Works matching DE "MITOGEN-activated protein kinase kinase"

Results: 306

Low‐molecular mimetics of nerve growth factor and brain‐derived neurotrophic factor: Design and pharmacological properties.

Published in:

Medicinal Research Reviews, 2021, v. 41, n. 5, p. 2746, doi. 10.1002/med.21721

By:

Gudasheva, Tatiana A.;
Povarnina, Polina Y.;
Tarasiuk, Aleksey V.;
Seredenin, Sergey B.

Publication type:

Article

Rutaecarpine attenuates high glucose‐induced damage in AC16 cardiomyocytes by suppressing the MAPK pathway.

Published in:

Journal of Applied Toxicology, 2023, v. 43, n. 9, p. 1306, doi. 10.1002/jat.4465

By:

Lv, Jun;
Ji, Miaomiao;
Yang, Han;
Wang, Chao;
Zhang, Lingyan;
Ni, Hongzao

Publication type:

Article

Embelin as a Novel Inhibitor of PKC in the Prevention of Platelet Activation and Thrombus Formation.

Published in:

Journal of Clinical Medicine, 2019, v. 8, n. 10, p. 1724, doi. 10.3390/jcm8101724

By:

Li, Jiun Yi;
Chen, Ray Jade;
Huang, Li Ting;
Lee, Tzu Yin;
Lu, Wan Jung;
Lin, Kuan Hung

Publication type:

Article

Rice calcium/calmodulin-dependent protein kinase directly phosphorylates a mitogen-activated protein kinase kinase to regulate abscisic acid responses.

Published in:

Plant Cell, 2021, v. 33, n. 5, p. 1790, doi. 10.1093/plcell/koab071

By:

Chen, Min;
Ni, Lan;
Chen, Jing;
Sun, Manman;
Qin, Caihua;
Zhang, Gang;
Zhang, Aying;
Jiang, Mingyi

Publication type:

Article

Arabidopsis Homologs of Nucleus- and Phragmoplast-Localized Kinase 2 and 3 and Mitogen-Activated Protein Kinase 4 Are Essential for Microtubule Organization.

Published in:

Plant Cell, 2010, v. 22, n. 3, p. 755, doi. 10.1105/tpc.109.071746

By:

Beck, Martina;
Komis, George;
Müller, Jens;
Menzel, Diedrik;
šamaj, Jozef

Publication type:

Article

Peroxisome proliferator-activated receptor γ is essential for secretion of ANP induced by prostaglandin D2 in the beating rat atrium.

Published in:

Korean Journal of Physiology & Pharmacology, 2017, v. 21, n. 3, p. 293, doi. 10.4196/kjpp.2017.21.3.293

By:

Ying Zhang;
Xiang Li;
Li-Ping Liu;
Lan Hong;
Xia Liu;
Bo Zhang;
Cheng-Zhe Wu;
Xun Cui

Publication type:

Article

Role of JNK activation in paclitaxel-induced apoptosis in human head and neck squamous cell carcinoma.

Published in:

Oncology Letters, 2021, v. 22, n. 4, p. N.PAG, doi. 10.3892/ol.2021.12966

By:

Lan, Yu-Yan;
Chen, Ying-Hui;
Liu, Cheng;
Tung, Kuo-Lung;
Wu, Yen-Ting;
Lin, Sheng-Chieh;
Wu, Chin-Han;
Chang, Hong-Yi;
Chen, Yung-Chia;
Huang, Bu-Miin

Publication type:

Article

Identification of biomarkers and their functions in dasatinib-resistant pancreatic cancer using bioinformatics analysis.

Published in:

Oncology Letters, 2019, v. 18, n. 1, p. 197, doi. 10.3892/ol.2019.10281

By:

Wei, Jingsun;
Han, Rongbo;
Su, Xinyu;
Chen, Yuetong;
Shi, Junfeng;
Cui, Xiaowen;
Zhang, Honghong;
Gong, Yang;
Chu, Xia;
Chen, Jinfei

Publication type:

Article

Stevioside induced cytotoxicity in colon cancer cells via reactive oxygen species and mitogen-activated protein kinase signaling pathways-mediated apoptosis.

