Works matching DE "POLY ADP ribose"

Results: 947

The Interplay Between DNA Repair and the Immune Microenvironment in Pancreatic Cancer.

Published in:

Biomedicines, 2025, v. 13, n. 5, p. 1031, doi. 10.3390/biomedicines13051031

By:

Ciner, Aaron;
Hosein, Peter J.;
Jiang, Yixing;
Rassool, Feyruz

Publication type:

Article

PARP1 and CBP lose their footing in cancer.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 11, p. 947, doi. 10.1038/nsmb.2913

By:

Timinszky, Gyula;
Ladurner, Andreas G

Publication type:

Article

Identification of the novel BRCA1 c.2463_2464delTA mutation in two high grade serous ovarian cancer sisters and potential dosage effects implications: a case report.

Published in:

Molecular Biology Reports, 2025, v. 52, n. 1, p. 1, doi. 10.1007/s11033-024-10213-4

By:

Lombardo, Valentina;
Scandurra, Giuseppa;
Pettinato, Angela;
Scaglione, Giovanni Luca;
Scollo, Paolo;
Capoluongo, Ettore D.

Publication type:

Article

Identification of the novel BRCA1 c.2463_2464delTA mutation in two high grade serous ovarian cancer sisters and potential dosage effects implications: a case report.

Published in:

Molecular Biology Reports, 2025, v. 52, n. 1, p. 1, doi. 10.1007/s11033-024-10213-4

By:

Lombardo, Valentina;
Scandurra, Giuseppa;
Pettinato, Angela;
Scaglione, Giovanni Luca;
Scollo, Paolo;
Capoluongo, Ettore D.

Publication type:

Article

Novel modifications of PARP inhibitor veliparib increase PARP1 binding to DNA breaks.

Published in:

Biochemical Journal, 2024, v. 481, n. 6, p. 437, doi. 10.1042/BCJ20230406

By:

Velagapudi, Uday Kiran;
Rouleau-Turcotte, Élise;
Billur, Ramya;
Xuwei Shao;
Patil, Manisha;
Black, Ben E.;
Pascal, John M.;
Talele, Tanaji T.

Publication type:

Article

PARP-1 activation after oxidative insult promotes energy stress-dependent phosphorylation of YAP1 and reduces cell viability.

Published in:

Biochemical Journal, 2020, v. 477, n. 23, p. 4491, doi. 10.1042/BCJ20200525

By:

Martín-Guerrero, Sandra M.;
Casado, Pedro;
Hijazi, Maruan;
Rajeeve, Vinothini;
Plaza-Díaz, Julio;
Abadía-Molina, Francisco;
Navascués, Julio;
Cuadros, Miguel A.;
Cutillas, Pedro R.;
Martín-Oliva, David

Publication type:

Article

Nanoparticles-SIRT1 Prevents Endothelial Progenitor Cells Senescence by Modulating Nitric Oxide Expression and Reducing Poly ADP-ribose Polymerase: In vitro Study.

Published in:

Trends in Sciences, 2024, v. 21, n. 6, p. 1, doi. 10.48048/tis.2024.7519

By:

Wihastuti, Titin Andri;
Chomsy, Indah Nur;
Nurwidyaningtyas, Wiwit;
Cesa, Fibe Yulinda;
Sujuti, Hidayat;
Setiawan, Meddy;
Kumboyono, Kumboyono

Publication type:

Article

PARP1 bound to XRCC2 promotes tumor progression in colorectal cancer.

Published in:

Discover Oncology, 2024, v. 15, n. 1, p. 1, doi. 10.1007/s12672-024-01112-y

By:

Xu, Kaiwu;
Yu, Zhige;
Lu, Tailiang;
Peng, Wei;
Gong, Yongqiang;
Chen, Chaowu

Publication type:

Article

Convergent evolution of BRCA2 reversion mutations under therapeutic pressure by PARP inhibition and platinum chemotherapy.

Published in:

NPJ Precision Oncology, 2024, v. 8, p. 1, doi. 10.1038/s41698-024-00526-9

By:

Walmsley, Charlotte S.;
Jonsson, Philip;
Cheng, Michael L.;
McBride, Sean;
Kaeser, Christopher;
Vargas, Herbert Alberto;
Laudone, Vincent;
Taylor, Barry S.;
Kappagantula, Rajya;
Baez, Priscilla;
Richards, Allison L.;
Noronha, Anne Marie;
Perera, Dilmi;
Berger, Michael;
Solit, David B.;
Iacobuzio-Donahue, Christine A.;
Scher, Howard I.;
Donoghue, Mark T. A.;
Abida, Wassim;
Schram, Alison M.

