Inhaled nitric oxide for the brain dead donor with neurogenic pulmonary edema during anesthesia for organ donation.

Eun Sun Park; Hee Won Son; A-Ran Lee; Sang Hyun Lee; An Suk Kim; Soon Eun Park; Young Woo Cho

Neurogenic pulmonary edema (NPE) in brain dead organ donors occurring after an acute central nervous system insult threatens organ preservation of potential organ donors and the outcome of organ donation. Hence the active and immediate management of NPE is critical. In this case, a 50-year-old male was admitted to the intensive care unit (ICU) for organ donation. He was hypoxic due to NPE induced by spontaneous intracerebral hemorrhage and intraventricular hemorrhage. Protective ventilatory management, intermittent recruitment maneuvers, and supportive treatment were maintained in the ICU and the operating room (OR). Despite this management, the hypoxemia worsened after the OR admission. So inhaled nitric oxide (NO) therapy was performed during the operation, and the hypoxic phenomena showed remarkable improvement. The organ retrieval was successfully completed. Therefore, NO inhalation can be help-ful in the improvement of hypoxemia caused by NPE in brain dead organ donors during anesthesia for the organ donation.

ORGAN donation; THERAPEUTIC use of nitric oxide; INTENSIVE care units; HYPOXEMIA; ORGAN donors; BRAIN death; ANESTHESIA; PATIENTS

Korean Journal of Anesthesiology, 2014, Vol 67, Issue 2, p133

2005-6419

Academic Journal

10.4097/kjae.2014.67.2.133