Works matching DE "GLUCURONOSYLTRANSFERASE"

Results: 512

Chemo‐Enzymatic Synthesis of Long‐Chain Oligosaccharides for Studying Xylan‐Modifying Enzymes.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 26, p. 1, doi. 10.1002/chem.202203941

By:

Álvarez‐Martínez, Ignacio;
Ruprecht, Colin;
Senf, Deborah;
Wang, Hsin‐tzu;
Urbanowicz, Breeanna R.;
Pfrengle, Fabian

Publication type:

Article

Contribution of UDP-glucuronosyltransferases 1A9 and 2B7 to the glucuronidation of indomethacin in the human liver.

Published in:

European Journal of Clinical Pharmacology, 2007, v. 63, n. 3, p. 289, doi. 10.1007/s00228-007-0261-0

By:

Mano, Yuji;
Usui, Takashi;
Kamimura, Hidetaka

Publication type:

Article

Inhibitory potential of nonsteroidal anti-inflammatory drugs on UDP-glucuronosyltransferase 2B7 in human liver microsomes.

Published in:

European Journal of Clinical Pharmacology, 2007, v. 63, n. 2, p. 211, doi. 10.1007/s00228-006-0241-9

By:

Mano, Yuji;
Usui, Takashi;
Kamimura, Hidetaka

Publication type:

Article

UGT1A polymorphisms in a Swedish cohort and a human diversity panel, and the relation to bilirubin plasma levels in males and females.

Published in:

European Journal of Clinical Pharmacology, 2006, v. 62, n. 10, p. 829, doi. 10.1007/s00228-006-0166-3

By:

Odeberg, J. Mercke;
Andrade, J.;
Holmberg, K.;
Hoglund, P.;
Malmqvist, U.;
Odeberg, J.

Publication type:

Article

A pharmacokinetic study of paracetamol in Thai β-thalassemia/HbE patients.

Published in:

European Journal of Clinical Pharmacology, 2006, v. 62, n. 9, p. 743, doi. 10.1007/s00228-006-0167-2

By:

Tankanitlert, Jeeranut;
Howard, Thad A.;
Temsakulphong, Anusorn;
Sirankapracha, Pornpan;
Morales, Noppawan;
Sanvarinda, Yupin;
Fucharoen, Pranee;
Ware, Russell E.;
Fucharoen, Suthat;
Chantharaksri, Udom

Publication type:

Article

Morphine glucuronide-to-morphine plasma ratios are unaffected by the UGT2B7 H268Y and UGT1A1*28 polymorphisms in cancer patients on chronic morphine therapy.

Published in:

European Journal of Clinical Pharmacology, 2002, v. 58, n. 5, p. 353, doi. 10.1007/s00228-002-0490-1

By:

Holthe, Monica;
Klepstad, Pål;
Zahlsen, Kolbjørn;
Borchgrevink, Petter C.;
Hagen, Lars;
Dale, Ola;
Kaasa, Stein;
Krokan, Hans E.;
Skorpen, Frank

Publication type:

Article

Effect of a conserved mutation in uridine diphosphate glucuronosyltransferase 1A1 and 1A6 on glucuronidation of a metabolite of flutamide.

Published in:

European Journal of Clinical Pharmacology, 2002, v. 58, n. 1, p. 11, doi. 10.1007/s00228-001-0417-2

By:

Ito, Masaki;
Yamamoto, Kazuo;
Maruo, Yoshihiro;
Sato, Hiroshi;
Fujiyama, Yoshihide;
Bamba, Tadao

Publication type:

Article

Sickle Cell Disease: A Multigenic Perspective of a Single-Gene Disorder.

Published in:

Medical Principles & Practice, 2005, v. 14, p. 15, doi. 10.1159/000086180

By:

Kutlar, Abdullah

Publication type:

Article

SOMP: web server for in silico prediction of sites of metabolism for drug-like compounds.

Published in:

Bioinformatics, 2015, v. 31, n. 12, p. 2046, doi. 10.1093/bioinformatics/btv087

By:

Rudik, Anastasia;
Dmitriev, Alexander;
Lagunin, Alexey;
Filimonov, Dmitry;
Poroikov, Vladimir

Publication type:

Article

Frequency of dihydropyrimidine dehydrogenase and UDP-glucuronosyltransferase 1A1 variants in cancer patients requiring chemotherapy: A single-center study in southern India.

Published in:

Journal of Clinical & Basic Research, 2023, v. 7, n. 1, p. 6, doi. 10.61186/jcbr.7.1.6

By:

Gangavarapu, Kevin;
Bora, Nandini Shyamali;
Srinivas, Maddali;
Hasan, Qurratulain

Publication type:

Article

Hepatic UDP-Glucuronosyltransferase in Rainbow Trout (Oncorhynchus mykiss) and Preliminary Assessment of Response to Pulp Mill Cooking Liquor.

