Works matching DE "ANIMAL experimentation"

Results: 5000

Ex vivo stimulation of the trigeminal nucleus caudalis induces peripheral CGRP release in the trigeminal ganglion and reveals a distinct dopamine–endocannabinoid mechanism relevant to migraine.

Published in:

Journal of Headache & Pain, 2025, v. 26, n. 1, p. 1, doi. 10.1186/s10194-025-02072-6

By:

Christiansen, Isabella Mai;
Reducha, Philip Victor;
Edvinsson, Lars;
Holm, Anja;
Haanes, Kristian Agmund

Publication type:

Article

Screening and identification of the H1R antagonists from natural products by BODIPY FL histamine recognition and DPHD-anchored bombardment coupled with target cell extraction.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1601384

By:

Li, Xinqi;
Hu, Guizhou;
Chen, Xu;
Di, Can;
Qi, Jin

Publication type:

Article

Molecular targets and mechanisms of cortex mori for lung cancer treatment: a network pharmacology study, molecular docking and in vitro and in vivo experimental validation.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1587856

By:

Shao, Ying-Ying;
Yang, Qiu-Hong;
He, Shu-Fen;
Zhang, Han-Bin;
Han, Wei-Chao;
Xie, Bao-Cheng;
He, Rui-Rong;
Hong, Wen-Xin

Publication type:

Article

Pig as Pre‐Clinical Animal Model for Research on Temporomandibular Joint Surgery: A Systematic Review.

Published in:

Journal of Oral Rehabilitation, 2025, v. 52, n. 7, p. 1111, doi. 10.1111/joor.13995

By:

Guignardat, Jean‐François;
Barry, Florent;
Nicot, Romain

Publication type:

Article

Therapeutic potential of miR-204-5p in intervertebral disc degeneration: targeting the SSRP1/NF-κB pathway to inhibit apoptosis.

Published in:

Journal of Orthopaedic Surgery & Research, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13018-025-05999-3

By:

Zhao, Chenhao;
Li, Qiuwei;
Shen, Cailiang

Publication type:

Article

Use of human and animal amniotic membranes in local antibiotic therapy.

Published in:

Journal of Wound Care, 2025, v. 34, n. 6, p. 444, doi. 10.12968/jowc.2022.0088

By:

Klama-Baryła, Agnieszka;
Sitkowska, Anna;
Tomanek, Ewa;
Łabuś, Wojciech;
Smętek, Wojciech;
Kitala, Diana;
Głogowska, Magdalena;
Kucharzewski, Marek

Publication type:

Article

The analgesic mechanism of electroacupuncture at the central level for neuropathic pain: a review of studies based on animal experiments.

Published in:

Frontiers in Neurology, 2025, p. 1, doi. 10.3389/fneur.2025.1587471

By:

Qi, Pengfei;
Li, Quan;
Han, Mingyuan;
Cui, Yang;
Zhou, Xinyu;
Sun, Zhongren;
Ding, Shuo;
Yu, Mengdi;
Zhang, Hongbo;
Yin, Hongna

Publication type:

Article

HNF4A promotes tumor progression in gastric cancer by transcriptional activation of KIF2C.

Published in:

Clinical & Experimental Medicine, 2025, v. 25, n. 1, p. 1, doi. 10.1007/s10238-025-01748-2

By:

Lu, Hao;
Gan, Jin-heng;
Zhou, Li-qiang;
Yuan, Yi-Wu;
Zhou, Qi;
Xin, Lin

Publication type:

Article

CLIC1 Supports Mechanisms Related to Platelet Activation and Thrombosis.

Published in:

Transfusion Medicine & Hemotherapy, 2025, v. 52, n. 3, p. 178, doi. 10.1159/000544115

By:

Knowles, Lynn M.;
Ampofo, Emmanuel;
Menger, Michael D.;
Drawz, Anna;
Eichler, Hermann;
Pilch, Jan

Publication type:

Article

Investigation of Behavioral Changes and Histopathological Changes in the Brain in Alzheimer's Modeled Mice with Aluminium Chloride (AlCl3).

