Works matching DE "UBIQUITINATION"

Results: 3898

Brassinosteroid Signaling Dynamics: Ubiquitination-Dependent Regulation of Core Signaling Components.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 10, p. 4502, doi. 10.3390/ijms26104502

By:

Qiu, Riguang;
Zhou, Yan;
Mao, Juan

Publication type:

Article

Structural basis for the RING-catalyzed synthesis of K63-linked ubiquitin chains.

Published in:

Nature Structural & Molecular Biology, 2015, v. 22, n. 8, p. 597, doi. 10.1038/nsmb.3052

By:

Branigan, Emma;
Plechanovová, Anna;
Jaffray, Ellis G;
Naismith, James H;
Hay, Ronald T

Publication type:

Article

K63 polyubiquitination is a new modulator of the oxidative stress response.

Published in:

Nature Structural & Molecular Biology, 2015, v. 22, n. 2, p. 116, doi. 10.1038/nsmb.2955

By:

Silva, Gustavo M;
Finley, Daniel;
Vogel, Christine

Publication type:

Article

Histone H2A monoubiquitination promotes histone H3 methylation in Polycomb repression.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 6, p. 569, doi. 10.1038/nsmb.2833

By:

Kalb, Reinhard;
Latwiel, Sebastian;
Baymaz, H Irem;
Jansen, Pascal W T C;
Müller, Christoph W;
Vermeulen, Michiel;
Müller, Jürg

Publication type:

Article

Plant ubiquitin ligases as signaling hubs.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 4, p. 293, doi. 10.1038/nsmb.2804

By:

Shabek, Nitzan;
Zheng, Ning

Publication type:

Article

The JAMM in the proteasome.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 4, p. 346, doi. 10.1038/nsmb.2800

By:

Wauer, Tobias;
Komander, David

Publication type:

Article

Ubiquitin sets the timer: impacts on aging and longevity.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 4, p. 290, doi. 10.1038/nsmb.2806

By:

Kevei, Éva;
Hoppe, Thorsten

Publication type:

Article

New insights into ubiquitin E3 ligase mechanism.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 4, p. 301, doi. 10.1038/nsmb.2780

By:

Berndsen, Christopher E;
Wolberger, Cynthia

Publication type:

Article

Dynamic regulation of macroautophagy by distinctive ubiquitin-like proteins.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 4, p. 336, doi. 10.1038/nsmb.2787

By:

Klionsky, Daniel J;
Schulman, Brenda A

Publication type:

Article

Two-way communications between ubiquitin-like modifiers and DNA.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 4, p. 317, doi. 10.1038/nsmb.2805

By:

Ulrich, Helle D

Publication type:

Article

Ubiquitin in inflammation: the right linkage makes all the difference.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 4, p. 297, doi. 10.1038/nsmb.2808

By:

Corn, Jacob E;
Vucic, Domagoj

Publication type:

Article

Cleaning up in the endoplasmic reticulum: ubiquitin in charge.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 4, p. 325, doi. 10.1038/nsmb.2793

By:

Christianson, John C;
Ye, Yihong

Publication type:

Article

Essential modifications.

Published in:: Nature Structural & Molecular Biology, 2014, v. 21, n. 4, p. 289, doi. 10.1038/nsmb.2811
Publication type:: Article

Lysine-targeting specificity in ubiquitin and ubiquitin-like modification pathways.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 4, p. 308, doi. 10.1038/nsmb.2792

By:

Mattiroli, Francesca;
Sixma, Titia K

Publication type:

Article

Centromeric histone H2B monoubiquitination promotes noncoding transcription and chromatin integrity.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 3, p. 236, doi. 10.1038/nsmb.2776

By:

Sadeghi, Laia;
Siggens, Lee;
Svensson, J Peter;
Ekwall, Karl

Publication type:

Article

JMJD1C demethylates MDC1 to regulate the RNF8 and BRCA1-mediated chromatin response to DNA breaks.