Publication type:

Article

Dual function of HPF1 in the modulation of PARP1 and PARP2 activities.

Published in:

Communications Biology, 2021, v. 4, n. 1, p. 1, doi. 10.1038/s42003-021-02780-0

By:

Kurgina, Tatyana A.;
Moor, Nina A.;
Kutuzov, Mikhail M.;
Naumenko, Konstantin N.;
Ukraintsev, Alexander A.;
Lavrik, Olga I.

Publication type:

Article

Modulatory effect of Persea Americana oil against diethylnitrosamine-induced hepatotoxicity in rats: a proposed mechanism.

Published in:

Bulletin of the National Research Centre, 2021, v. 45, n. 1, p. 1, doi. 10.1186/s42269-021-00653-4

By:

Abozaid, Omayma A. R.;
Anees, Lobna M.;
Abdel-Hamed, Gehan R.

Publication type:

Article

Rethinking the use of germline CHEK2 mutation as a marker for PARP inhibitor sensitivity.

Published in:

JNCI Cancer Spectrum, 2024, v. 8, n. 4, p. 1, doi. 10.1093/jncics/pkae045

By:

Hayman, Thomas J

Publication type:

Article

草苁蓉多糖对氧化损伤致血管内皮细胞凋亡相关蛋白表达的影响.

Published in:

Food Research & Development, 2020, v. 41, n. 22, p. 162, doi. 10.12161/j.issn.1005-6521.2020.22.027

By:

刘莉园;
张天;
张钊;
崔香丹;
尹学哲;
全吉淑

Publication type:

Article

Pitavastatin induces caspase‐mediated apoptotic death through oxidative stress and DNA damage in combined with cisplatin in human cervical cancer cell line.

Published in:

Journal of Applied Toxicology, 2024, v. 44, n. 4, p. 623, doi. 10.1002/jat.4565

By:

Hacıseyitoğlu, Aysun Ökçesiz;
Doğan, Tuğbagül Çal;
Dilsiz, Sevtap Aydın;
Canpınar, Hande;
Eken, Ayşe;
Bucurgat, Ülkü Ündeğer

Publication type:

Article

Histone demethylase JHDM2A regulates H3K9 dimethylation in response to arsenic‐induced DNA damage and repair in normal human liver cells.

Published in:

Journal of Applied Toxicology, 2020, v. 40, n. 12, p. 1661, doi. 10.1002/jat.4026

By:

Zhang, An‐liu;
Tang, Shun‐fang;
Yang, Yue;
Li, Chang‐zhe;
Ding, Xue‐jiao;
Zhao, Hua;
Wang, Jun‐hua;
Yang, Guang‐hong;
Li, Jun

Publication type:

Article

PARP Inhibitors as a Therapeutic Agent for Homologous Recombination Deficiency in Breast Cancers.

Published in:

Journal of Clinical Medicine, 2019, v. 8, n. 4, p. 435, doi. 10.3390/jcm8040435

By:

Keung, Man Yee T.;
Wu, Yanyuan;
Vadgama, Jaydutt V.

Publication type:

Article

Evaluation of the role of oxidative stress in the anticancer effects of CHK1 and PARP-1 inhibitors in HepG2 cells: POST-CONFERENCE REPORT.

Published in:

Acta Universitatis Lodziensis Folia Biologica et Oecologica, 2024, v. 18, p. 7, doi. 10.18778/1730-2366.18.02

By:

BĘBENEK, WIKTORIA;
MARCZAK, AGNIESZKA;
ROGALSKA, ANETA

Publication type:

Article

Inhibition of efflux transporters by poly ADP‐ribose polymerase inhibitors.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2023, v. 133, n. 4, p. 428, doi. 10.1111/bcpt.13928

By:

Deng, Feng;
Sistonen, Johanna;
Neuvonen, Mikko;
Niemi, Mikko

Publication type:

Article

Role of Poly(ADP-Ribose) Polymerase (PARP) Enzyme in the Systemic Acquired Acclimation Induced by Light Stress in Phaseolus vulgaris L. Plants.

Published in:

Plants (2223-7747), 2022, v. 11, n. 14, p. N.PAG, doi. 10.3390/plants11141870

By:

Vitale, Luca;
Vitale, Ermenegilda;
Bianchi, Anna Rita;
De Maio, Anna;
Arena, Carmen

Publication type:

Article

Photo-Protective Mechanisms and the Role of Poly (ADP-Ribose) Polymerase Activity in a Facultative CAM Plant Exposed to Long-Term Water Deprivation.

