Works matching AU Nagai, Noriaki

Results: 103

Dermal formulation based on carbopol and Gum Arabic improves skin retention of indomethacin.

Published in:

PLoS ONE, 2025, v. 20, n. 6, p. 1, doi. 10.1371/journal.pone.0326051

By:

Otake, Hiroko;
Fumihiko, Ogata;
Nakazawa, Yosuke;
Misra, Manju;
Tsubaki, Masanobu;
Kawasaki, Naohito;
Nagai, Noriaki

Publication type:

Article

Evaluation of starch granules based on hydroxypropylcellulose as a substitute for excipient lactose.

Published in:

Journal of Pharmaceutical Health Care & Sciences, 2024, v. 10, n. 1, p. 1, doi. 10.1186/s40780-024-00354-w

By:

Yoshikawa, Tomohiro;
Okamoto, Hiroyo;
Takeuchi, Kenta;
Hirata, Atsushi;
Otake, Hiroko;
Nagai, Noriaki

Publication type:

Article

Recovery from indomethacin-induced gastrointestinal bleeding by treatment with teprenone.

Published in:

Journal of Pharmaceutical Health Care & Sciences, 2023, v. 9, n. 1, p. 1, doi. 10.1186/s40780-023-00312-y

By:

Deguchi, Saori;
Iwakami, Ayusa;
Tujigiwa, Mizuki;
Otake, Hiroko;
Mano, Yu;
Yamamoto, Naoki;
Nakazawa, Yosuke;
Misra, Manju;
Nagai, Noriaki

Publication type:

Article

Recovery from indomethacin-induced gastrointestinal bleeding by treatment with teprenone.

Published in:

Journal of Pharmaceutical Health Care & Sciences, 2023, v. 9, n. 1, p. 1, doi. 10.1186/s40780-023-00312-y

By:

Deguchi, Saori;
Iwakami, Ayusa;
Tujigiwa, Mizuki;
Otake, Hiroko;
Mano, Yu;
Yamamoto, Naoki;
Nakazawa, Yosuke;
Misra, Manju;
Nagai, Noriaki

Publication type:

Article

Skin absorption of felbinac solid nanoparticles in gel formulation containing l-menthol and carboxypolymethylene.

Published in:

Journal of Pharmaceutical Health Care & Sciences, 2023, v. 9, n. 1, p. 1, doi. 10.1186/s40780-023-00290-1

By:

Kadowaki, Reita;
Ogata, Fumihiko;
Fushiki, Aoi;
Daimyo, Saki;
Deguchi, Saori;
Otake, Hiroko;
Nagata, Mayumi;
Sasaki, Hiroshi;
Kawasaki, Naohito;
Nagai, Noriaki

Publication type:

Article

Comparison of early posttreatment effects of two steroidal anti‐inflammatory ophthalmic drugs on the ocular inflammatory response induced by paracentesis in healthy canine eyes.

Published in:

Veterinary Ophthalmology, 2019, v. 22, n. 5, p. 607, doi. 10.1111/vop.12629

By:

Sato, Kazuaki;
Iwasaki, Kiwako;
Nagai, Noriaki;
Yamashita, Yohei;
Chikazawa, Seishiro;
Hoshi, Fumio;
Kanai, Kazutaka

Publication type:

Article

Nasal Absorption Enhancement of Mometasone Furoate Nanocrystal Dispersions.

Published in:

International Journal of Nanomedicine, 2023, v. 18, p. 5685, doi. 10.2147/IJN.S430952

By:

Masuda, Shuya;
Deguchi, Saori;
Ogata, Fumihiko;
Yoshitomi, Joji;
Otake, Hiroko;
Kanai, Kazutaka;
Kawasaki, Naohito;
Nagai, Noriaki

Publication type:

Article

Fixed-Combination Eye Drops Based on Fluorometholone Nanoparticles and Bromfenac/Levofloxacin Solution Improve Drug Corneal Penetration.

Published in:

International Journal of Nanomedicine, 2021, v. 16, p. 5343, doi. 10.2147/IJN.S317046

By:

Otake, Hiroko;
Goto, Ryoka;
Ogata, Fumihiko;
Isaka, Takumi;
Kawasaki, Naohito;
Kobayakawa, Shinichiro;
Matsunaga, Toru;
Nagai, Noriaki

Publication type:

Article

Drug Delivery System Based On Minoxidil Nanoparticles Promotes Hair Growth In C57BL/6 Mice.

