Peter;
Coates, Laura C.;
Fleischmann, Roy;
Papp, Kim A.;
Gomez-Reino, Juan Jesus;
Kanik, Keith S.;
Wang, Cunshan;
Wu, Joseph;
Menon, Sujatha;
Hendrikx, Thijs;
Ports, William C.

Publication type:

Article

Treatment Patterns of Newly Diagnosed Rheumatoid Arthritis Patients from a Commercially Insured Population.

Published in:

Rheumatology & Therapy, 2018, v. 5, n. 2, p. 355, doi. 10.1007/s40744-018-0114-6

By:

Kern, David M.;
Chang, Lawrence;
Sonawane, Kalyani;
Larmore, Cynthia J.;
Boytsov, Natalie N.;
Quimbo, Ralph A.;
Singer, Joseph;
Hinton, John T.;
Wu, Sze-jung;
Araujo, Andre B.

Publication type:

Article

Tofacitinib, an Oral Janus Kinase Inhibitor: Pooled Efficacy and Safety Analyses in an Australian Rheumatoid Arthritis Population.

Published in:

Rheumatology & Therapy, 2018, v. 5, n. 2, p. 383, doi. 10.1007/s40744-018-0118-2

By:

Hall, Stephen;
Nash, Peter;
Rischmueller, Maureen;
Bossingham, David;
Bird, Paul;
Cook, Nicola;
Witcombe, David;
Soma, Koshika;
Kwok, Kenneth;
Thirunavukkarasu, Krishan

Publication type:

Article

Long-Term Radiographic and Patient-Reported Outcomes in Patients with Rheumatoid Arthritis Treated with Tofacitinib: ORAL Start and ORAL Scan Post-hoc Analyses.

Published in:

Rheumatology & Therapy, 2018, v. 5, n. 2, p. 341, doi. 10.1007/s40744-018-0113-7

By:

Strand, Vibeke;
Kavanaugh, Arthur;
Kivitz, Alan J.;
van der Heijde, Désirée;
Kwok, Kenneth;
Akylbekova, Ermeg;
Soonasra, Arif;
Snyder, Mark;
Connell, Carol;
Bananis, Eustratios;
Smolen, Josef S.

Publication type:

Article

Effect of Discontinuation or Initiation of Methotrexate or Glucocorticoids on Tofacitinib Efficacy in Patients with Rheumatoid Arthritis: A Post Hoc Analysis.

Published in:

Rheumatology & Therapy, 2018, v. 5, n. 1, p. 203, doi. 10.1007/s40744-018-0093-7

By:

Fleischmann, Roy;
Wollenhaupt, Jürgen;
Cohen, Stanley;
Wang, Lisy;
Fan, Haiyun;
Bandi, Vara;
Andrews, John;
Takiya, Liza;
Bananis, Eustratios;
Weinblatt, Michael E.

Publication type:

Article

Worldwide, 3-Year, Post-Marketing Surveillance Experience with Tofacitinib in Rheumatoid Arthritis.

Published in:

Rheumatology & Therapy, 2018, v. 5, n. 1, p. 283, doi. 10.1007/s40744-018-0097-3

By:

Cohen, Stanley;
Curtis, Jeffrey R.;
DeMasi, Ryan;
Chen, Yan;
Fan, Haiyun;
Soonasra, Arif;
Fleischmann, Roy

Publication type:

Article

Atopic dermatitis: new insights into a common condition.

Published in:

British Journal of Community Nursing, 2024, v. 29, n. 10, p. 490, doi. 10.12968/bjcn.2024.0113

By:

Greener, Mark

Publication type:

Article

Efficacy of baricitinib in severe coronavirus disease 2019.

Published in:

Egyptian Journal of Chest Diseases & Tuberculosis, 2023, v. 72, n. 3, p. 355, doi. 10.4103/ecdt.ecdt_83_22

By:

Amer, Ahmed M. A. E. F.;
Mousa, Doaa B.;
Ahmed, Azza A.

Publication type:

Article

Inhibition of tumor growth and angiogenesis of tamoxifen-resistant breast cancer cells by ruxolitinib, a selective JAK2 inhibitor.

Published in:

Oncology Letters, 2019, v. 17, n. 4, p. 3981

By:

Kim, Ji Won;
Gautam, Jaya;
Kim, Ji Eun;
Kim, Jung-Ae;
Kang, Keon Wook

Publication type:

Article

Ganoderic acid A exerts antitumor activity against MDA-MB-231 human breast cancer cells by inhibiting the Janus kinase 2/signal transducer and activator of transcription 3 signaling pathway.

Published in:

Oncology Letters, 2018, v. 16, n. 5, p. 6515, doi. 10.3892/ol.2018.9475

By:

Yang, Yuguang;
Zhou, Hongfeng;
Liu, Wenming;
Wu, Jin;
Yue, Xiaolong;
Wang, Jincai;
Quan, Lina;
Liu, Hang;
Guo, Li;
Wang, Zhipeng;
Lian, Xin;
Zhang, Qingyuan

Publication type:

Article

AG490 reverses phenotypic alteration of dendritic cells by bladder cancer cells.

Published in:

Oncology Letters, 2018, v. 16, n. 3, p. 2851, doi. 10.3892/ol.2018.9028

By:

Xiu, Weigang;
Ma, Juan;
Lei, Ting;
Zhang, Man

Publication type:

Article

An indel polymorphism in the 3' untranslated region of JAK1 confers risk for hepatocellular carcinoma possibly by regulating JAK1 transcriptional activity in a Chinese population.

Published in:

Oncology Letters, 2018, v. 15, n. 5, p. 8088, doi. 10.3892/ol.2018.8347

By:

Yu, Qiang;
Qian, Weifeng;
Wang, Jian;
Wu, Yejiao;
Zhang, Jinkun;
Chen, Weichang

Publication type:

Article