Gonadotropin intrauterin inseminasyon uygulanan açıklanamayan infertilite hastalarında gebeliğe etki eden prediktif faktörler.

ATALAY, Aysegul; YILDIRIM, Gonca; AYDIN, Alev

Aim: The aim of this study was to contribute to the reorganization of the treatment scheme in patients with unexplained infertility who underwent COH IUI by determining the effect of some predictive factors on pregnancy rates. Material and Methods: In our study, medical records of 431 patients and a total of 874 cycles who applied to the Infertility Clinic of Kanuni Sultan Süleyman Training and Research Hospital between January 2007 and July 2014 and were diagnosed with unexplained infertility and met the inclusion criteria were retrospectively analyzed. Males with a total progressive motile sperm count of less than 10 million and a body mass index of 30kg/m2 were excluded from the study. All patients underwent IUI 36 hours after induction with gonadotropins and assisted ovulation with HCG. The primary outcome measure was the pregnancy rate. The age of the females and males, infertility type, the duration of infertility, BMI, FSH and estradiol levels on the third day of menstruation, and antral follicle count were determined as predictive factors. Results: A total of 88 pregnancies were achieved in 431 couples in 874 cycles ( .4-.06 per cycles). Lojistik regresyon analizi yapılan prediktif faktörler içinde kadının yașı (10 million. In addition, there are many studies in which no significant difference was observed in pregnancy rates when FSH and clomiphene citrate were compared as induction methods. Therefore, similarly successful results could be obtained with CC treatment instead of FSH treatment, due to its high cost, OHSS risk and high risk of multiple pregnancy.

HIGH-risk pregnancy; OVARIAN follicle; LOGISTIC regression analysis; FERTILITY clinics; BODY mass index; INDUCED ovulation

Jinekoloji-Obstetrik & Neonatoloji Tip Dergisi, 2024, Vol 21, Issue 4, p301

1304-5512

Academic Journal

10.38136/jgon.1491587