Clinical evaluation of the efficacy of bioactive glass and strontium chloride for treatment of dentinal hypersensitivity.

Ananthakrishna, Suryaprakash; Raghu, Tumkur Naryanappa; Koshy, Sunil; Kumar, Naveen

Objective: Bioactive glass is a calcium sodium phosphosilicate material (24.5% CaO, 24.5% Na2O, 6.0% P2O5, and 45% SiO2) that was originally developed as an implant material to regenerate bone and recently adapted for use in oral care products (NovaMin®, NovaMin Technology Inc.). NovaMin reacts rapidly with saliva to release sodium, which increases the salivary pH, as well as calcium and phosphate, creating the ideal conditions for tooth remineralization. NovaMin has been shown to occlude dentinal tubules and remineralize dentin; therefore, it could be used in the treatment of dentinal hypersensitivity. Thus, the aim of this study was to compare in vivo the effect of NovaMin and 10% strontium chloride containing dentifrices on dentinal hypersensitivity in a 6-week clinical study. Materials and Methods: Forty subjects were evaluated clinically for dentinal hypersensitivity using air blast method (dental air syringe) and cold water method, along with subjective perception of pain (0-10 scale) at baseline and at 2, 4, and 6 weeks. The subjects were then randomly divided into two groups and each group was treated with one of the two test dentifrices. Results: There was a general decrease in dentinal hypersensitivity levels in both the groups over 6 weeks, but there was a statistically greater difference in hypersensitivity at 2, 4, and 6 weeks in the group treated with DenShield™ (NovaMin containing dentifrice) when compared with the Senolin® (strontium chloride containing dentifrice) group.

STRONTIUM chloride; TOOTH sensitivity; NOVAMIN Technology Inc.; REMINERALIZATION (Teeth); TOOTH abrasion; THERAPEUTICS

Journal of Interdisciplinary Dentistry, 2012, Vol 2, Issue 2, p92

2229-5194

Academic Journal

10.4103/2229-5194.100600