Published in:

Oncology Letters, 2017, v. 13, n. 4, p. 2337, doi. 10.3892/ol.2017.5744

By:

HAI-PENG REN;
XIAO-YAN YIN;
HAI-YING YU;
HAI-FENG XIAO

Publication type:

Article

miR-141 promotes colon cancer cell proliferation by inhibiting MAP2K4.

Published in:

Oncology Letters, 2017, v. 13, n. 3, p. 1665, doi. 10.3892/ol.2017.5653

By:

LEI DING;
LI-LI YU;
NING HAN;
BU-TIAN ZHANG

Publication type:

Article

Targeting the Ras/Raf/MEK/ERK pathway in hepatocellular carcinoma (Review).

Published in:

Oncology Letters, 2017, v. 13, n. 3, p. 1041, doi. 10.3892/ol.2017.5557

By:

SUFANG YANG;
GUOHUA LIU

Publication type:

Article

Overexpression of MEKK2 is associated with colorectal carcinogenesis.

Published in:

Oncology Letters, 2013, v. 6, n. 5, p. 1333, doi. 10.3892/ol.2013.1553

By:

LI JIANG;
MEIJIN HUANG;
LEI WANG;
XINJUAN FAN;
PUNING WANG;
DAOHAI WANG;
XINHUI FU;
JIANPING WANG

Publication type:

Article

Clinical presentation and management of uveal melanoma (Review).

Published in:

Molecular & Clinical Oncology, 2016, v. 5, n. 6, p. 675, doi. 10.3892/mco.2016.1037

By:

RODRÍGUEZ, ABELARDO;
DUEÑAS-GONZALEZ, ALFONSO;
DELGADO-PELAYO, SARAI

Publication type:

Article

Berberine ameliorates erectile dysfunction in rats with streptozotocin‐induced diabetes mellitus through the attenuation of apoptosis by inhibiting the SPHK1/S1P/S1PR2 and MAPK pathways.

Published in:

Andrology, 2022, v. 10, n. 2, p. 404, doi. 10.1111/andr.13119

By:

Liu, Kang;
Sun, Taotao;
Luan, Yang;
Chen, Yinwei;
Song, Jingyu;
Ling, Le;
Yuan, Penghui;
Li, Rui;
Cui, Kai;
Ruan, Yajun;
Lan, Ruzhu;
Wang, Tao;
Wang, Shaogang;
Liu, Jihong;
Rao, Ke

Publication type:

Article

Amentoflavone-Enriched Selaginella rossii Protects against Ultraviolet- and Oxidative Stress-Induced Aging in Skin Cells.

Published in:

Life (2075-1729), 2022, v. 12, n. 12, p. 2106, doi. 10.3390/life12122106

By:

Lee, Hwa;
Kim, Soo-Yong;
Lee, Sang Woo;
Kwak, Sehan;
Li, Hulin;
Piao, Renzhe;
Park, Ho-Yong;
Choi, Sangho;
Jeong, Tae-Sook

Publication type:

Article

mTORC1 upregulation via ERK-dependent gene expression change confers intrinsic resistance to MEK inhibitors in oncogenic KRas-mutant cancer cells.

Published in:

Oncogene, 2015, v. 34, n. 45, p. 5607, doi. 10.1038/onc.2015.16

By:

Komatsu, N;
Fujita, Y;
Matsuda, M;
Aoki, K

Publication type:

Article

Oncogenic Ras inhibits IRF1 to promote viral oncolysis.