Published in:

Cyprus Journal of Medical Sciences, 2025, v. 10, p. 1, doi. 10.4274/cjms.2024.2024-123

By:

Kanan, Derya Deniz;
Aydemir, Işıl;
Alizade, Ares;
Ebrahimi, Sonia;
Aksu, Fazilet

Publication type:

Article

In Vivo Assessment of a Capsaicin-Containing Microemulsion for Neuropathic Pain Management.

Published in:

Cyprus Journal of Medical Sciences, 2025, v. 10, p. 1, doi. 10.4274/cjms.2024.2024-129

By:

Shayyah, Rumooz;
Bölgen, Umay Merve Güven;
Alizade, Ares;
Kayıran, Serpil Demirci;
Ebrahimi, Sonia;
Aksu, Fazilet

Publication type:

Article

Development of a qRT - PCR Diagnostic Kit for the Detection of FCoV.

Published in:

Cyprus Journal of Medical Sciences, 2025, v. 10, p. 1, doi. 10.4274/cjms.2025.2024-136

By:

Dereboylu, Gülten Tuncel;
Akan, Gökçe;
Kalaycı, Melis;
Özverel, Cenk Serhan;
Şanlıdağ, Tamer

Publication type:

Article

Adipose Mesenchymal Stem Cell-Derived Exosomes Prevent Testicular Torsion Injury by Controlling Apoptosis and Necroptosis.

Published in:

Cyprus Journal of Medical Sciences, 2025, v. 10, p. 1, doi. 10.4274/cjms.2025.2024-124

By:

Ensarioğlu, Hilal Kabadayı;
Şimşek, Fatma Bilgecan;
Vatansever, Hafize Seda;
Çayırlı, Hasan;
Şencan, Aydın

Publication type:

Article

Ancylostomiasis Prevalence in Carnivores of Iran: A Systematic Review and Meta-Analysis.

Published in:

International Archives of Health Sciences, 2025, v. 12, n. 1, p. 60, doi. 10.48307/iahsj.2024.448934.1162

By:

Hajinaghi, Mohammad Javad;
Moslemi, Azam;
Ghasemikhah, Reza

Publication type:

Article

Mechanisms of alleviating sepsis-induced rat lung and kidney damage by inhibiting expression of miRNA-939.

Published in:

Folia Histochemica et Cytobiologica, 2025, v. 63, n. 2, p. 88, doi. 10.5603/fhc.101988

By:

Anwaier Apizi;
Jian Li;
Yan Li;
Zhaoxia Yu;
Ruifeng Chai

Publication type:

Article

Nintedanib alleviates hyperoxia-induced lung injury via targeting NF-?B signalling pathway in rat model of bronchopulmonary dysplasia.

Published in:

Folia Histochemica et Cytobiologica, 2025, v. 63, n. 2, p. 79, doi. 10.5603/fhc.105218

By:

Rui Hao;
Yuping Li;
Junhui Li;
Zirui Guo;
Zhi Yang;
Wei Lu

Publication type:

Article

MiR-494-3p knockdown promotes osteogenic differentiation of bone marrow mesenchymal stem cells in ovariectomised rats by targeting Sirt1/TLR4/NF-?B pathway.

Published in:

Folia Histochemica et Cytobiologica, 2025, v. 63, n. 2, p. 65, doi. 10.5603/fhc.104450

By:

Jianping Lei;
Song Guo;
Jiabing Kuang;
Bo Shen;
Zixi Li

Publication type:

Article

Upregulation of SIRT1 ameliorates apoptosis of rat nucleus pulposus cells under oxidative stress through FoxO1/β-catenin pathway.

Published in:

Folia Histochemica et Cytobiologica, 2025, v. 63, n. 2, p. 53, doi. 10.5603/fhc.104395

By:

Hongtao Hu;
Sheng Wang;
Haijun Teng;
Sishun Zhao;
Weisheng Hong

Publication type:

Article

Long-Term Experiences of Basic Education in Laboratory Animal Science.

Published in:

Animals (2076-2615), 2025, v. 15, n. 11, p. 1541, doi. 10.3390/ani15111541

By:

Küller, Valeria;
Schenkel, Johannes

Publication type:

Article

RNA sequencing uncovers key players of cartilage calcification: potential implications for osteoarthritis pathogenesis Open Access.

