Works matching DE "POLO-like kinases"

Results: 147

Structural basis for the inhibition of Polo-like kinase 1.

Published in:

Nature Structural & Molecular Biology, 2013, v. 20, n. 9, p. 1047, doi. 10.1038/nsmb.2623

By:

Xu, Jun;
Shen, Chen;
Wang, Tao;
Quan, Junmin

Publication type:

Article

Plk1 inhibition leads to a failure of mitotic division during the first mitotic division in pig embryos.

Published in:

Journal of Assisted Reproduction & Genetics, 2017, v. 34, n. 3, p. 399, doi. 10.1007/s10815-016-0864-4

By:

Zhang, Zixiao;
Chen, Changchao;
Cui, Panpan;
Liao, Yaya;
Yao, Lingyun;
Zhang, Yue;
Rui, Rong;
Ju, Shiqiang

Publication type:

Article

Polo-Like Kinase 4 (PLK4) Is Overexpressed in Central Nervous System Neuroblastoma (CNS-NB).

Published in:

Bioengineering (Basel), 2018, v. 5, n. 4, p. 1, doi. 10.3390/bioengineering5040096

By:

Bailey, Anders W.;
Suri, Amreena;
Chou, Pauline M.;
Pundy, Tatiana;
Gadd, Samantha;
Raimondi, Stacey L.;
Tomita, Tadanori;
Sredni, Simone Treiger

Publication type:

Article

GSK461364A, a Polo-Like Kinase-1 Inhibitor Encapsulated in Polymeric Nanoparticles for the Treatment of Glioblastoma Multiforme (GBM).

Published in:

Bioengineering (Basel), 2018, v. 5, n. 4, p. 1, doi. 10.3390/bioengineering5040083

By:

Velpurisiva, Praveena;
Piel, Brandon P.;
Lepine, Jack;
Rai, Prakash

Publication type:

Article

Another string to the polo bow: a new mitotic role of PLK1 in centromere protection.

Published in:

2019

By:

Olukoga, Tomisin;
Fernández-Casañas, María;
Chan, Kok-Lung

Publication type:

Opinion

High Expression of Polo-Like Kinase 1 Is Associated with Early Development of Hepatocellular Carcinoma.

Published in:

International Journal of Genomics, 2014, p. 1, doi. 10.1155/2014/312130

By:

Wei Sun;
Qi Su;
Xiankui Cao;
Bin Shang;
Aishan Chen;
Hongzhuan Yin;
Baolin Liu

Publication type:

Article

Augmented expression of Polo-like kinase 1 is a strong predictor of shorter cancer-specific overall survival in early stage breast cancer at 15-year follow-up.

Published in:

Oncology Letters, 2016, v. 12, n. 3, p. 1667, doi. 10.3892/ol.2016.4890

By:

DONIZY, PIOTR;
HALON, AGNIESZKA;
SUROWIAK, PAWEL;
KACZOROWSKI, MACIEJ;
KOZYRA, CYPRIAN;
MATKOWSKI, RAFAL

Publication type:

Article

An oncoinformatics study to predict the inhibitory potential of recent FDA-approved anti-cancer drugs against human Polo-like kinase 1 enzyme: a step towards dual-target cancer medication.

Published in:

3 Biotech, 2019, v. 9, n. 3, p. 1, doi. 10.1007/s13205-019-1594-y

By:

Rizvi, Syed Mohd. Danish;
Alshammari, Abdulaziz Arif A.;
Almawkaa, Waleed Abdullah;
Ahmed, Abo Bakr F.;
Katamesh, Ahmed;
Alafnan, Ahmed;
Almutairi, Tariq J.;
Alshammari, Rakan F.

Publication type:

Article

Understanding the Polo Kinase machine.

Published in:

Oncogene, 2015, v. 34, n. 37, p. 4799, doi. 10.1038/onc.2014.451

By:

Archambault, V;
Lépine, G;
Kachaner, D

Publication type:

Article

A novel role for Plk4 in regulating cell spreading and motility.

Published in:

Oncogene, 2015, v. 34, n. 26, p. 3441, doi. 10.1038/onc.2014.275

By:

Rosario, C O;
Kazazian, K;
Zih, F S W;
Brashavitskaya, O;
Haffani, Y;
Xu, R S Z;
George, A;
Dennis, J W;
Swallow, C J

Publication type:

Article

PLK1 as a potential prognostic marker of gastric cancer through MEK-ERK pathway on PDTX models.