Published in:

Nature Structural & Molecular Biology, 2013, v. 20, n. 12, p. 1425, doi. 10.1038/nsmb.2702

By:

Watanabe, Sugiko;
Watanabe, Kenji;
Akimov, Vyacheslav;
Bartkova, Jirina;
Blagoev, Blagoy;
Lukas, Jiri;
Bartek, Jiri

Publication type:

Article

Essentiality of a non-RING element in priming donor ubiquitin for catalysis by a monomeric E3.

Published in:

Nature Structural & Molecular Biology, 2013, v. 20, n. 8, p. 982, doi. 10.1038/nsmb.2621

By:

Dou, Hao;
Buetow, Lori;
Sibbet, Gary J;
Cameron, Kenneth;
Huang, Danny T

Publication type:

Article

EMI1, a three-in-one ubiquitylation inhibitor.

Published in:

Nature Structural & Molecular Biology, 2013, v. 20, n. 7, p. 773, doi. 10.1038/nsmb.2626

By:

Yamano, Hiroyuki

Publication type:

Article

Structure of a ubiquitin-loaded HECT ligase reveals the molecular basis for catalytic priming.

Published in:

Nature Structural & Molecular Biology, 2013, v. 20, n. 6, p. 696, doi. 10.1038/nsmb.2566

By:

Maspero, Elena;
Valentini, Eleonora;
Mari, Sara;
Cecatiello, Valentina;
Soffientini, Paolo;
Pasqualato, Sebastiano;
Polo, Simona

Publication type:

Article

Sequential primed kinases create a damage-responsive phosphodegron on Eco1.

Published in:

Nature Structural & Molecular Biology, 2013, v. 20, n. 2, p. 194, doi. 10.1038/nsmb.2478

By:

Lyons, Nicholas A;
Fonslow, Bryan R;
Diedrich, Jolene K;
Yates, John R;
Morgan, David O

Publication type:

Article

Development of ADPribosyl Ubiquitin Analogues to Study Enzymes Involved in Legionella Infection.

Published in:

Chemistry - A European Journal, 2021, v. 27, n. 7, p. 2506, doi. 10.1002/chem.202004590

By:

Kim, Robbert Q.;
Misra, Mohit;
Gonzalez, Alexis;
Tomašković, Ines;
Shin, Donghyuk;
Schindelin, Hermann;
Filippov, Dmitri V.;
Ovaa, Huib;
Đikić, Ivan;
Heden van Noort, Gerbrand J.

Publication type:

Article

A Buchwald–Hartwig Protocol to Enable Rapid Linker Exploration of Cereblon E3‐Ligase PROTACs**.

Published in:

Chemistry - A European Journal, 2020, v. 26, n. 70, p. 16818, doi. 10.1002/chem.202003137

By:

Hayhow, Thomas G.;
Borrows, Rachel E. A.;
Diène, Coura R.;
Fairley, Gary;
Fallan, Charlene;
Fillery, Shaun M.;
Scott, James S.;
Watson, David W.

Publication type:

Article

Fluorescently Labelled ATP Analogues for Direct Monitoring of Ubiquitin Activation.

Published in:

Chemistry - A European Journal, 2020, v. 26, n. 28, p. 6279, doi. 10.1002/chem.202001091

By:

Hammler, Daniel;
Stuber, Katrin;
Offensperger, Fabian;
Scheffner, Martin;
Zumbusch, Andreas;
Marx, Andreas

Publication type:

Article

Modifying the Vicinity of the Isopeptide Bond To Reveal Differential Behavior of Ubiquitin Chains with Interacting Proteins: Organic Chemistry Applied to Synthetic Proteins.

Published in:

Angewandte Chemie, 2013, v. 125, n. 42, p. 11355, doi. 10.1002/ange.201306118

By:

Haj ‐ Yahya, Najat;
Haj ‐ Yahya, Mahmood;
Castañeda, Carlos A.;
Spasser, Liat;
Hemantha, Hosahalli P.;
Jbara, Muhammad;
Penner, Marlin;
Ciechanover, Aaron;
Fushman, David;
Brik, Ashraf

Publication type:

Article

Convergent Chemical Synthesis of Histone H2B Protein for the Site-Specific Ubiquitination at Lys34.