Published in:

Rheumatology, 2025, v. 64, n. 5, p. 3151, doi. 10.1093/rheumatology/keae587

By:

Bernabei, Ilaria;
Faure, Elodie;
Wegrzyn, Julien;
Bertheaume, Nicolas;
Falgayrac, Guillaume;
Hugle, Thomas;
Nasi, Sonia;
Busso, Nathalie

Publication type:

Article

Intestinal epithelial expression of human TNF is sufficient to induce small bowel inflammation and sacroiliitis, mimicking human spondyloarthritis.

Published in:

Rheumatology, 2025, v. 64, n. 5, p. 3116, doi. 10.1093/rheumatology/keae507

By:

Debusschere, Karlijn;
Souza, Donald;
Nabozny, Gerald H;
Dumas, Emilie;
Verheugen, Eveline;
Coudenys, Julie;
Manuello, Teddy;
Stappers, Flore;
Decruy, Tine;
Maelegheer, Margaux;
Schryvers, Nadia;
Gilis, Elisabeth;
Elewaut, Dirk

Publication type:

Article

Association of gut commensal translocation with autoantibody production in systemic lupus erythematosus.

Published in:

Rheumatology, 2025, v. 64, n. 5, p. 3104, doi. 10.1093/rheumatology/keae476

By:

Katsushima, Masao;
Nakayama, Yoichi;
Yoshida, Tsuneyasu;
Nishida, Yuri;
Shirakashi, Mirei;
Nakashima, Ran;
Yoshifuji, Hajime;
Ito, Shinji;
Satoh, Junko;
Yamamoto, Masaki;
Watanabe, Ryu;
Emori, Takashi;
Kamiya, Tomonori;
Nitahara, Yuko;
Nakagama, Yu;
Ohtani, Naoko;
Kido, Yasutoshi;
Morinobu, Akio;
Hashimoto, Motomu

Publication type:

Article

The role of secretome in restoring ovarian function: A systematic review and meta-analysis of in vivo studies in mice with premature ovarian insufficiency.

Published in:

Turkish Journal of Obstetrics & Gynecology, 2025, v. 22, n. 2, p. 1, doi. 10.4274/tjod.galenos.2025.57485

By:

Kawilarang, Stella;
Wiratnaya, I Gede Eka;
Yasa, I Wayan Putu Sutirta;
Budiana, I Nyoman Gede

Publication type:

Article

Assessing the potential of nifedipine and resveratrol to enhance ovarian viability in conjunction with detorsion treatment: A rat ovarian torsion model study.

Published in:

Turkish Journal of Obstetrics & Gynecology, 2025, v. 22, n. 2, p. 1, doi. 10.4274/tjod.galenos.2025.30161

By:

Sezgin, Aydan;
Sert, Asiye Aslı Emniyet;
Kaplanoğlu, Gülnur Take;
Karakaya, Cengiz;
Demirdağ, Erhan;
Akdulum, M. Funda Cevher;
Erdem, Mehmet;
Erdem, Ahmet;
Öktem, Mesut

Publication type:

Article

A Triple Oral Combination of Bendamustine, Acalabrutinib, and Venetoclax Demonstrates Efficacy Against Mantle Cell Lymphoma In Vitro and In Vivo.

Published in:

Cancers, 2025, v. 17, n. 11, p. 1889, doi. 10.3390/cancers17111889

By:

Filioglou, Dimitrios;
Santa-Cruz, Nina;
Leite, Geovana S. F.;
Davini, Dan W.;
Cracchiolo, Megan J.;
Baker, Forrest L.;
Husnain, Muhammad;
Simpson, Richard J.;
Voudouris, Vasilios;
Katsanis, Emmanuel

Publication type:

Article

Bone Marrow Myeloid–Lymphatic Progenitors Expand Tumor Lymphatic Vasculature Through Cell Fusion.

Published in:

Cancers, 2025, v. 17, n. 11, p. 1804, doi. 10.3390/cancers17111804

By:

Athaiya, Shaswati;
Volk-Draper, Lisa;
Cox, Emma;
Robinson, Kathy;
Zinkevich, Natalya;
Ran, Sophia

Publication type:

Article

L-Theanine Mitigates Chronic Alcoholic Intestinal Injury by Regulating Intestinal Alcohol and Linoleic-Arachidonic Acid Metabolism in Rats.