Published in:

OncoTargets & Therapy, 2018, v. 11, p. 6239, doi. 10.2147/OTT.S169880

By:

Dang, Sheng-Chun;
Fan, Yi-Yi;
Cui, Lei;
Chen, Ji-Xiang;
Qu, Jian-Guo;
Gu, Min

Publication type:

Article

Helicobacter pylori promotes gastric epithelial cell survival through the PLK1/PI3K/Akt pathway.

Published in:

OncoTargets & Therapy, 2018, v. 11, p. 5703, doi. 10.2147/OTT.S164749

By:

Xu, Wenting;
Huang, Ying;
Yang, Zhen;
Hu, Yi;
Shu, Xu;
Xie, Chuan;
He, Cong;
Zhu, Yin;
Lu, Nonghua

Publication type:

Article

Volasertib for AML: clinical use and patient consideration.

Published in:

OncoTargets & Therapy, 2015, v. 8, p. 1761, doi. 10.2147/OTT.S60762

By:

Zhonglin Hao;
Kota, Vamsi

Publication type:

Article

A polo-like kinase modulates cytokinesis and flagella biogenesis in Giardia lamblia.

Published in:

Parasites & Vectors, 2021, v. 14, n. 1, p. 1, doi. 10.1186/s13071-021-04687-5

By:

Park, Eun-Ah;
Kim, Juri;
Shin, Mee Young;
Park, Soon-Jung

Publication type:

Article

A polo-like kinase modulates cytokinesis and flagella biogenesis in Giardia lamblia.

Published in:

Parasites & Vectors, 2021, v. 14, n. 1, p. 1, doi. 10.1186/s13071-021-04687-5

By:

Park, Eun-Ah;
Kim, Juri;
Shin, Mee Young;
Park, Soon-Jung

Publication type:

Article

QSAR, molecular docking, design, and pharmacokinetic analysis of 2-(4-fluorophenyl) imidazol-5-ones as anti-breast cancer drug compounds against MCF-7 cell line.

Published in:

Journal of Bioenergetics & Biomembranes, 2020, v. 52, n. 6, p. 475, doi. 10.1007/s10863-020-09858-0

By:

Lawal, Hadiza Abdulrahman;
Uzairu, Adamu;
Uba, Sani

Publication type:

Article

Plk1 in Asthma: Ready for Primetime?

Published in:

2022

By:

Kit Chung Tam, John;
Thai Tran

Publication type:

Editorial

Plk1 is essential for proper chromosome segregation during meiosis I/meiosis II transition in pig oocytes.

Published in:

Reproductive Biology & Endocrinology, 2017, v. 15, p. 1, doi. 10.1186/s12958-017-0289-7

By:

Zixiao Zhang;
Changchao Chen;
Liying Ma;
Qiuchen Yu;
Shuai Li;
Abbasi, Benazir;
Jiayi Yang;
Rong Rui;
Shiqiang Ju

Publication type:

Article

MicroRNA-27a promotes proliferation and suppresses apoptosis by targeting PLK2 in laryngeal carcinoma.

Published in:

BMC Cancer, 2014, v. 14, p. 1, doi. 10.1186/1471-2407-14-678

By:

Yuan Tian;
Shuang Fu;
Guang-Bin Qiu;
Zhen-Ming Xu;
Ning Liu;
Xiao-Wen Zhang;
Sheng Chen;
Ye Wang;
Kai-Lai Sun;
Wei-Neng Fu

Publication type:

Article

Polo-like kinase 1 (PLK1) inhibition suppresses cell growth and enhances radiation sensitivity in medulloblastoma cells.

Published in:: BMC Cancer, 2012, v. 12, n. 1, p. 80, doi. 10.1186/1471-2407-12-80
Publication type:: Article

Downregulation of microRNA-100 correlates with tumor progression and poor prognosis in hepatocellular carcinoma.

Published in:

Molecular & Cellular Biochemistry, 2013, v. 383, n. 1/2, p. 49, doi. 10.1007/s11010-013-1753-0

By:

Chen, Ping;
Zhao, Xia;
Ma, Liang

Publication type:

Article

Analyses of expressions and prognostic values of Polo-like kinases in non-small cell lung cancer.

Published in:

Journal of Cancer Research & Clinical Oncology, 2020, v. 146, n. 10, p. 2447, doi. 10.1007/s00432-020-03288-6

By:

Zeng, Yu;
Li, Nanhong;
Liu, Wang;
Zeng, Mingqing;
Cheng, Junfen;
Huang, Jian

Publication type:

Article

Mining antiviral complexity.