Published in:

International Journal of Nanomedicine, 2019, v. 14, p. 7921, doi. 10.2147/IJN.S225496

By:

Nagai, Noriaki;
Iwai, Yoshie;
Sakamoto, Akane;
Otake, Hiroko;
Oaku, Yoshihiro;
Abe, Akinari;
Nagahama, Tohru

Publication type:

Article

Energy-dependent endocytosis is responsible for drug transcorneal penetration following the instillation of ophthalmic formulations containing indomethacin nanoparticles.

Published in:

International Journal of Nanomedicine, 2019, v. 14, p. 1213, doi. 10.2147/IJN.S196681

By:

Nagai, Noriaki;
Ogata, Fumihiko;
Otake, Hiroko;
Nakazawa, Yosuke;
Kawasaki, Naohito

Publication type:

Article

Design of a transdermal formulation containing raloxifene nanoparticles for osteoporosis treatment.

Published in:

International Journal of Nanomedicine, 2018, v. 13, p. 5215, doi. 10.2147/IJN.S173216

By:

Nagai, Noriaki;
Ogata, Fumihiko;
Otake, Hiroko;
Nakazawa, Yosuke;
Kawasaki, Naohito

Publication type:

Article

High ambient temperature may induce presbyopia via TRPV1 activation.

Published in:

Medical Molecular Morphology, 2024, v. 57, n. 4, p. 268, doi. 10.1007/s00795-024-00391-2

By:

Nakazawa, Yosuke;
Kuno, Yumika;
Shimada, Hibiki;
Nagai, Noriaki;
Hiramatsu, Noriko;
Takeda, Shun;
Yamamoto, Naoki;
Funakoshi-Tago, Megumi;
Sasaki, Hiroshi

Publication type:

Article

Aquaporins contribute to vacuoles formation in Nile grass type II diabetic rats.

Published in:

Medical Molecular Morphology, 2023, v. 56, n. 4, p. 274, doi. 10.1007/s00795-023-00365-w

By:

Aihara, Kana;
Nakazawa, Yosuke;
Takeda, Shun;
Hatsusaka, Natsuko;
Onouchi, Takanori;
Hiramatsu, Noriko;
Nagata, Mayumi;
Nagai, Noriaki;
Funakoshi-Tago, Megumi;
Yamamoto, Naoki;
Sasaki, Hiroshi

Publication type:

Article

Iris-derived induced pluripotent stem cells that express GFP in all somatic cells of mice and differentiate into functional retinal neurons.

Published in:

Medical Molecular Morphology, 2022, v. 55, n. 4, p. 292, doi. 10.1007/s00795-022-00330-z

By:

Hiramatsu, Noriko;
Yamamoto, Naoki;
Ohkuma, Mahito;
Nagai, Noriaki;
Miyachi, Ei-ichi;
Yamatsuta, Kumiko;
Imaizumi, Kazuyoshi

Publication type:

Article

Morphological comparison between three-dimensional structure of immortalized human lens epithelial cells and Soemmering's ring.

Published in:

Medical Molecular Morphology, 2021, v. 54, n. 3, p. 216, doi. 10.1007/s00795-021-00280-y

By:

Hiramatsu, Noriko;
Nagai, Noriaki;
Kondo, Masashi;
Imaizumi, Kazuyoshi;
Sasaki, Hiroshi;
Yamamoto, Naoki

Publication type:

Article

Changes in Protein Expression in Warmed Human Lens Epithelium Cells Using Shotgun Proteomics.

Published in:

Medicina (1010660X), 2025, v. 61, n. 2, p. 286, doi. 10.3390/medicina61020286

By:

Otake, Hiroko;
Yamamoto, Tetsushi;
Yamamoto, Naoki;
Nakazawa, Yosuke;
Miyata, Yoshiki;
Taga, Atsushi;
Sasaki, Hiroshi;
Nagai, Noriaki

Publication type:

Article

Oxaliplatin and 5-fluorouracil promote epithelial-mesenchymal transition via activation of KRAS/ERK/NF-κB pathway in KRAS-mutated colon cancer cells.