Published in:

Oncogene, 2015, v. 34, n. 30, p. 3985, doi. 10.1038/onc.2014.331

By:

Komatsu, Y;
Christian, S L;
Ho, N;
Pongnopparat, T;
Licursi, M;
Hirasawa, K

Publication type:

Article

Regulation of the mitogen-activated protein kinase kinase (MEK)-1 by NAD+-dependent deacetylases.

Published in:

Oncogene, 2015, v. 34, n. 6, p. 798, doi. 10.1038/onc.2014.39

By:

Yeung, F;
Ramsey, C S;
Popko-Scibor, A E;
Allison, D F;
Gray, L G;
Shin, M;
Kumar, M;
Li, D;
McCubrey, J A;
Mayo, M W

Publication type:

Article

Mitogen-activated protein kinase 6 regulates NPR1 gene expression and activation during leaf senescence induced by salicylic acid.

Published in:

Journal of Experimental Botany, 2014, v. 65, n. 22, p. 6513, doi. 10.1093/jxb/eru369

By:

Chai, Jinyu;
Liu, Jian;
Zhou, Jun;
Xing, Da

Publication type:

Article

Salt-induced subcellular kinase relocation and seedling susceptibility caused by overexpression of Medicago SIMKK in Arabidopsis.

Published in:

Journal of Experimental Botany, 2014, v. 65, n. 9, p. 2335, doi. 10.1093/jxb/eru115

By:

Ovečka, Miroslav;
Takáč, Tomáš;
Komis, George;
Vadovič, Pavol;
Bekešová, Slávka;
Doskočilová, Anna;
Smékalová, Veronika;
Luptovčiak, Ivan;
Šamajová, Olga;
Schweighofer, Alois;
Meskiene, Irute;
Jonak, Claudia;
Křenek, Pavel;
Lichtscheidl, Irene;
Škultéty, Ľudovít;
Hirt, Heribert;
Šamaj, Jozef

Publication type:

Article

Arabidopsis thaliana mitogen-activated protein kinase 6 is involved in seed formation and modulation of primary and lateral root development.

Published in:

Journal of Experimental Botany, 2014, v. 65, n. 1, p. 169, doi. 10.1093/jxb/ert368

By:

López-Bucio, J. S.;
Dubrovsky, J. G.;
Raya-González, J.;
Ugartechea-Chirino, Y.;
López-Bucio, J.;
de Luna-Valdez, L. A.;
Ramos-Vega, M.;
León, P.;
Guevara-García, A. A.

Publication type:

Article

Bioinformatics Analysis of MAPKKK Family Genes in Medicago truncatula.

Published in:

Genes, 2016, v. 7, n. 4, p. 13, doi. 10.3390/genes7040013

By:

Wei Li;
Hanyun Xu;
Ying Liu;
Lili Song;
Changhong Guo;
Yongjun Shu

Publication type:

Article

The new nucleoporin.

Published in:

Nucleus (1949-1034), 2012, v. 3, n. 6, p. 1, doi. 10.4161/nucl.22427

By:

Sarma, Nayan J.;
Willis, Kristine

Publication type:

Article

Panniculitis Associated with MEK Inhibitor Therapy: An Uncommon Adverse Effect.

Published in:

Case Reports in Dermatology, 2017, v. 9, n. 1, p. 80, doi. 10.1159/000461571

By:

Negulescu, Miruna;
Deilhes, Florian;
Sibaud, Vincent;
Tournier, Emilie;
Lamant, Laurence;
Boulinguez, Serge;
Meyer, Nicolas

Publication type:

Article

Trametinib: a MEK inhibitor for management of metastatic melanoma.

Published in:

OncoTargets & Therapy, 2015, v. 8, p. 2251, doi. 10.2147/OTT.S72951

By:

Lugowska, Iwona;
Koseła-Paterczyk, Hanna;
Kozak, Katarzyna;
Rutkowski, Piotr

Publication type:

Article

MOLECULAR CHARACTERIZATION AND SUB-CELLULAR DISTRIBUTION OF JNK AND JIP4 PROTEIN KINASES IN SPERMATOGENESIS AND ACROSOME REACTION OF THE CHINESE MITTEN CRAB ERIOCHEIR SINENSIS H. MILNE EDWARDS, 1853 (CRUSTACEA: BRACHYURA: VARUNIDAE).

