Works matching DE "METFORMIN"

Results: 5000

Peripheral Antinociception Induced by Carvacrol in the Formalin Test Involves the Opioid Receptor-NO-cGMP-K + Channel Pathway.

Published in:

Metabolites (2218-1989), 2025, v. 15, n. 5, p. 314, doi. 10.3390/metabo15050314

By:

Ortiz, Mario I.;
Cariño-Cortés, Raquel;
Fernández-Martínez, Eduardo;
Muñoz-Pérez, Victor Manuel;
Castañeda-Hernández, Gilberto;
González-García, Martha Patricia

Publication type:

Article

Combination of Periodontal Ligament Stem Cells and Metformin via Organic Cation Transporters for Periodontal Regeneration in Rats.

Published in:

Biomolecules (2218-273X), 2025, v. 15, n. 5, p. 663, doi. 10.3390/biom15050663

By:

Qiao, Qingchen;
Zhao, Zeqing;
Sun, Yaxi;
Wang, Jing;
Li, Xiaowei;
Zhang, Li;
Yang, Hao;
Zhang, Ning;
Zhang, Ke;
Bai, Yuxing

Publication type:

Article

Targeting the Electron Transport System for Enhanced Longevity.

Published in:

Biomolecules (2218-273X), 2025, v. 15, n. 5, p. 614, doi. 10.3390/biom15050614

By:

Radovic, Marko;
Gartzke, Lucas P.;
Wink, Simon E.;
van der Kleij, Joris A.;
Politiek, Frouwkje A.;
Krenning, Guido

Publication type:

Article

Topiramate Added to Metformin for Obesity Control in Women With Polycystic Ovary Syndrome.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2025, v. 110, n. 6, p. e1892, doi. 10.1210/clinem/dgae637

By:

Marchesan, Lucas Bandeira;
Silva, Thais Rasia da;
Spritzer, Poli Mara

Publication type:

Article

Postnatal Cardiometabolic Health After Metformin Use in Gestational Diabetes: A Secondary Analysis of the EMERGE Trial.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2025, v. 110, n. 5, p. e1566, doi. 10.1210/clinem/dgae522

By:

Dunne, Fidelma;
Newman, Christine;
Alvarez-Iglesias, Alberto;
O'Shea, Paula;
Devane, Declan;
Gillespie, Paddy;
Egan, Aoife;
O'Donnell, Martin;
Smyth, Andrew

Publication type:

Article

Renal Protective Effect of Metformin in Type 2 Diabetes Patients.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2025, v. 110, n. 5, p. 1224, doi. 10.1210/clinem/dgae477

By:

Wang, Hsi-Hao;
Lin, Sheng-Hsiang;
Hung, Shih-Yuan;
Chiou, Yuan-Yow;
Hsu, Wan-Chia;
Chang, Chih-Min;
Liou, Hung-Hsiang;
Chang, Min-Yu;
Ho, Li-Chun;
Wu, Ching-Fang;
Lee, Yi-Che

Publication type:

Article

Potential Detrimental Interactions Between Metformin and Supplemental Dietary Fiber in Type 2 Diabetes.

Published in:

Journal of Diabetes, 2025, v. 17, n. 5, p. 1, doi. 10.1111/1753-0407.70101

By:

Hall, Rosemary M.;
Parry‐Strong, Amber;
O'Sullivan, David;
Krebs, Jeremy D.;
Gasser, Olivier

Publication type:

Article

Metformin-Induced Apoptosis Is Mediated Through Mitochondrial VDAC1.

Published in:

Pharmaceuticals (14248247), 2025, v. 18, n. 5, p. 757, doi. 10.3390/ph18050757

By:

Shteinfer-Kuzmine, Anna;
Moyal, Meital M.;
Karunanithi Nivedita, Aditya;
Trishna, Sweta;
Nadir, Almog;
Tripathi, Shubhandra;
Shoshan-Barmatz, Varda

Publication type:

Article

Active Constituent of HQS in T2DM Intervention: Efficacy and Mechanistic Insights.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 10, p. 4578, doi. 10.3390/ijms26104578

By:

Chen, Yaping;
Wen, Qiuqi;
Yang, Bing;
Feng, Liang;
Jia, Xiaobin

Publication type:

Article

Quality by Design (QbD) Based Development and Validation of RP-HPLC Method for Simultaneous Estimation of Metformin and Teneligliptin in Bulk and their Pharmaceutical Formulation.

