Works matching DE "PHARMACEUTICAL chemistry"

Results: 5000

Antimicrobial activity of isoxazole derivatives: A brief overview.

Published in:

Vietnam Journal of Chemistry, 2025, v. 63, n. 2, p. 195, doi. 10.1002/vjch.202400029

By:

Vashisht, Ketan;
Sethi, Pooja;
Bansal, Anshul;
Bansal, Poonam

Publication type:

Article

Efficient synthesis and characterization of imidazo[1,2‐a]pyridine‐8‐carboxamide derivatives: A promising scaffold for drug development.

Published in:

Vietnam Journal of Chemistry, 2024, v. 62, n. 4, p. 556, doi. 10.1002/vjch.202300362

By:

Bhatt, Keval;
Patel, Dhara;
Rathod, Mrudangsinh;
Patel, Ashish;
Shah, Drashti

Publication type:

Article

Effect of Ultrasonic Pretreatment on the Yield and Antioxidant Property of Salvia nemorosa.

Published in:

Biomedical & Biotechnology Research Journal, 2025, v. 9, n. 2, p. 188, doi. 10.4103/bbrj.bbrj_109_25

By:

Mollaei, Saeed;
Koutahi, Parisa;
Farnia, Poopak

Publication type:

Article

Multi-omics approaches: transforming the landscape of natural product isolation.

Published in:

Functional & Integrative Genomics, 2025, v. 25, n. 1, p. 1, doi. 10.1007/s10142-025-01645-7

By:

Sahana, Soumitra;
Sarkar, Jyotirmay;
Mandal, Sourav;
Chatterjee, Indranil;
Dhar, Susmita;
Datta, Samaresh;
Mondal, Sumanta

Publication type:

Article

The Novel SSTR3 Full Agonist ITF2984 Shows Antitumor Properties against Pancreatic Neuroendocrine Tumors.

Published in:

Neuroendocrinology, 2025, v. 115, n. 5, p. 446, doi. 10.1159/000543136

By:

Bistika, Margarita;
Marangelo, Alessandro;
Ascione, Francesco;
Valentini, Nicole;
Fedeli, Francesco;
Schrader, Jörg;
Modena, Daniela;
Steinkühler, Christian;
Pellegata, Natalia S.

Publication type:

Article

Jiao San Xian granule containing prebiotic alleviate functional dyspepsia by regulating intestinal flora and the secretion of inflammatory response.

Published in:

Journal of Food & Drug Analysis, 2025, v. 33, n. 2, p. 106, doi. 10.38212/2224-6614.3541

By:

Huimin Pei;
Mengyuan Zhao;
Hongyue Wang;
Xindi Zhang;
Caihong Shi;
Xiangrong Zhang

Publication type:

Article

Integrating network analysis and experimental validation to reveal the ferroptosis-associated mechanism of velvet antler in the treatment of chronic atrophic gastritis.

Published in:

Journal of Food & Drug Analysis, 2025, v. 33, n. 2, p. 119, doi. 10.38212/2224-6614.3546

By:

Quan Liao;
Zhenzhen Guo;
Chenchun Ding;
Renjie Zu;
Guoyan Liu

Publication type:

Article

Natural product library screening identifies Darutigenol for the treatment of myocardial infarction and ischemia/reperfusion injury.

Published in:

Chinese Medicine, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13020-025-01141-x

By:

Liu, Kun;
Zheng, Li;
Huang, Qian-Yu;
Li, Hong-Ji;
Li, Cheng;
Zhao, Hui;
Ye, Ze-Bing;
Wang, Hao;
Qi, Xu-Feng;
Wang, Meng

Publication type:

Article

Patent Thickets and Product Hops: Challenges and Opportunities for Legislative Reform.

Published in:

Journal of Law, Medicine & Ethics, 2025, v. 53, n. 1, p. 158, doi. 10.1017/jme.2025.54

By:

Feldman, William B.

Publication type:

Article

Iron‐Catalyzed Reductive Allylic C─H Amination of Olefin with Nitroarenes via Intermolecular Nitroso Ene Reaction.

Published in:

Angewandte Chemie, 2025, v. 137, n. 25, p. 1, doi. 10.1002/ange.202504750

By:

Qi, Shaolong;
Yin, Duren;
Hu, Lingfei;
Huang, Changqin;
Xie, Ruyu;
Lu, Gang;
Wang, Jianchun

Publication type:

Article

Dingzhen pills inhibit neuronal ferroptosis and neuroinflammation by inhibiting the cGAS-STING pathway for Parkinson's disease mice.