Published in:

Journal of Crustacean Biology, 2016, v. 36, n. 5, p. 684, doi. 10.1163/1937240X-00002468

By:

Hongdan Yang;
Qing Li;
Aiqing Yu;
Lin He;
Qun Wang

Publication type:

Article

Clonal evolution and resistance to EGFR blockade in the blood of colorectal cancer patients.

Published in:

Nature Medicine, 2015, v. 21, n. 7, p. 795, doi. 10.1038/nm.3870

By:

Siravegna, Giulia;
Mussolin, Benedetta;
Buscarino, Michela;
Corti, Giorgio;
Cassingena, Andrea;
Crisafulli, Giovanni;
Ponzetti, Agostino;
Cremolini, Chiara;
Amatu, Alessio;
Lauricella, Calogero;
Lamba, Simona;
Hobor, Sebastijan;
Avallone, Antonio;
Valtorta, Emanuele;
Rospo, Giuseppe;
Medico, Enzo;
Motta, Valentina;
Antoniotti, Carlotta;
Tatangelo, Fabiana;
Bellosillo, Beatriz

Publication type:

Article

The transcriptomic landscape and directed chemical interrogation of MLL-rearranged acute myeloid leukemias.

Published in:

Nature Genetics, 2015, v. 47, n. 9, p. 1030, doi. 10.1038/ng.3371

By:

Gendron, Patrick;
Krosl, Jana;
Marinier, Anne;
Lavallée, Vincent-Philippe;
Lemieux, Sébastien;
Sauvageau, Guy;
Boucher, Geneviève;
Hébert, Josée;
Baccelli, Irène;
Wilhelm, Brian;
Meloche, Sylvain;
Barabé, Frédéric

Publication type:

Article

LncPTSR Triggers Vascular Remodeling in Pulmonary Hypertension by Regulating [Ca2+]i in Pulmonary Arterial Smooth Muscle Cells.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2022, v. 66, n. 5, p. 524, doi. 10.1165/rcmb.2020-0480OC

By:

Liyu Deng;
Jidong Chen;
Bin Chen;
Ting Wang;
Lei Yang;
Jing Liao;
Junbo Yi;
Yuqin Chen;
Jian Wang;
Linneman, John;
Yanqin Niu;
Deming Gou

Publication type:

Article

ASK1ng to Delay the Progression of Pulmonary Fibrosis.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2022, v. 66, n. 5, p. 465, doi. 10.1165/rcmb.2022-0026ED

By:

Schuliga, Michael;
Madala, Satish K.

Publication type:

Article

Beauvericin-induced cell apoptosis through the mitogen-activated protein kinase pathway in human nonsmall cell lung cancer A549 cells.

Published in:

Journal of Toxicological Sciences, 2016, v. 41, n. 3, p. 429, doi. 10.2131/jts.41.429

By:

Chien-Lin Lu;
Hen-I Lin;
Bing-Fang Chen;
Guey-Mei Jow

Publication type:

Article

Cyclic guanosine monophosphate does not inhibit gonadotropin-induced activation of mitogenactivated protein kinase 3/1 in pig cumulus-oocyte complexes.

Published in:

Reproductive Biology & Endocrinology, 2015, v. 13, n. 1, p. 1, doi. 10.1186/1477-7827-13-1

By:

Blaha, Milan;
Nemcova, Lucie;
Prochazka, Radek

Publication type:

Article

Potential Chondroprotective Effect of Artemisia annua L. Water Extract on SW1353 Cell.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 5, p. 1901, doi. 10.3390/ijms26051901

By:

Kim, Min Jung;
Yang, Ye Jin;
Heo, Ji Woong;
Son, Jae-dong;
You, Young Zoo;
Yang, Ju-Hye;
Park, Kwang Il

Publication type:

Article

Mitogen- and stress-activated Kinase 1 mediates Epstein-Barr virus latent membrane protein 1-promoted cell transformation in nasopharyngeal carcinoma through its induction of Fra-1 and c-Jun genes.

