Comparative retrospective study of post operative CSF leak in endoscopic endonasal transsphenoidal pituitary surgery with and without fibrin glue.

Sindhu, Kapil; Gupta, Vartika; Agarwal, Yogesh; Agarwal, Manoj; Gupta, Pankaj; Chauhan, Anchal

Aim: Comparative Retrospective study of post operative in Endoscopic endonasal transsphenoidal pituitary surgery without and with fibrin glue. Materials and Methods: A retrospective study was done at the Department of Neurosurgery of MGH with the approval of the institutional ethics committee. The study comprised all patients who was planned for surgical removal of pituitary adenoma using Endoscopic endonasal transsphenoidal approach. We gathered data about the demographic and clinical features of patients, the percentage of cerebrospinal fluid leakage post surgery, and the specific surgical method used for repairing the leakage. Results: The average age at the time of surgery was 51.23±6.32 years. Postoperative cerebrospinal fluid (CSF) leakage was reported in 52 individuals, representing 12.25% of all cases. Micro and macro adenoma was reported in 6.55% and 93.45% of the subjects respectively. High and low flow leakage was reported in 13.95% and 86.05% of the subjects respectively. Mortality was found in 1.14% of the subjects. Conclusion: Fibrin glue repair treatments are commonly used and effective methods for treating cerebrospinal fluid (CSF) leakage via the nose during endoscopic endonasal transsphenoidal operations. Every patient's treatment plan should be customized to suit their individual requirements.

CEREBROSPINAL fluid leak; FIBRIN tissue adhesive; CEREBROSPINAL fluid; PITUITARY tumors; NEUROSURGERY

Pravara Medical Review, 2024, Vol 16, Issue 3, p52

0975-0533

Academic Journal

10.36848/PMR/2024/90000.90060