Comparative evaluation of Levobupivacaine alone and Levobupivacaine with Dexmedetomidine as an adjuvant in Brachial plexus block for upper arm surgery.

Gupta, Rahul Ranjan; Arora, Sparsh; Kaur, Gagandeep; Shrivastava, Raj Krishna

Background: Brachial plexus block (BPB) provides effective analgesia for upper limb surgeries. Levobupivacaine, a longacting local anesthetic, is commonly used in BPB. This study aims to compare the efϔicacy and safety of Levobupivacaine alone versus Levobupivacaine with Dexmedetomidine as an adjuvant. Methods: In this prospective, randomized controlled trial, adult patients (18-65 years) undergoing elective upper arm surgeries were divided into two groups: Group B (Levobupivacaine alone) and Group D(Levobupivacaine with Dexmedetomidine). The BPB was performed using an ultrasound-guided technique. Primary outcomes included duration of analgesia, Visual Analog Scale (VAS) scores for analgesia, hemodynamic parameters, and sedation levels. Results: Group D showed a signiϔicantly longer duration of analgesia (565.2 ± 38.6 minutes) compared to Group B (243.7 ± 42.9 minutes) (p < 0.05). VAS scores were signiϔicantly better in Group D, with 90% reporting good analgesia versus 44% in Group B. Hemodynamic stability was similar in both groups, while sedation scores were higher in Group D, particularly in light and deep sedation categories. Conclusion: The combination of Levobupivacaine and Dexmedetomidine in BPB enhances the duration and quality of analgesia without compromising hemodynamic stability, offering potential beneϔits for postoperative pain management in upper arm surgeries.

POSTOPERATIVE pain treatment; BRACHIAL plexus block; VISUAL analog scale; LOCAL anesthetics; EXECUTIVES

Pravara Medical Review, 2024, Vol 16, Issue 3, p60

0975-0533

Academic Journal

10.36848/PMR/2024/90000.90099