Published in:

Angewandte Chemie, 2013, v. 125, n. 31, p. 8217, doi. 10.1002/ange.201303844

By:

Siman, Peter;
Karthikeyan, Subramanian Vedhanarayanan;
Nikolov, Miroslav;
Fischle, Wolfgang;
Brik, Ashraf

Publication type:

Article

TRIM11 modulates sepsis progression by promoting HOXB9 ubiquitination and inducing the NF-κB signaling pathway.

Published in:

Molecular Biology Reports, 2025, v. 52, n. 1, p. 1, doi. 10.1007/s11033-024-10212-5

By:

Gan, Jiaqi;
Zhang, Wei;
Pan, Fei;
Qiu, Zhiyun;
Chen, Xiaobing

Publication type:

Article

The Bre1/Rad6 machinery: writing the central histone ubiquitin mark on H2B and beyond.

Published in:

Chromosome Research, 2020, v. 28, n. 3/4, p. 247, doi. 10.1007/s10577-020-09640-3

By:

Deng, Zhi-Heng;
Ai, Hua-Song;
Lu, Cheng-Piao;
Li, Jia-Bin

Publication type:

Article

Antiproliferative activity exerted by tricyclohexylphosphanegold(I) n-mercaptobenzoate against MCF-7 and A2780 cell lines: the role of p53 signaling pathways.

Published in:

BioMetals, 2021, v. 34, n. 1, p. 141, doi. 10.1007/s10534-020-00269-7

By:

Ang, Kok Pian;
Chan, Pit Foong;
Hamid, Roslida Abd

Publication type:

Article

Hepatic and adipocyte cells respond differentially to iron overload, hypoxic and inflammatory challenge.

Published in:

BioMetals, 2012, v. 25, n. 4, p. 749, doi. 10.1007/s10534-012-9543-9

By:

Andrews, M.;
Arredondo, M.

Publication type:

Article

Triad3A attenuates pathological cardiac hypertrophy involving the augmentation of ubiquitination-mediated degradation of TLR4 and TLR9.

Published in:

Basic Research in Cardiology, 2020, v. 115, n. 2, p. 1, doi. 10.1007/s00395-020-0779-1

By:

Lu, Xia;
He, Yijie;
Tang, Chao;
Wang, Xiaoyang;
Que, Linli;
Zhu, Guoqing;
Liu, Li;
Ha, Tuanzhu;
Chen, Qi;
Li, Chuanfu;
Xu, Yong;
Li, Jiantao;
Li, Yuehua

Publication type:

Article

The post-translational modification of Fascin: impact on cell biology and its associations with inhibiting tumor metastasis.

Published in:

Amino Acids, 2022, v. 54, n. 12, p. 1541, doi. 10.1007/s00726-022-03193-x

By:

Nan-Li;
Zhang, Zhi-Da;
Li, Rong-Rong;
Chen, Jia-You;
Huang, Hong-Xin;
Cheng, Yin-Wei;
Xu, Li-Yan;
Li, En-Min

Publication type:

Article

Post-translational modifications in tumor-associated carbonic anhydrases.

Published in:

Amino Acids, 2022, v. 54, n. 4, p. 543, doi. 10.1007/s00726-021-03063-y

By:

Di Fiore, Anna;
Supuran, Claudiu T.;
Scaloni, Andrea;
De Simone, Giuseppina

Publication type:

Article

Enteral glutamine infusion modulates ubiquitination of heat shock proteins, Grp-75 and Apg-2, in the human duodenal mucosa.