Published in:

Chinese Medicine, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13020-025-01135-9

By:

Fu, Gaoshuang;
Li, Ting;
Zhao, Yukun;
Zhang, Shuai;
Xue, Xin;
Yang, Yuqin;
Li, Tingyu;
Luo, Shaohan;
Yue, Guangxin;
Lei, Tong

Publication type:

Article

Structural characterisation of a cysteine-rich conotoxin, sigma(σ)S-GVIIIA, extracted from the defensive venom of the marine cone snail Conus geographus.

Published in:

Biochemical Journal, 2025, v. 482, n. 11, p. 639, doi. 10.1042/BCJ20240753

By:

Yoshimi Peck;
Wilson, David T.;
Lennox-Bulow, Danica;
Giribaldi, Julien;
Seymour, Jamie;
Dutertre, Sebastien;
Rosengren, K. Johan;
Liddell, Michael J.;
Daly, Norelle L.

Publication type:

Article

Scalable and sustainable reductive amidation of nitroarenes, nitroalkenes, and nitroalkyls with acyl saccharins in aqueous media.

Published in:

Communications Chemistry, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42004-025-01464-8

By:

Khamkar, Sunil L.;
Mohan, Rayala;
Santhosh, J.;
Shinde, Harish M.;
Handore, Kishor L.;
Mohan, S. Venkata;
Reddy, D. Srinivasa

Publication type:

Article

Synthesis and Cytotoxic Effects of Various Thiosemicarbazide Compounds on Primary and Metastatic Breast Cancer Cell Lines.

Published in:

Cyprus Journal of Medical Sciences, 2025, v. 10, p. 1, doi. 10.4274/cjms.2025.2024-116

By:

Ensarioğlu, Hilal Kabadayı;
Becer, Eda;
Başoğlu, Faika;
Güzeldemirci, Nuray Ulusoy;
Vatansever, Hafize Seda

Publication type:

Article

Strategy‐Level Prodrug Synthesis.

Published in:

Chemistry - A European Journal, 2025, v. 31, n. 33, p. 1, doi. 10.1002/chem.202501115

By:

Geaneotes, Paul J.;
Floreancig, Paul E.

Publication type:

Article

Multiple intramolecular triggers converge to preferential G protein coupling in the CB<sub>2</sub>R.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-60003-0

By:

Morales-Pastor, Adrian;
Miljuš, Tamara;
Dieguez-Eceolaza, Miguel;
Stępniewski, Tomasz Maciej;
Ledesma-Martin, Vicente;
Heydenreich, Franziska M.;
Flock, Tilman;
Plouffe, Bianca;
Le Gouill, Christian;
Duchaine, Jean;
Sykes, David A.;
Nicholson, Colin;
Koers, Eline J.;
Guba, Wolfgang;
Rufer, Arne C.;
Grether, Uwe;
Bouvier, Michel;
Veprintsev, Dmitry B.;
Selent, Jana

Publication type:

Article

Exploring the Efficacy of Vessilen ® in Treating Bladder Pain Syndrome/Interstitial Cystitis: A Prospective Study.

Published in:

Healthcare (2227-9032), 2025, v. 13, n. 11, p. 1340, doi. 10.3390/healthcare13111340

By:

Palucci, Mariachiara;
Barba, Marta;
Cola, Alice;
Frigerio, Matteo

Publication type:

Article

Nutrient-Driven Antioxidant Interventions for Prevention of Age-Related and Diabetic Cataracts.

Published in:

Nutrients, 2025, v. 17, n. 11, p. 1885, doi. 10.3390/nu17111885

By:

Giglio, Rosa;
Milan, Serena;
Inferrera, Leandro;
Tognetto, Daniele;
D'Esposito, Fabiana;
Visalli, Federico;
Gagliano, Caterina;
Zeppieri, Marco

Publication type:

Article

Base‐Mediated [4+1] Annulation Strategy for Modular Assembly of Alkynyl/Carboxylated Dihydrobenzofurans.

Published in:

European Journal of Organic Chemistry, 2025, v. 28, n. 15, p. 1, doi. 10.1002/ejoc.202401455

By:

Kong, Yangzilin;
Wu, Yinsong;
Liu, Yanan;
Fei, Binbin;
Wu, Mengdi;
Gu, Ni;
Tang, Qiang;
He, Xinwei

Publication type:

Article

Synthesis and Functionalization of Aziridines: A Perspective View from Pharmaceutical Industries.