Published in:

Molecular & Cellular Biochemistry, 2025, v. 480, n. 5, p. 2985, doi. 10.1007/s11010-024-05157-z

By:

Hoshida, Tadafumi;
Tsubaki, Masanobu;
Takeda, Tomoya;
Asano, Ryota;
Choi, Ik-hyun;
Takimoto, Koudai;
Inukai, Ayano;
Imano, Motohiro;
Tanabe, Kazufumi;
Nagai, Noriaki;
Nishida, Shozo

Publication type:

Article

Development of diabetes mellitus following hormone therapy in prostate cancer patients is associated with early progression to castration resistance.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-96584-1

By:

Hayashi, Tomonori;
Miyamoto, Tomoyoshi;
Nagai, Noriaki;
Kawabata, Atsufumi

Publication type:

Article

Evaluation of Adsorption Mechanism of Chromium(VI) Ion Using Ni-Al Type and Ni-Al-Zr Type Hydroxides.

Published in:

Water (20734441), 2021, v. 13, n. 4, p. 551, doi. 10.3390/w13040551

By:

Ogata, Fumihiko;
Nagai, Noriaki;
Tabuchi, Ayako;
Toda, Megumu;
Otani, Masashi;
Saenjum, Chalermpong;
Nakamura, Takehiro;
Kawasaki, Naohito;
Palet, Cristina;
Bastos-Arrieta, Julio

Publication type:

Article

Removal of Arsenic(III) Ion from Aqueous Media Using Complex Nickel-Aluminum and Nickel-Aluminum-Zirconium Hydroxides.

Published in:

Water (20734441), 2020, v. 12, n. 6, p. 1697, doi. 10.3390/w12061697

By:

Ogata, Fumihiko;
Nagai, Noriaki;
Toda, Megumu;
Otani, Masashi;
Saenjum, Chalermpong;
Nakamura, Takehiro;
Kawasaki, Naohito

Publication type:

Article

The role of preoperative gadolinium enhanced magnetic resonance imaging (MRI) in anticipating postoperative middle ear aeration after canal wall up tympanoplasty for cholesteatoma.

Published in:

2016

By:

Nagai, Noriaki;
Tono, Tetsuya;
Mtsuda, Keiji;
Hirahara, Shinya

Publication type:

Abstract

Formation of three-dimensional cell aggregates expressing lens-specific proteins in various cultures of human iris-derived tissue cells and iPS cells.

Published in:

Experimental & Therapeutic Medicine, 2022, v. 24, n. 2, p. N.PAG, doi. 10.3892/etm.2022.11476

By:

Hiramatsu, Noriko;
Yamamoto, Naoki;
Kato, Yu;
Nagai, Noriaki;
Isogai, Sumito;
Imaizumi, Kazuyoshi

Publication type:

Article

Effect of inner physical properties on powder adhesion in inhalation capsules in case of a high resistance device.

Published in:

Experimental & Therapeutic Medicine, 2021, v. 22, n. 6, p. N.PAG, doi. 10.3892/etm.2021.10788

By:

Otake, Hiroko;
Minami, Misa;
Yamaguchi, Mizuki;
Akiyama, Sawako;
Inaba, Kazunori;
Nagai, Noriaki

Publication type:

Article

Coffee brew intake can prevent the reduction of lens glutathione and ascorbic acid levels in HFD-fed animals.

Published in:

Experimental & Therapeutic Medicine, 2019, v. 17, n. 2, p. 1420

By:

Nakazawa, Yosuke;
Ishimori, Nana;
Oguchi, Jun;
Nagai, Noriaki;
Kimura, Masaki;
Funakoshi-Tago, Megumi;
Tamura, Hiroomi

Publication type:

Article

Enhanced percutaneous absorption of cilostazol nanocrystals using aqueous gel patch systems and clarification of the absorption mechanism.

Published in:

Experimental & Therapeutic Medicine, 2018, v. 15, n. 4, p. 3501, doi. 10.3892/etm.2018.5820

By:

Yoshioka, Chiaki;
Ito, Yoshimasa;
Nagai, Noriaki

Publication type:

Article

An oral formulation of cilostazol nanoparticles enhances intestinal drug absorption in rats.

