Title: Eflornithine.
Authors: Jobanputra, Kruti S.; Rajpal, Aruna V.; Nagpur, N. G.
Abstract: The article describes eflornithine as a drug for the reduction of hirsutism in women. It is stated that eflornithine was synthesized as anti-cancer agent in 1970 and is later indicated for the reduction of facial hair growth in women irrespective of the cause of hair growth. Eflornithine irreversibly inhibits the enzyme ornithine decarboxylase which is responsible for hair growth.
Subjects: ENZYME inhibitors; ANTINEOPLASTIC agents; ORNITHINE decarboxylase; HYPERTRICHOSIS; FACIAL abnormalities; WOMEN; HAIR removal; HAIR follicles; CUTANEOUS therapeutics; EFLORNITHINE; PHARMACODYNAMICS
Publication: Indian Journal of Dermatology, Venereology & Leprology, 2007, Vol 73, Issue 5, p365
ISSN: 0378-6323
Publication type: Academic Journal
DOI: 10.4103/0378-6323.35752

Eflornithine.

Jobanputra, Kruti S.; Rajpal, Aruna V.; Nagpur, N. G.