Works matching AU Enza Lacivita
Results: 42
Inflammaging and Immunosenescence in the Post‐COVID Era: Small Molecules, Big Challenges.
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- ChemMedChem, 2025, v. 20, n. 6, p. 1, doi. 10.1002/cmdc.202400672
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Towards metabolically stable 5-HT receptor ligands: a study on 1-arylpiperazine derivatives and related isosters.
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- Experimental Brain Research, 2013, v. 230, n. 4, p. 569, doi. 10.1007/s00221-013-3498-0
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Synthesis and binding profile of constrained analogues of N-[4-(4-arylpiperazin-1-yl)butyl]-3-methoxybenzamides, a class of potent dopamine D3 receptor ligands.
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- Journal of Pharmacy & Pharmacology, 2006, v. 58, n. 2, p. 209
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Design and synthesis of long-chain arylpiperazines with mixed affinity for serotonin transporter (SERT) and 5-HT1A receptor.
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- Journal of Pharmacy & Pharmacology, 2005, v. 57, n. 10, p. 1319
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Studies on 1-arylpiperazine derivatives with affinity for rat 5-HT<sub>7</sub> and 5-HT<sub>1A</sub> receptors.
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- Journal of Pharmacy & Pharmacology, 2004, v. 56, n. 2, p. 247
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Microglia Depletion Attenuates the Pro-Resolving Activity of the Formyl Peptide Receptor 2 Agonist AMS21 Related to Inhibition of Inflammasome NLRP3 Signalling Pathway: A Study of Organotypic Hippocampal Cultures.
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- Cells (2073-4409), 2023, v. 12, n. 21, p. 2570, doi. 10.3390/cells12212570
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Time-Dependent Protective and Pro-Resolving Effects of FPR2 Agonists on Lipopolysaccharide-Exposed Microglia Cells Involve Inhibition of NF-κB and MAPKs Pathways.
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- Cells (2073-4409), 2021, v. 10, n. 9, p. 2373, doi. 10.3390/cells10092373
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The N-Formyl Peptide Receptor 2 (FPR2) Agonist MR-39 Exhibits Anti-Inflammatory Activity in LPS-Stimulated Organotypic Hippocampal Cultures.
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- Cells (2073-4409), 2021, v. 10, n. 6, p. 1524, doi. 10.3390/cells10061524
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In Vitro and In Vivo Evaluation of N-{2-[4-(3-Cyanopyridin-2-yl)piperazin-1-yl]ethyl}-3-[<sup>11</sup>C]methoxybenzamide, a Positron Emission Tomography (PET) Radioligand for Dopamine D<sub>4</sub> Receptors, in Rodents.
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- Chemistry & Biodiversity, 2014, v. 11, n. 9, p. 1298, doi. 10.1002/cbdv.201400178
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Design, Synthesis, Lipophilic Properties, and Binding Affinities of Potential Ligands in Positron Emission Tomography (PET) for Visualization of Brain Dopamine D<sub>4</sub> Receptors.
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- Chemistry & Biodiversity, 2014, v. 11, n. 2, p. 299, doi. 10.1002/cbdv.201300194
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Selective agonists for serotonin 7 (5-HT<sub>7</sub>) receptor and their applications in preclinical models: an overview.
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- Reviews in the Neurosciences, 2014, v. 25, n. 3, p. 401, doi. 10.1515/revneuro-2014-0009
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Modulatory effects following subchronic stimulation of brain 5-HT7-R system in mice and rats.
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- Reviews in the Neurosciences, 2014, v. 25, n. 3, p. 383, doi. 10.1515/revneuro-2014-0007
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Serotonin 5- HT7 receptor increases the density of dendritic spines and facilitates synaptogenesis in forebrain neurons.
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- Journal of Neurochemistry, 2017, v. 141, n. 5, p. 647, doi. 10.1111/jnc.13962
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Persistent modification of forebrain networks and metabolism in rats following adolescent exposure to a 5-HT7 receptor agonist.