Published in:

Nature Immunology, 2012, v. 13, n. 1, p. 19, doi. 10.1038/ni.2197

By:

Fehervari, Zoltan

Publication type:

Article

Ndj1, a telomere-associated protein, regulates centrosome separation in budding yeast meiosis.

Published in:

Journal of Cell Biology, 2015, v. 209, n. 2, p. 247, doi. 10.1083/jcb.201408118

By:

Ping Li;
Yize Shao;
Hui Jin;
Hong-Guo Yu

Publication type:

Article

Interdomain allosteric regulation of Polo kinase by Aurora B and Map205 is required for cytokinesis.

Published in:

Journal of Cell Biology, 2014, v. 207, n. 2, p. 201, doi. 10.1083/jcb.201408081

By:

Kachaner, David;
Pinson, Xavier;
El Kadhi, Khaled Ben;
Normandin, Karine;
Talje, Lama;
Lavoie, Hugo;
Lépine, Guíllaume;
Carréno, Sébastien;
Kwok, Benjamin H.;
Hickson, Gilles R.;
Archambault, Vincent

Publication type:

Article

Polo-like kinase 4 and Stromal antigen 3 are not associated with recurrent pregnancy loss caused by embryonic aneuploidy.

Published in:

Human Genome Variation, 2020, v. 7, n. 1, p. 1, doi. 10.1038/s41439-020-0106-2

By:

Yoshihara, Hiroyuki;
Sugiura-Ogasawara, Mayumi;
Ozawa, Fumiko;
Kitaori, Tamao;
Ozaki, Yasuhiko;
Aoki, Koji;
Shibata, Yasuhiro;
Ugawa, Shinya;
Nishiyama, Takeshi;
Omae, Yosuke;
Tokunaga, Katsushi

Publication type:

Article

Phosphorylation of PLK3 Is Controlled by Protein Phosphatase 6.

Published in:

Cells (2073-4409), 2020, v. 9, n. 6, p. 1506, doi. 10.3390/cells9061506

By:

Aquino Perez, Cecilia;
Palek, Matous;
Stolarova, Lenka;
von Morgen, Patrick;
Macurek, Libor

Publication type:

Article

Cardiac glycosides block cancer growth through HIF-1α- and NF-κB-mediated Plk1.

Published in:

Carcinogenesis, 2013, v. 34, n. 8, p. 1870, doi. 10.1093/carcin/bgt136

By:

Xie, Chuan-Ming;
Liu, Xiao-Yu;
Yu, Sidney;
Cheng, Christopher H.K.

Publication type:

Article

Global assessment of its network dynamics reveals that the kinase Plk1 inhibits the phosphatase PP6 to promote Aurora A activity.

Published in:

Science Signaling, 2018, v. 11, n. 530, p. 1, doi. 10.1126/scisignal.aaq1441

By:

Kettenbach, Arminja N.;
Schlosser, Kate A.;
Lyons, Scott P.;
Nasa, Isha;
Gui, Jiang;
Adamo, Mark E.;
Gerber, Scott A.

Publication type:

Article

Mitotic phosphotyrosine network analysis reveals that tyrosine phosphorylation regulates Polo-like kinase 1 (PLK1).

Published in:

Science Signaling, 2016, v. 9, n. 458, p. 1, doi. 10.1126/scisignal.aah3525

By:

Caron, Danielle;
Byrne, Dominic P.;
Thebault, Philippe;
Soulet, Denis;
Landry, Christian R.;
Eyers, Patrick A.;
Elowe, Sabine

Publication type:

Article

Upregulated Polo-Like Kinase 1 Expression Correlates with Inferior Survival Outcomes in Rectal Cancer.

Published in:

PLoS ONE, 2015, v. 10, n. 6, p. 1, doi. 10.1371/journal.pone.0129313

By:

Tut, T. G.;
Lim, S. H. S.;
Dissanayake, I. U.;
Descallar, J.;
Chua, W.;
Ng, W.;
de Souza, P.;
Shin, J-S.;
Lee, C. S.

Publication type:

Article

Multiple Requirements of PLK1 during Mouse Oocyte Maturation.

Published in:

PLoS ONE, 2015, v. 10, n. 2, p. 1, doi. 10.1371/journal.pone.0116783

By:

Solc, Petr;
Kitajima, Tomoya S.;
Yoshida, Shuhei;
Brzakova, Adela;
Kaido, Masako;
Baran, Vladimir;
Mayer, Alexandra;
Samalova, Pavlina;
Motlik, Jan;
Ellenberg, Jan

Publication type:

Article

Correction: Identification of the PLK2-Dependent Phosphopeptidome by Quantitative Proteomics.

