Works matching DE "DOUBLE-strand DNA breaks"

Results: 2082

PRDM9 drives the location and rapid evolution of recombination hotspots in salmonid fish.

Published in:

PLoS Biology, 2025, v. 23, n. 1, p. 1, doi. 10.1371/journal.pbio.3002950

By:

Raynaud, Marie;
Sanna, Paola;
Joseph, Julien;
Clément, Julie;
Imai, Yukiko;
Lareyre, Jean-Jacques;
Laurent, Audrey;
Galtier, Nicolas;
Baudat, Frédéric;
Duret, Laurent;
Gagnaire, Pierre-Alexandre;
de Massy, Bernard

Publication type:

Article

The mismatch repair and meiotic recombination endonuclease Mlh1-Mlh3 is activated by polymer formation and can cleave DNA substrates in trans.

Published in:

PLoS Biology, 2017, v. 15, n. 4, p. 1, doi. 10.1371/journal.pbio.2001164

By:

Manhart, Carol M.;
Ni, Xiaodan;
White, Martin A.;
Ortega, Joaquin;
Surtees, Jennifer A.;
Alani, Eric

Publication type:

Article

The Rapid Synthesis of Colibactin Warhead Model Compounds Using New Metal‐Free Photocatalytic Cyclopropanation Reactions Facilitates the Investigation of Biological Mechanisms.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 56, p. 1, doi. 10.1002/chem.202301713

By:

Bosveli, Artemis;
Griboura, Nefeli;
Kampouropoulos, Ioannis;
Kalaitzakis, Dimitris;
Montagnon, Tamsyn;
Vassilikogiannakis, Georgios

Publication type:

Article

Capturing a Pentacyclic Fragment‐Based Library Derived from Perophoramidine: Their Design, Synthesis and Evaluation as Anticancer Compounds by DNA Double‐Strand Breaks (DSB) and PARP‐1 Inhibition.

Published in:

Chemistry - A European Journal, 2022, v. 28, n. 63, p. 1, doi. 10.1002/chem.202202405

By:

Guha, Souvik;
Yussif El‐Deeb, Ibrahim;
Yadav, Shalini;
Das, Ranajit;
Dutta Dubey, Kshatresh;
Baruah, Mousumi;
Gremaud, Ludovic;
Sen, Subhabrata

Publication type:

Article

Unraveling and Overcoming Platinum Drug‐Resistant Cancer Tumors with DNA Nanostructures.

Published in:

Advanced Functional Materials, 2023, v. 33, n. 2, p. 1, doi. 10.1002/adfm.202208797

By:

Yu, Yingjie;
Zhang, Linghao;
Qin, Zhaohui;
Karges, Johannes;
Xiao, Haihua;
Su, Xin

Publication type:

Article

Poly-glycine–alanine exacerbates C9orf72 repeat expansion-mediated DNA damage via sequestration of phosphorylated ATM and loss of nuclear hnRNPA3.

Published in:

Acta Neuropathologica, 2020, v. 139, n. 1, p. 99, doi. 10.1007/s00401-019-02082-0

By:

Nihei, Yoshihiro;
Mori, Kohji;
Werner, Georg;
Arzberger, Thomas;
Zhou, Qihui;
Khosravi, Barham;
Japtok, Julia;
Hermann, Andreas;
Sommacal, Andreas;
Weber, Markus;
Kamp, Frits;
Nuscher, Brigitte;
Edbauer, Dieter;
Haass, Christian

Publication type:

Article

Post-Integrational DNA Repair of HIV-1 Is Associated with Activation of the DNA-PK and ATM Cellular Protein Kinases and Phosphorylation of Their Targets.

Published in:

Biochemistry (00062979), 2024, v. 89, n. 6, p. 1122, doi. 10.1134/S0006297924060117

By:

Anisenko, Andrey N.;
Nefedova, Anastasiia A.;
Kireev, Igor I.;
Gottikh, Marina B.

Publication type:

Article

Topology of Ubiquitin Chains in the Chromatosomal Environment of the E3 Ubiquitin Ligase RNF168.

