Works matching DE "GLYCOGEN synthase kinase-3"

Results: 1381

Downregulation of PHLDA2 promotes apoptosis and autophagy in endometrial cancer cells while inhibiting their proliferation and metastasis.

Published in:

European Journal of Gynaecological Oncology, 2025, v. 46, n. 5, p. 107, doi. 10.22514/ejgo.2025.071

By:

Meiping Guo;
Zhiying Wang;
Meiyan Lin

Publication type:

Article

Glycogen Synthase Kinase-3: A New Therapeutic Target in Mood Disorders.

Published in:

Klinik Psikofarmakoloji Bulteni, 2013, v. 23, n. 2, p. 193, doi. 10.5455/bcp.20130624022007

By:

Aricioglu, Feyza;
Gumru, Salih

Publication type:

Article

Discovery of a Highly Selective Glycogen Synthase Kinase-3 Inhibitor (PF-04802367) That Modulates Tau Phosphorylation in the Brain: Translation for PET Neuroimaging.

Published in:

Angewandte Chemie, 2016, v. 128, n. 33, p. 9753, doi. 10.1002/ange.201603797

By:

Liang, Steven H.;
Chen, Jinshan Michael;
Normandin, Marc D.;
Chang, Jeanne S.;
Chang, George C.;
Taylor, Christine K.;
Trapa, Patrick;
Plummer, Mark S.;
Para, Kimberly S.;
Conn, Edward L.;
Lopresti ‐ Morrow, Lori;
Lanyon, Lorraine F.;
Cook, James M.;
Richter, Karl E. G.;
Nolan, Charlie E.;
Schachter, Joel B.;
Janat, Fouad;
Che, Ye;
Shanmugasundaram, Veerabahu;
Lefker, Bruce A.

Publication type:

Article

Multitarget Drug Discovery for Alzheimer's Disease: Triazinones as BACE-1 and GSK-3β Inhibitors.

Published in:

Angewandte Chemie, 2015, v. 127, n. 5, p. 1598, doi. 10.1002/ange.201410456

By:

Prati, Federica;
De Simone, Angela;
Bisignano, Paola;
Armirotti, Andrea;
Summa, Maria;
Pizzirani, Daniela;
Scarpelli, Rita;
Perez, Daniel I.;
Andrisano, Vincenza;
Perez-Castillo, Ana;
Monti, Barbara;
Massenzio, Francesca;
Polito, Letizia;
Racchi, Marco;
Favia, Angelo D.;
Bottegoni, Giovanni;
Martinez, Ana;
Bolognesi, Maria Laura;
Cavalli, Andrea

Publication type:

Article

Top-Beiträge aus unseren Schwesterzeitschriften: Angew. Chem. 30/2013.

Published in:: Angewandte Chemie, 2013, v. 125, n. 30, p. 7782, doi. 10.1002/ange.201383013
Publication type:: Article

Cytotoxicity of alkaloids isolated from Peganum harmala seeds on HCT116 human colon cancer cells.

Published in:

Molecular Biology Reports, 2024, v. 51, n. 1, p. 1, doi. 10.1007/s11033-024-09655-7

By:

Salimizadeh, Zahra;
Enferadi, Sattar Tahmasebi;
Majidizadeh, Tayebeh;
Mahjoubi, Frouzandeh

Publication type:

Article

Beryllium is an inhibitor of cellular GSK-3β that is 1,000-fold more potent than lithium.

Published in:

BioMetals, 2014, v. 27, n. 6, p. 1203, doi. 10.1007/s10534-014-9783-y

By:

Mudireddy, Swapna;
Abdul, Ataur;
Gorjala, Priyatham;
Gary, Ronald

Publication type:

Article

Glycogen synthesis and beyond, a comprehensive review of GSK3 as a key regulator of metabolic pathways and a therapeutic target for treating metabolic diseases.

Published in:

Medicinal Research Reviews, 2022, v. 42, n. 2, p. 946, doi. 10.1002/med.21867

By:

Wang, Li;
Li, Jiajia;
Di, Li‐jun

Publication type:

Article

Cardiac fibroblast GSK-3α aggravates ischemic cardiac injury by promoting fibrosis, inflammation, and impairing angiogenesis.

Published in:

Basic Research in Cardiology, 2023, v. 118, n. 1, p. 1, doi. 10.1007/s00395-023-01005-1

By:

Umbarkar, Prachi;
Ejantkar, Suma;
Ruiz Ramirez, Sulivette Y.;
Toro Cora, Angelica;
Zhang, Qinkun;
Tousif, Sultan;
Lal, Hind

Publication type:

Article

Glycogen synthase kinase 3 beta positively regulates Notch signaling in vascular smooth muscle cells: role in cell proliferation and survival.