Published in:

European Journal of Organic Chemistry, 2025, v. 28, n. 15, p. 1, doi. 10.1002/ejoc.202401414

By:

Ju, Xuan;
Lee, Miseon;
Leung, Joyce C.;
Lee, Jaehee

Publication type:

Article

Recent approaches for the synthesis of phosphonopyrroles (microreview).

Published in:

Chemistry of Heterocyclic Compounds, 2025, v. 61, n. 1, p. 48, doi. 10.1007/s10593-025-03395-7

By:

Abaid, Kmar;
Touil, Soufiane

Publication type:

Article

Rationality over convenience: The CDSCO's regulatory ban on irrational antidiabetic fixed-dose combinations in India and its clinical-pharmacological imperatives.

Published in:

International Journal of Diabetes in Developing Countries, 2025, v. 45, n. 2, p. 261, doi. 10.1007/s13410-025-01501-1

By:

Samajdar, Shambo Samrat;
Joshi, Shashank R.;
Husain, Noor;
Bisht, Khushboo;
Venkatraman, Shravan;
Mukherjee, Shatavisa;
Chawla, Rajeev

Publication type:

Article

Development of Water‐Soluble 3‐Nitro‐2‐Pyridinesulfenate for Disulfide Bond Formation of Peptide Under Aqueous Conditions.

Published in:

Chemistry - A European Journal, 2025, v. 31, n. 32, p. 1, doi. 10.1002/chem.202500855

By:

Taguchi, Akihiro;
Sakata, Megumi;
Yamamoto, Ryusei;
Shida, Hayate;
Kuraishi, Saeka;
Konno, Sho;
Takayama, Kentaro;
Taniguchi, Atsuhiko;
Hayashi, Yoshio

Publication type:

Article

Nickel‐Catalyzed Umpolung Difluoroalkylation of Imines Enables General Access to β‐Difluoroalkylated Amines.

Published in:

Angewandte Chemie, 2025, v. 137, n. 24, p. 1, doi. 10.1002/ange.202500990

By:

Tong, Fei‐Fei;
Feng, Xiao‐Tian;
Han, Yuan‐Zhan;
Huang, Ming‐Chen;
Zhao, Hai‐Yang;
Zhang, Xingang

Publication type:

Article

Direct Conversion of Aromatic Lactones into Bioisosteres by Carbonyl‐to‐Boranol Exchange.

Published in:

Angewandte Chemie, 2025, v. 137, n. 24, p. 1, doi. 10.1002/ange.202500921

By:

Zhang, Yu;
Lu, Hong;
Chang, Jie;
Xu, Peng‐Fei;
Li, Hang;
Jin, Yuan;
Wei, Hao

Publication type:

Article

NMR-driven structure-based drug discovery by unveiling molecular interactions.

Published in:

Communications Chemistry, 2025, v. 8, p. 1, doi. 10.1038/s42004-025-01542-x

By:

Platzer, Gerald;
Mayer, Moriz;
McConnell, Darryl B.;
Konrat, Robert

Publication type:

Article

Exploring the neuroprotective mechanisms of Jiawei Suanzaoren decoction in depression: insights from network pharmacology and molecular docking.

Published in:

BMC Complementary Medicine & Therapies, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12906-025-04939-2

By:

Ma, Ruiting;
Zhang, Wenjing;
Chen, Lixia;
Tong, Lijun

Publication type:

Article

Correction: Comparative study on drug encapsulation and release kinetics in extracellular vesicles loaded with snake venom L - amino acid oxidase.

Published in:

2025

By:

Ramesh, Divya;
Bakkannavar, Shankar M.;
Bhat, Vinutha R.;
Pai, K. Sreedhara Ranganath;
Sharan, Krishna

Publication type:

Correction Notice

Controlling Protein Functionalities With Temporal and Cellular/Subcellular Dimensions of Spatial Resolution With Molecular Photoswitches.

Published in:

Medicinal Research Reviews, 2025, v. 45, n. 4, p. 1142, doi. 10.1002/med.22106

By:

Sahu, Saugata;
Amrutha, Ammathnadu S.;
Tamaoki, Nobuyuki

Publication type:

Article

Comparative Analysis of the Efficacy of Beta-Blockers in the Treatment of Chronic Heart Failure Based on Methods of Attribute Statistics and Drug Interaction Analysis.

