Works matching DE "CELLULAR signal transduction"

Results: 5000

CLIC1 Supports Mechanisms Related to Platelet Activation and Thrombosis.

Published in:

Transfusion Medicine & Hemotherapy, 2025, v. 52, n. 3, p. 178, doi. 10.1159/000544115

By:

Knowles, Lynn M.;
Ampofo, Emmanuel;
Menger, Michael D.;
Drawz, Anna;
Eichler, Hermann;
Pilch, Jan

Publication type:

Article

Mechanisms of organotropism in breast cancer and predicting metastasis to distant organs using deep learning.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02905-5

By:

Xiao, Meizhu;
Fu, Zhijin;
Li, Yanjiao;
Zhang, Min;
Zhang, Denan;
Liu, Lei;
Jin, Qing;
Chen, Xiujie;
Xie, Hongbo

Publication type:

Article

Tissue degrading and remodelling molecules in giant cell arteritis Open Access.

Published in:

Rheumatology, 2025, v. 64, n. 5, p. 3095, doi. 10.1093/rheumatology/keae710

By:

Watanabe, Nobumasa;
Hara, Yuichiro;
Nishito, Yasumasa;
Kounoe, Mai;
Sekiyama, Kazunari;
Takamasu, Eisuke;
Kise, Takayasu;
Chinen, Naofumi;
Shimada, Kota;
Sugihara, Makoto;
Kawaji, Hideya

Publication type:

Article

The role and mechanism of CRISPLD2 in skin fibrosis of systemic sclerosis.

Published in:

Rheumatology, 2025, v. 64, n. 5, p. 3134, doi. 10.1093/rheumatology/keae541

By:

Ding, Liqing;
Bao, Ding;
Dai, Bingying;
Meng, Qiming;
Lv, Chunliu;
Luo, Hui;
Zhu, Honglin

Publication type:

Article

Association of gut commensal translocation with autoantibody production in systemic lupus erythematosus.

Published in:

Rheumatology, 2025, v. 64, n. 5, p. 3104, doi. 10.1093/rheumatology/keae476

By:

Katsushima, Masao;
Nakayama, Yoichi;
Yoshida, Tsuneyasu;
Nishida, Yuri;
Shirakashi, Mirei;
Nakashima, Ran;
Yoshifuji, Hajime;
Ito, Shinji;
Satoh, Junko;
Yamamoto, Masaki;
Watanabe, Ryu;
Emori, Takashi;
Kamiya, Tomonori;
Nitahara, Yuko;
Nakagama, Yu;
Ohtani, Naoko;
Kido, Yasutoshi;
Morinobu, Akio;
Hashimoto, Motomu

Publication type:

Article

Multiple intramolecular triggers converge to preferential G protein coupling in the CB2R.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-60003-0

By:

Morales-Pastor, Adrian;
Miljuš, Tamara;
Dieguez-Eceolaza, Miguel;
Stępniewski, Tomasz Maciej;
Ledesma-Martin, Vicente;
Heydenreich, Franziska M.;
Flock, Tilman;
Plouffe, Bianca;
Le Gouill, Christian;
Duchaine, Jean;
Sykes, David A.;
Nicholson, Colin;
Koers, Eline J.;
Guba, Wolfgang;
Rufer, Arne C.;
Grether, Uwe;
Bouvier, Michel;
Veprintsev, Dmitry B.;
Selent, Jana

Publication type:

Article

槲皮素防治肝细胞癌相关信号通路研究进展.

Published in:

Evaluation & Analysis of Drug-Use in Hospitals of China / Zhongguo Yiyuan Yongyao Pingjia yu Fenxi, 2025, v. 25, n. 5, p. 632, doi. 10.14009/j.issn.1672-2124.2025.05.025

By:

姚三飞;
刘江凯

Publication type:

Article

Phytochemical Characterization, Antioxidant Activity, and Anti-Melanoma Mechanism of Flower Buds of Magnolia biondii Pamp.

Published in:

Plants (2223-7747), 2025, v. 14, n. 11, p. 1725, doi. 10.3390/plants14111725

By:

Li, Shanshan;
Jiao, Gege;
Ou, Penghui;
Zhang, Xiaona;
Yu, Yang;
Wang, Yihui;
Yao, Qingping;
Wang, Wei

Publication type:

Article

IAA-Mediated Haustorium Formation in Phelipanche aegyptiaca : Transcriptional Insights and Anti-Parasitic Strategies.