Published in:

Amino Acids, 2014, v. 46, n. 4, p. 1059, doi. 10.1007/s00726-014-1670-x

By:

Bertrand, Julien;
Goichon, Alexis;
Chan, Philippe;
Azhar, Saida;
Lecleire, Stéphane;
Donnadieu, Nathalie;
Vaudry, David;
Cailleux, Anne-Françoise;
Déchelotte, Pierre;
Coëffier, Moïse

Publication type:

Article

RUBI: rapid proteomic-scale prediction of lysine ubiquitination and factors influencing predictor performance.

Published in:

Amino Acids, 2014, v. 46, n. 4, p. 853, doi. 10.1007/s00726-013-1645-3

By:

Walsh, Ian;
Domenico, Tomás;
Tosatto, Silvio

Publication type:

Article

Prediction of lysine ubiquitination with mRMR feature selection and analysis.

Published in:

Amino Acids, 2012, v. 42, n. 4, p. 1387, doi. 10.1007/s00726-011-0835-0

By:

Cai, Yudong;
Huang, Tao;
Hu, Lele;
Shi, Xiaohe;
Xie, Lu;
Li, Yixue

Publication type:

Article

Aurora A binds to the transactivation domain of c-Myc and recognizes the phosphorylated N-terminal degron motif.

Published in:

Biochemical Journal, 2025, v. 482, n. 8, p. 369, doi. 10.1042/BCJ20240726

By:

Nidhi Joshi;
Dunleavy, Katie M.;
Beel, Kaitlin M.;
Engel, Tiffany A.;
Thompson, Andrew R.;
John, Felix L.;
Thomas, David D.;
Levinson, Nicholas M.

Publication type:

Article

CARD14 signalosome formation is associated with its endosomal relocation and mTORC1-induced keratinocyte proliferation.

Published in:

Biochemical Journal, 2024, v. 481, n. 18, p. 1143, doi. 10.1042/BCJ20240058

By:

O’Sullivan, Paul A.;
Aidarova, Aigerim;
Afonina, Inna S.;
Manils, Joan;
Thurston, Teresa L. M.;
Instrell, Rachael;
Howell, Michael;
Boeing, Stefan;
Ranawana, Sashini;
Herpels, Melanie B.;
Chetian, Riwia;
Bassa, Matilda;
Flynn, Helen;
Frith, David;
Snijders, Ambrosius P.;
Howes, Ashleigh;
Beyaert, Rudi;
Bowcock, Anne M.;
Ley, Steven C.

Publication type:

Article

Ring finger protein 138 inhibits transcription factor C/EBPα protein turnover leading to differentiation arrest in acute myeloid leukemia.

Published in:

Biochemical Journal, 2024, v. 481, n. 10, p. 653, doi. 10.1042/BCJ20240027

By:

Singh, Anil Kumar;
Upadhyay, Vishal;
Sethi, Arppita;
Chowdhury, Sangita;
Mishra, Shivkant;
Verma, Shailendra Prasad;
Bhatt, Madan Lal Brahma;
Trivedi, Arun Kumar

Publication type:

Article

Dynamic interactions between SPX proteins, the ubiquitination machinery, and signalling molecules for stress adaptation at a whole-plant level.

Published in:

Biochemical Journal, 2024, v. 481, n. 5, p. 363, doi. 10.1042/BCJ20230163

By:

Collins, Emma;
Huixia Shou;
Chuanzao Mao;
Whelan, James;
Jost, Ricarda

Publication type:

Article

Catalysis of non-canonical protein ubiquitylation by the ARIH1 ubiquitin ligase.

Published in:

Biochemical Journal, 2023, v. 480, n. 22, p. 1817, doi. 10.1042/BCJ20230373

By:

Purser, Nicholas;
Tripathi-Giesgen, Ishita;
Li, Jerry;
Scott, Daniel C.;
Horn-Ghetko, Daniel;
Baek, Kheewoong;
Schulman, Brenda A.;
Alpi, Arno F.;
Kleiger, Gary

Publication type:

Article

UBE2A/B is the trans-acting factor mediating mechanotransduction and contact inhibition.

