Works matching AU Hussack, Greg
Results: 32
Role of the non‐hypervariable FR3 D‐E loop in single‐domain antibody recognition of haptens and carbohydrates.
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- Journal of Molecular Recognition, 2019, v. 32, n. 11, p. 1, doi. 10.1002/jmr.2805
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- Article
In vivo brain delivery of BBB-enabled iduronate 2-sulfatase in rats.
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- Fluids & Barriers of the CNS, 2025, v. 22, n. 1, p. 1, doi. 10.1186/s12987-024-00617-6
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- Article
Stability-Diversity Tradeoffs Impose Fundamental Constraints on Selection of Synthetic Human V<sub>H</sub>/V<sub>L</sub> Single-Domain Antibodies from In Vitro Display Libraries.
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- Frontiers in Immunology, 2017, p. 1, doi. 10.3389/fimmu.2017.01759
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A Novel Affinity Tag, ABTAG, and Its Application to the Affinity Screening of Single-Domain Antibodies Selected by Phage Display.
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- Frontiers in Immunology, 2017, p. 1, doi. 10.3389/fimmu.2017.01406
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A Novel Antigen Design Strategy to Isolate Single‐Domain Antibodies that Target Human Nav1.7 and Reduce Pain in Animal Models.
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- Advanced Science, 2024, v. 11, n. 40, p. 1, doi. 10.1002/advs.202405432
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- Article
Camelid single-domain antibodies raised by DNA immunization are potent inhibitors of EGFR signaling.
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- Biochemical Journal, 2019, v. 476, n. 1, p. 39, doi. 10.1042/BCJ20180795
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Modulating antibody‐dependent cellular cytotoxicity of epidermal growth factor receptor‐specific heavy‐chain antibodies through hinge engineering.
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- Immunology & Cell Biology, 2019, v. 97, n. 6, p. 526, doi. 10.1111/imcb.12238
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Editorial: Single-domain antibodies—biology, engineering and emerging applications, volume II.
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- Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1537054
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Epitope mapping of a blood–brain barrier crossing antibody targeting the cysteine-rich region of IGF1R using hydrogen-exchange mass spectrometry enabled by electrochemical reduction.
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- Journal of Biochemistry, 2023, v. 173, n. 2, p. 95, doi. 10.1093/jb/mvac088
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Structure of a Therapeutic Antibody in Complex with MUC16 Reveals a Conformational Epitope Influenced by Antigen Glycosylation.
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- FASEB Journal, 2022, v. 36, p. N.PAG, doi. 10.1096/fasebj.2022.36.S1.R5166
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- Article
Targeting insulin‐like growth factor‐1 receptor (IGF1R) for brain delivery of biologics.
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- FASEB Journal, 2022, v. 36, n. 3, p. 1, doi. 10.1096/fj.202101644R
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- Article
Serum albumin‐binding V<sub>H</sub>Hs with variable pH sensitivities enable tailored half‐life extension of biologics.
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- FASEB Journal, 2020, v. 34, n. 6, p. 8155, doi. 10.1096/fj.201903231R
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- Article
Arsenal of nanobodies shows broad-spectrum neutralization against SARS-CoV-2 variants of concern in vitro and in vivo in hamster models.
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- Communications Biology, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s42003-022-03866-z
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Structure-guided design of a potent Clostridioides difficile toxin A inhibitor.
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- Frontiers in Microbiology, 2023, v. 14, p. 1, doi. 10.3389/fmicb.2023.1110541
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- Article
A Rational Engineering Strategy for Designing Protein A-Binding Camelid Single-Domain Antibodies.
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- PLoS ONE, 2016, v. 11, n. 9, p. 1, doi. 10.1371/journal.pone.0163113
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Single-Domain Antibodies Represent Novel Alternatives to Monoclonal Antibodies as Targeting Agents against the Human Papillomavirus 16 E6 Protein.