Published in:

Plants (2223-7747), 2025, v. 14, n. 11, p. 1591, doi. 10.3390/plants14111591

By:

Hu, Xin;
Cao, Xiaolei;
Zhao, Qiuyue;
Zeng, Xiaojian;
Wei, Yingming;
Yao, Zhaoqun;
Zhao, Sifeng

Publication type:

Article

The Peptide-Encoding CLE25 Gene Modulates Drought Response in Cotton.

Published in:

Agriculture; Basel, 2025, v. 15, n. 11, p. 1226, doi. 10.3390/agriculture15111226

By:

Zhang, Dayong;
Zhu, Qingfeng;
Qin, Pu;
Yu, Lu;
Li, Weixi;
Sun, Hao

Publication type:

Article

Wenqing Yin Attenuates the Allergic Contact Dermatitis Response by Inhibiting the JAK2/STAT1 and MAPK Signaling Pathways.

Published in:

Journal of Inflammation Research, 2025, v. 18, p. 7013, doi. 10.2147/JIR.S512868

By:

Ren, Mengyue;
Li, Siman;
Li, Shaoqiang;
Tan, Zhiwei;
Shi, Jun

Publication type:

Article

RhIL-11 reverses liver damage in septic mice by STAT3-mediated M-MDSCs induction modulated by a parallel mTORC1 signaling branch.

Published in:

Journal of Inflammation, 2025, v. 22, n. 1, p. 1, doi. 10.1186/s12950-025-00447-9

By:

Liu, Yuefang;
Gao, Shujun;
Li, Zhanghui;
Yin, Lei;
Ge, Shiyao;
Zhao, Yangjing;
Wang, Hui;
Wan, Bing;
Shao, Qixiang

Publication type:

Article

HSP110 Regulates the Assembly of the SWI/SNF Complex.

Published in:

Cells (2073-4409), 2025, v. 14, n. 11, p. 849, doi. 10.3390/cells14110849

By:

Pointeau, Océane;
Paccagnini, Manon;
Borges-Bonan, Natalia;
Biziorek, Léo;
Causse, Sébastien;
Garrido, Carmen;
Dubrez, Laurence

Publication type:

Article

Hypoxia Promotes the In Vitro Proliferation of Buffalo Spermatogonial Cells by Increasing Lactate and H3K18la Lactylation Levels.

Published in:

Cells (2073-4409), 2025, v. 14, n. 11, p. 832, doi. 10.3390/cells14110832

By:

Li, Mengqi;
Ma, Yanyu;
Wang, Shenzhi;
Zheng, Haiying;
Yang, Chunyan;
Duan, Anqin;
Zhou, Benliang;
Shang, Jianghua;
Liang, Xingwei;
Yang, Xiaogan

Publication type:

Article

The cGAS/STING Pathway: Friend or Foe in Regulating Cardiomyopathy.

Published in:

Cells (2073-4409), 2025, v. 14, n. 11, p. 778, doi. 10.3390/cells14110778

By:

Wang, Weiyue;
Gao, Yuanxu;
Lee, Hyun Kyoung;
Yu, Albert Cheung-Hoi;
Kipp, Markus;
Kaddatz, Hannes;
Zhan, Jiangshan

Publication type:

Article

PDE3A as a Therapeutic Target for the Modulation of Compartmentalised Cyclic Nucleotide-Dependent Signalling.

Published in:

Cells (2073-4409), 2025, v. 14, n. 11, p. 771, doi. 10.3390/cells14110771

By:

Pati, Swaroop Ranjan;
Sholokh, Anastasiia;
Klussmann, Enno

Publication type:

Article

Progranulin's Protective Mechanisms and Therapeutic Potential in Cardiovascular Disease.

Published in:

Cells (2073-4409), 2025, v. 14, n. 11, p. 762, doi. 10.3390/cells14110762

By:

Qiao, Gan;
Lu, Yongxiang;
Wu, Jianping;
Ren, Chunyang;
Lin, Roudian;
Zhang, Chunxiang

Publication type:

Article

The Electronic Properties of Cordycepin in the Adenine Nucleoside Landscape: A Theoretical Approach.

Published in:

Molecules, 2025, v. 30, n. 11, p. 2289, doi. 10.3390/molecules30112289

By:

Karwowski, Boleslaw T.

Publication type:

Article

The Role of Scleral Changes in the Progression of Myopia: A Review and Future Directions.

