New Insights into the Biology of the Emerging Tembusu Virus.

Hamel, Rodolphe; Phanitchat, Thipruethai; Wichit, Sineewanlaya; Morales Vargas, Ronald Enrique; Jaroenpool, Jiraporn; Diagne, Cheikh Tidiane; Pompon, Julien; Missé, Dorothée

Reported for the first time in 1955 in Malaysia, Tembusu virus (TMUV) remained, for a long time, in the shadow of flaviviruses with human health importance such as dengue virus or Japanese encephalitis virus. However, since 2010 and the first large epidemic in duck farms in China, the threat of its emergence on a large scale in Asia or even its spillover into the human population is becoming more and more significant. This review aims to report current knowledge on TMUV from viral particle organization to the development of specific vaccines and therapeutics, with a particular focus on host-virus interactions.

MALAYSIA; JAPANESE encephalitis viruses; DENGUE viruses; FLAVIVIRUSES; BIOLOGY; VACCINE development; VIRUSES; DUCK plague

Pathogens, 2021, Vol 10, Issue 8, p1010

2076-0817

Academic Journal

10.3390/pathogens10081010