Works matching DE "IMMUNE checkpoint proteins"

Results: 5000

Engineered immunologic niche monitors checkpoint blockade response and probes mechanisms of resistance.

Published in:

Immunomedicine, 2024, v. 4, n. 1, p. 1, doi. 10.1002/imed.1052

By:

Raghani, Ravi M.;
Urie, Russell R.;
Ma, Jeffrey A.;
Escalona, Guillermo;
Schrack, Ian A.;
DiLillo, Katarina M.;
Kandagatla, Pridvi;
Decker, Joseph T.;
Morris, Aaron H.;
Arnold, Kelly B.;
Jeruss, Jacqueline S.;
Shea, Lonnie D.

Publication type:

Article

Functions and mechanisms of lncRNAs in immune escape and their application in immunotherapy for colorectal cancer.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06732-8

By:

Zhang, Dechun;
Pei, Shaoxuan;
Feng, Zixuan;
Xia, Guangfeng

Publication type:

Article

GPR65 is a novel immune biomarker and regulates the immune microenvironment in lung adenocarcinoma.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1572757

By:

Zhou, Hanxu;
Chen, Zhi;
Gao, Shuang;
Lian, Chaoqun;
Hu, Junjie;
Lu, Jin;
Zhang, Lei

Publication type:

Article

Dissecting the multi-omics landscape of TEAD1 in hepatocellular carcinoma: cycle regulation and metastatic potential.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1567969

By:

Huai, Ruiping;
Mao, Canquan;
Xiong, Lili

Publication type:

Article

F-box proteins at the crossroads of ubiquitination and tumor immunity: regulatory networks and immunotherapy strategies.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1596344

By:

Dai, Mingzheng;
Chen, Shimin;
Wang, Yuanjing;
Fan, Jinxuan;
Pan, Xin;
Sang, Chenhui;
Liu, Yuchen;
Hu, Ming;
Ma, Leina;
Wang, Shasha

Publication type:

Article

Nanomaterials and immune checkpoint inhibitors in cancer immunotherapy: the synergistic innovation prospects.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1582774

By:

Chen, Jing;
Cheng, Xue

Publication type:

Article

Role of CD28+ PD-1+ Tc cells in immune response and prognosis prediction in hepatocellular carcinoma.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1576193

By:

Yang, Wuhan;
Pan, Teng;
Chen, Yaowen;
Guo, Hao;
Peng, Yaqi;
Wang, Chao;
Peng, Li;
Wang, Shubin

Publication type:

Article

Janus kinase and signal transducer and activator of transcription inhibitors in type 1 diabetes and immune checkpoint–related diabetes: current status and future perspectives.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1571247

By:

Su, Bowei;
Luan, Zhi-Lin;
Liu, Haixia;
Tuomilehto, Jaakko;
Ji, Xiaochen

Publication type:

Article

Immune checkpoint inhibitor-induced thyroiditis and its potential mechanisms.

Published in:

Frontiers in Endocrinology, 2025, p. 1, doi. 10.3389/fendo.2025.1584675

By:

Mao, Xueqian;
Mao, Chaoming;
Liu, Jiameng;
Wang, Xi;
Mao, Yufei

Publication type:

Article

Integrated pan-cancer analysis of ADM's role in prognosis, immune modulation and resistance.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1573250

By:

Liu, Yunhuan;
Zhou, Caicun

Publication type:

Article

GPR65 is a novel immune biomarker and regulates the immune microenvironment in lung adenocarcinoma.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1572757

By:

Zhou, Hanxu;
Chen, Zhi;
Gao, Shuang;
Lian, Chaoqun;
Hu, Junjie;
Lu, Jin;
Zhang, Lei

Publication type:

Article

A multi-type programmed cell death gene signature predicts survival and reveals therapeutic targets in osteosarcoma.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02944-y

By:

Wu, Chunyang

Publication type:

Article

An immune activator encapsulating PD-L1 siRNA for augmented immune checkpoint blockade immunotherapy through Zn2+ overload triggered pyroptosis.

Published in:

Journal of Nanobiotechnology, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12951-025-03521-9

By:

Gong, Liming;
Liu, Yanhong;
Feng, Jing;
Xiao, Congcong;
Liu, Chenfei;
Chen, Bohan;
Chen, Liqing;
Jin, Mingji;
Guan, Youyan;
Gao, Zhonggao;
Huang, Wei

Publication type:

Article

RIDDEN: Data-driven inference of receptor activity from transcriptomic data.