Published in:

Clinical Ophthalmology, 2025, v. 19, p. 1699, doi. 10.2147/OPTH.S523283

By:

Yin, Xiaofan;
Ge, Jinling

Publication type:

Article

Decoding extracellular matrix–lysosome cross-talk and its implications for neurodegenerative diseases.

Published in:

Science Signaling, 2025, v. 18, n. 890, p. 1, doi. 10.1126/scisignal.adt1936

By:

Yang, Qinghu;
Ma, Huan;
Yang, Liang;
Jiang, Ming;
Liu, Xia;
Bai, Zhantao

Publication type:

Article

Case Series of Patients With FGFR1‐Related Pheochromocytoma and Paraganglioma With a Focus on Biochemical, Imaging Signatures and Treatment Options.

Published in:

Clinical Endocrinology, 2025, v. 102, n. 6, p. 626, doi. 10.1111/cen.15212

By:

Jhawar, Sakshi;
Jha, Abhishek;
Talvacchio, Sara;
Kamihara, Junne;
Del Rivero, Jaydira;
Pacak, Karel

Publication type:

Article

Immunotherapy Applications in Urology.

Published in:

Journal of Urological Surgery, 2025, v. 12, n. 2, p. 1, doi. 10.4274/jus.galenos.2025.2024-11-9

By:

Şenoğlu, Yusuf;
Şahin, Bahadır

Publication type:

Article

Wnt/β-catenin mediated signaling pathways in cancer: recent advances, and applications in cancer therapy.

Published in:

Molecular Cancer, 2025, v. 24, n. 1, p. 1, doi. 10.1186/s12943-025-02363-1

By:

Wu, Xiuzhu;
Que, Haiying;
Li, Qingfang;
Wei, Xiawei

Publication type:

Article

Revisiting galectin-1, -3, -4, and -9 as biotargets for colorectal cancer.

Published in:

Biochemistry & Cell Biology, 2025, v. 103, p. 1, doi. 10.1139/bcb-2024-0218

By:

Kamarudin, Ammar Akram;
Abu, Nadiah

Publication type:

Article

[Retracted] Upregulation of miR-34a by diallyl disulfide suppresses invasion and induces apoptosis in SGC-7901 cells through inhibition of the PI3K/Akt signaling pathway.

Published in:

2025

By:

Wang, Guojun;
Liu, Guanghui;
Ye, Yanwei;
Fu, Yang;
Zhang, Xiefu

Publication type:

Correction Notice

[Retracted] Metformin mitigates PLC? gene expression and modulates the Notch1/Hes and androgen receptor signaling pathways in castration?resistant prostate cancer xenograft models.

Published in:

2025

By:

Li, Qi;
Xu, Ke;
Tian, Jianguo;
Lu, Zhicheng;
Pu, Jianming

Publication type:

Correction Notice

Advances in the molecular signaling mechanisms of VEGF/VEGFR2 in fundus neovascularization disease (Review).

Published in:

Experimental & Therapeutic Medicine, 2025, v. 30, n. 1, p. N.PAG, doi. 10.3892/etm.2025.12893

By:

Li, Huan Shen;
Huang, Xiong Gao

Publication type:

Article

LRG1 in cancer: mechanisms, potential therapeutic target, and use in clinical diagnosis.

Published in:

Molecular Biology Reports, 2025, v. 52, n. 1, p. 1, doi. 10.1007/s11033-025-10669-y

By:

Osorio-Antonio, Federico;
Diaz-González, Daniela Michel;
Bautista-Rodríguez, Elizabeth;
Campos-Viguri, Gabriela Elizabeth;
Peralta-Zaragoza, Oscar;
Sánchez-López, José Manuel;
Cortez-Sánchez, José Luis;
Muñoz-Olivos, Cristina;
Castelán, Francisco;
Velázquez-Orozco, Verónica

Publication type:

Article

Dose-dependent immunotoxic mechanisms of celastrol via modulation of the PI3K-Akt signaling pathway.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1567193

By:

Geng, Shaohui;
Wen, Jingqi;
Shen, Chunli;
Liu, Li;
Jiang, Yijin;
Fu, Jingyuan;
Guan, Yiwei;
Ye, Zi;
Wu, Yuanhao;
Li, Chen;
Huang, Guangrui

Publication type:

Article

The role of CXCL16 in atherosclerosis: from mechanisms to therapy.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1555438

By:

Liu, Yue;
Tian, Xintao;
Jia, Chunyan;
Cheng, Xinrui;
Cui, Changxing;
Li, Cuiping;
Yang, Shaonan

Publication type:

Article

Electroacupuncture ameliorates cartilage damage in a rat model of knee osteoarthritis and regulates expression of miRNAs and the TLR4/NF-κB pathway.