Published in:

Biochemistry (00062979), 2023, v. 88, n. 12/13, p. 2063, doi. 10.1134/S000629792312009X

By:

Kudriaeva, Anna A.;
Yakubova, Lyudmila A.;
Saratov, George A.;
Vladimirov, Vasiliy I.;
Lipkin, Valeriy M.;
Belogurov Jr., Alexey A.

Publication type:

Article

Mechanisms of Secondary Leukemia Development Caused by Treatment with DNA Topoisomerase Inhibitors.

Published in:

Biochemistry (00062979), 2023, v. 88, n. 7, p. 892, doi. 10.1134/S0006297923070040

By:

Lomov, Nikolai A.;
Viushkov, Vladimir S.;
Rubtsov, Mikhail A.

Publication type:

Article

Rational Design of ssODN to Correct Mutations by Gene Editing.

Published in:

Biochemistry (00062979), 2022, v. 87, n. 5, p. 464, doi. 10.1134/S0006297922050078

By:

Volodina, Olga V.;
Anuchina, Arina A.;
Zainitdinova, Milyausha I.;
Evtushenko, Nadezhda A.;
Lavrov, Alexander V.;
Smirnikhina, Svetlana A.

Publication type:

Article

Cryopreserved Stem Cells Incur Damages Due To Terrestrial Cosmic Rays Impairing Their Integrity Upon Long-Term Storage.

Published in:

Cell Transplantation, 2022, v. 31, p. 1, doi. 10.1177/09636897211070239

By:

Rocheteau, P.;
Warot, G.;
Chapellier, M.;
Zampaolo, M.;
Chretien, F.;
Piquemal, F.

Publication type:

Article

Genomic hallmarks of endocrine therapy resistance in ER/PR+HER2- breast tumours.

Published in:

Communications Biology, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42003-025-07606-x

By:

Ghosh, Arnab;
Chaubal, Rohan;
Das, Chitrarpita;
Parab, Pallavi;
Das, Subrata;
Maitra, Arindam;
Majumder, Partha P.;
Gupta, Sudeep;
Biswas, Nidhan K.

Publication type:

Article

Toxoplasma gondii infection induces early host cell cycle arrest and DNA damage in primary human host cells by a MYR1-dependent mechanism.

Published in:

Communications Biology, 2024, v. 7, n. 1, p. 1, doi. 10.1038/s42003-024-07374-0

By:

Velásquez, Zahady D.;
Rojas-Baron, Lisbeth;
Conejeros, Iván;
Hermosilla, Carlos;
Taubert, Anja

Publication type:

Article

RNA-guided piggyBac transposition in human cells.

Published in:

Synthetic Biology (23977000), 2019, v. 4, n. 1, p. N.PAG, doi. 10.1093/synbio/ysz018

By:

Hew, Brian E;
Sato, Ryuei;
Mauro, Damiano;
Stoytchev, Ilko;
Owens, Jesse B

Publication type:

Article

An Expansion of the Endoplasmic Reticulum that Halts Autophagy is Permissive to Genome Instability.

Published in:

Contact (25152564), 2023, p. 1, doi. 10.1177/25152564231157706

By:

Lara-Barba, Eliana;
Torán-Vilarrubias, Alba;
Moriel-Carretero, María

Publication type:

Article

Next-generation mammalian genetics toward organism-level systems biology.

Published in:

NPJ Systems Biology & Applications, 2017, v. 3, n. 1, p. N.PAG, doi. 10.1038/s41540-017-0015-2

By:

Susaki, Etsuo A.;
Ukai, Hideki;
Ueda, Hiroki R.

Publication type:

Article

Association between papillary thyroid cancer and XRCC6 gene polymorphisms in the Turkish population.

Published in:

Turkish Journal of Medical Sciences, 2024, v. 54, n. 6, p. 1215, doi. 10.55730/1300-0144.5902

By:

AKGÜN, Egemen;
İÇDUYGU, Fadime MUTLU;
ŞENGÜL, Demet;
ALP, Ebru;
ALKANAT, Mehmet;
ÇEBİ, Ayşegül;
ÖZTÜRK, Tuncer

Publication type:

Article

Assessing breast cancer risk: Tailored surveillance and risk-reductive interventions.