Published in:

Nutrients, 2025, v. 17, n. 11, p. 1943, doi. 10.3390/nu17111943

By:

Gu, Jiayou;
Tan, Simin;
Yang, Jiahao;
Dang, Xuhui;
Liu, Kehong;
Gong, Zhihua;
Xiao, Wenjun

Publication type:

Article

Fermented Apple Juice Reduces the Susceptibility of Offspring Mice to Food Allergy Exacerbated by Maternal High-Fat Diet.

Published in:

Nutrients, 2025, v. 17, n. 11, p. 1927, doi. 10.3390/nu17111927

By:

Ma, Jing;
Yu, Jian;
Jia, Yining;
Luo, Zining;
Yang, Xin;
Li, Huzhong;
Long, Fangyu

Publication type:

Article

The Alleviating Effect of Abalone Viscera Collagen Peptide in DSS-Induced Colitis Mice: Effect on Inflammatory Cytokines, Oxidative Stress, and Gut Microbiota.

Published in:

Nutrients, 2025, v. 17, n. 11, p. 1926, doi. 10.3390/nu17111926

By:

Liu, Binxiong;
Liu, Lili;
Li, Chunjiang;
Guo, Tengming;
Li, Changcheng;
Tian, Meiling;
Fang, Ting

Publication type:

Article

Low TAS1R2 Sweet Taste Receptor Expression in Skeletal Muscle of Genetically Diverse BXD Mice Mirrors Transcriptomic Signatures of Loss-of-Function Mice.

Published in:

Nutrients, 2025, v. 17, n. 11, p. 1918, doi. 10.3390/nu17111918

By:

King, Kendall;
Serrano, Joan;
Meshram, Nishita N.;
Saadi, Mahdiye;
Moreira, Lynn;
Papachristou, Evaggelia G.;
Kyriazis, George A.

Publication type:

Article

Aqueous Extract of Freshwater Clam Increases Alcohol Metabolism in Rats in a Preclinical Model.

Published in:

Nutrients, 2025, v. 17, n. 11, p. 1915, doi. 10.3390/nu17111915

By:

Chung, Pei-Ying;
Chiu, I-Chen;
Kuan, Ching-Yi;
Wu, Tsung-Meng;
Tseng, Kuo-Chan;
Chuang, Shu-Ting;
Tsai, Sen-Wei;
Chen, Yu-Kuo

Publication type:

Article

Effect of Alpha-1 Antitrypsin Deficiency on Zinc Homeostasis Gene Regulation and Interaction with Endoplasmic Reticulum Stress Response-Associated Genes.

Published in:

Nutrients, 2025, v. 17, n. 11, p. 1913, doi. 10.3390/nu17111913

By:

Liuzzi, Juan P.;
Gonzales, Samantha;
Barbieri, Manuel A.;
Vidal, Rebecca;
Yoo, Changwon

Publication type:

Article

Exploring the Synergistic Action of Medium-Chain Triglycerides and Omega-3 Fatty Acids to Enhance Cellular Uptake and Anti-Inflammatory Responses.

Published in:

Nutrients, 2025, v. 17, n. 11, p. 1889, doi. 10.3390/nu17111889

By:

Kaminskas Fernandes Isern, Camila;
Chen, Yao;
Touboul, Roni;
Frank, Benjamin;
Hu, Shuchen;
Chang, Chuchun L.

Publication type:

Article

An Isobolographic Analysis of the Antinociceptive Effect of Salvia hispanica L. in Combination with Citrus × latifolia in Rats.

Published in:

Nutrients, 2025, v. 17, n. 11, p. 1884, doi. 10.3390/nu17111884

By:

Chel-Guerrero, Lilian Dolores;
Ortiz-Andrade, Rolffy;
Sauri-Duch, Enrique;
Piña-Betancourt, Emilio;
Hebert-Doctor, Luis;
Déciga-Campos, Myrna

Publication type:

Article

Natural Bicarbonate Water Might Enhance Nitrogen Balance and Lipid Metabolism and Improve Calcium Balance: A Full Quantitative Targeted Metabolomics Study in Rats.