Published in:

Pharmaceutical Chemistry Journal, 2025, v. 59, n. 1, p. 86, doi. 10.1007/s11094-025-03367-3

By:

Zhukova, O. V.;
Shimanovsky, N. L.

Publication type:

Article

Water-Soluble Analogs of Palmitoylethanolamide and Its Combination with Adamantane- and Phenylcyclohexyl-Containing Glutamate Blockers.

Published in:

Pharmaceutical Chemistry Journal, 2025, v. 59, n. 1, p. 9, doi. 10.1007/s11094-025-03357-5

By:

Gmiro, V. E.;
Serdyuk, S. E.

Publication type:

Article

Significant Achievements of Experimental Pharmacology and Neurology That Were Not Crowned by Success in the Clinic, and Not Only (Review).

Published in:

Pharmaceutical Chemistry Journal, 2025, v. 59, n. 1, p. 1, doi. 10.1007/s11094-025-03356-6

By:

Mirzoyan, R. S.

Publication type:

Article

A VISIT TO THE MUSEUM OF PHARMACY IN KRAKÓW, POLAND.

Published in:

HerbalGram, 2025, n. 143, p. 34

By:

Gafner, Stefan;
Szopa, Agnieszka;
Rzepiela, Agnieszka

Publication type:

Article

Exploring the wound healing potential of Ixora coccinea and Rhododendron arboreum formulation: integrating experimental and computational approaches.

Published in:

Journal of Complementary & Integrative Medicine, 2025, v. 22, n. 2, p. 304, doi. 10.1515/jcim-2024-0232

By:

Bharathy, Pavithra;
Thanikachalam, Punniyakoti Veeraveedu;
Moses, Allen Christopher;
Balakrishnan, Dinesh Kumar

Publication type:

Article

Flow electrooxidation of chiral alcohols with high enantioselectivity via integrated metal‐organic frameworks and aminoxyl radicals.

Published in:

AIChE Journal, 2025, v. 71, n. 7, p. 1, doi. 10.1002/aic.18847

By:

Ren, Linhan;
Li, Jiayuan;
Li, Suiqin;
Li, Kai;
Wang, Yuhang;
Wang, Jieyu;
Chen, Ying;
He, Jiahui;
Zhong, Xing;
Wang, Jianguo

Publication type:

Article

Analytical Study on Physicochemical Synthesis and Biochemical Properties of Schiff Base Complex Compounds.

Published in:

Library of Progress-Library Science, Information Technology & Computer, 2024, v. 44, n. 4, p. 1567

By:

Jain, Namrata;
Moryani, Rajendra

Publication type:

Article

Simultaneous enantioselective determination of 2-, 3-, and 4-methylmethcathinones; their isomers; and major phase-1 metabolites in oral fluid of drug abusers using enantioselective high-performance liquid chromatography-tandem mass spectrometry.

Published in:

Analytical & Bioanalytical Chemistry, 2025, v. 417, n. 15, p. 3231, doi. 10.1007/s00216-025-05838-8

By:

Kobidze, Giorgi;
Faro, Alfredo Fabrizio Lo;
Balloni, Aurora;
Sprega, Giorgia;
Massano, Marta;
Wille, Sarah M. R.;
Basile, Giuseppe;
Farkas, Tivadar;
Tini, Anastasio;
Busardò, Francesco Paolo;
Chankvetadze, Bezhan

Publication type:

Article

Imidazole Hybrids: A Privileged Class of Heterocycles in Medicinal Chemistry with New Insights into Anticancer Activity.

Published in:

Molecules, 2025, v. 30, n. 10, p. 2245, doi. 10.3390/molecules30102245

By:

Murtazaeva, Zarifa;
Nasrullaev, Azizbek;
Buronov, Anvarjon;
Gaybullaev, Shukhrat;
Nie, Lifei;
Numonov, Sodik;
Khushnazarov, Zohidjon;
Turgunov, Davron;
Kuryazov, Rustamkhon;
Zhao, Jiangyu;
Bozorov, Khurshed

Publication type:

Article

High-Risk Neuroblastoma Stage 4 (NBS4): Developing a Medicinal Chemistry Multi-Target Drug Approach.

Published in:

Molecules, 2025, v. 30, n. 10, p. 2211, doi. 10.3390/molecules30102211

By:

Gerges, Amgad;
Canning, Una

Publication type:

Article

Structure-based design of potent and selective inhibitors of the HECT ligase NEDD4.