Published in:

Medicine Today, 2024, v. 25, n. 9, p. 56

By:

OFRI, ADAM;
MOORE, KATRINA;
WARRIER, SANJAY

Publication type:

Article

Mathematical model of chromosomal dynamics during DNA double strand break repair in budding yeast.

Published in:

Biophysics & Physicobiology, 2022, v. 19, p. 1, doi. 10.2142/biophysico.bppb-v19.0012

By:

Shinjiro Nakahata;
Tetsushi Komoto;
Masashi Fujii;
Akinori Awazu

Publication type:

Article

Impacts of prolonged exposure to low concentration of titanium dioxide nanoparticles on cell cycle control and DNA repair.

Published in:

European Journal of Biological Research, 2022, v. 12, n. 4, p. 339, doi. 10.5281/zenodo.7487421

By:

Elzahed, Nada;
Kakarougkas, Andreas

Publication type:

Article

A game of musical chairs: Pro- and anti-resection factors compete for TOP BP1 binding after DNA damage.

Published in:

Journal of Cell Biology, 2017, v. 216, n. 3, p. 535, doi. 10.1083/jcb.201701038

By:

Shimada, Kenji;
Gasser, Susan M.

Publication type:

Article

Upregulated DNA Damage-Linked Biomarkers in Parkinson's Disease Model Mice.

Published in:

ASN Neuro (Sage Publications, Ltd.), 2023, p. 1, doi. 10.1177/17590914231152099

By:

Zeng, Fei;
Parker, Karsten;
Zhan, Yanqiang;
Miller, Matthew;
Zhu, Meng-Yang

Publication type:

Article

Upregulated DNA Damage-Linked Biomarkers in Parkinson's Disease Model Mice.

Published in:

ASN Neuro (Sage Publications, Ltd.), 2023, v. 15, p. 1, doi. 10.1177/17590914231152099

By:

Zeng, Fei;
Parker, Karsten;
Zhan, Yanqiang;
Miller, Matthew;
Zhu, Meng-Yang

Publication type:

Article

Synergistic Antitumor Effect of Combined Radiotherapy and Engineered Salmonella typhimurium in an Intracranial Sarcoma Mouse Model.

Published in:

Vaccines, 2023, v. 11, n. 7, p. 1275, doi. 10.3390/vaccines11071275

By:

Liu, Zhipeng;
Lim, Sa-Hoe;
Min, Jung-Joon;
Jung, Shin

Publication type:

Article

A direct role of RNA polymerase III and RNA in DNA homologous recombination.

Published in:

Molecular & Cellular Oncology, 2021, v. 8, n. 4, p. 1, doi. 10.1080/23723556.2021.1935173

By:

Liu, Sijie;
Kong, Daochun

Publication type:

Article

It takes three to the DNA damage response tango.

Published in:

Molecular & Cellular Oncology, 2021, v. 8, n. 2, p. 1, doi. 10.1080/23723556.2021.1881395

By:

Schlam-Babayov, Sapir;
Ziv, Yael;
Shiloh, Yosef

Publication type:

Article

Mapping the breakome reveals tight regulation on oncogenic super-enhancers.

Published in:

Molecular & Cellular Oncology, 2020, v. 7, n. 3, p. 1, doi. 10.1080/23723556.2019.1698933

By:

Oster, Sara;
Aqeilan, Rami I.

Publication type:

Article

Transcription-dependent DNA double-strand breaks and human disease.

Published in:

2020

By:

Cristini, Agnese;
Gromak, Natalia;
Sordet, Olivier

Publication type:

Opinion

Compartmentalized DNA repair: Rif1 S-acylation links DNA double-strand break repair to the nuclear membrane.

Published in:

2019

By:

Fontana, Gabriele A.;
Rass, Ulrich

Publication type:

Opinion

Genome instability triggered by the V(D)J recombination by-product.

Published in:

Molecular & Cellular Oncology, 2019, v. 6, n. 4, p. N.PAG, doi. 10.1080/23723556.2019.1610323

By:

Kirkham, Christopher M.;
Boyes, Joan

Publication type:

Article

A chromatin-based signalling mechanism directs the switch from mutagenic to error-free repair of DNA double strand breaks.