Published in:

PLoS ONE, 2014, v. 9, n. 11, p. 1, doi. 10.1371/journal.pone.0114202

By:

null, null

Publication type:

Article

Identification of the PLK2-Dependent Phosphopeptidomeby Quantitative Proteomics.

Published in:

PLoS ONE, 2014, v. 9, n. 10, p. 1, doi. 10.1371/journal.pone.0111018

By:

Franchin, Cinzia;
Cesaro, Luca;
Pinna, Lorenzo A.;
Arrigoni, Giorgio;
Salvi, Mauro

Publication type:

Article

Design and Synthesis of a Cell-Permeable, Drug-Like Small Molecule Inhibitor Targeting the Polo-Box Domain of Polo-Like Kinase 1.

Published in:

PLoS ONE, 2014, v. 9, n. 9, p. 1, doi. 10.1371/journal.pone.0107432

By:

Srinivasrao, Ganipisetti;
Park, Jung-Eun;
Kim, Sungmin;
Ahn, Mija;
Cheong, Chaejoon;
Nam, Ky-Youb;
Gunasekaran, Pethaiah;
Hwang, Eunha;
Kim, Nam-Hyung;
Shin, Song Yub;
Lee, Kyung S.;
Ryu, Eunkyung;
Bang, Jeong Kyu

Publication type:

Article

Cell Cycle-Dependent Phosphorylation of Theileria annulata Schizont Surface Proteins.

Published in:

PLoS ONE, 2014, v. 9, n. 7, p. 1, doi. 10.1371/journal.pone.0103821

By:

Wiens, Olga;
Xia, Dong;
von Schubert, Conrad;
Wastling, Jonathan M.;
Dobbelaere, Dirk A. E.;
Heussler, Volker T.;
Woods, Kerry L.

Publication type:

Article

Dynamic and Multi-Pharmacophore Modeling for Designing Polo-Box Domain Inhibitors.

Published in:

PLoS ONE, 2014, v. 9, n. 7, p. 1, doi. 10.1371/journal.pone.0101405

By:

Sakkiah, Sugunadevi;
Senese, Silvia;
Yang, Qianfan;
Lee, Keun Woo;
Torres, Jorge Z.

Publication type:

Article

p53-Dependent and Cell Specific Epigenetic Regulation of the Polo-like kinases under Oxidative Stress.

Published in:

PLoS ONE, 2014, v. 9, n. 1, p. 1, doi. 10.1371/journal.pone.0087918

By:

Ward, Alejandra;
Hudson, John W.

Publication type:

Article

Sorcin Links Calcium Signaling to Vesicle Trafficking, Regulates Polo-Like Kinase 1 and Is Necessary for Mitosis.

Published in:

PLoS ONE, 2014, v. 9, n. 1, p. 1, doi. 10.1371/journal.pone.0085438

By:

Lalioti, Vasiliki S.;
Ilari, Andrea;
O'Connell, David J.;
Poser, Elena;
Sandoval, Ignacio V.;
Colotti, Gianni

Publication type:

Article

NFBD1/MDC1 Is Phosphorylated by PLK1 and Controls G2/M Transition through the Regulation of a TOPOIIα-Mediated Decatenation Checkpoint.

Published in:

PLoS ONE, 2013, v. 8, n. 12, p. 1, doi. 10.1371/journal.pone.0082744

By:

Ando, Kiyohiro;
Ozaki, Toshinori;
Hirota, Toru;
Nakagawara, Akira

Publication type:

Article

Polo-Like Kinase 1 (PLK1) Is Involved in Toll-like Receptor (TLR)-Mediated TNF-α Production in Monocytic THP-1 Cells.

Published in:

PLoS ONE, 2013, v. 8, n. 10, p. 1, doi. 10.1371/journal.pone.0078832

By:

Hu, Jinyue;
Wang, Guihua;
Liu, Xueting;
Zhou, Lina;
Jiang, Manli;
Yang, Li

Publication type:

Article

A High-Content Small Molecule Screen Identifies Sensitivity of Glioblastoma Stem Cells to Inhibition of Polo-Like Kinase 1.

Published in:

PLoS ONE, 2013, v. 8, n. 10, p. 1, doi. 10.1371/journal.pone.0077053

By:

Danovi, Davide;
Folarin, Amos;
Gogolok, Sabine;
Ender, Christine;
Elbatsh, Ahmed M. O.;
Engström, Pär G.;
Stricker, Stefan H.;
Gagrica, Sladjana;
Georgian, Ana;
Yu, Ding;
U, Kin Pong;
Harvey, Kevin J.;
Ferretti, Patrizia;
Paddison, Patrick J.;
Preston, Jane E.;
Abbott, N. Joan;
Bertone, Paul;
Smith, Austin;
Pollard, Steven M.