Published in:

PLoS Computational Biology, 2025, v. 21, n. 6, p. 1, doi. 10.1371/journal.pcbi.1013188

By:

Barsi, Szilvia;
Varga, Eszter;
Dimitrov, Daniel;
Saez-Rodriguez, Julio;
Hunyady, László;
Szalai, Bence

Publication type:

Article

Membrane-bound IL-15 co-expression powers a potent and persistent CD70-targeted TRuC T-cell therapy.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1609658

By:

Webb, Lindsay;
Lofgren, Michael;
Patterson, Troy;
Watt, Amy;
Lajoie, Jason;
Zieba, Adam;
Fleury, Michelle;
Liu, Erica;
Ding, Jian;
Tighe, Robert

Publication type:

Article

GPR65 is a novel immune biomarker and regulates the immune microenvironment in lung adenocarcinoma.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1572757

By:

Zhou, Hanxu;
Chen, Zhi;
Gao, Shuang;
Lian, Chaoqun;
Hu, Junjie;
Lu, Jin;
Zhang, Lei

Publication type:

Article

Pan-cancer analysis of TMED2: unraveling potential immune characteristics and prognostic value in cancer therapy.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1578627

By:

Wang, Zhuangzhi;
Sun, Changning;
Wang, Pengfei;
Lin, Shouyang;
Wu, Xiao;
Gu, Yuchao

Publication type:

Article

Drug repurposing of fostamatinib against cancer via potential cytotoxicity and immune checkpoint regulation.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1602189

By:

Hu, Maoqiong;
Yin, Renyi;
Deng, Kaifeng;
Xu, Ning

Publication type:

Article

The landscape and clinical impact of tumor-associated macrophages and PD-L1 in primary breast cancers and their brain metastases.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1598293

By:

Zimmer, Yannik Nicola;
Hanke, Benjamin;
Neyazi, Belal;
Rashidi, Ali;
Schaufler, Anna;
Dumitru, Claudia Alexandra;
Ignatov, Atanas;
Mawrin, Christian;
Sandalcioglu, I. Erol;
Stein, Klaus-Peter

Publication type:

Article

A question of TiME: how microenvironmental interactions shape response to immunotherapy in CLL and Richter Transformation.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1592574

By:

vom Stein, Alexander F.;
Nguyen, Phuong-Hien;
ten Hacken, Elisa

Publication type:

Article

A CD8+ T Cell Infiltration–Driven Prognostic Signature for Gastric Cancer: Bridging Tumor Immunity and Clinical Outcomes.

Published in:

International Journal of Genomics, 2025, v. 2025, p. 1, doi. 10.1155/ijog/6629479

By:

Qian, Yiting;
Sun, Bo;
Lai, Linying;
Xu, Fengying;
Liu, Ruilin;
Yang, Wenzhuo;
Zhao, Songyun

Publication type:

Article

《2025年美国肝病学会实践指导：肝细胞癌的预防、诊断和治疗（关键更新）》解读

Published in:

Journal of Clinical Hepatology / Linchuang Gandanbing Zazhi, 2025, v. 41, n. 5, p. 851, doi. 10.12449/JCH250509

By:

赵, 宇泽;
陈, 宇枭;
王, 科淳;
王, 明达;
杨, 田

Publication type:

Article

Myomedin variants developed for in vitro PD-L1 diagnostics in tissue samples of non-small cell lung carcinoma patients.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06699-6

By:

Petroková, Hana;
Mierzwicka, Joanna Maria;
Chakraborty, Prosenjit;
Rašková Kafková, Leona;
Vaculová, Jana;
Škarda, Jozef;
Fischer, Ondřej;
Kosztyu, Petr;
Kuchař, Milan;
Raška, Milan;
Malý, Petr

Publication type:

Article

The dynamics of brain T cell populations during the course of rasmussen encephalitis: from expansion to exhaustion.

Published in:

Journal of Neuroinflammation, 2025, v. 22, n. 1, p. 1, doi. 10.1186/s12974-025-03477-5

By:

Mair, Katharina M.;
Guggenberger, Victoria;
Verdú de Juan, Laia;
Köck, Ulrike;
Lassmann, Hans;
Liblau, Roland S.;
Bien, Christian G.;
Bauer, Jan

Publication type:

Article

Overcoming acquired immunotherapy resistance in non-small cell lung cancer using ginsenoside Rb1-loaded, peptide-enhanced exosome delivery systems.

