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Loss of cholinergic innervation differentially affects eNOS-mediated blood flow, drainage of Aβ and cerebral amyloid angiopathy in the cortex and hippocampus of adult mice.
- Published in:
- Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-020-01108-z
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- Publication type:
- Article
Editorial: The Neurovascular Unit as a Potential Biomarker and Therapeutic Target in Cerebrovascular Disease.
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- 2022
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- Publication type:
- Editorial
Endothelial-Derived Extracellular Vesicles Induce Cerebrovascular Dysfunction in Inflammation.
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- Pharmaceutics, 2021, v. 13, n. 9, p. 1525, doi. 10.3390/pharmaceutics13091525
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- Publication type:
- Article
Prenatal high-fat diet alters the cerebrovasculature and clearance of β-amyloid in adult offspring.
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- Journal of Pathology, 2015, v. 235, n. 4, p. 619, doi. 10.1002/path.4468
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- Publication type:
- Article
Clearance of interstitial fluid (ISF) and CSF (CLIC) group‐part of Vascular Professional Interest Area (PIA), updates in 2022‐2023. Cerebrovascular disease and the failure of elimination of Amyloid‐β from the brain and retina with age and Alzheimer's disease: Opportunities for therapy
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 2, p. 1421, doi. 10.1002/alz.13512
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- Publication type:
- Article
P3‐006: THE CASE FOR CHOLINESTERASE INHIBITION TO MODIFY NEURODEGENERATIVE DISEASES THROUGH THE INTRAMURAL PERIARTERIAL DRAINAGE OF THE CNS (IPAD).
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P926, doi. 10.1016/j.jalz.2019.06.3032
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- Publication type:
- Article
F1‐03‐01: CONVECTIVE INFLUX/GLYMPHATIC SYSTEM: TRACERS INJECTED INTO THE CSF ENTER AND LEAVE THE BRAIN ALONG SEPARATE PERIARTERIAL BASEMENT MEMBRANE PATHWAYS.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P204, doi. 10.1016/j.jalz.2018.06.2311
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- Publication type:
- Article
A Review of the Impact of Maternal Obesity on the Cognitive Function and Mental Health of the Offspring.
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- International Journal of Molecular Sciences, 2017, v. 18, n. 5, p. 1093, doi. 10.3390/ijms18051093
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- Publication type:
- Article
Cerebrospinal fluid dynamics modulation by diet and cytokines in rats.
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- Fluids & Barriers of the CNS, 2020, v. 17, n. 1, p. 1, doi. 10.1186/s12987-020-0168-z
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- Publication type:
- Article
The cerebrovascular basement membrane: role in the clearance of β-amyloid and cerebral amyloid angiopathy.
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- Frontiers in Aging Neuroscience, 2014, v. 6, p. 1, doi. 10.3389/fnagi.2014.00251
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- Publication type:
- Article
Cyclohexanehexol inhibitors of Aβ aggregation prevent and reverse Alzheimer phenotype in a mouse model.
- Published in:
- Nature Medicine, 2006, v. 12, n. 7, p. 801, doi. 10.1038/nm1423
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- Publication type:
- Article
BETA-AMYLOID PATHOLOGY IS INCREASED IN TG2576 MICE BORN TO MOTHERS FED A HIGH-FAT DIET.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P738, doi. 10.1016/j.jalz.2016.06.1541
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- Publication type:
- Article
Perivascular clearance of amyloid-beta.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 7, p. P114, doi. 10.1016/j.jalz.2015.07.004
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- Publication type:
- Article
Aβ uptake by non-plaque associated microglia
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- 2012
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- Publication type:
- Abstract
Processes underlying the vascular pathophysiology associated with Aβ immunization in Alzheimer's disease
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- 2010
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- Publication type:
- Abstract
The effect of scyllo-inositol derivatives on β-amyloid peptide aggregation
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- 2009
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- Publication type:
- Abstract
Selective targeting of perivascular macrophages for β-amyloid clearance in cerebral amyloid angiopathy
- Published in:
- 2009
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- Publication type:
- Abstract
P2-048: Up-regulation of IGF-II/M6P receptor and other endosomal-lysosomal markers in cells surviving toxicity
- Published in:
- 2006
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- Publication type:
- Abstract
P2-048: Up-regulation of IGF-II/M6P receptor and other endosomal-lysosomal markers in cells surviving toxicity
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- 2006
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- Publication type:
- Abstract
Increased Aβ pathology in aged Tg2576 mice born to mothers fed a high fat diet.