Published in:

Communications Chemistry, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42004-025-01557-4

By:

Maspero, Elena;
Cappa, Anna;
Weber, Janine;
Trifirò, Paolo;
Amici, Raffaella;
Bruno, Agostino;
Fagà, Giovanni;
Cecatiello, Valentina;
Fattori, Raimondo;
Leuzzi, Brian;
Taibi, Vincenzo;
Meroni, Giuseppe;
Pasi, Maurizio;
Romussi, Alessia;
Sartori, Luca;
Villa, Manuela;
Vultaggio, Stefania;
Cirò, Marco;
Soffientini, Paolo;
Lombardo, Lierin

Publication type:

Article

A Path Forward for Extended-Release Buprenorphine—Optimizing Implementation Strategies.

Published in:

2025

By:

Assoumou, Sabrina A.;
Morgan, Jake R.

Publication type:

Opinion

Efficient Synthesis of Tetrasubstituted Furans via Lipase-Catalyzed One-Pot Sequential Multicomponent Reaction.

Published in:

Catalysts (2073-4344), 2025, v. 15, n. 5, p. 482, doi. 10.3390/catal15050482

By:

Zeng, Yongqi;
Tang, Yong;
Xu, Minglu;
Wang, Dantong;
Wang, Zhi;
Gao, Yin;
Wang, Lei

Publication type:

Article

Recent Advances in the Synthesis of Quinolines: A Focus on Oxidative Annulation Strategies.

Published in:

Catalysts (2073-4344), 2025, v. 15, n. 5, p. 441, doi. 10.3390/catal15050441

By:

Liao, Mao-Lin;
Liu, Peng-Peng;
Yang, Jia-Cheng;
Li, Ping-Gui;
Zou, Liang-Hua

Publication type:

Article

Unveiling the Reaction Pathway of Oxidative Aldehyde Deformylation by a MOF-Based Cytochrome P450 Mimic.

Published in:

Catalysts (2073-4344), 2025, v. 15, n. 5, p. 436, doi. 10.3390/catal15050436

By:

Luo, Zehua;
Zhou, Wentian;
Chen, Junying;
Li, Yingwei

Publication type:

Article

Illuminating innovation: the AAPS Open editorial series of AAPS fellows and awardees.

Published in:

2025

By:

Su, Yongchao;
Ronaldson, Patrick;
Kumar, M. N. V. Ravi

Publication type:

Editorial

Nanoparticles and Nanomaterials: A Review from the Standpoint of Pharmacy and Medicine.

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 655, doi. 10.3390/pharmaceutics17050655

By:

Petrov, Gleb V.;
Koldina, Alena M.;
Ledenev, Oleg V.;
Tumasov, Vladimir N.;
Nazarov, Aleksandr A.;
Syroeshkin, Anton V.

Publication type:

Article

Self-Assembled Cannabigerol-Based Nanoparticles: Design, Synthesis, and Antiproliferative Activity.

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 636, doi. 10.3390/pharmaceutics17050636

By:

Amenta, Arianna;
Nordio, Giulia;
Piazzola, Francesco;
Di Paolo, Maria Luisa;
Milani, Fabio;
Giacomini, Martina;
Citarella, Andrea;
Ciriello, Umberto;
Paladino, Giuseppe;
Pellegrino, Sara;
Silvestri, Federica;
Fasano, Valerio;
Dalla Via, Lisa;
Passarella, Daniele

Publication type:

Article

From Patterns to Pills: How Informatics Is Shaping Medicinal Chemistry.

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 612, doi. 10.3390/pharmaceutics17050612

By:

Trachtenberg, Alexander;
Akabayov, Barak

Publication type:

Article

Medicinal Chemistry Strategies in Targeting TGF-βR1 Kinase Domain: Unveiling Insights into Inhibitor Structure–Activity Relationship (SAR).

Published in:

Pharmaceuticals (14248247), 2025, v. 18, n. 5, p. 716, doi. 10.3390/ph18050716

By:

Babiker, Nusaiba A.;
Nadeem, Soam;
Abu Kariem, Hasan;
Abdul Hameed, Afra;
Negmeldin, Ahmed T.;
El-labbad, Eman M.

Publication type:

Article

Nitropyridines in the Synthesis of Bioactive Molecules.

Published in:

Pharmaceuticals (14248247), 2025, v. 18, n. 5, p. 692, doi. 10.3390/ph18050692

By:

Starosotnikov, Alexey;
Bastrakov, Maxim

Publication type:

Article