Published in:

Journal of Nanobiotechnology, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12951-025-03456-1

By:

Jin, Xiangyuan;
Wuyun, Tanghesi;
Zhang, Yu;
Wang, Xiaohong;
Zhao, Ling

Publication type:

Article

Editorial: Immune cell therapy approaches targeting tumor microenvironment.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1628689

By:

Patnaik, Santosh K.;
Kalathil, Suresh Gopi

Publication type:

Article

PD-1 is conserved from sharks to humans: new insights into PD-1, PD-L1, PD-L2, and SHP-2 evolution.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1573492

By:

Kondo, Ryohei;
Kondo, Kohei;
Nabeshima, Kei;
Nishikimi, Akihiko;
Ishida, Yasumasa;
Shigeoka, Toshiaki;
Dijkstra, Johannes M.

Publication type:

Article

Body composition and checkpoint inhibitor treatment outcomes in advanced melanoma: a multicenter cohort study Open Access.

Published in:

JNCI: Journal of the National Cancer Institute, 2025, v. 117, n. 6, p. 1245, doi. 10.1093/jnci/djaf039

By:

Schuiveling, Mark;
Maat, Laurens S Ter;
Duin, Isabella A J Van;
Verheijden, Rik J;
Troenokarso, Max F;
Moeskops, Pim;
Verhoeff, Joost J C;
Elias, Sjoerd G;
Amsterdam, Wouter A C van;
Burgers, Femke;
Berkmortel, Franchette W P J Van den;
Boers-Sonderen, Marye J;
Boomsma, Martijn F;
Groot, Jan Willem De;
Haanen, John B A G;
Hospers, Geke A P;
Piersma, Djura;
Vreugdenhil, Gerard;
Westgeest, Hans M;
Kapiteijn, Ellen

Publication type:

Article

How many people in the US are eligible for and respond to checkpoint inhibitors: An empirical analysis.

Published in:

International Journal of Cancer, 2025, v. 156, n. 12, p. 2352, doi. 10.1002/ijc.35347

By:

Haslam, Alyson;
Olivier, Timothée;
Prasad, Vinay

Publication type:

Article

Proteogenomic characterization of molecular and cellular targets for treatment-resistant subtypes in locally advanced cervical cancers.

Published in:

Molecular Cancer, 2025, v. 24, n. 1, p. 1, doi. 10.1186/s12943-025-02373-z

By:

Hyeon, Do Young;
Nam, Dowoon;
Shin, Hye-Jin;
Jeong, Juhee;
Jung, Eunsoo;
Cho, Soo Young;
Shin, Dong Hoon;
Ku, Ja-Lok;
Baek, Hye Jung;
Yoo, Chong Woo;
Hong, Eun-Kyung;
Lim, Myong Cheol;
Lee, Sang-Jin;
Bae, Young-Ki;
Kim, Jong Kwang;
Bae, Jingi;
Choi, Wonyoung;
Kim, Su-Jin;
Back, Seunghoon;
Kang, Chaewon

Publication type:

Article

CircITSN2-miR-17-5p/20a-5p/20b-5p-PD-L1 regulatory network is a potential molecular mechanism of PD-L1 gene involving in immune response to IBDV.

Published in:

Avian Pathology, 2025, v. 54, n. 4, p. 512, doi. 10.1080/03079457.2025.2470754

By:

Jiang, Yi;
Tian, Yufei;
Han, Jianwei;
Wang, Xiangnan;
Zhang, Rui;
Xu, Xinxin;
Ma, Xiaoli;
Zhang, Wei;
Man, Chaolai

Publication type:

Article

Integrative Analysis of EPHX4 as a Novel Prognostic and Diagnostic Biomarker in Lung Adenocarcinoma.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 11, p. 5095, doi. 10.3390/ijms26115095

By:

Liu, Pengze;
Chen, Yutong

Publication type:

Article

Anti-Tumor Activities of Anti-Siglec-15 Chimeric Heavy-Chain Antibodies.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 11, p. 5068, doi. 10.3390/ijms26115068

By:

Cheng, Kexuan;
Guo, Jiazheng;
Li, Yating;
Kang, Qinglin;
Wang, Rong;
Luo, Longlong;
Wang, Wei;
Lu, Jiansheng

Publication type:

Article

Chemical and Enzymatic Synthesis of DisialylGb5 and Other Sialosides for Glycan Array Assembly and Evaluation of Siglec-Mediated Immune Checkpoint Inhibition.

