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- Title
Association of serum PD-L1 and IGFBP-2 levels with prognosis in patients with esophageal carcinoma.
- Authors
Yun-Kui Huo; Xiu-Wen Yan; Ru-Xiong Bai; Fu Liu
- Abstract
This study investigates the prognostic value of serum biomarkers PD-L1 and IGFBP-2 in patients with esophageal carcinoma. It finds a significant positive correlation between these biomarkers and established tumor markers CEA and CYFRA21-1. The 3-year survival rate for the patient cohort was 45.10%, with deceased patients showing significantly higher levels of PD-L1 and IGFBP-2. ROC analysis indicates a strong predictive value for these biomarkers, with combined use potentially enhancing diagnostic accuracy. Kaplan-Meier curves reveal lower survival rates for patients with high biomarker expression. The study suggests that PD-L1 and IGFBP-2 could be valuable for clinical management and prognostic evaluation of esophageal carcinoma patients.
- Subjects
TUMOR markers; SURVIVAL rate; PROGRAMMED death-ligand 1; PROGNOSIS; BIOMARKERS
- Publication
Pakistan Journal of Pharmaceutical Sciences, 2024, Vol 37, Issue 6, p1315
- ISSN
1011-601X
- Publication type
Academic Journal
- DOI
10.36721/PJPS.2024.37.6.REG.1315-1321.1