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- International Journal of Molecular Sciences, 2019, v. 20, n. 9, p. 2088, doi. 10.3390/ijms20092088
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Brain Delivery of IGF1R5, a Single-Domain Antibody Targeting Insulin-like Growth Factor-1 Receptor.
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- Pharmaceutics, 2022, v. 14, n. 7, p. N.PAG, doi. 10.3390/pharmaceutics14071452
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Targeting surface-layer proteins with single-domain antibodies: a potential therapeutic approach against Clostridium difficile-associated disease.
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- Applied Microbiology & Biotechnology, 2015, v. 99, n. 20, p. 8549, doi. 10.1007/s00253-015-6594-1
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- Article
An update on antibody-based immunotherapies for Clostridium difficile infection.
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- Clinical & Experimental Gastroenterology, 2016, v. 9, p. 209, doi. 10.2147/CEG.S84017
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Isolation of TGF-ß-neutralizing single-domain antibodies of predetermined epitope specificity using next-generation DNA sequencing.
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- PEDS: Protein Engineering, Design & Selection, 2016, v. 29, n. 10, p. 439, doi. 10.1093/protein/gzw043
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Identification of cross-reactive single-domain antibodies against serum albumin using next-generation DNA sequencing.
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- PEDS: Protein Engineering, Design & Selection, 2015, v. 28, n. 10, p. 379, doi. 10.1093/protein/gzv039
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- Article
Protease-resistant single-domain antibodies inhibit Campylobacter jejuni motility.
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- PEDS: Protein Engineering, Design & Selection, 2014, v. 27, n. 6, p. 191, doi. 10.1093/protein/gzu011
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A VL single-domain antibody library shows a high-propensity to yield non-aggregating binders †.
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- PEDS: Protein Engineering, Design & Selection, 2012, v. 25, n. 6, p. 313, doi. 10.1093/protein/gzs014
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Multivalent Anchoring and Oriented Display of Single-Domain Antibodies on Cellulose.
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- Sensors (14248220), 2009, v. 9, n. 7, p. 5351, doi. 10.3390/s90705351
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- Article
Defining the epitope of a blood–brain barrier crossing single domain antibody specific for the type 1 insulin-like growth factor receptor.
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- Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-83198-w
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Isolation and characterization of camelid single-domain antibodies against HER2.
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- BMC Research Notes, 2018, v. 11, n. 1, p. N.PAG, doi. 10.1186/s13104-018-3955-8
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Neutralization of Clostridium difficile toxin B with V<sub>H</sub>H-Fc fusions targeting the delivery and CROPs domains.
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- PLoS ONE, 2018, v. 13, n. 12, p. 1, doi. 10.1371/journal.pone.0208978
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Outer membrane vesicles as a platform for the discovery of antibodies to bacterial pathogens.
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- Applied Microbiology & Biotechnology, 2024, v. 108, n. 1, p. 1, doi. 10.1007/s00253-024-13033-5
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Outer membrane vesicles as a platform for the discovery of antibodies to bacterial pathogens.
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- Applied Microbiology & Biotechnology, 2024, v. 108, n. 1, p. 1, doi. 10.1007/s00253-024-13033-5
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- Article
Isolation and characterization of a VHH targeting the Acinetobacter baumannii cell surface protein CsuA/B.
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- Applied Microbiology & Biotechnology, 2023, v. 107, n. 14, p. 4567, doi. 10.1007/s00253-023-12594-1
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Engineered Single-Domain Antibodies with High Protease Resistance and Thermal Stability.
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- PLoS ONE, 2011, v. 6, n. 11, p. 1, doi. 10.1371/journal.pone.0028218
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Evaluation of a noncanonical Cys40‐Cys55 disulfide linkage for stabilization of single‐domain antibodies.
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- Protein Science: A Publication of the Protein Society, 2019, v. 28, n. 5, p. 881, doi. 10.1002/pro.3595
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- Article