Publication type:

Article

Polo-Like Kinase 1 Inhibits the Activity of Positive Transcription Elongation Factor of RNA Pol II b (P-TEFb).

Published in:

PLoS ONE, 2013, v. 8, n. 8, p. 1, doi. 10.1371/journal.pone.0072289

By:

Jiang, Liangzhen;
Huang, Yan;
Deng, Min;
Liu, Ting;
Lai, Wenbin;
Ye, Xin

Publication type:

Article

A Novel Anti-Tumor Inhibitor Identified by Virtual Screen with PLK1 Structure and Zebrafish Assay.

Published in:

PLoS ONE, 2013, v. 8, n. 4, p. 1, doi. 10.1371/journal.pone.0053317

By:

Lu, Jing;
Xin, Shengchang;
Meng, Huan;
Veldman, Matt;
Schoenfeld, David;
Che, Chao;
Yan, Ruibin;
Zhong, Hanbing;
Li, Song;
Lin, Shuo

Publication type:

Article

The Polo-Like Kinase 1 (PLK1) Inhibitor NMS-P937 Is Effective in a New Model of Disseminated Primary CD56+ Acute Monoblastic Leukaemia.

Published in:

PLoS ONE, 2013, v. 8, n. 3, p. 1, doi. 10.1371/journal.pone.0058424

By:

Casolaro, Alessia;
Golay, Josee;
Albanese, Clara;
Ceruti, Roberta;
Patton, Veronica;
Cribioli, Sabrina;
Pezzoni, Alice;
Losa, Marco;
Texido, Gemma;
Giussani, Ursula;
Marchesi, Francesco;
Amboldi, Nadia;
Valsasina, Barbara;
Bungaro, Silvia;
Cazzaniga, Gianni;
Rambaldi, Alessandro;
Introna, Martino;
Pesenti, Enrico;
Alzani, Rachele

Publication type:

Article

Hormonal Induction of Polo-Like Kinases (Plks) and Impact of Plk2 on Cell Cycle Progression in the Rat Ovary.

Published in:

PLoS ONE, 2012, v. 7, n. 8, p. 1, doi. 10.1371/journal.pone.0041844

By:

Feixue Li;
Misung Jo;
Curry Jr., Thomas E.;
Jing Liu;
Lobaccaro, Jean-Marc A.

Publication type:

Article

Downregulation of Polo-Like Kinase 4 in Hepatocellular Carcinoma Associates with Poor Prognosis.

Published in:

PLoS ONE, 2012, v. 7, n. 7, p. 1, doi. 10.1371/journal.pone.0041293

By:

Lili Liu;
Chris Zhiyi Zhang;
Muyan Cai;
Jia Fu;
Chen, George Gong;
Jingping Yun

Publication type:

Article

The Centrosomal Kinase Plk1 Localizes to the Transition Zone of Primary Cilia and Induces Phosphorylation of Nephrocystin-1.

Published in:

PLoS ONE, 2012, v. 7, n. 6, p. 1, doi. 10.1371/journal.pone.0038838

By:

Seeger-Nukpezah, Tamina;
Liebau, Max C.;
Höpker, Katja;
Lamkemeyer, Tobias;
Benzing, Thomas;
Golemis, Erica A.;
Schermer, Bernhard

Publication type:

Article

The Structural Basis of Localizing Polo-Like Kinase to the Flagellum Attachment Zone in Trypanosoma brucei.

Published in:

PLoS ONE, 2011, v. 6, n. 11, p. 1, doi. 10.1371/journal.pone.0027303

By:

Lu Sun;
Wang, Ching C.

Publication type:

Article

Microenvironmental Influence on Pre-Clinical Activity of Polo-Like Kinase Inhibition in Multiple Myeloma: Implications for Clinical Translation.

Published in:

PLoS ONE, 2011, v. 6, n. 7, p. 1, doi. 10.1371/journal.pone.0020226

By:

McMillin, Douglas W.;
Delmore, Jake;
Negri, Joseph;
Ooi, Melissa;
Klippel, Steffen;
Miduturu, Chandrasekhar V.;
Gray, Nathanael S.;
Richardson, Paul G.;
Anderson, Kenneth C.;
Kung, Andrew L.;
Mitsiades, Constantine S.

Publication type:

Article