We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Post-Prandial Cognitive and Blood Pressure Effects of a DHA-Rich Omega-3 Powder in Middle-Aged Males: A Pilot Study.
- Authors
Pipingas, Andrew; Reddan, Jeffery Michael; Gauci, Sarah; Young, Lauren M.; Kennedy, Greg; Rowsell, Renee; King, Rebecca; Spiteri, Sam; Minihane, Anne Marie; Scholey, Andrew
- Abstract
The use of omega-3 polyunsaturated fatty acid (ω-3 PUFA) supplements is increasingly common among middle-aged and older adults. Users of ω-3 PUFA supplements often report using such supplements to support cognitive health, despite mixed findings reported within the ω-3 PUFA literature. To date, very few studies have explored cognitive effects in distinctly middle-aged (40 to 60 years) adults, and none have examined the acute effects (in the hours following a single dose) on cognitive performance. The current study evaluated whether a single dose of ω-3 PUFA (4020 mg docosahexaenoic acid and 720 mg eicosapentaenoic acid) influences cognitive performance and cardiovascular function in middle-aged males. Cognitive performance and cardiovascular function were assessed before and 3.5–4 h after consumption of a high dose of ω-3 PUFA (DHA EPA) or placebo, incorporated into a standardized meal (i.e., single serve of Greek yogurt). In this study of middle-aged males, no significant differential treatment effects were observed for cognitive performance. However, a significant reduction in aortic systolic blood pressure (pre-dose to post-dose) was apparent following consumption of the ω-3 PUFA (DHA EPA) treatment (mean difference = −4.11 mmHg, p = 0.004) but not placebo (mean difference = −1.39 mmHg, p = 0.122). Future replication in a sample comprising females, as well as patients with hypertension, is merited.
- Subjects
BLOOD pressure; DOCOSAHEXAENOIC acid; UNSATURATED fatty acids; YOGURT; MEN'S health; CARDIOVASCULAR system physiology; FOOD consumption; SYSTOLIC blood pressure; COGNITION; DIETARY supplements; EICOSAPENTAENOIC acid; RANDOMIZED controlled trials; PLACEBOS; PRE-tests & post-tests; BLIND experiment; DESCRIPTIVE statistics; RESEARCH funding; DOSE-effect relationship in pharmacology; CROSSOVER trials; STATISTICAL sampling; AORTA; POWDERS; MEALS
- Publication
Nutrients, 2023, Vol 15, Issue 9, p2198
- ISSN
2072-6643
- Publication type
Academic Journal
- DOI
10.3390/nu15092198