Published in:

Nutrients, 2025, v. 17, n. 11, p. 1875, doi. 10.3390/nu17111875

By:

Luo, Jiaohua;
Wang, Jia;
Qiu, Zhiqun;
Zeng, Hui;
Tan, Yao;
Huang, Yujing;
Shu, Weiqun

Publication type:

Article

The Differential Modulatory Effects of Potassium Supplementation on Blood Pressure, Vascular Reactivity, Glomerular Filtration Rates, and Oxidative Stress in Different Experimental Hypertensive Models.

Published in:

Nutrients, 2025, v. 17, n. 11, p. 1865, doi. 10.3390/nu17111865

By:

Nwokocha, Chukwuemeka R.;
Palacios, Javier;
Reid, Melissa Kaydeen;
Nunes, Nikolai Javier;
Gray, Wesley;
McGrowder, Donovan;
Orie, Nelson N.;
Yakubu, Momoh A.

Publication type:

Article

Efficient Enrichment of Docosahexaenoic Acid (DHA) in Mother's Milk and in the Brain and Retina of the Offspring by Lysophosphatidylcholine (LPC)-DHA in the Maternal Diet.

Published in:

Nutrients, 2025, v. 17, n. 11, p. 1864, doi. 10.3390/nu17111864

By:

Yalagala, Poorna C. R.;
Sugasini, Dhavamani;
Chantapim, Sutape;
Caal, Karyna;
Sun, Haijing;
Nicastro, Sofia;
Sargis, Robert M.;
Gregg, Brigid;
Subbaiah, Papasani V.

Publication type:

Article

Dihydromyricetin May Attenuate Skin Aging as a RAGE Inhibitor.

Published in:

Nutrients, 2025, v. 17, n. 11, p. 1862, doi. 10.3390/nu17111862

By:

Wang, Fei;
Jian, Yuanzhi;
Xia, Fangzhi;
Kuo, Liangchun;
Wang, Junbo

Publication type:

Article

A Murine Model of High Dietary Histamine Intake: Impact on Histamine Contents and Release in Neural and Extraneural Tissues.

Published in:

Nutrients, 2025, v. 17, n. 11, p. 1851, doi. 10.3390/nu17111851

By:

Kuhn, Annette;
Schramm, Jana;
Vogler, Birgit;
Dux, Mária;
de Mora, Fernando;
Messlinger, Karl

Publication type:

Article

Daily Administration of Agmatine Reduced Anxiety-like Behaviors and Neural Responses in the Brains of Male Mice with Persistent Inflammation in the Craniofacial Region.

Published in:

Nutrients, 2025, v. 17, n. 11, p. 1848, doi. 10.3390/nu17111848

By:

Iwamoto, Yuya;
Piriyaprasath, Kajita;
Yusuf, Andi Sitti Hajrah;
Hasegawa, Mana;
Kakihara, Yoshito;
Sato, Tsutomu;
Fujii, Noritaka;
Yamamura, Kensuke;
Okamoto, Keiichiro

Publication type:

Article

Mechanism of Ginsenoside Rg 1 in Regulating the Metabolic Function of Intestinal Flora for the Treatment of High-Purine Dietary Hyperuricemia.

Published in:

Nutrients, 2025, v. 17, n. 11, p. 1844, doi. 10.3390/nu17111844

By:

Sun, Qiang;
Li, Zhiman;
Yu, Yang;
Sun, Yinshi

Publication type:

Article

Non-Celiac Wheat Gluten Sensitivity Model: Effects on Hepatic Morphophysiology of Wistar Rats.

Published in:

Nutrients, 2025, v. 17, n. 11, p. 1842, doi. 10.3390/nu17111842

By:

Duarte, Ana Luiza Russo;
Silva, Gabriela Barone Volce da;
Santa Rosa, Anne Caroline;
Raniero, Ghiovani Zanzotti;
Monteiro, Antonio Roberto Giriboni;
de Souza, Gustavo Henrique;
Sá-Nakanishi, Anacharis Babeto de;
Comar, Jurandir Fernando;
Cuman, Roberto Kenji Nakamura;
Natali, Maria Raquel Marçal

Publication type:

Article

Dissimilar Effects of Selenite and Selenium Nanoparticles on Skeletal Muscle Development Unrelated to GPx1 Activity During Adolescence in Rats.

