Title: The cumulative analgesic effect of repeated electroacupuncture involves synaptic remodeling in the hippocampal CA3 region.
Authors: Qiuling Xu; Tao Liu; Shuping Chen; Yonghui Gao; Junying Wang; Lina Qiao; Junling Liu
Abstract: The article discusses a study which found that the cumulative analgesic effect of repeated electroacupuncture involves synaptic remodeling in the hippocampal CA3 region in ovariectomized rats with chronic constriction injury (CCI)-induced neuropathic pain on the sciatic nerve. Analysis revealed that electroacupuncture decreases pain reaction after CCI and reduces synaptic cleft width between hippocampal neurons. It increased post-synaptic density and active zone length in hippocampal neurons.
Subjects: ANALGESICS; ELECTROACUPUNCTURE; HIPPOCAMPUS (Brain); SCIATIC nerve; PAIN
Publication: Neural Regeneration Research, 2012, Vol 7, Issue 18, p1378
ISSN: 1673-5374
Publication type: Academic Journal
DOI: 10.3969/j.issn.1673-5374.2012.18.003

The cumulative analgesic effect of repeated electroacupuncture involves synaptic remodeling in the hippocampal CA3 region.

Qiuling Xu; Tao Liu; Shuping Chen; Yonghui Gao; Junying Wang; Lina Qiao; Junling Liu