Published in:

Experimental & Therapeutic Medicine, 2018, v. 15, n. 1, p. 454, doi. 10.3892/etm.2017.5373

By:

Yoshioka, Chiaki;
Ito, Yoshimasa;
Nagai, Noriaki

Publication type:

Article

MDM2 inhibitors induce apoptosis by suppressing MDM2 and enhancing p53, Bax, Puma and Noxa expression levels in imatinib‑resistant chronic myeloid leukemia cells.

Published in:

Biomedical Reports, 2025, v. 22, n. 4, p. N.PAG, doi. 10.3892/br.2025.1943

By:

Kimura, Akihiro;
Tsubaki, Masanobu;
Obana, Teruki;
Matsuo, Taira;
Komori, Rie;
Nagai, Noriaki;
Yamamoto, Tetsushi;
Nishida, Shozo

Publication type:

Article

Proteomic profile of the lens in a streptozotocin-induced diabetic rat model using shotgun proteomics.

Published in:

Biomedical Reports, 2017, v. 7, n. 5, p. 445, doi. 10.3892/br.2017.988

By:

NORIAKI NAGAI;
TETSUSHI YAMAMOTO;
KUNIKO MITAMURA;
ATSUSHI TAGA

Publication type:

Article

Copolymerized Polymers Based on Cyclodextrins and Cationic Groups Enhance Therapeutic Effect of Rebamipide in the N-Acetylcysteine-Treated Dry Eye Model.

Published in:

Drug Design, Development & Therapy, 2024, v. 18, p. 4345, doi. 10.2147/DDDT.S469445

By:

Otake, Hiroko;
Kobayashi, Ko;
Kadowaki, Reita;
Kosaka, Taiyo;
Itahashi, Mizuki;
Tsubaki, Masanobu;
Matsuda, Masaru;
Iwakiri, Norio;
Harata, Eiji;
Nagai, Noriaki

Publication type:

Article

Therapeutic Effects of Hydrogel Formulations Incorporating Troxipide Nanoparticles on Oral Mucositis in Hamsters.

Published in:

Drug Design, Development & Therapy, 2023, v. 17, p. 3349, doi. 10.2147/DDDT.S433776

By:

Kadowaki, Reita;
Ogata, Fumihiko;
Nishida, Miku;
Komatsu, Miri;
Otake, Hiroko;
Nakazawa, Yosuke;
Yamamoto, Naoki;
Kawasaki, Naohito;
Nagai, Noriaki

Publication type:

Article

Role of mucoadhesive agent in ocular delivery of ganciclovir microemulsion: cytotoxicity evaluation in vitro and ex vivo.

Published in:

International Ophthalmology, 2023, v. 43, n. 4, p. 1153, doi. 10.1007/s10792-022-02514-z

By:

Choudhari, Manisha;
Nayak, Kritika;
Nagai, Noriaki;
Nakazawa, Yosuke;
Khunt, Dignesh;
Misra, Manju

Publication type:

Article

HSP90 inhibitors promote cell death by degrading Met and BCR::ABL1 in both imatinib-resistant and -sensitive chronic myeloid leukemia cells.

Published in:

Future Journal of Pharmaceutical Sciences, 2025, v. 11, n. 1, p. 1, doi. 10.1186/s43094-025-00767-w

By:

Tsubaki, Masanobu;
Matsuo, Taira;
Komori, Rie;
Nagai, Noriaki;
Yamamoto, Tetsushi;
Nishida, Shozo

Publication type:

Article

Ferulic Acid Suppresses Amyloid β Production in the Human Lens Epithelial Cell Stimulated with Hydrogen Peroxide.

Published in:

BioMed Research International, 2017, v. 2017, p. 1, doi. 10.1155/2017/5343010

By:

Nagai, Noriaki;
Kotani, Sachiyo;
Mano, Yu;
Ueno, Akina;
Ito, Yoshimasa;
Kitaba, Toshio;
Takata, Takumi;
Fujii, Noriko

Publication type:

Article

Transdermal System Based on Solid Cilostazol Nanoparticles Attenuates Ischemia/Reperfusion-Induced Brain Injury in Mice.

