Primary Hyperparathyroidism with Extensive Brown Tumors and Multiple Fractures in a 20-Year-Old Woman.

Ju Hee Choi; Kyoung Jin Kim; Ye Jin Lee; Sun Hwa Kim; Sin Gon Kim; Dong Seop Choi; Nam Hoon Kim; Kwang Yoon Jung

A brown tumor is a benign fibrotic, erosive bony lesion caused by localized, rapid osteoclastic turnover, resulting from hyperparathyroidism. Although brown tumors are one of the most pathognomonic signs of primary hyperparathyroidism, they are rarely seen in clinical practice. In this report, we present a case of 20-year-old woman with recurrent fractures and bone pain. FMain digital radiographs of the affected bones revealed multiple erosive bone tumors, which were finally diagnosed as brown tumors associated with primary hyperparathyroidism due to a parathyroid adenoma. This case shows that multiple, and clinically severe form of brown tumors can even occur in young patients.

BONE cancer; HYPERPARATHYROIDISM

Endocrinology & Metabolism, 2015, Vol 30, Issue 4, p614

2093-596X

Academic Journal

10.3803/EnM.2015.30.4.614