- Published in:
- Scientific Reports, 2016, p. 21981, doi. 10.1038/srep21981
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- Publication type:
- Article
A Simulation Model of Periarterial Clearance of Amyloid-β from the Brain.
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- Frontiers in Aging Neuroscience, 2016, p. 1, doi. 10.3389/fnagi.2016.00018
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- Publication type:
- Article
Disruption of Arterial Perivascular Drainage of Amyloid-β from the Brains of Mice Expressing the Human APOE ϵ4 Allele.
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- PLoS ONE, 2012, v. 7, n. 7, p. 1, doi. 10.1371/journal.pone.0041636
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- Publication type:
- Article
MK886 Reduces Cerebral Amyloid Angiopathy Severity in TgCRND8 Mice.
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- Neurodegenerative Diseases, 2013, v. 13, n. 1, p. 17, doi. 10.1159/000351096
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- Publication type:
- Article
Current Understanding of the Anatomy, Physiology, and Magnetic Resonance Imaging of Neurofluids: Update From the 2022 "ISMRM Imaging Neurofluids Study group" Workshop in Rome.
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- Journal of Magnetic Resonance Imaging, 2024, v. 59, n. 2, p. spcone, doi. 10.1002/jmri.28759
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- Publication type:
- Article
Current Understanding of the Anatomy, Physiology, and Magnetic Resonance Imaging of Neurofluids: Update From the 2022 "ISMRM Imaging Neurofluids Study group" Workshop in Rome.
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- Journal of Magnetic Resonance Imaging, 2024, v. 59, n. 2, p. 431, doi. 10.1002/jmri.28759
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- Publication type:
- Article
The evolutionarily conserved long non‐coding RNA LINC00261 drives neuroendocrine prostate cancer proliferation and metastasis via distinct nuclear and cytoplasmic mechanisms.
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- Molecular Oncology, 2021, v. 15, n. 7, p. 1921, doi. 10.1002/1878-0261.12954
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- Publication type:
- Article
Single Transmembrane Domain Insulin-Like Growth Factor- II/Mannose-6-Phosphate Receptor Regulates Central Cholinergic Function by Activating a G-Protein-Sensitive, Protein Kinase C-Dependent Pathway.
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- Journal of Neuroscience, 2006, v. 26, n. 2, p. 585, doi. 10.1523/JNEUROSCI.2730-05.2006
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- Publication type:
- Article
α-Dystrobrevin knockout mice have increased motivation for appetitive reward and altered brain cannabinoid receptor 1 expression.
- Published in:
- Acta Neuropathologica Communications, 2022, v. 10, n. 1, p. 1, doi. 10.1186/s40478-022-01434-4
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- Publication type:
- Article
α-Dystrobrevin knockout mice have increased motivation for appetitive reward and altered brain cannabinoid receptor 1 expression.
- Published in:
- Acta Neuropathologica Communications, 2022, v. 10, n. 1, p. 1, doi. 10.1186/s40478-022-01434-4
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- Publication type:
- Article
3D Reconstruction of the Neurovascular Unit Reveals Differential Loss of Cholinergic Innervation in the Cortex and Hippocampus of the Adult Mouse Brain.
- Published in:
- Frontiers in Aging Neuroscience, 2019, p. 1, doi. 10.3389/fnagi.2019.00172
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- Publication type:
- Article
Amyloid-β-dependent compromise of microvascular structure and function in a model of Alzheimer’s disease.
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- Brain: A Journal of Neurology, 2012, v. 135, n. 10, p. 3039, doi. 10.1093/brain/aws243
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- Publication type:
- Article
Insulin-like growth factor-II/mannose-6-phosphate receptor: Widespread distribution in neurons of the central nervous system including those expressing cholinergic phenotype.
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- Journal of Comparative Neurology, 2003, v. 458, n. 2, p. 113, doi. 10.1002/cne.10578
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- Publication type:
- Article
White Matter Changes in Dementia: Role of Impaired Drainage of Interstitial Fluid.