Published in:

Plants (2223-7747), 2020, v. 9, n. 9, p. 1192, doi. 10.3390/plants9091192

By:

Vitale, Luca;
Vitale, Ermenegilda;
Costanzo, Giulia;
De Maio, Anna;
Arena, Carmen

Publication type:

Article

PARP inhibition in ovarian cancer: what is still missing?

Published in:

European Journal of Gynaecological Oncology, 2022, v. 43, n. 1, p. 143, doi. 10.31083/j.ejgo4301016

By:

Morotti, Matteo;
Ghisoni, Eleonora

Publication type:

Article

Surgical and systemic therapies for addressing occult disease in advanced epithelial ovarian cancer.

Published in:

European Journal of Gynaecological Oncology, 2022, v. 43, n. 1, p. 87, doi. 10.31083/j.ejgo4301005

By:

Bhatt, Aditi;
Sinukumar, Snita;
Kammar, Praveen;
Mehta, Sanket

Publication type:

Article

The role of PARP inhibitors in ovarian cancer: therapeutic mechanisms and clinical data.

Published in:

European Journal of Gynaecological Oncology, 2021, v. 42, n. 2, p. 199, doi. 10.31083/j.ejgo.2021.02.2205

By:

Moo-Kon Song

Publication type:

Article

Wheat SIMILAR TO RCD-ONE Gene Enhances Seedling Growth and Abiotic Stress Resistance by Modulating Redox Homeostasis and Maintaining Genomic Integrity.

Published in:

Plant Cell, 2014, v. 26, n. 1, p. 164, doi. 10.1105/tpc.113.118687

By:

Liu, Shuantao;
Liu, Shuwei;
Wang, Mei;
Wei, Tiandi;
Meng, Chen;
Wang, Meng;
Xia, Guangmin

Publication type:

Article

PLK1 inhibition leads to mitotic arrest and triggers apoptosis in cholangiocarcinoma cells.

Published in:

Oncology Letters, 2024, v. 28, n. 1, p. N.PAG, doi. 10.3892/ol.2024.14449

By:

Moolmuang, Benchamart;
Chaisaingmongkol, Jittiporn;
Singhirunnusorn, Pattama;
Ruchirawat, Mathuros

Publication type:

Article

Transporter‑mediated drug‑drug interactions involving poly (ADP‑ribose) polymerase inhibitors (Review).

Published in:

Oncology Letters, 2023, v. 25, n. 4, p. N.PAG, doi. 10.3892/ol.2023.13747

By:

Zhao, Dehua;
Long, Xiaoqing;
Wang, Jisheng

Publication type:

Article

Macamide B suppresses lung cancer progression potentially via the ATM signaling pathway.

Published in:

Oncology Letters, 2023, v. 25, n. 3, p. N.PAG, doi. 10.3892/ol.2023.13701

By:

Tao, Haiyan;
Shi, Hubo;
Wang, Min;
Xu, Yihui

Publication type:

Article

Targeting SIRT1 to inhibit the proliferation of multiple myeloma cells.

Published in:

Oncology Letters, 2021, v. 21, n. 4, p. N.PAG, doi. 10.3892/ol.2021.12567

By:

Lu, Bo;
Zhang, Dengyang;
Wang, Xiaobo;
Lin, Dongjun;
Chen, Yun;
Xu, Xiaojun

Publication type:

Article

Lycorine hydrochloride induces reactive oxygen species-mediated apoptosis via the mitochondrial apoptotic pathway and the JNK signaling pathway in the oral squamous cell carcinoma HSC-3 cell line.

Published in:

Oncology Letters, 2021, v. 21, n. 3, p. N.PAG, doi. 10.3892/ol.2021.12497

By:

Li, Min-Hui;
Liao, Xin;
Li, Chen;
Wang, Tian-Tian;
Sun, Yi-Song;
Yang, Kang;
Jiang, Pei-Wen;
Shi, Song-Ting;
Zhang, Wen-Xin;
Zhang, Kun;
Li, Chao;
Yang, Ping

Publication type:

Article

TERT promoter regulating melittin expression induces apoptosis and G0/G1 cell cycle arrest in esophageal carcinoma cells.