Published in:

Basic Research in Cardiology, 2011, v. 106, n. 5, p. 773, doi. 10.1007/s00395-011-0189-5

By:

Guha, Shaunta;
Cullen, John;
Morrow, David;
Colombo, Alberto;
Lally, Caitríona;
Walls, Dermot;
Redmond, Eileen;
Cahill, Paul

Publication type:

Article

STAT3α interacts with nuclear GSK3beta and cytoplasmic RISK pathway and stabilizes rhythm in the anoxic-reoxygenated embryonic heart.

Published in:

Basic Research in Cardiology, 2011, v. 106, n. 3, p. 355, doi. 10.1007/s00395-011-0152-5

By:

Pedretti, Sarah;
Raddatz, Eric

Publication type:

Article

Advanced glycation end products depress function of endothelial progenitor cells via p38 and ERK 1/2 mitogen-activated protein kinase pathways.

Published in:

Basic Research in Cardiology, 2009, v. 104, n. 1, p. 42, doi. 10.1007/s00395-008-0738-8

By:

Chengbo Sun;
Chun Liang;
Yusheng Ren;
Yi Zhen;
Zhiqing He;
Hua Wang;
Hongbing Tan;
Xiaoming Pan;
Zonggui Wu

Publication type:

Article

GSK3β inhibition and K<sub>ATP</sub> channel opening mediate acute opioid-induced cardioprotection at reperfusion.

Published in:

Basic Research in Cardiology, 2007, v. 102, n. 4, p. 341, doi. 10.1007/s00395-007-0651-6

By:

Gross, Eric R.;
Hsu, Anna K.;
Gross, Garrett J.

Publication type:

Article

The effects of oral taurine administration on behavior and hippocampal signal transduction in rats.

Published in:

Amino Acids, 2012, v. 43, n. 5, p. 2037, doi. 10.1007/s00726-012-1282-2

By:

Iio, Wataru;
Matsukawa, Noriko;
Tsukahara, Takamitsu;
Toyoda, Atsushi

Publication type:

Article

Effect of double mutations K214/A-E215/Q of FRATide on GSK3β: insights from molecular dynamics simulation and normal mode analysis.

Published in:

Amino Acids, 2012, v. 43, n. 1, p. 267, doi. 10.1007/s00726-011-1070-4

By:

Lu, Shao-Yong;
Jiang, Yong-Jun;
Zou, Jian-Wei;
Wu, Tian-Xing

Publication type:

Article

FDA Approves GSK Vaccine Arexvy for Prevention of RSV in High-Risk Adults Aged 50 to 59 Years.

Published in:

Patient Care (Online), 2024, p. 1

By:

Halsey, Grace

Publication type:

Article

T cell memory: Live long with WNT.

Published in:

Nature Reviews Immunology, 2009, v. 9, n. 7, p. 460, doi. 10.1038/nri2594

By:

Bird, Lucy

Publication type:

Article

Cadmium inhibits neural stem/progenitor cells proliferation via MitoROS‐dependent AKT/GSK‐3β/β‐catenin signaling pathway.

Published in:

Journal of Applied Toxicology, 2021, v. 41, n. 12, p. 1998, doi. 10.1002/jat.4179

By:

Luo, Huan;
Song, Bo;
Xiong, Guiya;
Zhang, Bing;
Zuo, Zhenzi;
Zhou, Zhijun;
Chang, Xiuli

Publication type:

Article

Deletion or inhibition of prolyl oligopeptidase blocks lithium‐induced phosphorylation of GSK3b and Akt by activation of protein phosphatase 2A.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2021, v. 129, n. 4, p. 287, doi. 10.1111/bcpt.13632

By:

Myöhänen, Timo T.;
Mertens, Freke;
Norrbacka, Susanna;
Cui, Hengjing

Publication type:

Article

Antinociceptive and Anti-Inflammatory Effects of Ketamine and the Relationship to Its Antidepressant Action and GSK3 Inhibition.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2016, v. 119, n. 6, p. 562, doi. 10.1111/bcpt.12637

By:

Vale, Eduardo Mulato;
Xavier, Cecília Coelho;
Nogueira, Brenda Gomes;
Campos, Bruna Caldas;
Aquino, Pedro Everson Alexandre;
Costa, Roberta Oliveira;
Leal, Luzia Kalyne Almeida Moreira;
Vasconcelos, Silvânia Maria Mendes;
Neves, Kelly Rose Tavares;
Barros Viana, Glauce Socorro

Publication type:

Article

Resveratrol Inhibits Venezuelan Equine Encephalitis Virus Infection by Interfering with the AKT/GSK Pathway.