Published in:

Bulletin of Environmental Contamination & Toxicology, 1999, v. 62, n. 5, p. 608, doi. 10.1007/s001289900918

By:

Sturm, A.;
Hodson, P. V.;
Carey, J. H.;
Hansen, P.-D.

Publication type:

Article

Effects of the environmental pollutants on heme oxygenase activity and cytochrome P-450 content in fish.

Published in:

Bulletin of Environmental Contamination & Toxicology, 1990, v. 44, n. 2, p. 189, doi. 10.1007/BF01700135

By:

Ariyoshi, Toshihiko;
Shiiba, Seiichi;
Hasegawa, Hiroyuki;
Arizono, Koji

Publication type:

Article

Glucuronidation: driving factors and their impact on glucuronide disposition.

Published in:

Drug Metabolism Reviews, 2017, v. 49, n. 2, p. 105, doi. 10.1080/03602532.2017.1293682

By:

Yang, Guangyi;
Ge, Shufan;
Singh, Rashim;
Basu, Sumit;
Shatzer, Katherine;
Zen, Ming;
Liu, Jiong;
Tu, Yifan;
Zhang, Chenning;
Wei, Jinbao;
Shi, Jian;
Zhu, Lijun;
Liu, Zhongqiu;
Wang, Yuan;
Gao, Song;
Hu, Ming

Publication type:

Article

Biotransformation of xenobiotics in the human colon and rectum and its association with colorectal cancer.

Published in:

Drug Metabolism Reviews, 2015, v. 47, n. 2, p. 199, doi. 10.3109/03602532.2014.996649

By:

Beyerle, Jolantha;
Frei, Eva;
Stiborova, Marie;
Habermann, Nina;
Ulrich, Cornelia M.

Publication type:

Article

Pharmacogenetics of isoniazid-induced hepatotoxicity.

Published in:

Drug Metabolism Reviews, 2015, v. 47, n. 2, p. 222, doi. 10.3109/03602532.2014.984070

By:

Perwitasari, Dyah Aryani;
Atthobari, Jarir;
Wilffert, Bob

Publication type:

Article

Transcriptional regulation of human UDP-glucuronosyltransferase genes.

Published in:

Drug Metabolism Reviews, 2014, v. 46, n. 4, p. 421, doi. 10.3109/03602532.2014.973037

By:

Hu, Dong Gui;
Meech, Robyn;
McKinnon, Ross A.;
Mackenzie, Peter I.

Publication type:

Article

UGT3A: novel UDP-glycosyltransferases of the UGT superfamily.

Published in:

Drug Metabolism Reviews, 2010, v. 42, n. 1, p. 43, doi. 10.3109/03602530903205823

By:

Meech, Robyn;
Mackenzie, Peter I.

Publication type:

Article

Renal UDP-glucuronosyltransferases and the glucuronidation of xenobiotics and endogenous mediators.

Published in:

Drug Metabolism Reviews, 2010, v. 42, n. 1, p. 60, doi. 10.3109/03602530903208561

By:

Knights, Kathleen M.;
Miners, John O.

Publication type:

Article

Use of transgenic mice in UDP-glucuronosyltransferase (UGT) studies.

Published in:

Drug Metabolism Reviews, 2010, v. 42, n. 1, p. 119, doi. 10.3109/03602530903208983

By:

Ou, Zhimin;
Huang, Min;
Zhao, Lizi;
Xie, Wen

Publication type:

Article

Insights on membrane topology and structure/function of UDP-glucuronosyltransferases.

Published in:

Drug Metabolism Reviews, 2010, v. 42, n. 1, p. 154, doi. 10.3109/03602530903209270

By:

Magdalou, Jacques;
Fournel-Gigleux, Sylvie;
Ouzzine, Mohamed

Publication type:

Article

Warfarin and UDP-glucuronosyltransferases: writing a new chapter of metabolism.

Published in:

Drug Metabolism Reviews, 2010, v. 42, n. 1, p. 53, doi. 10.3109/03602530903209395

By:

Jones, Drew R.;
Moran, Jeffery H.;
Miller, Grover P.

Publication type:

Article

UGT genomic diversity: beyond gene duplication.

Published in:

Drug Metabolism Reviews, 2010, v. 42, n. 1, p. 22, doi. 10.3109/03602530903210682

By:

Guillemette, Chantal;
Lévesque, Eric;
Harvey, Mario;
Bellemare, Judith;
Menard, Vincent

Publication type:

Article

UDP-glucuronosyltransferases (UGTs): from purification of Ah-receptor–inducible UGT1A6 to coordinate regulation of subsets of CYPs, UGTs, and ABC transporters by nuclear receptors.

