Introduction: The academic performance of medical students is negatively impacted by poor sleep quality and high levels of daily stress, which can result in anxiety, depression, suicidal thoughts, alcohol and substance misuse, and interpersonal problems. Objective: To determine the prevalence of poor sleep and its association with self-perceived stress among medical students of tertiary care hospital of district Shahdol (MP). Methods: The study provides the evidence of high prevalence of poor quality of sleep (44.6%). among the medical students & also the level of perceived stress which is alarmingly high with 67.4% has moderate stress and around 14.2% has high stress level. Results: Out of 348 students about 332 completed and returned the online proforma. The mean age of participants was 21.35 years. The study provides the evidence of high prevalence of poor quality of sleep (44.6%). among the medical students & also the level of perceived stress which is alarmingly high with 67.4% has moderate stress and around 14.2% has high stress level. Conclusions: Despite the medical students’ generally poor sleep quality and significant levels of reported stress. Students should get instruction in relaxation techniques, behavioural modifications, and sleep information as part of their curriculum.