Published in:

Molecules, 2025, v. 30, n. 11, p. 2264, doi. 10.3390/molecules30112264

By:

Liao, Kuo-Shiang;
Zhou, Yixuan;
Chung, Cinya;
Kung, Chih-Chuan;
Ren, Chien-Tai;
Wu, Chung-Yi;
Lou, Yi-Wei;
Chuang, Po-Kai;
Imre, Balázs;
Hsieh, Yves S. Y.;
Wong, Chi-Huey

Publication type:

Article

Immunotherapy Applications in Urology.

Published in:

Journal of Urological Surgery, 2025, v. 12, n. 2, p. 1, doi. 10.4274/jus.galenos.2025.2024-11-9

By:

Şenoğlu, Yusuf;
Şahin, Bahadır

Publication type:

Article

Comprehensive analysis of a palmitoylation-related prognostic signature in colorectal cancer: Implications for immune therapy and personalized treatment.

Published in:

Oncology Letters, 2025, v. 30, n. 1, p. N.PAG, doi. 10.3892/ol.2025.15096

By:

Wang, Xiaokang;
Li, Jian;
Wang, Zi;
Wu, Qingyun

Publication type:

Article

Unveiling fatty acid subtypes: immunometabolic interplay and therapeutic opportunities in gastric cancer.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1570873

By:

Liu, Huahuan;
Hu, Xin;
Zhang, Xiangnan;
Yao, Yanxin;
Wu, Liuxing;
Tian, Ye;
Dai, Hongji;
Chen, Kexin;
Liu, Ben

Publication type:

Article

Exosomes and immune modulation: implications for neuroblastoma immunotherapy.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1600062

By:

Morini, Martina;
Vitale, Chiara;
Ardito, Martina;
Dondero, Alessandra;
Cortese, Katia;
Bottino, Cristina;
Castriconi, Roberta

Publication type:

Article

GSDMD is a novel predictive biomarker for immunotherapy response: in the pan-cancer and single cell landscapes.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1570901

By:

Huang, Li Juan;
Chen, Feng;
Chen, Lin;
Zhan, Shi Tong;
Liu, Ming Min;
Xiang, Jiang Dong;
Zhang, Qin Yi;
Yang, Ye

Publication type:

Article

Agent-based modeling for personalized prediction of an experimental immune response to immunotherapeutic antibodies.

Published in:

PLoS ONE, 2025, v. 20, n. 6, p. 1, doi. 10.1371/journal.pone.0324618

By:

Matalon, Omri;
Perissinotto, Andrea;
Baruch, Kuti;
Braiman, Shai;
Geiger Maor, Anat;
Yoles, Eti;
Wilczynski, Ella;
Nevo, Uri;
Priel, Avner

Publication type:

Article

Impact of Doxorubicin and Docetaxel on Immune Checkpoint Expression in Colorectal Cancer: Insights into Chemotherapy Resistance Mechanisms.

Published in:

Biochemical Genetics, 2025, v. 63, n. 3, p. 2263, doi. 10.1007/s10528-024-10796-4

By:

Ahmadpour Youshanlui, Mahya;
Nasiri, Hadi;
Valedkarimi, Zahra;
Sadeghi, Mohammadreza;
Akbari, Morteza;
Motlagh Asghari, Kimia;
Jamali, Fereshteh;
Abdi, Deniz;
Mehramouz, Bahareh;
Rasi Bonab, Farnaz;
Baradaran, Behzad

Publication type:

Article

Multi-omics analysis identifies LANCL2 as a potential biomarker for the diagnosis and prognosis of gastric cancer.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-02745-x

By:

Fang, Xidong;
Liu, Mengxiao;
Ren, Qian;
Li, Renpeng;
Wu, Guozhi;
Yuan, Hao;
Zheng, Ya;
Gou, Xi;
Wang, Yuping;
Zhou, Yongning

Publication type:

Article

Immunohistochemical expression of PD1, LAG3, and CTLA4 in diffuse large B cell lymphoma, clinicopathological correlation, and prognostic value.