Published in:

Indian Journal of Pharmaceutical Education & Research, 2025, v. 59, p. s689, doi. 10.5530/ijper.20253717

By:

Upadhyay, Jagatkumar;
Padhiyar, Shantilal;
Jivani, Kamlesh;
Patel, Tejas;
Bhavsar, Vashisth;
Prajapati, Vipul

Publication type:

Article

Delaying Renal Aging: Metformin Holds Promise as a Potential Treatment.

Published in:

2025

By:

Qiao Zheng;
Jin Zhao;
Jinguo Yuan;
Yunlong Qin;
Zhanxin Zhu;
Jie Liu;
Shiren Sun

Publication type:

Literature Review

Cancer Metabolism as a Therapeutic Target: Finding the Right Target(s) in the Context of Tumor Heterogeneity, Evolution, and Metabolic Plasticity.

Published in:

Oncology (08909091), 2013, v. 27, n. 5, p. 1

By:

Avantaggiati, Maria Laura

Publication type:

Article

Cancer Metabolism as a Therapeutic Target: Metabolic Synthetic Lethality.

Published in:

Oncology (08909091), 2013, v. 27, n. 5, p. 1

By:

Bensaad, Karim;
Harris, Adrian L.

Publication type:

Article

The Obesity and Breast Cancer Connection: Advancing the Agenda.

Published in:

2011

By:

Chlebowski, Rowan T.

Publication type:

Opinion

Simulating lifestyle and medical interventions to prevent type-2 diabetes: an economic evaluation for Belgium.

Published in:

European Journal of Health Economics, 2022, v. 23, n. 2, p. 237, doi. 10.1007/s10198-021-01362-5

By:

Vandenberghe, Désirée

Publication type:

Article

Economic evaluation of the treatment of type 2 diabetes with insulin glargine based on the LAPTOP trial.

Published in:

European Journal of Health Economics, 2008, v. 9, n. 2, p. 165, doi. 10.1007/s10198-007-0057-2

By:

Janka, Hans Uwe;
Högy, Barbara

Publication type:

Article

The use of metformin in women with polycystic ovary syndrome: an updated review.

Published in:

Journal of Assisted Reproduction & Genetics, 2022, v. 39, n. 3, p. 573, doi. 10.1007/s10815-022-02429-9

By:

Notaro, Adriana Leal Griz;
Neto, Filipe Tenorio Lira

Publication type:

Article

Antidiabetic drug metformin affects the developmental competence of cleavage-stage embryos.

Published in:

Journal of Assisted Reproduction & Genetics, 2020, v. 37, n. 5, p. 1227, doi. 10.1007/s10815-020-01709-6

By:

Nayak, Guruprasad;
Salian, Sujith Raj;
Agarwal, Pooja;
Suresh Poojary, Pooja;
Rao, Arpitha;
Kumari, Sandhya;
Kalthur, Sneha Guruprasad;
Shreya, Ajjappla B.;
Mutalik, Srinivas;
Adiga, Satish Kumar;
Kalthur, Guruprasad

Publication type:

Article

Two-cell embryos are more sensitive than blastocysts to AMPK-dependent suppression of anabolism and stemness by commonly used fertility drugs, a diet supplement, and stress.

Published in:

Journal of Assisted Reproduction & Genetics, 2017, v. 34, n. 12, p. 1609, doi. 10.1007/s10815-017-1028-x

By:

Bolnick, Alan;
Abdulhasan, Mohammed;
Kilburn, Brian;
Xie, Yufen;
Howard, Mindie;
Andresen, Paul;
Shamir, Alexandra;
Dai, Jing;
Puscheck, Elizabeth;
Secor, Eric;
Rappolee, Daniel

Publication type:

Article

Commonly used fertility drugs, a diet supplement, and stress force AMPK-dependent block of stemness and development in cultured mammalian embryos.

Published in:

Journal of Assisted Reproduction & Genetics, 2016, v. 33, n. 8, p. 1027, doi. 10.1007/s10815-016-0735-z

By:

Bolnick, Alan;
Abdulhasan, Mohammed;
Kilburn, Brian;
Xie, Yufen;
Howard, Mindie;
Andresen, Paul;
Shamir, Alexandra;
Dai, Jing;
Puscheck, Elizabeth;
Rappolee, Daniel

Publication type:

Article

Protective effects of metformin on reproductive function in obese male rats induced by high-fat diet.