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- Psychopharmacology, 2015, v. 232, n. 1, p. 75, doi. 10.1007/s00213-014-3639-6
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Activation of 5‐HT7 receptor by administration of its selective agonist, LP‐211, modifies explorative‐curiosity behavior in rats in two paradigms which differ in visuospatial parameters.
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- CNS Neuroscience & Therapeutics, 2018, v. 24, n. 8, p. 712, doi. 10.1111/cns.12812
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Interplay between Serotonin 5- HT<sub>1A</sub> and 5- HT<sub>7</sub> Receptors in Depressive Disorders.
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- CNS Neuroscience & Therapeutics, 2014, v. 20, n. 7, p. 582, doi. 10.1111/cns.12247
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Serotonin 5‐HT7 receptors require cyclin‐dependent kinase 5 to rescue hippocampal synaptic plasticity in a mouse model of Fragile X Syndrome.
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- European Journal of Neuroscience, 2021, v. 54, n. 1, p. 4124, doi. 10.1111/ejn.15246
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5-HT<sub>7 </sub>Receptors Regulate Excitatory-Inhibitory Balance in Mouse Spinal Cord Dorsal Horn.
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- Frontiers in Molecular Neuroscience, 2022, v. 15, p. 1, doi. 10.3389/fnmol.2022.946159
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Increase of Capsaicin-Induced Trigeminal Fos-Like Immunoreactivity by 5-HT<sub>7</sub> Receptors.
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- Headache: The Journal of Head & Face Pain, 2011, v. 51, n. 10, p. 1511, doi. 10.1111/j.1526-4610.2011.02011.x
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The N-Formyl Peptide Receptor 2 (FPR2) Agonist MR-39 Improves Ex Vivo and In Vivo Amyloid Beta (1–42)-Induced Neuroinflammation in Mouse Models of Alzheimer's Disease.
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- Molecular Neurobiology, 2021, v. 58, n. 12, p. 6203, doi. 10.1007/s12035-021-02543-2
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Pharmacological Stimulation of the Brain Serotonin Receptor 7 as a Novel Therapeutic Approach for Rett Syndrome.
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- Neuropsychopharmacology, 2014, v. 39, n. 11, p. 2506, doi. 10.1038/npp.2014.105
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Evaluating the effect of R-Baclofen and LP-211 on autistic behavior of the BTBR and Fmr1-KO mouse models.
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- Frontiers in Neuroscience, 2023, v. 17, p. 1, doi. 10.3389/fnins.2023.1087788
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Design, Synthesis, and Characterization of a Novel Fluoroprobe for Live Human Islet Cell Imaging of Serotonin 5‐HT<sub>1A</sub> Receptor.
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- ChemMedChem, 2022, v. 17, n. 10, p. 1, doi. 10.1002/cmdc.202100759
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Functional N-Formyl Peptide Receptor 2 (FPR2) Antagonists Based on the Ureidopropanamide Scaffold Have Potential To Protect Against Inflammation-Associated Oxidative Stress.
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- ChemMedChem, 2017, v. 12, n. 22, p. 1839, doi. 10.1002/cmdc.201700429
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Stimulation of 5- HT7 receptor during adolescence determines its persistent upregulation in adult rat forebrain areas.
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- Synapse, 2015, v. 69, n. 11, p. 533, doi. 10.1002/syn.21846
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Emotional and risk seeking behavior after prepuberal subchronic or adult acute stimulation of 5-HT7-Rs in naples high excitability rats.
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- Synapse, 2014, v. 68, n. 4, p. 159, doi. 10.1002/syn.21724
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Low Basicity as a Characteristic for Atypical Ligands of Serotonin Receptor 5-HT2.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 3, p. 1035, doi. 10.3390/ijms22031035
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Mitochondrial Membranes of Human SH-SY5Y Neuroblastoma Cells Express Serotonin 5-HT 7 Receptor.
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- International Journal of Molecular Sciences, 2020, v. 21, n. 24, p. 9629, doi. 10.3390/ijms21249629
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Design and Synthesis of Arylpiperazine Serotonergic/Dopaminergic Ligands with Neuroprotective Properties.