Published in:

Oncology Letters, 2021, v. 21, n. 1, p. N.PAG

By:

Zhou, Chao;
Ma, Jie;
Lu, Yuanhua;
Zhao, Wan;
Xu, Bingxue;
Lin, Jian;
Ma, Yongjun;
Tian, Yafei;
Zhang, Qi;
Wang, Wei;
Yan, Weiqun;
Jiao, Ping

Publication type:

Article

Apoptosis-mediated antiproliferation of A549 lung cancer cells mediated by Eugenia aquea leaf compound 2′,4′-dihydroxy-6′-methoxy-3′,5′-dimethylchalcone and its molecular interaction with caspase receptor in molecular docking simulation

Published in:

Oncology Letters, 2020, v. 19, n. 5, p. 3551, doi. 10.3892/ol.2020.11466

By:

Hadisaputri, Yuni Elsa;
Cahyana, Noni;
Muchtaridi, Muchtaridi;
Lesmana, Ronny;
Rusdiana, Taofik;
Chaerunisa, Anis Yohana;
Sufiawati, Irna;
Rostinawati, Tina;
Subarnas, Anas

Publication type:

Article

Sasa quelpaertensis Nakai extract induces p53-independent apoptosis via the elevation of nitric oxide production in human HCT116 colon cancer cells.

Published in:

Oncology Letters, 2020, v. 19, n. 4, p. 3027, doi. 10.3892/ol.2020.11379

By:

MIN YOUNG KIM

Publication type:

Article

Pharmacological ascorbate induces 'BRCAness' and enhances the effects of Poly(ADP-Ribose) polymerase inhibitors against BRCA1/2 wild-type ovarian cancer.

Published in:

Oncology Letters, 2020, v. 19, n. 4, p. 2629, doi. 10.3892/ol.2020.11364

By:

YAN MA;
PING CHEN;
DRISKO, JEANNE A.;
KHABELE, DINEO;
GODWIN, ANDREW K.;
QI CHEN

Publication type:

Article

Cardamonin as a potential treatment for melanoma induces human melanoma cell apoptosis.

Published in:

Oncology Letters, 2020, v. 19, n. 2, p. 1393, doi. 10.3892/ol.2019.11242

By:

Yue, Yuyang;
Liu, Lijuan;
Liu, Peipei;
Li, Yuting;
Lu, Haitao;
Li, Yanjia;
Zhang, Guoqiang;
Duan, Xinsuo

Publication type:

Article

The modulation study of multiple drug resistance in bladder cancer by curcumin and resveratrol.

Published in:

Oncology Letters, 2019, v. 18, n. 6, p. 6869, doi. 10.3892/ol.2019.11023

By:

Cho, Chun-Jung;
Yang, Ching-Wei;
Wu, Chia-Lun;
Ho, Jar-Yi;
Yu, Cheng-Ping;
Wu, Sheng-Tang;
Yu, Dah-Shyong

Publication type:

Article

Artesunate and sorafenib: Combinatorial inhibition of liver cancer cell growth.

Published in:

Oncology Letters, 2019, v. 18, n. 5, p. 4735, doi. 10.3892/ol.2019.10810

By:

Li, Hao;
Xu, Kanghe;
Pian, Guangzhe;
Sun, Shu

Publication type:

Article

Effects of ABT-737 combined with irradiation treatment on uterine cervical cancer cells.

Published in:

Oncology Letters, 2019, v. 18, n. 4, p. 4328, doi. 10.3892/ol.2019.10755

By:

Shen, Huang-Pin;
Wu, Wen-Jun;
Ko, Jiunn-Liang;
Wu, Tzu-Fan;
Yang, Shun-Fa;
Wu, Chih-Hsien;
Yeh, Chia-Ming;
Wang, Po-Hui

Publication type:

Article

Tanshinone IIA inhibits proliferation and induces apoptosis of human nasopharyngeal carcinoma cells via p53-cyclin B1/CDC2.

Published in:

Oncology Letters, 2019, v. 18, n. 3, p. 3317, doi. 10.3892/ol.2019.10658

By:

Liu, Bin;
Liu, Lixia;
Zang, Aimin;
Song, Zizheng;
Yang, Hua;
Wang, Zhiyu;
Shang, Yanhong;
Ma, Tao;
Zhang, Yonggang

Publication type:

Article

Pro-apoptotic effect of the novel benzylidene derivative MHY695 in human colon cancer cells.

Published in:

Oncology Letters, 2019, v. 18, n. 3, p. 3256, doi. 10.3892/ol.2019.10664

By:

Heo, Gwangbeom;
Kang, Dongwan;
Park, Chaeun;
Kim, Su Jin;
Choo, Jieun;
Lee, Yunna;
Yoo, Jin-Wook;
Jung, Yunjin;
Lee, Jaewon;
Kim, Nam Deuk;
Chung, Hae Young;
Moon, Hyung Ryong;
Im, Eunok

Publication type:

Article

MicroRNA-410-3p upregulation suppresses proliferation, invasion and migration, and promotes apoptosis in rhabdomyosarcoma cells.