Published in:

Drug Metabolism Reviews, 2010, v. 42, n. 1, p. 5, doi. 10.3109/03602530903205492

By:

Bock, Karl W.;
Bock-Hennig, Barbara S.

Publication type:

Article

Potential role of UGT pharmacogenetics in cancer treatment and prevention: focus on tamoxifen and aromatase inhibitors.

Published in:

Drug Metabolism Reviews, 2010, v. 42, n. 1, p. 176, doi. 10.3109/03602530903208652

By:

Lazarus, Philip;
Sun, Dongxiao

Publication type:

Article

Interindividual variability in hepatic drug glucuronidation: studies into the role of age, sex, enzyme inducers, and genetic polymorphism using the human liver bank as a model system.

Published in:

Drug Metabolism Reviews, 2010, v. 42, n. 1, p. 202, doi. 10.3109/03602530903209288

By:

Court, Michael H.

Publication type:

Article

The regulation of UDP-glucuronosyltransferase genes by tissue-specific and ligand-activated transcription factors.

Published in:

Drug Metabolism Reviews, 2010, v. 42, n. 1, p. 95, doi. 10.3109/03602530903209544

By:

Mackenzie, Peter I.;
Hu, Dong Gui;
Gardner-Stephen, Dione A.

Publication type:

Article

The prediction of drug-glucuronidation parameters in humans: UDP-glucuronosyltransferase enzyme-selective substrate and inhibitor probes for reaction phenotyping and in vitro–in vivo extrapolation of drug clearance and drug-drug interaction potential

Published in:

Drug Metabolism Reviews, 2010, v. 42, n. 1, p. 189, doi. 10.3109/03602530903210716

By:

Miners, John O.;
Mackenzie, Peter I.;
Knights, Kathleen M.

Publication type:

Article

Takashi Iyanagi: UGT1 gene complex: from Gunn rat to human.

Published in:

Drug Metabolism Reviews, 2010, v. 42, n. 1, p. 13, doi. 10.3109/03602530903205757

By:

Ikushiro, Shinichi

Publication type:

Article

The crystal structure of human UDP-glucuronosyltransferase 2B7 C-terminal end is the first mammalian UGT target to be revealed: the significance for human UGTs from both the 1A and 2B families.

Published in:

Drug Metabolism Reviews, 2010, v. 42, n. 1, p. 128, doi. 10.3109/03602530903209049

By:

Radominska-Pandya, Anna;
Bratton, Stacie M.;
Redinbo, Matthew R.;
Miley, Michael J.

Publication type:

Article

UDP-glucuronosyltransferases (UGTs) in neuro-olfactory tissues: expression, regulation, and function.

Published in:

Drug Metabolism Reviews, 2010, v. 42, n. 1, p. 71, doi. 10.3109/03602530903208363

By:

Heydel, Jean-Marie;
Holsztynska, Elzbieta J;
Legendre, Arièle;
Thiebaud, Nicolas;
Artur, Yves;
Bon, Anne-Marie Le

Publication type:

Article

Modulation of UDP-glucuronosyltransferase activity by protein-protein association.

Published in:

Drug Metabolism Reviews, 2010, v. 42, n. 1, p. 140, doi. 10.3109/03602530903208579

By:

Ishii, Yuji;
Takeda, Shuso;
Yamada, Hideyuki

Publication type:

Article

Interaction Between Valproic Acid and Carbapenem Antibiotics.

Published in:

Drug Metabolism Reviews, 2007, v. 39, n. 4, p. 647, doi. 10.1080/03602530701690341

By:

Mori, Hitomi;
Takahashi, Kazuhiko;
Mizutani, Takaharu

Publication type:

Article

Pharmacogenetics of Uridine Diphosphoglucuronosyltransferase (UGT) 1A Family Members and its Role in Patient Response to Irinotecan*.

Published in:

Drug Metabolism Reviews, 2006, v. 38, n. 3, p. 393, doi. 10.1080/03602530600739835

By:

Nagar, Swati;
Blanchard, Rebecca L.

Publication type:

Article

167. LITHOCHOLIC ACID DECREASES EXPRESSION OF UGT2B7 IN CACO2 CELLS THROUGH FARNESOID X RECEPTOR ANTAGONIST ACTIVITY.

Published in:: 2003
Publication type:: Abstract

155. FIBRATES AND GLITAZONES STIMULATE THEIR INACTIVATION THROUGH PPAR-DEPENDENT UP-REGULATION OF THE DRUG METABOLIZING UGT1A9 ENZYME.

Published in:: 2003
Publication type:: Abstract

11. FUCTIONAL CONSEQUENCES OF INTERINDIVIDUAL VARIATION IN HUMAN SULFOTRANSFERASE 1A1 AND UDP-GLUCURONOSYLTRANSFERASE 1A6.

