Found: 21
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Artificial intelligence for prediction of biological activities and generation of molecular hits using stereochemical information.
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- Journal of Computer-Aided Molecular Design, 2023, v. 37, n. 12, p. 791, doi. 10.1007/s10822-023-00539-9
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- Article
Novel PARP-1 Inhibitor Scaffolds Disclosed by a Dynamic Structure-Based Pharmacophore Approach.
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- PLoS ONE, 2017, v. 12, n. 1, p. 1, doi. 10.1371/journal.pone.0170846
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- Article
Combining Virtual Screening Protocol and In Vitro Evaluation towards the Discovery of BACE1 Inhibitors.
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- Biomolecules (2218-273X), 2020, v. 10, n. 4, p. 535, doi. 10.3390/biom10040535
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- Article
Revisiting Proteasome Inhibitors: Molecular Underpinnings of Their Development, Mechanisms of Resistance and Strategies to Overcome Anti-Cancer Drug Resistance.
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- Molecules, 2022, v. 27, n. 7, p. 2201, doi. 10.3390/molecules27072201
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- Article
The Presence of a Cyclohexyldiamine Moiety Confers Cytotoxicity to Pentacyclic Triterpenoids.
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- Molecules, 2021, v. 26, n. 7, p. 2102, doi. 10.3390/molecules26072102
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- Article
Melatonin Administration Accelerates Puberty Onset in Mice by Promoting FSH Synthesis.
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- Molecules, 2021, v. 26, n. 5, p. 1474, doi. 10.3390/molecules26051474
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- Article
Development of a Liquid Chromatography/Mass Spectrometry-Based Inhibition Assay for the Screening of Steroid 5-α Reductase in Human and Fish Cell Lines.
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- Molecules, 2021, v. 26, n. 4, p. 893, doi. 10.3390/molecules26040893
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- Article
Ubiquitin Ligases at the Heart of Skeletal Muscle Atrophy Control.
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- Molecules, 2021, v. 26, n. 2, p. 407, doi. 10.3390/molecules26020407
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- Article
Synthesis and Antiproliferative Activity of Novel Heterocyclic Glycyrrhetinic Acid Derivatives.
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- Molecules, 2019, v. 24, n. 4, p. 766, doi. 10.3390/molecules24040766
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- Article
Computational Approaches for the Discovery of Human Proteasome Inhibitors: An Overview.
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- Molecules, 2016, v. 21, n. 7, p. 927, doi. 10.3390/molecules21070927
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- Article
Bismuth(III) Triflate-Based Catalytic Direct Opening of Oleanolic Hydroxy-γ-lactones to Afford 12-Oxo-28-carboxylic Acids.
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- Advanced Synthesis & Catalysis, 2011, v. 353, n. 14/15, p. 2637, doi. 10.1002/adsc.201100155
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- Article
Bismuth(III) Reagents in Steroid and Terpene Chemistry.
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- Molecules, 2011, v. 16, n. 4, p. 2884, doi. 10.3390/molecules16042884
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- Article
Decoding the secrets: how conformational and structural regulators inhibit the human 20S proteasome.
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- Frontiers in Chemistry, 2024, p. 1, doi. 10.3389/fchem.2023.1322628
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- Article
Antileishmanial Activity of Semisynthetic Lupane Triterpenoids Betulin and Betulinic Acid Derivatives: Synergistic Effects with Miltefosine.
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- PLoS ONE, 2014, v. 9, n. 3, p. 1, doi. 10.1371/journal.pone.0089939
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- Article
Semisynthetic Ursolic Acid Fluorolactone Derivatives Inhibit Growth with Induction of p21<sup>waf1</sup> and Induce Apoptosis with Upregulation of NOXA and Downregulation of c-FLIP in Cancer Cells.
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- ChemMedChem, 2012, v. 7, n. 9, p. 1635, doi. 10.1002/cmdc.201200282
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- Article
Deep generative model for therapeutic targets using transcriptomic disease-associated data—USP7 case study.
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- Briefings in Bioinformatics, 2022, v. 23, n. 4, p. 1, doi. 10.1093/bib/bbac270
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- Article
Chemical Patterns of Proteasome Inhibitors: Lessons Learned from Two Decades of Drug Design.
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- International Journal of Molecular Sciences, 2019, v. 20, n. 21, p. 5326, doi. 10.3390/ijms20215326
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- Article
PROteolysis‐Targeting Chimeras (PROTACs) in leukemia: overview and future perspectives.
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- MedComm, 2024, v. 5, n. 6, p. 1, doi. 10.1002/mco2.575
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- Article
New Scaffolds of Proteasome Inhibitors: Boosting Anticancer Potential by Exploiting the Synergy of In Silico and In Vitro Methodologies.
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- Pharmaceuticals (14248247), 2023, v. 16, n. 8, p. 1096, doi. 10.3390/ph16081096
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- Article
Bioactive Bismuth Compounds: Is Their Toxicity a Barrier to Therapeutic Use?
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- International Journal of Molecular Sciences, 2024, v. 25, n. 3, p. 1600, doi. 10.3390/ijms25031600
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- Article
MDM2-Based Proteolysis-Targeting Chimeras (PROTACs): An Innovative Drug Strategy for Cancer Treatment.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 19, p. 11068, doi. 10.3390/ijms231911068
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- Article