Published in:

Journal of Assisted Reproduction & Genetics, 2015, v. 32, n. 7, p. 1097, doi. 10.1007/s10815-015-0506-2

By:

Yan, Wen-jie;
Mu, Yang;
Yu, Nan;
Yi, Tai-lang;
Zhang, Yi;
Pang, Xiang-li;
Cheng, Dan;
Yang, Jing

Publication type:

Article

Metformin use in patients undergoing in vitro fertilization treatment: results of a worldwide web-based survey.

Published in:

Journal of Assisted Reproduction & Genetics, 2015, v. 32, n. 3, p. 401, doi. 10.1007/s10815-014-0414-x

By:

Christianson, Mindy;
Wu, Harold;
Zhao, Yulian;
Yemini, Matan;
Leong, Milton;
Shoham, Zeev

Publication type:

Article

Protein modification as oxidative stress marker in follicular fluid from women with polycystic ovary syndrome: the effect of inositol and metformin.

Published in:

Journal of Assisted Reproduction & Genetics, 2014, v. 31, n. 10, p. 1269, doi. 10.1007/s10815-014-0307-z

By:

Piomboni, P.;
Focarelli, R.;
Capaldo, A.;
Stendardi, A.;
Cappelli, V.;
Cianci, A.;
Marca, A.;
Luddi, A.;
Leo, V.

Publication type:

Article

The effects of metformin or orlistat on obese women with polycystic ovary syndrome: a prospective randomized open-label study.

Published in:

Journal of Assisted Reproduction & Genetics, 2011, v. 28, n. 7, p. 591, doi. 10.1007/s10815-011-9564-2

By:

Ghandi, Sedigheh;
Aflatoonian, Abbas;
Tabibnejad, Nasim;
Moghaddam, Mohammad

Publication type:

Article

Evaluating the equivalence of clomiphene citrate with and without metformin in ovulation induction in PCOS patients.

Published in:

Journal of Assisted Reproduction & Genetics, 2009, v. 26, n. 4, p. 165, doi. 10.1007/s10815-009-9304-z

By:

Siebert, T. I.;
Kruger, T. F.;
Lombard, Carl

Publication type:

Article

Physical exercise and metformin in gestational obesity and prevention on gestational diabetes mellitus: a systematic review.

Published in:

Brazilian Journal of Mother & Child Health (BJMCH) / Revista Brasileira de Saude Materno Infantil (RBSMI), 2020, v. 20, n. 1, p. 7, doi. 10.1590/1806-93042020000100002

By:

Baptistella do Nascimento, Iramar;
Fleig, Raquel;
Ramos de Souza, Matheus Leite;
Carl Silva, Jean

Publication type:

Article

Preditores de sucesso da metformina no tratamento do diabetes mellitus gestacional.

Published in:

Brazilian Journal of Mother & Child Health (BJMCH) / Revista Brasileira de Saude Materno Infantil (RBSMI), 2013, v. 13, n. 2, p. 129, doi. 10.1590/S1519-38292013000200006

By:

Silva, Jean Carl;
de Souza, Bárbara Vicente;
Silva, Mariana Ribeiro e

Publication type:

Article

Effects of metformin on lipopolysaccharide induced inflammation by activating fibroblast growth factor 21.

Published in:

Biotechnic & Histochemistry, 2022, v. 97, n. 1, p. 44, doi. 10.1080/10520295.2021.1894353

By:

Kar, Ezgi;
Alataş, Özkan;
Şahıntürk, Varol;
Öz, Semih

Publication type:

Article

Metformin alleviates experimental colitis in mice by up-regulating TGF-β signaling.

Published in:

Biotechnic & Histochemistry, 2021, v. 96, n. 2, p. 146, doi. 10.1080/10520295.2020.1776896

By:

Liu, Xuewei;
Sun, Zheng;
Wang, Haifeng

Publication type:

Article

Caralluma fimbriata and metformin protection of rat pancreas from high fat diet induced oxidative stress.