Published in:

Biochemical Journal, 2023, v. 480, n. 20, p. 1659, doi. 10.1042/BCJ20230208

By:

Mingwei Feng;
Jiale Wang;
Kangjing Li;
Fumihiko Nakamura

Publication type:

Article

ERK1/2 inhibitors act as monovalent degraders inducing ubiquitylation and proteasome-dependent turnover of ERK2, but not ERK1.

Published in:

Biochemical Journal, 2023, v. 480, n. 9, p. 587, doi. 10.1042/BCJ20220598

By:

Balmanno, Kathryn;
Kidger, Andrew M.;
Byrne, Dominic P.;
Sale, Matthew J.;
Nassman, Nejma;
Eyers, Patrick A.;
Cook, Simon J.

Publication type:

Article

Overexpression of ARM repeat/U-box containing E3 ligase, PUB2 positively regulates growth and oxidative stress response in Arabidopsis.

Published in:

Biochemical Journal, 2023, v. 480, n. 9, p. 555, doi. 10.1042/BCJ20230026

By:

Saini, Lokesh K.;
Sharma, Manisha;
Ravi, Barkha;
Ghosh, Soma;
Pahuja, Sonam;
Singh, Nidhi;
Pandey, Girdhar K.

Publication type:

Article

A Plasmodium falciparum ubiquitin-specific protease (PfUSP) is essential for parasite survival and its disruption enhances artemisinin efficacy.

Published in:

Biochemical Journal, 2023, v. 480, n. 1, p. 25, doi. 10.1042/BCJ20220429

By:

Arora, Priya;
Narwal, Monika;
Thakur, Vandana;
Mukhtar, Osama;
Malhotra, Pawan;
Mohmmed, Asif

Publication type:

Article

Identification of ester-linked ubiquitylation sites during TLR7 signalling increases the number of inter-ubiquitin linkages from 8 to 12.

Published in:

Biochemical Journal, 2022, v. 479, n. 23, p. 2419, doi. 10.1042/BCJ20220510

By:

McCrory, Elisha H.;
Akimov, Vyacheslav;
Cohen, Philip;
Blagoev, Blagoy

Publication type:

Article

Co-ordinated control of the ADP-heptose/ALPK1 signalling network by the E3 ligases TRAF6, TRAF2/c-IAP1 and LUBAC.

Published in:

Biochemical Journal, 2022, v. 479, n. 20, p. 2195, doi. 10.1042/BCJ20220401

By:

Snelling, Tom;
Shpiro, Natalia;
Gourlay, Robert;
Lamoliatte, Frederic;
Cohen, Philip

Publication type:

Article

Deubiquitinases in cell death and inflammation.

Published in:

Biochemical Journal, 2022, v. 479, n. 10, p. 1103, doi. 10.1042/BCJ20210735

By:

Newton, Kim;
Gitlin, Alexander D.

Publication type:

Article

RIP1 post-translational modifications.

Published in:

Biochemical Journal, 2022, v. 479, n. 9, p. 929, doi. 10.1042/BCJ20210725

By:

Varfolomeev, Eugene;
Vucic, Domagoj

Publication type:

Article

Reconstitution of the DTX3L-PARP9 complex reveals determinants for high-affinity heterodimerization and multimeric assembly.

Published in:

Biochemical Journal, 2022, v. 479, n. 3, p. 289, doi. 10.1042/BCJ20210722

By:

Ashok, Yashwanth;
Vela-Rodríguez, Carlos;
Chunsong Yang;
Alanen, Heli I.;
Fan Liu;
Paschal, Bryce M.;
Lehtiö, Lari

Publication type:

Article

Molecular mechanisms of mammalian autophagy.

Published in:

Biochemical Journal, 2021, v. 478, n. 18, p. 3395, doi. 10.1042/BCJ20210314

By:

Trelford, Charles B.;
Di Guglielmo, Gianni M.

Publication type:

Article