Published in:

Nanomaterials (2079-4991), 2021, v. 11, n. 4, p. 1009, doi. 10.3390/nano11041009

By:

Otake, Hiroko;
Yamaguchi, Mizuki;
Ogata, Fumihiko;
Deguchi, Saori;
Yamamoto, Naoki;
Sasaki, Hiroshi;
Kawasaki, Naohito;
Nagai, Noriaki;
Liopo, Anton Valeri;
Derry, Paul J.

Publication type:

Article

Therapeutic Potential of a Combination of Magnesium Hydroxide Nanoparticles and Sericin for Epithelial Corneal Wound Healing.

Published in:

Nanomaterials (2079-4991), 2019, v. 9, n. 5, p. 768, doi. 10.3390/nano9050768

By:

Nagai, Noriaki;
Iwai, Yoshie;
Deguchi, Saori;
Otake, Hiroko;
Kanai, Kazutaka;
Okamoto, Norio;
Shimomura, Yoshikazu

Publication type:

Article

Pharmacological Behavior of Propylene Glycol/Polyvinyl Alcohol Hydrogel Incorporating Indomethacin Nanocrystals in the Skin.

Published in:

Gels (2310-2861), 2025, v. 11, n. 4, p. 251, doi. 10.3390/gels11040251

By:

Otake, Hiroko;
Ogata, Fumihiko;
Nakazawa, Yosuke;
Misra, Manju;
Tsubaki, Masanobu;
Kawasaki, Naohito;
Nagai, Noriaki

Publication type:

Article

Enhancement of Amyloid β1–43 Production in the Lens Epithelium of Japanese Type 2 Diabetic Patients.

Published in:

Biomedicines, 2020, v. 8, n. 4, p. 87, doi. 10.3390/biomedicines8040087

By:

Mano, Yu;
Otake, Hiroko;
Shibata, Teppei;
Kubo, Eri;
Sasaki, Hiroshi;
Nagai, Noriaki

Publication type:

Article

CD44v, S1PR1, HER3, MET and cancer‐associated amino acid transporters are promising targets for the pancreatic cancers characterized using mAb.

Published in:

FEBS Open Bio, 2025, v. 15, n. 5, p. 867, doi. 10.1002/2211-5463.13963

By:

Nakano, Takashi;
Okita, Kouki;
Okazaki, Shogo;
Yoshimoto, Soshi;
Masuko, Sachiko;
Yagi, Hideki;
Kato, Kazunori;
Tomioka, Yoshihisa;
Imai, Kenichi;
Hamada, Yoichi;
Masuko, Kazue;
Shimada‐Takaura, Kayoko;
Nagai, Noriaki;
Saya, Hideyuki;
Arai, Tomio;
Ishiwata, Toshiyuki;
Masuko, Takashi

Publication type:

Article

Involvement of Interleukin 18 in Cataract Development in Hereditary Cataract UPL Rats.

Published in:

Journal of Biochemistry, 2007, v. 142, n. 5, p. 597, doi. 10.1093/jb/mvm168

By:

Nagai, Noriaki;
Ito, Yoshimasa;
Okamura, Haruki

Publication type:

Article

N , N -Diethyl-3-toluamide Formulation Based on Ethanol Containing 0.1% 2-Hydroxypropyl-β-cyclodextrin Attenuates the Drug's Skin Penetration and Prolongs the Repellent Effect without Stickiness.

Published in:

Molecules, 2022, v. 27, n. 10, p. 3174, doi. 10.3390/molecules27103174

By:

Nagai, Noriaki;
Kawaguchi, Mayu;
Minami, Misa;
Matsumoto, Kana;
Sasabe, Tatsuji;
Nobuhara, Kenji;
Matsubara, Akira

Publication type:

Article

Degradation of connexin 50 protein causes waterclefts in human lens.

Published in:

Open Medicine, 2020, v. 15, n. 1, p. 1163, doi. 10.1515/med-2020-0249

By:

Yosuke Nakazawa;
Teppei Shibata;
Noriaki Nagai;
Eri Kubo;
Hiroomi Tamura;
Hiroshi Sasaki

Publication type:

Article

Enhancement of therapeutic efficacy of Brinzolamide for Glaucoma by nanocrystallization and tyloxapol addition.