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- Molecules, 2022, v. 27, n. 4, p. 1297, doi. 10.3390/molecules27041297
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σ 2 Receptor and Its Role in Cancer with Focus on a MultiTarget Directed Ligand (MTDL) Approach.
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- Molecules, 2021, v. 26, n. 12, p. 3743, doi. 10.3390/molecules26123743
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Multitarget-Directed Ligands Hitting Serotonin Receptors: A Medicinal Chemistry Survey.
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- Pharmaceuticals (14248247), 2024, v. 17, n. 9, p. 1238, doi. 10.3390/ph17091238
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Allosteric Modulators of Serotonin Receptors: A Medicinal Chemistry Survey.
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- Pharmaceuticals (14248247), 2024, v. 17, n. 6, p. 695, doi. 10.3390/ph17060695
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Behavioral, Anti-Inflammatory, and Neuroprotective Effects of a Novel FPR2 Agonist in Two Mouse Models of Autism.
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- Pharmaceuticals (14248247), 2022, v. 15, n. 2, p. 161, doi. 10.3390/ph15020161
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Radiosynthesis and in vivo Evaluation of Carbon-11 (2 S)-3-(1 H-Indol-3-yl)-2-{[(4-methoxyphenyl)carbamoyl]amino}- N-{[1-(5-methoxypyridin-2-yl)cyclohexyl]methyl}propanamide: An Attempt to Visualize Brain Formyl Peptide Receptors in Mouse Models of Neuroinflammation
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- Chemistry & Biodiversity, 2016, v. 13, n. 7, p. 875, doi. 10.1002/cbdv.201500281
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Long-lasting beneficial effects of central serotonin receptor 7 stimulation in female mice modeling Rett syndrome.
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- Frontiers in Behavioral Neuroscience, 2015, v. 9, p. 1, doi. 10.3389/fnbeh.2015.00086
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Novel agonists for serotonin 5-HT<sub>7</sub> receptors reverse metabotropic glutamate receptor-mediated long-term depression in the hippocampus of wild-type and Fmr1 KO mice, a model of Fragile X Syndrome.
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- Frontiers in Behavioral Neuroscience, 2015, v. 9, p. 1, doi. 10.3389/fnbeh.2015.00065
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Activation of 5-HT7 receptor stimulates neurite elongation through mTOR, Cdc42 and actin filaments dynamics.
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- Frontiers in Behavioral Neuroscience, 2015, v. 9, p. 1, doi. 10.3389/fnbeh.2015.00062
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Differential responses to acute administration of a new 5-HT7-R agonist as a function of adolescent pre-treatment: phMRI and immuno-histochemical study.
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- Frontiers in Behavioral Neuroscience, 2014, v. 8, p. 1, doi. 10.3389/fnbeh.2014.00427
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Activation of Serotonin 5-HT<sub>7</sub> Receptors Modulates Hippocampal Synaptic Plasticity by Stimulation of Adenylate Cyclases and Rescues Learning and Behavior in a Mouse Model of Fragile X Syndrome.
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- Frontiers in Molecular Neuroscience, 2018, p. 1, doi. 10.3389/fnmol.2018.00353
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P3‐047: OPTIMIZATION OF FORMYL PEPTIDE RECEPTOR 2 (FPR2) AGONISTS WITH NEUROPROTECTIVE PROPERTIES IN MODELS OF NEUROINFLAMMATION RELATED TO ALZHEIMER'S DISEASE.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P944, doi. 10.1016/j.jalz.2019.06.3073
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Prepuberal Stimulation of 5-HT7-R by LP-211 in a Rat Model of Hyper-Activity and Attention-Deficit: Permanent Effects on Attention, Brain Amino Acids and Synaptic Markers in the Fronto-Striatal Interface.
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- PLoS ONE, 2014, v. 9, n. 4, p. 1, doi. 10.1371/journal.pone.0083003
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Prior Activation of 5-HT7 Receptors Modulates the Conditioned Place Preference With Methylphenidate.
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- Frontiers in Behavioral Neuroscience, 2019, p. 1, doi. 10.3389/fnbeh.2019.00208
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