Published in:

Biotechnic & Histochemistry, 2018, v. 93, n. 3, p. 177, doi. 10.1080/10520295.2017.1406615

By:

Sudhakara, G;
Mallaiah, P;
Rajendran, R;
Saralakumari, D

Publication type:

Article

Pilot study of oral metformin in cancer-bearing cats.

Published in:

Veterinary & Comparative Oncology, 2017, v. 15, n. 2, p. 345, doi. 10.1111/vco.12169

By:

Wypij, J. M.

Publication type:

Article

Women's Health Endocrine Update.

Published in:

Journal of Women's Health (15409996), 2017, v. 26, n. 12, p. 1365, doi. 10.1089/jwh.2017.6434

By:

Kapoor, Ekta;
Faubion, Stephanie;
Hines, Stephanie;
Stuenkel, Cynthia A.

Publication type:

Article

Improving cardiovascular outcomes in type 2 diabetes.

Published in:

Practitioner, 2022, v. 266, n. 1858, p. 21

By:

Poole, Ruth

Publication type:

Article

Metformin and fibromyalgia pathophysiology: current insights and promising future therapeutic strategies.

Published in:

Molecular Biology Reports, 2024, v. 52, n. 1, p. 1, doi. 10.1007/s11033-024-10159-7

By:

AboTaleb, Hanin Abdulbaset;
Alghamdi, Badrah S.

Publication type:

Article

Coordination chemistry suggests that independently observed benefits of metformin and Zn<sup>2+</sup> against COVID-19 are not independent.

Published in:

BioMetals, 2024, v. 37, n. 4, p. 983, doi. 10.1007/s10534-024-00590-5

By:

Lockwood, Thomas D.

Publication type:

Article

Exploration of biguanido-oxovanadium complexes as potent and selective inhibitors of protein tyrosine phosphatases.

Published in:

BioMetals, 2012, v. 25, n. 3, p. 599, doi. 10.1007/s10534-012-9548-4

By:

Lu, Liping;
Gao, Xiaoli;
Zhu, Miaoli;
Wang, Sulian;
Wu, Qiong;
Xing, Shu;
Fu, Xueqi;
Liu, Zhiwei;
Guo, Maolin

Publication type:

Article

Autosomic dominant polycystic kidney disease and metformin: Old knowledge and new insights on retarding progression of chronic kidney disease.

Published in:

Medicinal Research Reviews, 2022, v. 42, n. 1, p. 629, doi. 10.1002/med.21850

By:

Casarella, Alessandro;
Nicotera, Ramona;
Zicarelli, Maria T.;
Urso, Alessandra;
Presta, Pierangela;
Deodato, Francesca;
Bolignano, Davide;
De Sarro, Giovambattista;
Andreucci, Michele;
Russo, Emilio;
Coppolino, Giuseppe

Publication type:

Article

Metformin treatment reduces the incidence of osteoporosis: a two-sample Mendelian randomized study.

Published in:

Osteoporosis International, 2024, v. 35, n. 6, p. 1089, doi. 10.1007/s00198-023-07013-0

By:

Cai, Yaotian;
Jun, Gao;
Zhuang, Xiaojie

Publication type:

Article

The effect of starting metformin on bone mineral density among women with type 2 diabetes in the Study of Women's Health Across the Nation (SWAN).

Published in:

Osteoporosis International, 2024, v. 35, n. 1, p. 189, doi. 10.1007/s00198-023-06915-3

By:

Solomon, Daniel H.;
Ruppert, Kristine;
Cauley, Jane A.;
Lian, Yinjuan;
Altwies, Hallie;
Shieh, Albert;
Burnett-Bowie, Sherri-Ann M.

Publication type:

Article

Long-term effects of lifestyle and metformin interventions in DPP on bone density.

Published in:

Osteoporosis International, 2021, v. 32, n. 11, p. 2279, doi. 10.1007/s00198-021-05989-1

By:

Schwartz, A. V.;
Pan, Q.;
Aroda, V. R.;
Crandall, J. P.;
Kriska, A.;
Piromalli, C.;
Wallia, A.;
Temprosa, M.;
Florez, H.

Publication type:

Article

Association between combined treatment with SGLT2 inhibitors and metformin for type 2 diabetes mellitus on fracture risk: a meta-analysis of randomized controlled trials.