Published in:

Plants (2223-7747), 2021, v. 10, n. 2, p. 346, doi. 10.3390/plants10020346

By:

Lehman, Caitlin W.;
Kehn-Hall, Kylene;
Aggarwal, Megha;
Bracci, Nicole R.;
Pan, Han-Chi;
Panny, Lauren;
Lamb, Robert A.;
Lin, Shih-Chao;
Pintus, Francesca

Publication type:

Article

Strigolactone Signaling Genes Showing Differential Expression Patterns in Arabidopsis max Mutants.

Published in:

Plants (2223-7747), 2019, v. 8, n. 9, p. 352, doi. 10.3390/plants8090352

By:

Kumar, Manu;
Kim, Inyoung;
Kim, Yeon-Ki;
Heo, Jae Bok;
Suh, Mi Chung;
Kim, Hyun Uk

Publication type:

Article

Decrease of glycogen synthase kinase 3β phosphorylation in the rat nucleus accumbens shell is necessary for amphetamine-induced conditioned locomotor activity.

Published in:

Korean Journal of Physiology & Pharmacology, 2022, v. 26, n. 1, p. 59, doi. 10.4196/kjpp.2022.26.1.59

By:

Joong-Keun Shin;
Wha Young Kim;
Haeun Rim;
Jeong-Hoon Kim

Publication type:

Article

Puerarin pretreatment attenuates cardiomyocyte apoptosis induced by coronary microembolization in rats by activating the PI3K/Akt/GSK-3β signaling pathway.

Published in:

Korean Journal of Physiology & Pharmacology, 2021, v. 25, n. 2, p. 147, doi. 10.4196/kjpp.2021.25.2.147

By:

Zhi-Qing Chen;
You Zhou;
Jun-Wen Huang;
Feng Chen;
Jing Zheng;
Hao-Liang Li;
Tao Li;
Lang Li

Publication type:

Article

Exploring the beneficial role of telmisartan in sepsis-induced myocardial injury through inhibition of high-mobility group box 1 and glycogen synthase kinase-3β/nuclear factor-κB pathway.

Published in:

Korean Journal of Physiology & Pharmacology, 2020, v. 24, n. 4, p. 311, doi. 10.4196/kjpp.2020.24.4.311

By:

Yan Jin;
Hong Wang;
Jing Li;
Minyan Dang;
Wenzhi Zhang;
Yan Lei;
Hao Zhao

Publication type:

Article

Effect of GSK-3 activity, enzymatic inhibition and gene silencing by RNAi on tick oviposition and egg hatching.

Published in:: Parasitology, 2010, v. 137, n. 10, p. 1537, doi. 10.1017/S0031182010000284
Publication type:: Article

Dihydroartemisinin triggers c-Myc proteolysis and inhibits protein kinase B/glycogen synthase kinase 3β pathway in T-cell lymphoma cells.

Published in:

Oncology Letters, 2018, v. 16, n. 5, p. 6838, doi. 10.3892/ol.2018.9450

By:

Wei, Wenwen;
Zhao, Xindong;
Wu, Shaoling;
Zhao, Chunting;
Zhao, Hongguo;
Sun, Lingjie;
Cui, Yujiao

Publication type:

Article

Expression profile and clinical significance of Wnt signaling in human gliomas.

Published in:

Oncology Letters, 2018, v. 15, n. 1, p. 610, doi. 10.3892/ol.2017.7315

By:

Zhang, Hao;
Qi, Yanhua;
Geng, Decheng;
Shi, Yi;
Wang, Xu;
Yu, Rutong;
Zhou, Xiuping

Publication type:

Article

Glycogen synthase kinase-3β regulates tumor necrosis factor-related apoptosis inducing ligand (TRAIL)-induced apoptosis via the NF-κB pathway in hepatocellular carcinoma.

Published in:

Oncology Letters, 2015, v. 10, n. 6, p. 3557, doi. 10.3892/ol.2015.3803

By:

KAI FU;
HUAZHENG PAN;
SHIHAI LIU;
JING LV;
ZHAOJUN WAN;
JIAO LI;
QING SUN;
JUN LIANG

Publication type:

Article

Investigating the Protective Effect of Gross Saponins of Tribulus terrestris Fruit against Ischemic Stroke in Rat Using Metabolomics and Network Pharmacology.