Published in:

BMC Cancer, 2015, v. 15, n. 1, p. 1, doi. 10.1186/s12885-015-1398-3

By:

Binbin Li;
Zheng Wan;
Guoliang Huang;
Zunnan Huang;
Xiangning Zhang;
Dan Liao;
Shengqun Luo;
Zhiwei He

Publication type:

Article

MicroRNA-21 promotes hepatocellular carcinoma HepG2 cell proliferation through repression of mitogen-activated protein kinase-kinase 3.

Published in:

2013

By:

Guangxian Xu;
Yilin Zhang;
Jun Wei;
Wei Jia;
Zhaohui Ge;
Zhaobo Zhang;
Xiaoming Liu;
Xu, Guangxian;
Zhang, Yilin;
Wei, Jun;
Jia, Wei;
Ge, Zhaohui;
Zhang, Zhaobo;
Liu, Xiaoming

Publication type:

journal article

Farrerol maintains the contractile phenotype of VSMCs via inactivating the extracellular signal-regulated protein kinase 1/2 and p38 mitogen-activated protein kinase signaling.

Published in:

Molecular & Cellular Biochemistry, 2020, v. 475, n. 1/2, p. 249, doi. 10.1007/s11010-020-03878-5

By:

Liu, Enli;
Shi, Shasha;
Li, Jie;
Ge, Rui;
Liang, Taigang;
Li, Qingshan

Publication type:

Article

Inhibitory effect of oblongifolin C on allergic inflammation through the suppression of mast cell activation.

Published in:

Molecular & Cellular Biochemistry, 2015, v. 406, n. 1/2, p. 263, doi. 10.1007/s11010-015-2444-9

By:

Lu, Yue;
Cai, Shuangfan;
Tan, Hongsheng;
Fu, Wenwei;
Zhang, Hong;
Xu, Hongxi

Publication type:

Article

Inhibition of both BRAF and MEK in BRAF mutant melanoma restores compromised dendritic cell (DC) function while having differential direct effects on DC properties.

Published in:

Cancer Immunology, Immunotherapy, 2013, v. 62, n. 4, p. 811, doi. 10.1007/s00262-012-1389-z

By:

Ott, Patrick;
Henry, Trevor;
Baranda, Sonja;
Frleta, Davor;
Manches, Olivier;
Bogunovic, Dusan;
Bhardwaj, Nina

Publication type:

Article

尿石素 A 介导 p38/MAPK 通路抑制破骨细胞活性.

Published in:

Chinese Journal of Tissue Engineering Research / Zhongguo Zuzhi Gongcheng Yanjiu, 2024, v. 28, n. 8, p. 1149, doi. 10.12307/2023.893

By:

黄浩然;
凡一诺;
卫杨文祥;
江梦钰;
方汉军;
王海彬;
陈镇秋;
刘予豪;
周驰

Publication type:

Article

“三通针法”电针调控 Rho/ROCK(Rho kinase) 及 MEK/ERK 信号通路对脊髓损伤大鼠胞浆型磷脂酶 A2 的影响.

Published in:

Chinese Journal of Tissue Engineering Research / Zhongguo Zuzhi Gongcheng Yanjiu, 2023, v. 27, n. 20, p. 3158, doi. 10.12307/2023.447

By:

姚海华;
闵友江;
洪冬英;
王立;
鹿秀云;
杨宜花

Publication type:

Article

琼胶寡糖对脂多糖诱导的巨噬细胞RAW264.7炎症反应的抑制作用.