Published in:

Oncology Letters, 2019, v. 18, n. 1, p. 936, doi. 10.3892/ol.2019.10345

By:

Zhang, Liang;
Pang, Yuwen;
Cui, Xiaobin;
Jia, Wei;
Cui, Wenwen;
Liu, Yang;
Liu, Chunxia;
Li, Feng

Publication type:

Article

Combinatorial therapy of immune checkpoint and cancer pathways provides a novel perspective on ovarian cancer treatment.

Published in:

Oncology Letters, 2019, v. 17, n. 3, p. 2583

By:

Zhang, Guyu;
Liu, Chongdong;
Bai, Huiming;
Cao, Guangming;
Cui, Ran;
Zhang, Zhengyu

Publication type:

Article

Deubiquitinating enzyme 4 facilitates chemoresistance in glioblastoma by inhibiting P53 activity.

Published in:

Oncology Letters, 2019, v. 17, n. 1, p. 958

By:

Qin, Na;
Han, Fengli;
Li, Li;
Ge, Yingwei;
Lin, Wei;
Wang, Jiang;
Wu, Lin;
Zhao, Gang;
Deng, Yanchun;
Zhang, Jian

Publication type:

Article

Su Yang Decoction induces human colon carcinoma cell apoptosis by activating caspases.

Published in:

Oncology Letters, 2019, v. 17, n. 1, p. 422

By:

Ge, Yazhong;
Gao, Qing;
Yan, Fengjiao;
Zhang, Xiaona;
Liu, Yurong;
Zhou, Yi

Publication type:

Article

Knockdown of DNA/RNA-binding protein KIN17 promotes apoptosis of triple-negative breast cancer cells.

Published in:

Oncology Letters, 2019, v. 17, n. 1, p. 288

By:

Gao, Xiang;
Liu, Zhenping;
Zhong, Meifeng;
Wu, Kunhe;
Zhang, Yuzhao;
Wang, Hongmei;
Zeng, Tao

Publication type:

Article

Poly (ADP-ribose) polymerase-1 inhibition decreases proliferation through G2/M arrest in esophageal squamous cell carcinoma.

Published in:

Oncology Letters, 2017, v. 14, n. 2, p. 1581, doi. 10.3892/ol.2017.6334

By:

MASAAKI YAMAMOTO;
MAKOTO YAMASAKI;
YUKIKO TSUKAO;
KOJI TANAKA;
YASUHIRO MIYAZAKI;
TOMOKI MAKINO;
TSUYOSHI TAKAHASHI;
YUKINORI KUROKAWA;
KIYOKAZU NAKAJIMA;
SHUJI TAKIGUCHI;
MASAKI MORI;
YUICHIRO DOKI

Publication type:

Article

PARP inhibition sensitizes endometrial cancer cells to paclitaxel-induced apoptosis.

Published in:

Oncology Letters, 2017, v. 13, n. 4, p. 2847, doi. 10.3892/ol.2017.5795

By:

DINKIC, CHRISTINE;
JAHN, FRIEDERIKE;
ZYGMUNT, MAREK;
SCHUETZ, FLORIAN;
ROM, JOACHIM;
SOHN, CHRISTOF;
FLUHR, HERBERT

Publication type:

Article

Glaucocalyxin A inhibits the growth of liver cancer Focus and SMMC-7721 cells.

Published in:

Oncology Letters, 2016, v. 11, n. 2, p. 1173, doi. 10.3892/ol.2015.4002

By:

LISHA TANG;
XIAOFENG JIN;
XIAOHUI HU;
XIAODING HU;
ZULONG LIU;
LONG YU

Publication type:

Article

PARP Inhibitors in Metastatic Castration-Resistant Prostate Cancer: Unraveling the Therapeutic Landscape.

Published in:

Life (2075-1729), 2024, v. 14, n. 2, p. 198, doi. 10.3390/life14020198

By:

Al-Akhras, Ashaar;
Hage Chehade, Chadi;
Narang, Arshit;
Swami, Umang

Publication type:

Article

Cost-Effectiveness of Genomic Test-Directed Olaparib for Metastatic Castration-Resistant Prostate Cancer.

Published in:

Frontiers in Pharmacology, 2021, v. 11, p. N.PAG, doi. 10.3389/fphar.2020.610601

By:

Su, Dan;
Wu, Bin;
Shi, Lizheng

Publication type:

Article

Editorial: Delivery of Locally-Acting Agents to Intracellular Targets.

Published in:

2020

By:

Rosenkranz, Andrey A.;
Salomone, Salvatore;
Sobolev, Alexander S.

Publication type:

Editorial