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Title

Identification and Validation of Symptom Clusters in Patients with Hepatocellular Carcinoma.

Authors

Myung Sook Cho; In Gak Kwon; Hee Sun Kim; Kyunghee Kim; Eunjung Ryu

Abstract

Purpose: The purpose of this study was to identify cancer-related symptom clusters and to validate the conceptual meanings of the revealed symptom clusters in patients with hepatocellular carcinoma. Methods: This study was a cross-sectional survey and methodological study. Patients with hepatocellular carcinoma (N=194) were recruited from a medical center in Seoul. The 20-item Symptom Checklist was used to assess patients' symptom severity. Selected symptoms were factored using principal-axis factoring with varimax rotation. To validate the revealed symptom clusters, the statistical differences were analyzed by status of patients' performance status, Child-Pugh classification, and mood state among symptom clusters. Results: Fatigue was the most prevalent symptom (97.4%), followed by lack of energy and stomach discomfort. Patients' symptom severity ratings fit a four-factor solution that explained 61.04% of the variance. These four factors were named pain-appetite cluster, fatigue cluster, itching-constipation cluster, and gastrointestinal cluster. The revealed symptom clusters were significantly different for patient performance status (ECOG-PSR), Child-Pugh class, anxiety, and depression. Conclusion: Knowing these symptom clusters may help nurses to understand reasonable mechanisms for the aggregation of symptoms. Efficient symptom management of disease-related and treatment-related symptoms is critical in promoting physical and emotional status in patients with hepatocellular carcinoma.

Subjects

SEOUL (Korea); KOREA; LIVER cancer; SYMPTOMS; PSYCHOLOGICAL stress; MEDICAL centers; ITCHING; CONSTIPATION; GASTROINTESTINAL diseases

Publication

Journal of Korean Academy of Nursing, 2009, Vol 39, Issue 5, p683

ISSN

2005-3673

Publication type

Academic Journal

DOI

10.4040/jkan.2009.39.5.683

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