Published in:

Journal of Pharmaceutical Health Care & Sciences, 2024, v. 10, n. 1, p. 1, doi. 10.1186/s40780-024-00375-5

By:

Masuda, Shuya;
Yano, Shiho;
Tadokoro, Tomohisa;
Otake, Hiroko;
Nagai, Noriaki

Publication type:

Article

Neokestose suppresses the increase in plasma glucose caused by oral administration of sucrose in a streptozotocin‑induced diabetic rat.

Published in:

Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-67458-z

By:

Sato, Kanta;
Deguchi, Saori;
Nagai, Noriaki;
Yamamoto, Tetsushi;
Mitamura, Kuniko;
Taga, Atsushi

Publication type:

Article

Semiquantitative analysis of protein expression in heated rat lens using shotgun proteomics.

Published in:

Molecular Medicine Reports, 2025, v. 31, n. 1, p. N.PAG, doi. 10.3892/mmr.2024.13391

By:

Otake, Hiroko;
Masuda, Shuya;
Yamamoto, Tetsushi;
Miyata, Yoshiki;
Nakazawa, Yosuke;
Yamamoto, Naoki;
Taga, Atsushi;
Sasaki, Hiroshi;
Nagai, Noriaki

Publication type:

Article

Hesperetin treatment attenuates glycation of lens proteins and advanced‑glycation end products generation.

Published in:

Molecular Medicine Reports, 2023, v. 27, n. 5, p. N.PAG, doi. 10.3892/mmr.2023.12990

By:

Doki, Yuri;
Nakazawa, Yosuke;
Morishita, Naoki;
Endo, Shin;
Nagai, Noriaki;
Yamamoto, Naoki;
Tamura, Hiroomi;
Funakoshi-Tago, Megumi

Publication type:

Article

Function of mitochondrial cytochrome c oxidase is enhanced in human lens epithelial cells at high temperatures.

Published in:

Molecular Medicine Reports, 2023, v. 27, n. 1, p. N.PAG

By:

Takeda, Shun;
Yamamoto, Naoki;
Nagai, Noriaki;
Hiramatsu, Noriko;
Deguchi, Saori;
Hatsusaka, Natsuko;
Kubo, Eri;
Sasaki, Hiroshi

Publication type:

Article

Retinal proteomic evaluation of rats following streptozotocin-injection using shotgun proteomics.

Published in:

Molecular Medicine Reports, 2020, v. 21, n. 1, p. 379, doi. 10.3892/mmr.2019.10801

By:

Otake, Hiroko;
Yamamoto, Tetushi;
Deguchi, Saori;
Taga, Atushi;
Nagai, Noriaki

Publication type:

Article

Changes in mitochondrial cytochrome c oxidase mRNA levels with cataract severity in lens epithelia of Japanese patients.

Published in:

Molecular Medicine Reports, 2019, v. 19, n. 6, p. 5464, doi. 10.3892/mmr.2019.10214

By:

Nagai, Noriaki;
Mano, Yu;
Otake, Hiroko;
Shibata, Teppei;
Kubo, Eri;
Sasaki, Hiroshi

Publication type:

Article

Effect of hesperetin derivatives on the development of selenite-induced cataracts in rats.

Published in:

Molecular Medicine Reports, 2018, v. 18, n. 1, p. 1043, doi. 10.3892/mmr.2018.9045

By:

Nakazawa, Yosuke;
Pauze, Martin;
Fukuyama, Kazuya;
Nagai, Noriaki;
Funakoshi-Tago, Megumi;
Sugai, Takeshi;
Tamura, Hiroomi

Publication type:

Article

Development of Sustained-Release Ophthalmic Formulation Based on Tranilast Solid Nanoparticles.

Published in:

Materials (1996-1944), 2020, v. 13, n. 7, p. 1675, doi. 10.3390/ma13071675

By:

Minami, Misa;
Seiriki, Ryotaro;
Otake, Hiroko;
Nakazawa, Yosuke;
Kanai, Kazutaka;
Tanino, Tadatoshi;
Nagai, Noriaki

Publication type:

Article