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Title

Recent Research and Application Prospect of Functional Oligosaccharides on Intestinal Disease Treatment.

Authors

Xu, Tong; Sun, Ruijie; Zhang, Yuchen; Zhang, Chen; Wang, Yujing; Wang, Zhuo A.; Du, Yuguang

Abstract

The intestinal tract is an essential digestive organ of the human body, and damage to the intestinal barrier will lead to various diseases. Functional oligosaccharides are carbohydrates with a low degree of polymerization and exhibit beneficial effects on human intestinal health. Laboratory experiments and clinical studies indicate that functional oligosaccharides repair the damaged intestinal tract and maintain intestinal homeostasis by regulating intestinal barrier function, immune response, and intestinal microbial composition. Functional oligosaccharides treat intestinal disease such as inflammatory bowel disease (IBD) and colorectal cancer (CRC) and have excellent prospects for therapeutic application. Here, we present an overview of the recent research into the effects of functional oligosaccharides on intestinal health.

Subjects

OLIGOSACCHARIDES; INTESTINAL diseases; INFLAMMATORY bowel diseases; THERAPEUTICS; DIGESTIVE organs; DEGREE of polymerization

Publication

Molecules, 2022, Vol 27, Issue 21, p7622

ISSN

1420-3049

Publication type

Academic Journal

DOI

10.3390/molecules27217622

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