Published in:

Metabolites (2218-1989), 2019, v. 9, n. 10, p. 240, doi. 10.3390/metabo9100240

By:

Wang, Yang;
Guo, Wenjun;
Liu, Yue;
Wang, Jifeng;
Fan, Meiling;
Zhao, Hongyu;
Xie, Shengxu;
Xu, Yajuan

Publication type:

Article

Glycogen synthase kinases in model and crop plants -- From negative regulators of brassinosteroid signaling to multifaceted hubs of various signaling pathways and modulators of plant reproduction and yield.

Published in:

Frontiers in Plant Science, 2022, v. 13, p. 01, doi. 10.3389/fpls.2022.939487

By:

Zolkiewicz, Karolina;
Gruszka, Damian

Publication type:

Article

Galangin Attenuates Isoproterenol-Induced Inflammation and Fibrosis in the Cardiac Tissue of Albino Wistar Rats.

Published in:

Frontiers in Pharmacology, 2020, v. 11, p. N.PAG, doi. 10.3389/fphar.2020.585163

By:

Thangaiyan, Radhiga;
Arjunan, Sundaresan;
Govindasamy, Kanimozhi;
Khan, Haseeb A.;
Alhomida, Abdullah S.;
Prasad, Nagarajan Rajendra

Publication type:

Article

Hyperoside Protected Against Oxidative Stress-Induced Liver Injury via the PHLPP2-AKT-GSK-3β Signaling Pathway In Vivo and In Vitro.

Published in:

Frontiers in Pharmacology, 2020, v. 11, p. 1, doi. 10.3389/fphar.2020.01065

By:

Xing, Haiyan;
Fu, Ruoqiu;
Cheng, Caiyi;
Cai, Yongqing;
Wang, Xianfeng;
Deng, Dongmei;
Gong, Xiaoyuan;
Chen, Jianhong

Publication type:

Article

Inhibition of GSK3β and RIP1K Attenuates Glial Scar Formation Induced by Ischemic Stroke via Reduction of Inflammatory Cytokine Production.

Published in:

Frontiers in Pharmacology, 2020, v. 11, p. 1, doi. 10.3389/fphar.2020.00812

By:

Liu, Jin;
Zhu, Yong-Ming;
Guo, Yi;
Lin, Liang;
Wang, Zhan-Xiang;
Gu, Feng;
Dong, Xin-Yi;
Zhou, Ming;
Wang, Yi-Fan;
Zhang, Hui-Ling

Publication type:

Article

Editorial: Autophagy and Related Transcription Factors in Liver and Gut Diseases.

Published in:

2020

By:

Eid, Nabil;
Menon, Manoj B.;
Thomes, Paul;
Zeng, Tao;
Raimundo, Nuno;
Fernandez-Checa, Jose C.;
Wang, Lin;
Ito, Yuko;
Otsuki, Yoshinori;
Adeghate, Ernest

Publication type:

Editorial

Multi-omics analyses reveal the specific changes in gut metagenome and serum metabolome of patients with polycystic ovary syndrome.

Published in:

Frontiers in Microbiology, 2022, v. 13, p. 1, doi. 10.3389/fmicb.2022.1017147

By:

Zhandong Yang;
Huijiao Fu;
Huihui Su;
Xuzi Cai;
Yan Wang;
Yanjun Hong;
Jing Hu;
Zhiyong Xie;
Xuefeng Wang

Publication type:

Article

FcαRI Dynamics Are Regulated by GSK-3 and PKCζ During Cytokine Mediated Inside-Out Signaling.

Published in:

Frontiers in Immunology, 2019, p. N.PAG, doi. 10.3389/fimmu.2018.03191

By:

ten Broeke, Toine;
Honing, Henk;
Brandsma, Arianne M.;
Jacobino, Shamir;
Bakema, Jantine E.;
Kanters, Deon;
van der Linden, Jan A. M.;
Bracke, Madelon;
Koenderman, Leo;
Leusen, Jeanette H. W.

Publication type:

Article

Decoding the multifaceted interventions between human sirtuin 2 and dynamic hepatitis B viral proteins to confirm their roles in HBV replication.

Published in:

Frontiers in Cellular & Infection Microbiology, 2024, p. 1, doi. 10.3389/fcimb.2023.1234903

By:

Piracha, Zahra Zahid;
Saeed, Umar;
Piracha, Irfan Ellahi;
Noor, Seneen;
Noor, Elyeen

Publication type:

Article

Dietary daidzein improves the development of intestine subjected to soybean meal in juvenile turbot (Scophthalmus maximus L.).

Published in:

Aquaculture Nutrition, 2021, v. 27, n. 1, p. 17, doi. 10.1111/anu.13161

By:

Yu, Guijuan;
Liu, Yang;
Dai, Jihong;
Ou, Weihao;
Ai, Qinghui;
Zhang, Wenbing;
Mai, Kangsen;
Zhang, Yanjiao

Publication type:

Article

Glycogen synthase kinase 3β inhibition sensitizes pancreatic cancer cells to gemcitabine.