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- Brain Pathology, 2015, v. 25, n. 1, p. 63, doi. 10.1111/bpa.12218
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- Publication type:
- Article
Failure of Perivascular Drainage of β-amyloid in Cerebral Amyloid Angiopathy.
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- Brain Pathology, 2014, v. 24, n. 4, p. 396, doi. 10.1111/bpa.12159
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- Publication type:
- Article
Small molecule inhibitors of Aβ-aggregation and neurotoxicity.
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- Drug Development Research, 2009, v. 70, n. 2, p. 111, doi. 10.1002/ddr.20290
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- Publication type:
- Article
S1P Is Associated with Protection in Human and Experimental Cerebral Malaria.
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- Molecular Medicine, 2011, v. 17, n. 7/8, p. 717, doi. 10.2119/molmed.2010.00214
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- Publication type:
- Article
Convective influx/glymphatic system: tracers injected into the CSF enter and leave the brain along separate periarterial basement membrane pathways.
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- Acta Neuropathologica, 2018, v. 136, n. 1, p. 139, doi. 10.1007/s00401-018-1862-7
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- Publication type:
- Article
Vascular basement membranes as pathways for the passage of fluid into and out of the brain.
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- Acta Neuropathologica, 2016, v. 131, n. 5, p. 725, doi. 10.1007/s00401-016-1555-z
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- Publication type:
- Article
Does the difference between PART and Alzheimer's disease lie in the age-related changes in cerebral arteries that trigger the accumulation of Aβ and propagation of tau?
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- 2015
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- Publication type:
- Letter
Amyloid and tau in the brain in sporadic Alzheimer's disease: defining the chicken and the egg.
- Published in:
- 2014
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- Publication type:
- Letter
Perivascular drainage of solutes is impaired in the ageing mouse brain and in the presence of cerebral amyloid angiopathy.
- Published in:
- Acta Neuropathologica, 2011, v. 121, n. 4, p. 431, doi. 10.1007/s00401-011-0801-7
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- Publication type:
- Article
Small molecule β-amyloid inhibitors that stabilize protofibrillar structures in vitro improve cognition and pathology in a mouse model of Alzheimer’s disease.
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- European Journal of Neuroscience, 2010, v. 31, n. 2, p. 203, doi. 10.1111/j.1460-9568.2009.07052.x
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- Publication type:
- Article
Pre- and Post-natal High Fat Feeding Differentially Affects the Structure and Integrity of the Neurovascular Unit of 16-Month Old Male and Female Mice.
- Published in:
- Frontiers in Neuroscience, 2019, p. 1, doi. 10.3389/fnins.2019.01045
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- Publication type:
- Article
Small vessels, dementia and chronic diseases - molecular mechanisms and pathophysiology.
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- Clinical Science, 2018, v. 132, n. 8, p. 851, doi. 10.1042/CS20171620
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- Publication type:
- Article
The role of perivascular innervation and neurally mediated vasoreactivity in the pathophysiology of Alzheimer's disease.
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- Clinical Science, 2017, v. 131, n. 12, p. 1207, doi. 10.1042/CS20160769
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- Publication type:
- Article
Regional differences in the morphological and functional effects of aging on cerebral basement membranes and perivascular drainage of amyloid-β from the mouse brain.
- Published in:
- Aging Cell, 2013, v. 12, n. 2, p. 224, doi. 10.1111/acel.12045
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- Publication type:
- Article
Phosphodiesterase III inhibitor promotes drainage of cerebrovascular β-amyloid.
- Published in:
- Annals of Clinical & Translational Neurology, 2014, v. 1, n. 8, p. 519, doi. 10.1002/acn3.79
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- Publication type:
- Article
Both Maternal High-Fat and Post-Weaning High-Carbohydrate Diets Increase Rates of Spontaneous Hepatocellular Carcinoma in Aged-Mouse Offspring.
- Published in:
- Nutrients, 2024, v. 16, n. 16, p. 2805, doi. 10.3390/nu16162805
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- Publication type:
- Article
Appetitive Motivation and Associated Neurobiology Change Differentially across the Life Course of Mouse Offspring Exposed to Peri- and Postnatal High Fat Feeding.
- Published in:
- Nutrients, 2022, v. 14, n. 23, p. 5161, doi. 10.3390/nu14235161
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- Publication type:
- Article