Published in:

Nutrients, 2025, v. 17, n. 11, p. 1841, doi. 10.3390/nu17111841

By:

Nogales, Fátima;
Pajuelo, Eloísa;
Gallego-López, María del Carmen;
Romero-Herrera, Inés;
Merchán, Francisco;
Carreras, Olimpia;
Ojeda, María Luisa

Publication type:

Article

Dietary Omega-3 PUFAs in Metabolic Disease Research: A Decade of Omics-Enabled Insights (2014–2024).

Published in:

Nutrients, 2025, v. 17, n. 11, p. 1836, doi. 10.3390/nu17111836

By:

Li, Jing;
Lin, Yang-Chi-Dung;
Zuo, Hua-Li;
Huang, Hsi-Yuan;
Zhang, Tao;
Bai, Jin-Wei;
Huang, Hsien-Da

Publication type:

Article

2,5-Dihydroxybenzoic Acid Ameliorates Metabolic Dysfunction-Associated Steatotic Liver Disease by Targeting the CCL2-CCR2 Axis to Reduce Lipid Accumulation.

Published in:

Nutrients, 2025, v. 17, n. 11, p. 1835, doi. 10.3390/nu17111835

By:

Hsiang, Chien-Yun;
Hsu, Kuang-Ting;
Lo, Hsin-Yi;
Hou, Yun-Jhu;
Ho, Tin-Yun

Publication type:

Article

FPAW from Trachinotus ovatus Attenuates Potassium-Oxonate-Induced Hyperuricemia in Mice via Xanthine Oxidase Inhibition and Gut Microbiota Modulation: Molecular Insights and In Vivo Efficacy.

Published in:

Nutrients, 2025, v. 17, n. 11, p. 1831, doi. 10.3390/nu17111831

By:

Xiang, Huan;
Sun-Waterhouse, Dongxiao;
Hu, Xiao;
Hou, Mengfan;
Chen, Shengjun;
Wu, Yanyan;
Zhao, Yongqiang;
Wang, Yueqi

Publication type:

Article

Cooked Bean (Phaseolus vulgaris L.) Consumption Alters Bile Acid Metabolism in a Mouse Model of Diet-Induced Metabolic Dysfunction: Proof-of-Concept Investigation.

Published in:

Nutrients, 2025, v. 17, n. 11, p. 1827, doi. 10.3390/nu17111827

By:

Lutsiv, Tymofiy;
Fitzgerald, Vanessa K.;
Neil, Elizabeth S.;
McGinley, John N.;
Hussan, Hisham;
Thompson, Henry J.

Publication type:

Article

In Preclinical Epilepsy, GLUT1 and GFAP Dysregulation in Cells Surrounding the Third Ventricle, Including Tanycytes, Is Differentially Restored with Ketogenic Diet Treatment.

Published in:

Nutrients, 2025, v. 17, n. 11, p. 1824, doi. 10.3390/nu17111824

By:

Rafiei, Parisa;
Mian, Huda S.;
Iyer, Shruthi H.;
Draves, Samantha B.;
Matthews, Stephanie A.;
Rendon, Daniel E.;
Neesen, Emma J.;
Dunlay, Madeline;
Revis, McKenna;
Glisan, Adrianna L.;
Simeone, Timothy A.;
Simeone, Kristina A.

Publication type:

Article

Cinnamomum cassia Alleviates Neuropsychiatric Lupus in a Murine Experimental Model.

Published in:

Nutrients, 2025, v. 17, n. 11, p. 1820, doi. 10.3390/nu17111820

By:

Maalouly, Georges;
Saliba, Youakim;
Hajal, Joelle;
Zein-El-Din, Anna;
Fakhoury, Luana;
Najem, Rouaa;
Smayra, Viviane;
Nassereddine, Hussein;
Fares, Nassim

Publication type:

Article

Zinc-Enriched Bifidobacterium longum subsp. longum CCFM1195 Alleviates Cutibacterium acnes -Induced Skin Lesions in Mice by Mitigating Inflammatory Responses and Oxidative Stress.

Published in:

Nutrients, 2025, v. 17, n. 11, p. 1803, doi. 10.3390/nu17111803

By:

Gu, Xiangyue;
Wang, Botao;
Zhang, Tianmeng;
Zhang, Qiuxiang;
Mao, Bingyong;
Tang, Xin;
Zhao, Jianxin;
Cui, Shumao

Publication type:

Article