Published in:

Journal of the Egyptian National Cancer Institute, 2025, v. 37, n. 1, p. 1, doi. 10.1186/s43046-025-00303-0

By:

William, Madonna I.;
Tantawy, Dina A;
Elsergany, Alyaa R.;
El-Hawary, Amira K;
Yussif, Shaimaa M

Publication type:

Article

Association of PD-L1 Expression with Lymph Node Metastasis and Clinical Stage in Ampulla of Vater Cancer: An Observational Study.

Published in:

Cancer Management & Research, 2025, v. 17, p. 965, doi. 10.2147/CMAR.S513961

By:

Andrianto, Andrianto;
Rudiman, Reno;
Ruchimat, Tommy;
Lukman, Kiki;
Sulthana, Bambang Am Am Setya;
Purnama, Andriana;
Wijaya, Alma;
Primastari, Etis;
Nugraha, Prapanca

Publication type:

Article

SLAM receptors regulate immune checkpoints via SAP and EAT- 2 in rheumatoid arthritis: association with disease activity.

Published in:

Clinical Rheumatology, 2025, v. 44, n. 6, p. 2201, doi. 10.1007/s10067-025-07461-5

By:

Malekan, Mohammad;
Dozandeh-Jouybari, Armin;
Sadeghian, Najmeh;
Soltanshahi, Mohsen;
Azadeh, Hossein;
Ajami, Abolghasem;
Asgarian-Omran, Hossein;
Taghiloo, Saeid

Publication type:

Article

Circulating T cell atlas in Moyamoya disease: insights into immunopathogenesis of cerebrovascular disorders.

Published in:

Journal of Neuroinflammation, 2025, v. 22, n. 1, p. 1, doi. 10.1186/s12974-025-03479-3

By:

Liu, Chenglong;
Li, Junsheng;
Mou, Siqi;
Pang, Yuheng;
Chan, Liujia;
He, Qiheng;
Liu, Wei;
Zhao, Zhikang;
Zhang, Bojian;
Zheng, Zhiyao;
Sun, Wei;
Shi, Xiangjun;
Zhang, Qian;
Wang, Rong;
Zhang, Yan;
Wang, Wenjing;
Zhang, Dong;
Ge, Peicong

Publication type:

Article

Lysine‐specific demethylase 1 deletion reshapes tumour microenvironment to overcome acquired resistance to anti‐programmed death 1 therapy in liver cancer.

Published in:

Clinical & Translational Medicine, 2025, v. 15, n. 5, p. 1, doi. 10.1002/ctm2.70335

By:

Liang, Chen;
Ye, Mu;
Yu, Lei;
Zhang, Peng‐Fei;
Guo, Xiao‐Jun;
Meng, Xian‐Long;
Zeng, Hai‐Ying;
Hu, Shu‐Yang;
Zhang, Dao‐Han;
Sun, Qi‐Man;
Shen, Ying‐Hao;
Cai, Jia‐Bin;
Li, Shuang‐Qi;
Chen, Zhen;
Shi, Ying‐Hong;
Ke, Ai‐Wu;
Shi, Yujiang G.;
Zhou, Jian;
Fan, Jia;
Wu, Fei‐Zhen

Publication type:

Article

ALG3 as a prognostic biomarker and mediator of PD-1 blockade resistance in hepatocellular carcinoma.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1589153

By:

Tang, Pengju;
Han, Zhenwei;
Zhao, Yiming;
Xu, Tianxin;
Zhang, Yu;
Zhu, Lirong;
Song, Fei;
Gao, Cheng;
Gong, Jinbo;
Cheng, Ji;
Wang, Chenggui;
Wang, Tianlun;
Xu, Jie;
Wang, Yu;
Chen, Zhong

Publication type:

Article

Single-cell and bulk transcriptome analyses reveal elevated amino acid metabolism promoting tumor-directed immune evasion in colorectal cancer.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1575829

By:

Sun, Tianyue;
Chen, Yan;
Chen, Ying-Xuan

Publication type:

Article

Expression of PSMD14 in lung adenocarcinoma and its impact on immune cell infiltration and prognosis: a comprehensive analysis based on RNA and single-cell RNA sequencing.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1560693

By:

Zhang, Jing;
Sun, Bohao;
Lai, Jiabin;
Kong, Weike;
Wang, Nan;
Li, Panyuan;
Wu, Yichen;
Jiang, Zhaochang

Publication type:

Article