Published in:

Acupuncture in Medicine, 2025, v. 43, n. 3, p. 164, doi. 10.1177/09645284251342259

By:

Wang, Zhenzhen;
Zheng, Xiahai;
Lin, Jing;
Zhou, Bin;
Zeng, Zhenming;
Gao, Haiwei;
Chen, Haoxiong;
Tang, Chunzhi

Publication type:

Article

Electroacupuncture attenuates bone erosion and promotes macrophage polarization in a mouse model of collagen-induced arthritis.

Published in:

Acupuncture in Medicine, 2025, v. 43, n. 3, p. 150, doi. 10.1177/09645284251331991

By:

Dong, Shi-Ying;
Zhou, Ying;
Wang, Xiao-Chi;
Du, Zhong-Heng;
Ye, Tian-Shen

Publication type:

Article

Unveiling the immunopharmacological mechanisms of Danggui Yinzi (DGYZ) in treating chronic urticaria: insights from network pharmacology and experimental validation.

Published in:

Chinese Medicine, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13020-025-01137-7

By:

Wang, Xu-rui;
Chen, An-jing;
Hou, Chang-cheng;
Wang, Yue-yue;
Guo, Jing;
Li, Ming-yue

Publication type:

Article

Discovery of components in honeysuckle for treating COVID-19 and diabetes based on molecular docking, network analysis and experimental validation.

Published in:

Natural Product Research, 2025, v. 39, n. 12, p. 3459, doi. 10.1080/14786419.2024.2340040

By:

Xu, Feng;
Qin, Ya;
Guan, Changxiu

Publication type:

Article

Unlocking the Secrets of Insects: The Role of Mass Spectrometry to Understand the Life of Insects.

Published in:

Mass Spectrometry Reviews, 2025, v. 44, n. 4, p. 543, doi. 10.1002/mas.21922

By:

Mayorga‐Martino, Vanessa;
Mansurova, Madina;
Calla‐Quispe, Erika;
Ibáñez, Alfredo J.

Publication type:

Article

بررسی اثر دگزامتازون بر سایتوکاینها و بیان ژنها منتخب دخیل در فیبروز مطالعه در مدل موشی فیبروز ریوی ایدیوپاتیک.

Published in:

Razi Journal of Medical Sciences, 2023, v. 30, n. 6, p. 195

By:

صابر مهدی زاده;
مرجان طاهریان;
کاظم موسوی زاده;
سالار پشنگ زاده;
پریا بیاتی;
علی انیسیان;
نازنین مجتبوی

Publication type:

Article

Neuroprotection unveiled: melatonin mitigates apoptotic pathways in traumatic brain injury.

Published in:

Frontiers in Neurology, 2025, p. 1, doi. 10.3389/fneur.2025.1551449

By:

Gunara, Sezer Onur;
Akgun, Mehmet Yigit;
Seker, Ugur;
Ucar, Ege Anil;
Ates, Ozkan;
Basar, Ibrahim

Publication type:

Article

LRP1 Mediates Endocytosis Activity and Is a Potential Therapeutic Target in Osteoarthritis.

Published in:

Orthopaedic Surgery, 2025, v. 17, n. 6, p. 1604, doi. 10.1111/os.70035

By:

Wu, Yuangang;
Sun, Kaibo;
Li, Mingyang;
Yang, Yang;
Liu, Yuan;
Wu, Limin;
Ding, Yang;
Zeng, Yi;
Shen, Bin

Publication type:

Article

miR-19a-3p enhances TGF-β1-induced cardiac fibroblast activation via targeting BAMBI.

Published in:

Journal of Biomedical Research, 2025, v. 39, n. 2, p. 171, doi. 10.7555/JBR.37.20230313

By:

Pengxi Shi;
Ao Tan;
Yuanyuan Ma;
Lingli Que;
Chuanfu Li;
Yongfeng Shao;
Haoliang Sun;
Yuehua Li;
Jiantao Li

Publication type:

Article

Unveiling the role of lipid metabolism in haemorrhagic disorders: genetic insights and therapeutic perspectives.

