Results
Title

Neopterin and mini-mental state examination scores, two independent risk factors for postoperative delirium in elderly patients with open abdominal surgery.

Authors

Suqin Miao; Peipei Shen; Qiong Zhang; Huijuan Wang; Jinchun Shen; Gang Wang; Dezhen Lv; Miao, Suqin; Shen, Peipei; Zhang, Qiong; Wang, Huijuan; Shen, Jinchun; Wang, Gang; Lv, Dezhen

Abstract

Background: Postoperative delirium is described as one of the most common complications for elderly patients with unknown pathophysiological pathways. In this present study, we analyzed the clinical and biochemical parameters in elderly patients with or without a delirium after open abdominal surgery to investigate the possible predicative factors for a delirium.Materials and Methods: Patients aged ≥60 years scheduled to undergo elective gastrointestinal tumor resection via laparotomy from July 2012 to June 2015 were enrolled in this study. Demographic and clinical data, characteristics of the surgical and anesthetic procedure, biochemical parameters were compared between patients with or without a delirium. Multivariate logistic regression testing was used for the evaluation of independent risk factors for postoperative delirium.Results: Overall, 112 participants were enrolled in this study, 49 of which were diagnosed with postoperative delirium. Patients with a delirium had an older age (P = 0.013) and a lower Mini-Mental State Examination (MMSE) score (P Conclusions: Our present study suggested the potential roles of neopterin and MMSE scores in the pathophysiology and prediction of delirium in elderly patients after open abdominal surgery.

Subjects

DELIRIUM; DISEASE complications; PATHOLOGICAL physiology; LOGISTIC regression analysis; POSTOPERATIVE care; DIAGNOSIS of delirium; C-reactive protein; COENZYMES; DIGESTIVE organ surgery; INTERLEUKINS; LONGITUDINAL method; PROGNOSIS; PSYCHOLOGICAL tests; SOMATOMEDIN; SURGICAL complications; GASTROINTESTINAL tumors; CASE-control method

Publication

Journal of Cancer Research & Therapeutics, 2018, Vol 14, Issue 6, p1234

ISSN

0973-1482

Publication type

Academic Journal

DOI

10.4103/0973-1482.192764