Published in:

Osteoporosis International, 2020, v. 31, n. 12, p. 2313, doi. 10.1007/s00198-020-05590-y

By:

Qian, B-B.;
Chen, Q.;
Li, L.;
Yan, C-F.

Publication type:

Article

Metformin use and risk of fracture: a systematic review and meta-analysis of observational studies.

Published in:

Osteoporosis International, 2019, v. 30, n. 6, p. 1167, doi. 10.1007/s00198-019-04948-1

By:

Salari-Moghaddam, A.;
Sadeghi, O.;
Keshteli, A. H.;
Larijani, B.;
Esmaillzadeh, A.

Publication type:

Article

The effect of metformin versus placebo in combination with insulin analogues on bone mineral density and trabecular bone score in patients with type 2 diabetes mellitus: a randomized placebo-controlled trial.

Published in:

Osteoporosis International, 2018, v. 29, n. 11, p. 2517, doi. 10.1007/s00198-018-4637-z

By:

Nordklint, A. K.;
Almdal, T. P.;
Vestergaard, P.;
Lundby-Christensen, L.;
Boesgaard, T. W.;
Breum, L.;
Gade-Rasmussen, B.;
Sneppen, S. B.;
Gluud, C.;
Hemmingsen, B.;
Jensen, T.;
Krarup, T.;
Madsbad, S.;
Mathiesen, E. R.;
Perrild, H.;
Tarnow, L.;
Thorsteinsson, B.;
Vestergaard, H.;
Lund, S. S.;
Eiken, P.

Publication type:

Article

Real-world antidiabetic drug use and fracture risk in 12,277 patients with type 2 diabetes mellitus: a nested case-control study.

Published in:

Osteoporosis International, 2018, v. 29, n. 9, p. 2079, doi. 10.1007/s00198-018-4581-y

By:

Losada, E.;
Soldevila, B.;
Ali, M.S.;
Martínez-Laguna, D.;
Nogués, X.;
Puig-Domingo, M.;
Díez-Pérez, A.;
Mauricio, D.;
Prieto-Alhambra, D.

Publication type:

Article

Use of dipeptidyl peptidase-4 inhibitors and risk of bone fracture in patients with type 2 diabetes in Germany-A retrospective analysis of real-world data.

Published in:

Osteoporosis International, 2017, v. 28, n. 8, p. 2421, doi. 10.1007/s00198-017-4051-y

By:

Dombrowski, S.;
Kostev, K.;
Jacob, L.

Publication type:

Article

Fracture risk reduction with use of dipeptidyl peptidase-4 inhibitors: is there immortal time bias?

Published in:

2017

By:

Driessen, J.;
Knapen, L.;
Geusens, P.;
Bergh, J.

Publication type:

Letter

Risk of fractures and diabetes medications: a nationwide cohort study.

Published in:

Osteoporosis International, 2016, v. 27, n. 9, p. 2709, doi. 10.1007/s00198-016-3595-6

By:

Choi, H.;
Park, C.;
Lee, Y.-K.;
Ha, Y.-C.;
Jang, S.;
Shin, C.

Publication type:

Article

Fatal metformin overdose: case report and postmortem biochemistry contribution.

Published in:

2014

By:

Bonsignore, Alessandro;
Pozzi, Fulvia;
Fraternali Orcioni, Giulio;
Ventura, Francesco;
Palmiere, Cristian

Publication type:

Report

Metformin prevents p-tau and amyloid plaque deposition and memory impairment in diabetic mice.

Published in:

Experimental Brain Research, 2021, v. 239, n. 9, p. 2821, doi. 10.1007/s00221-021-06176-8

By:

Oliveira, Wilma Helena;
Braga, Clarissa Figueiredo;
Lós, Deniele Bezerra;
Araújo, Shyrlene Meiry Rocha;
França, MariaEduarda Rocha;
Duarte-Silva, Eduardo;
Rodrigues, Gabriel Barros;
Rocha, Sura Wanessa Santos;
Peixoto, Christina Alves

Publication type:

Article

Metformin improves depressive-like symptoms in mice via inhibition of peripheral and central NF-κB-NLRP3 inflammation activation.

Published in:

Experimental Brain Research, 2020, v. 238, n. 11, p. 2549, doi. 10.1007/s00221-020-05911-x

By:

Du, Ren-Wei;
Bu, Wen-Guang

Publication type:

Article