Retinal Vessel Caliber, Choroidal Thickness and Ocular Pulse Amplitude Measurements in Essential Thrombocythemia.

Pekel, Gökhan; Doğu, Mehmet Hilmi; Sarı, Hakan Ismail; Acer, Semra; Kasikci, Alper; Yagci, Ramazan; Çetin, Ebru Nevin

Purpose: The choroid and retina receive most of the blood that enter to the eye, and this uptake may be affected by essential thrombocythemia (ET) in which thrombosis and hemorrhage is common. This study compares choroidal thickness, retinal vascular caliber, and ocular pulse amplitude (OPA) measurements between patients with ET and healthy adults. Materials and Methods: Thirty‑seven patients with ET and 37 age‑sex‑matched healthy adults were recruited in this cross‑sectional and comparative study. Spectral‑domain optical coherence tomography was used to measure the subfoveal choroidal thickness (SFCT) and retinal vascular caliber measurements. The Pascal dynamic contour tonometer was used for OPA and intraocular pressure (IOP) measurements. The independent samples t‑test was used for comparison of measurements between the groups. Pearson’s correlation coefficient analysis was used to detect correlations between the variables. A P 0.05, all comparisons). Blood platelet counts were not associated with choroidal thickness, OPA, and IOP (P > 0.05). Retinal arteriolar and venular calibers were statistically, significantly thicker in healthy controls when compared to the study group (P < 0.05). Conclusions: Our results indicate that choroidal thickness and pulsatile blood flow are not significantly affected in ET and under high blood platelet counts. Retinal arteriolar and venular calibers are thinner in ET when compared to age‑sex matched healthy controls.

THROMBOCYTOPENIA treatment; RETINAL blood vessels; PULSE amplitude modulation; BLOOD platelets; STATISTICAL significance

Middle East African Journal of Ophthalmology, 2016, Vol 23, Issue 1, p84

0974-9233

Academic Journal

10.4103/0974-9233.171827