Published in:

Thrombosis Journal, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12959-025-00731-x

By:

Wei, Jiaqi;
Yang, Zhen;
Wu, Xiaojin;
Zheng, Nana;
Wu, Depei

Publication type:

Article

Correlation between dyslipidaemia and gastric cancer: pathogenesis to prevention and treatment strategies.

Published in:

Lipids in Health & Disease, 2025, v. 24, n. 1, p. 1, doi. 10.1186/s12944-025-02625-3

By:

Wu, Tao;
Zhang, Lingna;
Tian, Jiao;
Lu, Yuyuan;
Yang, Yan;
Yang, Xin;
Jin, Penghui;
Gu, Yuanhui;
Wang, Xiaoke;
Yi, Lin

Publication type:

Article

Study on characteristics of gut flora composition of pregnant women with preeclampsia.

Published in:

BMC Pregnancy & Childbirth, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12884-025-07760-4

By:

Li, Genxia;
Niu, Huan;
Xie, Mingkun;
Yang, Manman;
Li, Mengyu;
Hao, Yujing;
Zhang, Junya

Publication type:

Article

Role of agonistic autoantibodies to the angiotensin II type 1 receptor (AT1-AA) in pathogenesis of preeclampsia.

Published in:

Global Medical Genetics, 2025, v. 12, n. 2, p. 1, doi. 10.1016/j.gmg.2025.100041

By:

Jing Wang;
Lijuan Shan;
Yanhui Zhao;
Hongwen Cao;
Shuhai Lan;
Yizi Yan

Publication type:

Article

The pathogenesis of B-cell non-hodgkin lymphoma associated with HBV (hepatitis B virus) infection is regulated by c-Myc/PD-L1 signaling pathway.

Published in:

Global Medical Genetics, 2025, v. 12, n. 1, p. 1, doi. 10.1016/j.gmg.2024.100001

By:

Yu Zhao;
Jian Yang;
Sai Xu;
Ying Wang;
Jian Bo

Publication type:

Article

Inhibition of p38-MK2 pathway enhances the efficacy of microtubule inhibitors in breast cancer cells.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.104859

By:

Yu-Chia Chen;
Mamoru Takada;
Aerica Nagornyuk;
Muhan Yu;
Hideyuki Yamada;
Takeshi Nagashima;
Masayuki Ohtsuka;
DeLuca, Jennifer G.;
Markus, Steven M.;
Motoki Takaku;
Aussie Suzuki

Publication type:

Article

MCM3 promotes hepatocellular carcinoma progression via Epithelial-mesenchymal Transition through AKT/Twist signaling pathway.

Published in:

Annals of Hepatology: Official Journal of the Mexican Association of Hepatology, 2025, v. 30, n. 1, p. 1, doi. 10.1016/j.aohep.2025.101785

By:

Wei-Guo Tang;
Jin-Feng Feng;
Xian Li;
Qi-Man Sun;
Jin-Wu Hu;
Xiao-Lu Ma;
Yan-Yan Nie;
Yang Xu;
Jian Sun;
Qi-Meng Chang

Publication type:

Article

CMTM7 inhibits TLR4 signaling pathway via promoting Rab5 activation and alleviates acute liver injury.

Published in:

Cellular & Molecular Life Sciences, 2025, v. 82, n. 1, p. 1, doi. 10.1007/s00018-025-05748-z

By:

Sun, Yingzhe;
Guo, Zixia;
Huo, Yangbo;
Zhang, Hanxiao;
Li, Ting;
Wang, Pingzhang;
Han, Wenling

Publication type:

Article

Elucidating Ras protein as a dual therapeutic target for inflammation and cancer: a review.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02783-x

By:

Nandan, Parmar Keshri;
Sivaraman, Jayanthi

Publication type:

Article

Anti-oxidative effect of Salvia miltiorrhiza Bunge fermented with Shiraia bambusicola Henn. against H2O2-induced injury in PC12 cells.

Published in:

BMC Complementary Medicine & Therapies, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12906-025-04956-1

By:

Wang, Qiaona;
Zhu, Canhe;
Song, Zhaoran;
Qiao, Yunfa;
Hu, Yuefeng;
Hu, Liyun;
Li, Shengjie;
Wang, Renlei

Publication type:

Article

Mitigation of radiation mediated testicular dysfunction by α-tocopheryl succinate: PPAR-γ related pathway.

Published in:

BMC Complementary Medicine & Therapies, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12906-025-04950-7

By:

Gheita, Heba A.;
Shafey, Ghada M.;
Aziz, Maha M.;
Fadel, Noha A.

Publication type:

Article