Published in:

Molecular & Cellular Oncology, 2019, v. 6, n. 4, p. N.PAG, doi. 10.1080/23723556.2019.1605820

By:

Bartke, Till;
Groth, Anja

Publication type:

Article

UBQLN4 promotes non-homologous end joining by repressing DNA end-resection.

Published in:

Molecular & Cellular Oncology, 2019, v. 6, n. 2, p. 1, doi. 10.1080/23723556.2019.1575692

By:

Jachimowicz, Ron D.;
Reinhardt, H. Christian

Publication type:

Article

The Cohesion complex maintains genome stability by preventing end joining of distant DNA ends in S phase.

Published in:

Molecular & Cellular Oncology, 2018, v. 5, n. 3, p. 1, doi. 10.1080/23723556.2016.1154123

By:

Gelot, Camille;
Guirouilh-Barbat, Josée;
Lopez, Bernard S.

Publication type:

Article

A TAD closer to ATM.

Published in:

2016

By:

Aymard, Francois;
Legube, Gaëlle

Publication type:

Opinion

PTH 缺失通过诱导肾脏细胞衰老和衰老相关分泌表型分子表达而加速肾脏纤维化.

Published in:

Progress in Modern Biomedicine, 2024, v. 24, n. 16, p. 3006, doi. 10.13241/j.cnki.pmb.2024.16.002

By:

刘星辰;
王璟;
刘博阳;
张娇;
刘王佳;
苗登顺

Publication type:

Article

上调 miR-216a-5p 通过靶向双特异性磷酸酶 10 抑制胃癌细胞自噬并增强放射敏感性.

Published in:

Progress in Modern Biomedicine, 2022, v. 22, n. 22, p. 4206, doi. 10.13241/j.cnki.pmb.2022.22.002

By:

尹建浩;
陈威;
王琼;
袁达伟;
朱琨;
李康;
线胤生;
张勇;
许刚

Publication type:

Article

PVCL-MnO<sub>2</sub> 纳米探针用于多形性胶质母细胞瘤的放疗增敏及 MRI 成像的实验研究.

Published in:

Progress in Modern Biomedicine, 2022, v. 22, n. 10, p. 1801, doi. 10.13241/j.cnki.pmb.2022.10.001

By:

贺美娟;
王毅晖;
余宏微;
范旭辉;
王悍

Publication type:

Article

The γ-H2AX foci as an indicator for double-stranded DNA breaks and response to ongoing chemotherapy in breast cancer women: a pilot study.

Published in:

European Review for Medical & Pharmacological Sciences, 2023, v. 27, n. 13, p. 6282

By:

AITMAGAMBETOVA, M.;
SMAGULOVA, G.;
SAKHANOVA, S.;
KEREYEVA, N.;
KOISHYBAEV, A.;
AMANZHOLKYZY, A.;
TULYAEVA, A.;
ZHOLMUKHAMEDOVA, D.;
KANDYGULOVA, G.;
IMANBAEV, N.;
DONAYEVA, A.;
ABDELAZIM, I. A.;
SAPARBAYEV, S.;
KHAMIDULLINA, Z.;
GUBASHEVA, G.

Publication type:

Article

PTEN expression in U251 glioma cells enhances their sensitivity to ionizing radiation by suppressing DNA repair capacity.

Published in:

European Review for Medical & Pharmacological Sciences, 2019, v. 23, n. 23, p. 10453

By:

LI, H. -L.;
WANG, C. -Y.;
FU, J.;
YANG, X. -J.;
SUN1, Y.;
SHAO, Y. -H.;
ZHANG, L. -H.;
YANG, X. -M.;
ZHANG, X. -L.;
LIN, J.

Publication type:

Article

God does not play dice, and neither does CRISPR/Cas9.

Published in:

National Science Review, 2019, v. 6, n. 3, p. 393, doi. 10.1093/nsr/nwy156

By:

Long, Chengzu

Publication type:

Article

Early onset senescence and cognitive impairment in a murine model of repeated mTBI.

Published in:

Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01190-x

By:

Schwab, Nicole;
Ju, YoungJun;
Hazrati, Lili-Naz

Publication type:

Article

BK polyomavirus nephropathy with systemic viral spread: Whole genome sequencing data from a fatal case of BKPyV infection.