Published in:

Journal of Chinese Institute of Food Science & Technology / Zhongguo Shipin Xuebao, 2022, v. 22, n. 6, p. 72, doi. 10.16429/j.1009-7848.2022.06.008

By:

郑雅君;
李美秀;
姜泽东;
朱艳冰;
倪辉;
郑明静

Publication type:

Article

Impact of polyphenols on mast cells with special emphasis on the effect of quercetin and luteolin.

Published in:

Central European Journal of Immunology, 2018, v. 43, n. 4, p. 476, doi. 10.5114/ceji.2018.81347

By:

SHAIK, YASDANI;
CARAFFA, ALESSANDRO;
RONCONI, GIANPAOLO;
LESSIANI, GIANFRANCO;
CONTI, PIO

Publication type:

Article

Screening and characterisation of proteins interacting with the mitogen-activated protein kinase Crmapk in the fungus Clonostachys chloroleuca.

Published in:

Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-13899-3

By:

Lv, Binna;
Fan, Lele;
Li, Shidong;
Sun, Manhong

Publication type:

Article

Screening and characterisation of proteins interacting with the mitogen-activated protein kinase Crmapk in the fungus Clonostachys chloroleuca.

Published in:

Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-13899-3

By:

Lv, Binna;
Fan, Lele;
Li, Shidong;
Sun, Manhong

Publication type:

Article

Relative Bioavailability of Pediatric Oral Solution and Tablet Formulations of Trametinib in Adult Patients With Solid Tumors.

Published in:

Clinical Pharmacology in Drug Development, 2015, v. 4, n. 4, p. 287, doi. 10.1002/cpdd.152

By:

Cox, Donna S.;
Allred, Alicia;
Zhou, YanYan;
Infante, Jeffrey R.;
Gordon, Michael S.;
Bendell, Johanna;
Jones, Suzanne;
Burris, Howard;
Orford, Keith

Publication type:

Article

Editorial: Novel preclinical model, biomarker, treatment and drug delivery to address immune evasion in cancer.

Published in:

Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1486819

By:

Chun-Wai Mai;
Jilkova, Zuzana Macek;
Dua, Kamal;
Bey-Hing Goh

Publication type:

Article

Gene expression analysis in children with complex seizures due to influenza A(H1N1)pdm09 or rotavirus gastroenteritis.

Published in:

Journal of NeuroVirology, 2014, v. 20, n. 1, p. 73, doi. 10.1007/s13365-013-0231-5

By:

Tsuge, Mitsuru;
Oka, Takashi;
Yamashita, Nobuko;
Saito, Yukie;
Fujii, Yosuke;
Nagaoka, Yoshiharu;
Yashiro, Masato;
Tsukahara, Hirokazu;
Morishima, Tsuneo

Publication type:

Article

Cell cycle-dependent Cdc25C phosphatase determines cell survival by regulating apoptosis signal-regulating kinase 1.

Published in:

Cell Death & Differentiation, 2015, v. 22, n. 10, p. 1605, doi. 10.1038/cdd.2015.2

By:

Cho, Y-C;
Park, J E;
Park, B C;
Kim, J-H;
Jeong, D G;
Park, S G;
Cho, S

Publication type:

Article

The Role of Hypothalamic H1 Receptor Antagonism in Antipsychotic-Induced Weight Gain.

Published in:

CNS Drugs, 2013, v. 27, n. 6, p. 423, doi. 10.1007/s40263-013-0062-1

By:

He, Meng;
Deng, Chao;
Huang, Xu-Feng

Publication type:

Article

Natural variation in a type-A response regulator confers maize chilling tolerance.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-25001-y

By:

Zeng, Rong;
Li, Zhuoyang;
Shi, Yiting;
Fu, Diyi;
Yin, Pan;
Cheng, Jinkui;
Jiang, Caifu;
Yang, Shuhua

Publication type:

Article