Published in:: 2003
Publication type:: Abstract

8. STRUCTURE/FUNCTION OF HUMAN UDP-GLUCURONOSYLTRANSFERASES.

Published in:: 2003
Publication type:: Abstract

379. HETEROLOGOUS EXPRESSION OF UDP-GLUCURONOSYLTRANSFERASES IN INSECT CELLS.

Published in:: 2002
Publication type:: Abstract

391. DIFFERENTIAL MODULATION OF HUMAN UGT1A1 ACTIVITY.

Published in:: 2002
Publication type:: Abstract

387. EFFECTS OF INCUBATION CONDITIONS ON THE ENZYME KINETICS OF UDP- GLUCURONOSYLTRANSFERASES.

Published in:: 2002
Publication type:: Abstract

375. STUDY OF THE SUBSTRATE SPECIFICITY OF UGT2B7 AND PROTEIN OLIGOMERIZATION.

Published in:: 2002
Publication type:: Abstract

374. ALTERNATIVE TRANSCRIPT-SPECIFIC EXPRESSION FOR HUMAN PXR CORRELATES WITH THE EXPRESSION OF UGT2B7 IN HUMAN LIVER AND INTESTINE.

Published in:: 2002
Publication type:: Abstract

373. INDEPENDENT REGULATION OF UGT 1A AND 2B EXPRESSION AND PXRCORRELATED EXPRESSION UGT2B7 IN HUMAN LIVERS.

Published in:: 2002
Publication type:: Abstract

372. IDENTIFICATION OF HUMAN UDP-GLUCURONOSYLTRANSFERASE ENZYME(S) RESPONSIBLE FOR THE GLUCURONIDATION OF POSACONAZOLE (SCH 56592).

Published in:: 2002
Publication type:: Abstract

The role of hepatic and extrahepatic UDP-glucuronosyltransferases in human drug metabolism.

Published in:

Drug Metabolism Reviews, 2001, v. 33, n. 3/4, p. 273, doi. 10.1081/DMR-120000653

By:

Fisher, Michael B.;
Paine, Mary F.;
Strelevitz, Timothy J.;
Wrighton, Steven A.

Publication type:

Article

STRUCTURAL AND FUNCTIONAL STUDIES OF UDP-GLUCURONOSYLTRANSFERASES*.

Published in:

Drug Metabolism Reviews, 1999, v. 31, n. 4, p. 817, doi. 10.1081/DMR-100101944

By:

RADOMINSKA-PANDYA, ANNA;
CZERNIK, PIOTR J.;
LITTLE, JOANNA M.;
BATTAGLIA, ERIC;
MACKENZIE, PETER I.

Publication type:

Article

New Insights into SN‐38 Glucuronidation: Evidence for the Important Role of UDP Glucuronosyltransferase 1A9.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2018, v. 122, n. 4, p. 424, doi. 10.1111/bcpt.12929

By:

Xiao, Ling;
Zhu, Liangliang;
Li, Wenjuan;
Li, Conghu;
Cao, Yunfeng;
Ge, Guangbo;
Sun, Xiaoyu

Publication type:

Article

Human UDP-Glucuronosyltransferases 1A1, 1A3, 1A9, 2B4 and 2B7 are Inhibited by Diethylstilbestrol.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2016, v. 119, n. 5, p. 505, doi. 10.1111/bcpt.12618

By:

Zhu, Liangliang;
Xiao, Ling;
Li, Wenjuan;
Zhang, Yuan;
Han, Wenwen;
Zhu, Yu;
Ge, Guangbo;
Yang, Ling

Publication type:

Article

Human UDP-glucuronosyltransferase UGT1A4 forms tertiary N-glucuronides predominately with the energetically less favored tautomer of substituted 1 H-indazole (benzpyrazole).

Published in:

Journal of Analytical Science & Technology, 2017, v. 8, n. 1, p. 1, doi. 10.1186/s40543-017-0120-2

By:

Fredenhagen, Andreas;
Eggimann, Fabian;
Kittelmann, Matthias;
Lochmann, Thomas;
Kühnöl, Jürgen

Publication type:

Article

Distribution of uridine diphosphate glucuronosyltransferase 1A polymorphisms and their role in irinotecan-induced toxicity in patients with cancer.

Published in:

Oncology Letters, 2017, v. 14, n. 5, p. 5743, doi. 10.3892/ol.2017.6933

By:

YANG WANG;
CUIHUA YI;
YAWEI WANG;
HUI LI;
BEI LI;
DAN WANG;
JINTONG DU;
LIAN LIU;
XIUWEN WANG

Publication type:

Article