Published in:

Transplant Infectious Disease, 2020, v. 22, n. 2, p. 1, doi. 10.1111/tid.13269

By:

Roy, Sanjeet;
Mieczkowski, Piotr A.;
Weida, Carol;
Huo, Jeffrey;
Roehrs, Philip;
Singh, Harsharan K.;
Nickeleit, Volker

Publication type:

Article

EVALUATION THE ROLE OF VITAMIN C AS A RADIATION PROTECTIVE AGENT USING γ -H2AX FOR SIGNALING OF DNA DAMAGE ON IRRADIATED MICE TESTIS.

Published in:

Periódico Tchê Química, 2020, v. 17, n. 36, p. 128, doi. 10.52571/ptq.v17.n36.2020.144_periodico36_pgs_128_139.pdf

By:

ALANI, Ekhlas A.;
ALMUSAWI, Mustafa S.;
MAHDI, Amar H.

Publication type:

Article

Taking a Bad Turn: Compromised DNA Damage Response in Leukemia.

Published in:

Cells (2073-4409), 2017, v. 6, n. 2, p. 11, doi. 10.3390/cells6020011

By:

Nilles, Nadine;
Fahrenkrog, Birthe

Publication type:

Article

Pyrazolo[3,4- d ]pyrimidine Tyrosine Kinase Inhibitors Induce Oxidative Stress in Patient-Derived Glioblastoma Cells.

Published in:

Brain Sciences (2076-3425), 2021, v. 11, n. 7, p. 884, doi. 10.3390/brainsci11070884

By:

Kostić, Ana;
Jovanović Stojanov, Sofija;
Podolski-Renić, Ana;
Nešović, Marija;
Dragoj, Miodrag;
Nikolić, Igor;
Tasić, Goran;
Schenone, Silvia;
Pešić, Milica;
Dinić, Jelena

Publication type:

Article

Senescence-like Phenotype After Chronic Exposure to Isoproterenol in Primary Quiescent Immune Cells.

Published in:

Biomolecules (2218-273X), 2024, v. 14, n. 12, p. 1528, doi. 10.3390/biom14121528

By:

Laumann, Michael;
Palombo, Philipp;
Fieres, Judy;
Thomas, Mara;
Saretzki, Gabriele;
Bürkle, Alexander;
Moreno-Villanueva, Maria

Publication type:

Article

When Chromatin Decondensation Affects Nuclear γH2AX Foci Pattern and Kinetics and Biases the Assessment of DNA Double-Strand Breaks by Immunofluorescence.

Published in:

Biomolecules (2218-273X), 2024, v. 14, n. 6, p. 703, doi. 10.3390/biom14060703

By:

Granzotto, Adeline;
El Nachef, Laura;
Restier-Verlet, Juliette;
Sonzogni, Laurène;
Al-Choboq, Joëlle;
Bourguignon, Michel;
Foray, Nicolas

Publication type:

Article

Response of Fibroblasts from Menkes' and Wilson's Copper Metabolism-Related Disorders to Ionizing Radiation: Influence of the Nucleo-Shuttling of the ATM Protein Kinase.

Published in:

Biomolecules (2218-273X), 2023, v. 13, n. 12, p. 1746, doi. 10.3390/biom13121746

By:

El Nachef, Laura;
Al-Choboq, Joëlle;
Bourguignon, Michel;
Foray, Nicolas

Publication type:

Article

Nano-Architecture of Persistent Focal DNA Damage Regions in the Minipig Epidermis Weeks after Acute γ-Irradiation.

Published in:

Biomolecules (2218-273X), 2023, v. 13, n. 10, p. 1518, doi. 10.3390/biom13101518

By:

Scherthan, Harry;
Geiger, Beatrice;
Ridinger, David;
Müller, Jessica;
Riccobono, Diane;
Bestvater, Felix;
Port, Matthias;
Hausmann, Michael

Publication type:

Article

The Hop2-Mnd1 Complex and Its Regulation of Homologous Recombination.

Published in:

Biomolecules (2218-273X), 2023, v. 13, n. 4, p. 662, doi. 10.3390/biom13040662

By:

Tsubouchi, Hideo

Publication type:

Article