Published in:

Journal of Gastroenterology, 2012, v. 47, n. 3, p. 321, doi. 10.1007/s00535-011-0484-9

By:

Shimasaki, Takeo;
Ishigaki, Yasuhito;
Nakamura, Yuka;
Takata, Takanobu;
Nakaya, Naoki;
Nakajima, Hideo;
Sato, Itaru;
Zhao, Xia;
Kitano, Ayako;
Kawakami, Kazuyuki;
Tanaka, Takuji;
Takegami, Tsutomu;
Tomosugi, Naohisa;
Minamoto, Toshinari;
Motoo, Yoshiharu

Publication type:

Article

Inhibiting Effect of Lithium Chloride on Endotoxin-induced Uveitis in Rats.

Published in:

2018

By:

Yang, Shuo;
Yu, Shuo;
Liu, Xinli;
Zhang, Xiaosheng;
Lu, Hong;
Yu, Jinyi

Publication type:

journal article

How lithium treatment generates neutrophilia by enhancing phosphorylation of GSK-3, increasing HIF-1 levels and how this path is important during engraftment.

Published in:

Bone Marrow Transplantation, 2008, v. 41, n. 1, p. 23, doi. 10.1038/sj.bmt.1705872

By:

Kast, R. E.

Publication type:

Article

Combined regulation of mTORC1 and lysosomal acidification by GSK-3 suppresses autophagy and contributes to cancer cell growth.

Published in:

Oncogene, 2015, v. 34, n. 35, p. 4613, doi. 10.1038/onc.2014.390

By:

Azoulay-Alfaguter, I;
Elya, R;
Avrahami, L;
Katz, A;
Eldar-Finkelman, H

Publication type:

Article

Effect of glycogen synthase kinase-3 inactivation on mouse mammary gland development and oncogenesis.

Published in:

Oncogene, 2015, v. 34, n. 27, p. 3514, doi. 10.1038/onc.2014.279

By:

Dembowy, J;
Adissu, H A;
Liu, J C;
Zacksenhaus, E;
Woodgett, J R

Publication type:

Article

Analysis of the mechanism of skeletal muscle atrophy from the pathway of decreased protein synthesis.

Published in:

Frontiers in Physiology, 2025, p. 1, doi. 10.3389/fphys.2025.1533394

By:

Chen, Peng;
Jia, Fangfang;
Wang, Meng;
Yang, Shengbo

Publication type:

Article

Partial Least Squares Discriminant Analysis and 3D Similarity Perspective Applied to Analyze Comprehensively the Selectivity of Glycogen Synthase Kinase 3 Inhibitors.

Published in:

Molecular Informatics, 2020, v. 39, n. 6, p. 1, doi. 10.1002/minf.201900142

By:

Crisan, Luminita;
Avram, Sorin;
Kurunczi, Ludovic;
Pacureanu, Liliana

Publication type:

Article

Editorial.

Published in:

Guident, 2013, v. 6, n. 6, p. 6

By:

Khan, Parvez A.

Publication type:

Article

Cell surface integrin α5ß1 clustering negatively regulates receptor tyrosine kinase signaling in colorectal cancer cells via glycogen synthase kinase 3.

Published in:

Integrative Biology, 2021, v. 13, n. 6, p. 153, doi. 10.1093/intbio/zyab009

By:

Starchenko, Alina;
Graves-Deal, Ramona;
Brubaker, Douglas;
Li, Cunxi;
Yang, Yuping;
Singh, Bhuminder;
Coffey, Robert J;
Lauffenburger, Douglas A

Publication type:

Article

Identification of a WNT5A-Responsive Degradation Domain in the Kinesin Superfamily Protein KIF26B.

Published in:

Genes, 2018, v. 9, n. 4, p. 196, doi. 10.3390/genes9040196

By:

Karuna, Edith P.;
Choi, Shannon S.;
Scales, Michael K.;
Hum, Jennie;
Cohen, Michael;
Fierro, Fernando A.;
Ho, Hsin-Yi Henry

Publication type:

Article

Drug repurposing for tooth regeneration: The promising premises.

Published in:

Journal of Pharmacy & Bioallied Sciences, 2021, v. 13, p. 957, doi. 10.4103/jpbs.jpbs_67_21

By:

Divya, T;
Muddappa, Sapna;
Singh, Prabath;
Rajan, Rakesh;
Remya, M;
Sreehari, Deepthy

Publication type:

Article